439-The Oral–Gut Microbiome Axis in Health and Disease
This review article examines the oral–gut microbiome axis, highlighting how the mouth serves as a primary gateway for microbes to influence the rest of the body. While physico-chemical barriers typically keep these two ecosystems distinct, oral bacteria can migrate to the intestines through the digestive or circulatory systems, especially when health is compromised. The authors explain how this microbial transfer is linked to the development and worsening of inflammatory bowel disease and colorectal cancer. Furthermore, the text details how periodontal diseases can trigger systemic…
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