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Latest / WhiteBoard Medicine - Emergency And Critical Care

#203 Lactate Explained | Lactic Acidosis, Type A vs Type B, and Prognosis in Critical Illness

Lactate is one of the most commonly ordered labs in emergency medicine and critical care—yet it’s often misunderstood. In this comprehensive review, we break down everything clinicians need to know about lactate and lactic acidosis, from basic physiology to prognostic significance in critical illness. We cover: • What lactate is and how it’s produced • Aerobic vs anaerobic lactate generation • Type A vs Type B lactic acidosis • Lactate in sepsis, shock, and hypoperfusion • Non-hypoxic causes of elevated lactate • Lactate clearance and trends • Prognostic value of lactate in critical illness •…

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