Latest / Intellectual Medicine / Think Twice Before Getting Radiation Treatment For Prostate
Transcript
- 0:00We do treatments that are toxic and harmful to us so we don't
- 0:04die from the disease we're trying to treat.
- 0:07That's pretty fundamental. Radiation is a carcinogen.
- 0:11It causes cancer that has to be weighed against whatever benefit
- 0:17it may give us. You can't wash out the
- 0:20radiation. It's permanent.
- 0:22You see, doctors are motivated by not missing anything.
- 0:28They're not thinking about you in three or five or ten years.
- 0:31So radiation today doesn't worry them.
- 0:35So you, you have to be the one that is absurd.
- 0:41Think twice before getting radiation therapy.
- 0:44Maybe it should be think three times or four times.
- 0:49Let's not bury the headline, folks.
- 0:52There's never been a placebo-controlled study
- 0:55demonstrating that a radiating the prostate gland or the pelvis
- 1:00does any good to prevent men from dying from prostate cancer.
- 1:05And after all, isn't that what we're after?
- 1:08We do treatments that are toxic and harmful to us so we don't
- 1:12die from the disease we're trying to treat.
- 1:15That's pretty fundamental. But you take something like
- 1:19radiation, Here's what's unequivocal, settled science, No
- 1:24debate. Radiation is a carcinogen.
- 1:27It causes cancer, 100% risk that has to be weighed against
- 1:34whatever benefit it may give us. So globally speaking, I'm of the
- 1:39opinion that doctors radiate patients far too often.
- 1:43We do this without regard to lifetime accumulation.
- 1:46Folks, you can't wash out the radiation.
- 1:49It's permanent. It is a cumulative toxicity.
- 1:54Each X-ray gets a little worse than the last one.
- 1:58Every X-ray counts. I haven't let my dentist X-ray
- 2:01my teeth in 20 years. He hates me for that.
- 2:04Well, probably didn't hate me. Said, what are you radiating him
- 2:08for? He said, well, he might have a
- 2:10cavity back in there. I might, but if I do, it's going
- 2:14to let me know. So you you have to be the one
- 2:18that is assertive when they want to irradiate you challenge them.
- 2:23My wife had an accident. She was having trouble with her
- 2:26chest pain. They want to do a plain X-ray.
- 2:30OK, we could live with that. Then they want to do a CAT scan.
- 2:34Well, so why? They said, well, she might have
- 2:36a collapsed lung in there. OK.
- 2:39If it's collapsed, she's going to have trouble breathing,
- 2:41right? Yeah, we can.
- 2:42We can wait and see if the symptom occurs.
- 2:45You see, doctors are motivated by not missing anything.
- 2:50They're not thinking about you in three or five or ten years.
- 2:54So radiation today doesn't worry them.
- 2:58Now let's get back to the issue at hand.
- 3:00A man with prostate cancer. They want to irradiate your
- 3:03prostate gland. Here's the bottom line.
- 3:06Men. The Protect T trial compared men
- 3:10who did nothing, men with prostate cancer who did
- 3:15literally nothing. Compare them to men who had
- 3:19irradiated their pelvis. That's not a trivial endeavour,
- 3:23by the way. They irradiate your pelvis.
- 3:25There are a lot of things that live really close to each other.
- 3:28There is the rectum, the bladder and yes, sexual function.
- 3:34So when you got a lot of potential harm to be done,
- 3:37what's the upside? The Protect T trial after 15
- 3:42years, the men who did nothing had a 2.7% rate of death from
- 3:48prostate cancer. How about the guys who got it
- 3:50radiated? Yeah, their death rate from
- 3:52prostate cancer was 2.5%. Do not let them mislead and
- 3:58misstate the outcome. Radiation therapy does not cure
- 4:04cancer. When men are told we can cure
- 4:08this cancer, I want to see the proof I have it.
- 4:13It's disturbing to me. It'd be one thing if the
- 4:16treatment was benign. This won't hurt you.
- 4:20You're not going to lose sexual vitality if the treatment is
- 4:24benign. We can tolerate an outcome
- 4:27that's perhaps suboptimal or an outcome that's not ideal.
- 4:31I mean, the perfect outcome is a treatment that eliminates the
- 4:35disease and causes no harm. Radiation is the opposite.
- 4:38It causes harm 100%. I don't care what they tell you,
- 4:43folks, they're not really disclosing the extent of that
- 4:46harm. They're looking at it through
- 4:48their own lens. How do I know that?
- 4:51Here's a study. They looked at men who had
- 4:53radiation therapy, and in this study they were comparing
- 4:56different levels of radiation. But the telling part of this had
- 5:00to do with what they consider to be minor, acute, short term
- 5:06outcome. Minor.
- 5:07Minor by whose definition? We're looking at a 30% rate of
- 5:14difficulty with sexual function, 20% rate of difficulty with
- 5:19hormones, 10% rate of difficulty with rectal function.
- 5:25And that's just the short term side effects.
- 5:28They describe that as, you know, minor.
- 5:31Not for me. If I'm the guy who's having
- 5:34trouble with my bowels, I'm the guy who's having trouble with
- 5:36erections. I'm the guy who's losing
- 5:38hormonal vitality. Don't call that minor.
- 5:41That's insulting to my sense of intelligence.
- 5:44And on top of that, don't tell me you cured my cancer.
- 5:48When you take a man who has early stage prostate cancer and
- 5:52you tell him we're going to cure you with radiation, they're
- 5:56giving you a treatment that's never been proven to work and
- 6:00causes harm. The fact that most men don't die
- 6:04from prostate cancer after being irradiated has probably very
- 6:09little to do with the radiation and likely just their fate.
- 6:14They weren't destined to die from it.
- 6:16I understand it, man. It's tough.
- 6:19It's tough to be told you have prostate cancer.
- 6:22What can I do about that? Saith the man.
- 6:25Well, we can take out your prostate, Glen.
- 6:27It's a little bit harsh, don't you think?
- 6:29I mean, most men in the early stage feel pretty darn good.
- 6:34Strength is good, vitality is good.
- 6:36Now they're whacking out the gland.
- 6:38Then comes the difficulty with sexual function.
- 6:41Then comes difficulty with bladder control.
- 6:43For what gain? Again, we go back to the long
- 6:46term trial. The PIVOT study looked at men
- 6:49who had the gland removed versus men who did nothing, nothing.
- 6:56And 20 years later, they had the same death rate from prostate
- 7:02cancer. Think about that.
- 7:05They take the gland out. Hey, we caught this early.
- 7:08Isn't that great news? We're going to cut it out before
- 7:11it spreads. Most cancers spread at an early
- 7:16stage by cellular dissemination. So gross anatomy, we think we
- 7:21got it all. Ain't the truth.
- 7:25It escapes in a cellular level and those cells divide.
- 7:30So be careful about how you are guided.
- 7:34Be prepared to just say no, you don't have to get a biopsy.
- 7:41In fact, in my opinion, they're pointless.
- 7:44Now why do I say that? Because the information you gain
- 7:48is going to guide you toward one of two conventional pathways,
- 7:52surgical removal or radiation. Very good studies looking at
- 7:57long term outcomes have not seen a benefit to either of these
- 8:01treatments. I don't care how focal it is, I
- 8:04don't care how fancy they make it seem.
- 8:06I don't care how much they enhanced it.
- 8:08In their mind, they've never proven the benefit against the
- 8:14placebo and if anything the nearest thing to that, the
- 8:18Protect T trial, 15 years, the nearest thing to that showed no
- 8:23benefit at all. Radiation.
- 8:26What about the harm? Increased rate of leukemia,
- 8:29lymphoma, myelodysplasia, bone marrow damage can lead to
- 8:34leukemias, Radiation proctitis, the late effect from radiation.
- 8:40Now we all know that getting a sunburn is bad for us.
- 8:44That's a spit compared to radiation.
- 8:47Nevertheless, it's analogous. You get a sunburn, it hurts in
- 8:51the moment. So too, radiation therapy.
- 8:55The real harm comes 1015 years later when the skin cancer pops
- 8:59up. That's how it works.
- 9:01Guys with radiation to the pelvis, you'll feel not so good
- 9:06when they do it. Diarrhea, fatigue, radiation is
- 9:11poisonous. And then you're going to
- 9:14recover. You're going to feel OK and
- 9:15they're going to say, hey, it worked.
- 9:17Your PSA went down. Much Ado about nothing.
- 9:20I don't care about APSA number that much, I care about your
- 9:24health and vitality. And there's way too much
- 9:27interpretation placed on APSA number.
- 9:30Did it go up? Did it go down?
- 9:31Oh my goodness. Then comes the real harm, 5 and
- 9:3610 years later. As always is the case with
- 9:40radiation, the real harm is delayed radiation proctitis.
- 9:45I've had men in my practice who had radiation done before.
- 9:50They knew better. Now they're walking around
- 9:52leaking stool. They can't control their poop.
- 9:57How'd you like to live like that?
- 9:59Did they tell you that when you signed the consent?
- 10:02Oh, and if that's not enough? Radiation cystitis.
- 10:06The bladder becomes friable, irritable.
- 10:10It bleeds. You pee, blood.
- 10:12The bladder itself becomes stiff.
- 10:15Now they've developed barriers that they can put in to try to
- 10:19reduce the amount of radiation hitting these vital organs.
- 10:24What a joke. The difference is cellular.
- 10:27These organs are flush up against one another.
- 10:31Hey, here's what I'll believe when the day comes when they
- 10:34say, you know what, this radiation is so safe.
- 10:37I'm going to sit in the chair right next to you while you get
- 10:40irradiated. No, they dodge out of the room.
- 10:43Hide behind the lead curtain. So should you get radiation
- 10:47therapy, think twice. I'm strongly of the opinion that
- 10:53it has no value based upon the research I've observed and the
- 10:57outcomes I have seen. Now another problem.
- 11:02They'll say if you get your prostate removed.
- 11:06Here's another null study. They looked at men who had the
- 11:10prostate gland removed. OK, so that's a bad thing in the
- 11:12first place. Then they have two different
- 11:15kinds of radiation. They're going to offer these men
- 11:17adjuvant, which means immediately take out the the the
- 11:20prostate and, you know, wait for recovery and then we're going to
- 11:23radiate you. Then they compared those men to
- 11:28the men who didn't do radiation. And they waited and they waited.
- 11:32And when the PSA level started to go up again, they irradiated
- 11:36them. They call that salvage
- 11:38radiation. I have a lot of problems with
- 11:41these definitions, folks. First, APSA level going up is
- 11:46not justification in my opinion, for severe toxic therapy, be it
- 11:51radiation or castration. I don't think you should do
- 11:55either just because the PSA goes up.
- 11:57It's premature and their definition of a biochemical
- 12:02recurrence, if it goes up two points above the baseline, that
- 12:06ain't much. I've seen people go up two
- 12:08points after a long bike ride, so you got to be very careful
- 12:13about the path that is being pointed toward you.
- 12:16The idea of adjuvant radiation therapy versus salvage, There
- 12:21was no difference in outcomes whether they did radiation right
- 12:24away or they waited sometimes up to 8 years.
- 12:28Why was there no difference? Because it doesn't work and it
- 12:33didn't work adjuvant and it doesn't work long term.
- 12:36I'm still waiting for evidence of benefit.
- 12:39But you know, we're up against a multibillion dollar juggernaut.
- 12:42That's one variable. We're up against doctors who
- 12:47sincerely believe that they're helping you.
- 12:51And their belief is reinforced by the correlation between their
- 12:54therapy and a lack of cancer coming back, in which case the
- 12:59cancer probably going to come back anyhow.
- 13:02When the man comes in, he's saying, you know, Doc, I'm
- 13:04leaking stool, I can't get an erection.
- 13:06I feel awful. The doctor says, yeah, but
- 13:08you're not dead. And the guy nods accordingly.
- 13:12Yeah, you're right. You're right.
- 13:15I've heard this story too much. Talked to a man just the other
- 13:18day. She told me about his dad.
- 13:20He said he remember the last 10 years of his life, he had
- 13:23prostatectomy. He said all I remember was how
- 13:27sad he was the last 10 years of his life before he died.
- 13:32Or unpleasant, depressing. This man is no way to live.
- 13:37Fighting cancer like a man. It's an option you can embrace.
- 13:43It gives you the opportunity to hold on to vitality.
- 13:48Does it guarantee you're not going to die from cancer?
- 13:51No, doesn't guarantee that. It guarantees you're not going
- 13:55to be harmed by all these aggressive therapies.
- 13:58And it guarantees you you're not going to sit on your hands and
- 14:01just hope. This is what we need to do.
- 14:04We need to have another pathway opened up in front of us.
- 14:08Radiation, not now, not later, not ever.
- 14:13There is one niche for radiation.
- 14:16When or if the cancer goes to your bone and there's a targeted
- 14:21area that they can hit with radiation, it can reduce pain.
- 14:25In some cases it can help prevent a pathological fracture
- 14:30from happening. So I'm talking about pelvic
- 14:32radiation. That's the one that I think has
- 14:34zero merit. Targeted radiation late in the
- 14:38disease when you have metastatic to the bone can alleviate pain
- 14:42and I think that that's a legitimate use.
- 14:44That's one of the few spots. But now we're talking comfort at
- 14:47the tail end of life. We're not worried so much about
- 14:50a five year issue. When you're young, you got to
- 14:54think twice, think three times. How do you want to live?
- 14:58Ask that question. And do you have to do radiation?
- 15:02Of course you don't. Do you have alternatives?
- 15:06Yeah. And that's why you're tuning in
- 15:07this podcast, so we can learn about them together.
- 15:10Well, thanks for taking some time.
- 15:12I want you to take your time. Think hard.
- 15:15It's your life. It's your body.
- 15:18It's your choice. You have time, Then this cancer
- 15:22moves slowly. Don't let anybody shuffle you
- 15:25into a treatment until you're absolutely ready.
- 15:29And if you choose radiation, do so with a clear mind, with good
- 15:33research, and with confidence in the path you chose because it
- 15:38suits your philosophy. It's not what I would choose.
- 15:42I would never do it. Nope, never.
- 15:45I'm thinking. Not a circumstance I can think
- 15:48of with regard to prostate cancer that I would allow them
- 15:51to light me up. Nope.
- 15:54I'm going to keep my vitality. All right, guys, till next time
- 15:57we'll continue the conversation.