Latest / The You Project / #1866 Why Making Babies is Getting Harder - David Gillespie

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#1866 Why Making Babies is Getting Harder - David Gillespie · The You Project

• 0:01
  Speaker 1: Oh good a team. Welcome to another instorming the show.
• 0:03
  Speaker 1: Tiffany and Cook, David James, Patrick Gillespie. It's me Jumbo,
• 0:06
  Speaker 1: steering the ship as I do. Let's go with the
• 0:10
  Speaker 1: lifeblood of the show.
• 0:11
  Speaker 2: Tip.
• 0:12
  Speaker 3: Hi, Hi, that's me.
• 0:14
  Speaker 1: Hello, Yeah, that's you. How are you really good?
• 0:18
  Speaker 4: Thanks? Been Ben sparring blind blokes again today.
• 0:23
  Speaker 1: I saw that. I saw that. Tell just tell our
• 0:26
  Speaker 1: listeners who didn't hear that chat we had and tell
• 0:29
  Speaker 1: Gillespo that you've been punching people with visual impairments in
• 0:33
  Speaker 1: the face.
• 0:34
  Speaker 4: Yeah. I thought it'd be an easy win, but pretty
• 0:37
  Speaker 4: good accuracy for someone who can't see. Ben Pettingill's been
• 0:43
  Speaker 4: a guest on my show before and he's doing a
• 0:46
  Speaker 4: boxing event against blindfolded opponents for an event called I'll
• 0:52
  Speaker 4: give him a shout out because one of your listeners
• 0:54
  Speaker 4: said that it was her nephew let Me Get It
• 0:58
  Speaker 4: Out podcast Royale, Queensland this weekend.
• 1:02
  Speaker 1: Yeah, someone said that. I mean, I'm all four fundraisers
• 1:06
  Speaker 1: and all four charity but I'm just I don't know
• 1:09
  Speaker 1: that blind people fighting is I mean, I don't know.
• 1:13
  Speaker 1: I just I just I just see traumatic brain injury.
• 1:17
  Speaker 1: That's all.
• 1:17
  Speaker 4: I think, well, I was the only one with traumatic
• 1:20
  Speaker 4: brain injury. Ben was doing just fine. You know, he's
• 1:24
  Speaker 4: so sneaky. He can hear everything. I've got to breathe
• 1:27
  Speaker 4: really quiet, and if I manage a moment where he
• 1:30
  Speaker 4: hasn't heard where I've positioned, I just stay there and
• 1:33
  Speaker 4: crouch and just take a minute.
• 1:36
  Speaker 1: Do you know how you have a tambourine which is
• 1:38
  Speaker 1: kind of like a round circle the size of your head.
• 1:41
  Speaker 1: I reckon you need to jam one of those around
• 1:43
  Speaker 1: your forehead, in the back of your skull. So he's
• 1:46
  Speaker 1: got at least he's got an auditory target, or at
• 1:51
  Speaker 1: the very least a fucking bell around your Now.
• 1:55
  Speaker 3: He doesn't need it.
• 1:57
  Speaker 1: You can hear everything, certainly wouldn't hurt. Did he hit you?
• 2:01
  Speaker 3: It sure did.
• 2:02
  Speaker 4: Yeah, it goes, It goes, well, it goes.
• 2:05
  Speaker 1: Really the problem, I mean, even if you kind of
• 2:07
  Speaker 1: knew where your head was. David's like, when am I on?
• 2:12
  Speaker 3: No, No, keep going, I've got nothing better to do.
• 2:14
  Speaker 3: Listen to you to bang on about punching blind people.
• 2:21
  Speaker 1: Good point, good point. Hi David, how are you good?
• 2:25
  Speaker 3: How are you?
• 2:26
  Speaker 1: I'm good, I'm good. Well, I did read with interest
• 2:29
  Speaker 1: today that you've got advice for me if in some
• 2:35
  Speaker 1: alternate parallel universe, hypothetical universe, very unlikely universe, where I
• 2:41
  Speaker 1: would be thinking about siren offspring, that you've got some
• 2:46
  Speaker 1: tips for me that might help my chances. You wrote
• 2:49
  Speaker 1: an article which went up on LinkedIn today or yesterday.
• 2:54
  Speaker 3: I don't know.
• 2:55
  Speaker 5: I think I put it up on substack a couple
• 2:57
  Speaker 5: of days ago and then shared it on LinkedIn.
• 2:59
  Speaker 3: Yes, something like that. Yeah, but you.
• 3:02
  Speaker 5: Can see the original over on substack, over on raising
• 3:06
  Speaker 5: Hell on substack, and yeah, that's what the one's one about. Well,
• 3:13
  Speaker 5: it's a couple of different angles. I mean, we've talked
• 3:15
  Speaker 5: before about the vomiting sperm count.
• 3:20
  Speaker 3: I think I'm not sure that we have.
• 3:23
  Speaker 5: Do you remember with the race horse that where they
• 3:26
  Speaker 5: originally started counting sperm, you know, to try and fix
• 3:29
  Speaker 5: that race horses problems and figured out that, oh, you know,
• 3:32
  Speaker 5: this might actually work for humans too. That was back
• 3:35
  Speaker 5: in the nineteen forties. But we've only really been worried
• 3:39
  Speaker 5: about it, probably since the early seventies where people started
• 3:47
  Speaker 5: to really notice that until probably about then, maybe a
• 3:52
  Speaker 5: little bit earlier, but no one was really counting.
• 3:56
  Speaker 3: They were.
• 3:57
  Speaker 5: You could pretty safely say, when a couple lobbed in
• 4:01
  Speaker 5: to the doctors unable to reproduce, unable to conceive, there
• 4:06
  Speaker 5: was a pretty high probability that it was something to
• 4:09
  Speaker 5: do with the female half of the equation, so it
• 4:13
  Speaker 5: was relatively rare, and it often was related to something
• 4:19
  Speaker 5: being wrong with the female's ability to reproduce. And this
• 4:24
  Speaker 5: started to change sort of in the late nineteen sixties
• 4:28
  Speaker 5: nineteen seventies, and it's now more than half of all
• 4:33
  Speaker 5: problems at least are likely to be male oriented. And
• 4:39
  Speaker 5: the problem, it turns out, is plummeting sperm counts. And
• 4:43
  Speaker 5: we've talked about this, as I said before, where we've
• 4:46
  Speaker 5: gone from a situation where even the absolute best producers
• 4:51
  Speaker 5: nowadays well below the worst in the nineteen forties, and
• 4:57
  Speaker 5: when you take averages, average sperm counts have dropped about
• 5:02
  Speaker 5: fifty percent since nineteen seventy three, and the rate is
• 5:07
  Speaker 5: accelerated since two thousand. So it's actually really really starting
• 5:12
  Speaker 5: to be the point where we're not going to have
• 5:16
  Speaker 5: a lot of viable mails left, probably within twenty years.
• 5:22
  Speaker 5: And that's a bit of a concern, but that's not
• 5:27
  Speaker 5: what I really talk about in this piece, which is
• 5:31
  Speaker 5: more focused on what we're doing about it. So obviously
• 5:37
  Speaker 5: a sist of what they call a sist of reproductive
• 5:41
  Speaker 5: technology or ART for short, or what most people call
• 5:44
  Speaker 5: IVF is one of the things that have been done
• 5:49
  Speaker 5: about it, which is that people say, okay, well, and
• 5:54
  Speaker 5: you know, you probably all remember you probably remember reading
• 5:57
  Speaker 5: the paper in nineteen seventy eight when the first IVF
• 6:01
  Speaker 5: or test you baby was born. Yeah, good old Louise Brown,
• 6:08
  Speaker 5: twenty fifth of July nineteen seventy eight.
• 6:11
  Speaker 1: First, I remember, I remember that, and I remember the
• 6:15
  Speaker 1: first heart transplant or the first heart recipient, Fiona Cook.
• 6:21
  Speaker 3: Do you remember, yep, yeah.
• 6:22
  Speaker 1: Because that were two big, big medical things back in
• 6:24
  Speaker 1: the day.
• 6:25
  Speaker 5: Yeah, yeah, Well, this was a very big thing because
• 6:27
  Speaker 5: this was a real solution to female oriented infertility in
• 6:35
  Speaker 5: that what you could do is fertilize the egg outside
• 6:39
  Speaker 5: of the worm, so in a lab introduced the egg
• 6:44
  Speaker 5: to a whole bunch of sperm and get it fertilized
• 6:46
  Speaker 5: and get it underway and then implant it back. And
• 6:50
  Speaker 5: so in vitro fertilization really bypassed pretty much the whole
• 6:58
  Speaker 5: female side of the equation as long as as long
• 7:00
  Speaker 5: as you could because many of the female things, and
• 7:03
  Speaker 5: particularly I think that woman Louise's mother had blocked fillopian
• 7:08
  Speaker 5: tubes or something like that, and so that was a
• 7:10
  Speaker 5: real concern. This bypassed and it solved the problem. So excellent,
• 7:16
  Speaker 5: great advance, great step forward. Trouble is, it didn't help
• 7:20
  Speaker 5: you much if the problem was on the male site,
• 7:22
  Speaker 5: because there was no point introducing male sperm that went
• 7:26
  Speaker 5: up to it, whether they were in vitro or you know,
• 7:30
  Speaker 5: where they should normally be. So it didn't really fix
• 7:34
  Speaker 5: anything from that perspective. So you know, the scientist says
• 7:39
  Speaker 5: they are kept on working on such things, and probably
• 7:44
  Speaker 5: towards the end of the century started coming up with
• 7:49
  Speaker 5: so I think in nineteen ninety one or ninety two
• 7:52
  Speaker 5: was the first commercial use of something called ICSI that's
• 7:57
  Speaker 5: pronounced ixy now.
• 7:59
  Speaker 3: Icsi I.
• 8:02
  Speaker 5: Is where you select one sperm and you inject it
• 8:08
  Speaker 5: directly into the egg.
• 8:12
  Speaker 3: So just one, You pick your favorite and you.
• 8:16
  Speaker 5: Put it straight in there, and none of this competition
• 8:19
  Speaker 5: for the best, biting off the millions of others, none
• 8:22
  Speaker 5: of that sort of rubbish. This is just straight in,
• 8:25
  Speaker 5: guaranteed for at home, home run, okay, And so you
• 8:30
  Speaker 5: would imagine it's probably it significantly solves the issue of well,
• 8:35
  Speaker 5: if you've got a bloke who's either not producing enough
• 8:38
  Speaker 5: or not producing enough that's viable, then that's no big
• 8:42
  Speaker 5: deal because you only need one. So you know, you
• 8:46
  Speaker 5: get out of your microso out and you sort through
• 8:48
  Speaker 5: all the millions that are there and you say, oh,
• 8:50
  Speaker 5: that one looks good, and pick that one out and
• 8:52
  Speaker 5: pop it in. So the problem with that is that
• 9:02
  Speaker 5: you're doing it on the basis of what it looks like.
• 9:04
  Speaker 5: So it's a little bit more than the example I
• 9:08
  Speaker 5: used in the article, which is I said it's like
• 9:10
  Speaker 5: picking the winner of one hundred meter race on the
• 9:12
  Speaker 5: basis of his profile pick. But in essence, that's what
• 9:17
  Speaker 5: you're doing. You're deciding who what is the best most
• 9:23
  Speaker 5: capable sperm to fertilize with on the basis of what
• 9:27
  Speaker 5: it looks like. And no, that doesn't mean they have
• 9:30
  Speaker 5: a mustache and they look pretty much.
• 9:32
  Speaker 3: Oh, it just.
• 9:32
  Speaker 5: Means this one swims well, it doesn't have any shape deformities,
• 9:38
  Speaker 5: it doesn't it doesn't look like there's a problem with it.
• 9:43
  Speaker 5: It looks good to go. So you're looking at those
• 9:47
  Speaker 5: sorts of things. The problem is One of the most
• 9:51
  Speaker 5: dangerous things about introducing sperm is something you can't see.
• 9:58
  Speaker 5: So there's thing called double strand breaks in DNA. So
• 10:04
  Speaker 5: you know, our DNA is two strands, and we're pretty
• 10:07
  Speaker 5: good at repairing errors in our DNA, So we're used
• 10:10
  Speaker 5: to the concept that mutations happen, damage happens, sunlight exposure,
• 10:14
  Speaker 5: radiation exposure, all manner of things can harm DNA, and
• 10:19
  Speaker 5: we're good at fixing it. You know, we've got built
• 10:21
  Speaker 5: in capabilities for fixing it, and in fact, in the
• 10:24
  Speaker 5: eggs there are pretty sophisticated built in capabilities because a
• 10:28
  Speaker 5: woman is born with all the eggs she's ever going
• 10:30
  Speaker 5: to have, so they've got to last a long time,
• 10:33
  Speaker 5: and we're good at repairing them, keeping them up, keeping
• 10:36
  Speaker 5: the DMA viable.
• 10:37
  Speaker 3: Sperm less of a concern.
• 10:39
  Speaker 5: They're not going to last that long anyway, so we
• 10:41
  Speaker 5: have a lot less machinery around it, but we're still
• 10:44
  Speaker 5: pretty good at keeping them going. The problem is that
• 10:48
  Speaker 5: some things can introduce these double strand breaks or DSBs
• 10:52
  Speaker 5: is what they're called, and if that happens, then the
• 10:57
  Speaker 5: sperm can be totally non functional. Now that might be
• 11:01
  Speaker 5: fine if what it does is cause it to just
• 11:03
  Speaker 5: lie there and do nothing. Then they're not going to
• 11:06
  Speaker 5: pick that for ICSI anyway, are they? But sometimes the
• 11:10
  Speaker 5: sperm can look perfectly fine, perfectly healthy, but still contain
• 11:16
  Speaker 5: double strand brakes. And that's a problem because these things
• 11:21
  Speaker 5: turn into or can turn into serious problems in the
• 11:26
  Speaker 5: child that's eventually created. So and I'm talking brain damage,
• 11:31
  Speaker 5: I'm talking childhood cancers, I'm talking autism, all manner of things.
• 11:39
  Speaker 3: In the range of birth defects.
• 11:42
  Speaker 5: It might produce nothing, but it can produce really really
• 11:45
  Speaker 5: bad outcomes if it's not detected. So you don't you
• 11:51
  Speaker 5: want to try and avoid picking the winner and injecting
• 11:56
  Speaker 5: it directly in and having that winner be a sperm
• 12:01
  Speaker 5: that has double strand breaks.
• 12:05
  Speaker 1: So that would almost make that protocol redundant, then, wouldn't it.
• 12:09
  Speaker 1: I mean, because if you can't, like, if you can't
• 12:12
  Speaker 1: tell by looking at it for one of the better term,
• 12:16
  Speaker 1: then it's a gamble. Using that right that it is.
• 12:20
  Speaker 5: A gamble, it is a gamble, but it's a gamble
• 12:22
  Speaker 5: that's got pretty well theoretically has reasonable odds in the
• 12:26
  Speaker 5: sense that this could apply in general, you know, you know,
• 12:31
  Speaker 5: I mean, there's nothing to stop a sperm that has
• 12:34
  Speaker 5: double strand breaks making it all the way through. The
• 12:38
  Speaker 5: problem is that in choosing a winner, you're eliminating a
• 12:42
  Speaker 5: lot of the others that have already been disabled. So
• 12:47
  Speaker 5: you're not letting nature take its course and let you know,
• 12:49
  Speaker 5: ten minion compete for the honor and then the best
• 12:53
  Speaker 5: one gets through. You're just manually going in and saying
• 12:57
  Speaker 5: that one looks good. The problem is that you're significantly
• 13:02
  Speaker 5: increasing the risk of picking one that's got a problem
• 13:06
  Speaker 5: because with other if we were if nature allowed to
• 13:10
  Speaker 5: take its course, then they wouldn't have asked for ICSI
• 13:14
  Speaker 5: in the first place. They would be perfectly happily getting
• 13:17
  Speaker 5: pregnant all on their own without the need for this intervention.
• 13:23
  Speaker 5: So clearly nature is stopping something occurring at that point
• 13:28
  Speaker 5: and preventing it happening, and what ICSI is doing is
• 13:32
  Speaker 5: taking an end run on that and saying, okay, well,
• 13:35
  Speaker 5: you know stuff nature, what would it know, Let's pick
• 13:38
  Speaker 5: the winner and sort it out. It has become an
• 13:44
  Speaker 5: enormously popular procedure in Australia. It's gone from nothing in
• 13:48
  Speaker 5: nineteen ninety two, obviously, because that was when it's just
• 13:50
  Speaker 5: induced to now over sixty percent of all artificial in
• 13:55
  Speaker 5: semina well artificial reproductive technology is used in Australia.
• 14:01
  Speaker 3: It's been a meteoric rise.
• 14:03
  Speaker 5: And that makes sense because this is the only one
• 14:05
  Speaker 5: really that deals with the male side of the problem.
• 14:10
  Speaker 5: So and if the male side of the problem is
• 14:12
  Speaker 5: getting worse and worse and worse, which it is, then
• 14:15
  Speaker 5: you need technologies if you're going to supply that market
• 14:19
  Speaker 5: that deal with the male side. There's no point doing
• 14:21
  Speaker 5: IVF if the problem is on the male side.
• 14:24
  Speaker 1: So so just quickly, right, I know, I know we
• 14:28
  Speaker 1: covered a bit of this a while ago. I just
• 14:32
  Speaker 1: want to I was thinking you said that, So the
• 14:35
  Speaker 1: average sperm production or sperm counters down fifty percent since
• 14:39
  Speaker 1: nineteen seventy three, right, yep, So that's fifty years, give
• 14:43
  Speaker 1: or take. I mean, like even just statistically looking at that,
• 14:51
  Speaker 1: looking at that on a chart would suggest that at
• 14:54
  Speaker 1: some time, some stage in the not too distant future,
• 14:57
  Speaker 1: the males of the species could be producing nothing.
• 15:03
  Speaker 3: Nothing useful, Yes, nothing useful, Like.
• 15:06
  Speaker 1: Based on fifty percent decline in fifty years, I mean
• 15:11
  Speaker 1: that would.
• 15:12
  Speaker 5: Well, and it's accelerated since two thousand. Remember, so the
• 15:14
  Speaker 5: last part of that had the slope has been much
• 15:17
  Speaker 5: much greater. So it's now in Australia estimated to be
• 15:20
  Speaker 5: about dropping about three percent a year in Australia.
• 15:23
  Speaker 1: Is this being spoken about with any level of buckety fuck?
• 15:27
  Speaker 1: We better do something about this?
• 15:29
  Speaker 3: It is by some people.
• 15:32
  Speaker 5: It's particularly important in Israel, for example, which I think
• 15:36
  Speaker 5: has amongst the worst sperm counts in the developed world
• 15:41
  Speaker 5: because of particular dietary peculiarities which will come to They
• 15:46
  Speaker 5: eat an awful lot of seed oil, and seed oil
• 15:50
  Speaker 5: destroys sperm count and also introduces double strand breaks into sperm.
• 15:56
  Speaker 5: So and I guess that brings us around to well, okay,
• 16:01
  Speaker 5: this is all very bad news, But what can you
• 16:03
  Speaker 5: do about it?
• 16:05
  Speaker 3: One of the.
• 16:05
  Speaker 5: Things you can do about it is the things that
• 16:08
  Speaker 5: men were told to do about it in the nineteen seventies,
• 16:12
  Speaker 5: which is they were told if you are planning to conceive,
• 16:16
  Speaker 5: stop drinking and smoking. Now you might say, well, what
• 16:21
  Speaker 5: a drinking and smoking have to do with each other,
• 16:24
  Speaker 5: let alone to do with sperm? And I know, TIFFs,
• 16:30
  Speaker 5: they're you know, barely able to stop herself laughing.
• 16:32
  Speaker 3: But where're you trying to keep it clean? Here? Tiff,
• 16:35
  Speaker 3: all right, the relationship.
• 16:41
  Speaker 1: The things I've never heard in stutter.
• 16:43
  Speaker 3: So much, it's just giggling.
• 16:47
  Speaker 1: Fuck Now.
• 16:51
  Speaker 5: The thing that's in common between smoking and alcohol when
• 16:56
  Speaker 5: it comes to sperm is that both of them produce
• 16:58
  Speaker 5: significant amounts of aldehydes. And we've previously talked about aldehydes
• 17:02
  Speaker 5: and particularly dangerous compounds that destroy DNA. In fact, aldehydes
• 17:08
  Speaker 5: introduce double spram breaks into DNA, and that's why both
• 17:13
  Speaker 5: drinking and alcohol it's recommended you not do a large
• 17:17
  Speaker 5: amount of either if you want to avoid having things
• 17:19
  Speaker 5: like cancer. But this is taking it one step further,
• 17:23
  Speaker 5: which is, if you want to avoid introducing these breaks
• 17:26
  Speaker 5: into your sperm, then you shouldn't be doing that either,
• 17:31
  Speaker 5: because they're particularly susceptible because they are made up largely
• 17:34
  Speaker 5: of poly unsaturated fats, which are particularly amenable to these
• 17:39
  Speaker 5: aldehydes affecting them. So that advice was given to men
• 17:43
  Speaker 5: in the seventies and has been since, which is, if
• 17:47
  Speaker 5: you are planning to conceive, then a good three months beforehand,
• 17:52
  Speaker 5: just give up the booze and the smokes, because that
• 17:54
  Speaker 5: takes the aldehydes out of circulation and it means that
• 17:58
  Speaker 5: you are not going to affect either your fertility or
• 18:02
  Speaker 5: introduce these potential problems of DNA. Now that advice didn't
• 18:07
  Speaker 5: the DNA stuff didn't come with the advice in the
• 18:09
  Speaker 5: nineteen seventies, but certainly the fertility did. What they didn't
• 18:13
  Speaker 5: say because they didn't know it at the time, was
• 18:15
  Speaker 5: you should also stop consuming vegetable oils. You should or
• 18:20
  Speaker 5: what we've referred to a seed oil. So these are
• 18:22
  Speaker 5: the oils that come from canola seeds, sunflower seeds, surflower seeds, soybeans,
• 18:30
  Speaker 5: you know, all that stuff that's generally marketed as vegetable oil,
• 18:34
  Speaker 5: even though vegetables weren't you know, no vegetables were harmed
• 18:38
  Speaker 5: to create it. You can't get oil from a vegetable.
• 18:42
  Speaker 5: They are actually seed oils or legume oils if you
• 18:45
  Speaker 5: want to be more accurate, because you can also get
• 18:46
  Speaker 5: them from soybeans and peanuts and so on. So those
• 18:51
  Speaker 5: things are just as bad as the smoking and the drinking,
• 18:53
  Speaker 5: probably worse because the aldehyde produced by them is even
• 18:58
  Speaker 5: more bioactive than the ones produced by the smoking and
• 19:01
  Speaker 5: the drinking. Once again, we didn't fall off the back
• 19:05
  Speaker 5: of the potato truck yesterday. We do have the ability
• 19:09
  Speaker 5: to deal with these aldehydes. We can deal with them.
• 19:13
  Speaker 5: We can diffuse the damage done by alcohol, we can
• 19:16
  Speaker 5: diffuse the damage done by smoking, and we can diffuse
• 19:19
  Speaker 5: the damage done by seed oils. The trouble is we
• 19:22
  Speaker 5: have limited capacity to do it, and if we overwhelm
• 19:26
  Speaker 5: that capacity by either doing all of those things a lot,
• 19:30
  Speaker 5: or just having a lot of what we eat contain
• 19:36
  Speaker 5: one of them seed oils, then we're in trouble. So
• 19:41
  Speaker 5: we've evolved in an environment where there we're almost no
• 19:44
  Speaker 5: seed oils in our environment because all of our fat
• 19:47
  Speaker 5: came from animals, or if we live near the equator,
• 19:50
  Speaker 5: came from fruit, so things like olive, coconuts, etc. Which
• 19:55
  Speaker 5: are also vegetable oils, but which I have fat profiles
• 19:58
  Speaker 5: very very similar to animal So we evolved in that
• 20:03
  Speaker 5: environment where there just wasn't much seed oil, therefore not
• 20:07
  Speaker 5: a lot of threat from aldehys from seed oil, so
• 20:09
  Speaker 5: our bodies are not attuned so having to deal with
• 20:11
  Speaker 5: vast quantities ofage. But today we live in an environment
• 20:15
  Speaker 5: where everything is cooked in it. Every time you buy
• 20:19
  Speaker 5: anything from a restaurant, from a fast food place, from
• 20:23
  Speaker 5: a supermarket, every single thing has been cooked in those
• 20:28
  Speaker 5: seed oils. So we've gone from an environment where almost
• 20:30
  Speaker 5: none of our food had it to where almost all
• 20:33
  Speaker 5: of it has it.
• 20:34
  Speaker 3: And that's a bad thing when you're.
• 20:36
  Speaker 5: Trying to minimize the effect on a system designed to
• 20:40
  Speaker 5: eliminate those alder hides. So the advice today to a
• 20:45
  Speaker 5: prospective father would be don't smoke, don't drink, and don't
• 20:49
  Speaker 5: eat seed oils if you want to improve a your.
• 20:53
  Speaker 3: Fertility and b your ability to reproduce at all.
• 21:00
  Speaker 1: It's so important that people know that, and I feel
• 21:02
  Speaker 1: like most people don't. I just typed into chatters Whire
• 21:07
  Speaker 1: seed oils called vegetable oils. The term vegetable oil is
• 21:12
  Speaker 1: a broad generic label for oils extracted from plants.
• 21:16
  Speaker 3: I e.
• 21:16
  Speaker 1: Vegetation doesn't mean the oil comes from actual vegetables like
• 21:20
  Speaker 1: broccoli or carrots. Usually comes from seeds, nuts, or fruits
• 21:24
  Speaker 1: of plants. So when you see vegetable oil on a label,
• 21:27
  Speaker 1: it's often a blend of soybean oil, canola oil, rape seed,
• 21:31
  Speaker 1: sunflower oil, corn oil, cottonseed oil, safflower oil, all of
• 21:36
  Speaker 1: which are seeds. Yes, then it says why not just
• 21:39
  Speaker 1: call them seed oils? Good marketing and industrial convenience. Oh
• 21:46
  Speaker 1: that's why for good marketing and industrial convenience, vegetable oil
• 21:50
  Speaker 1: sounds healthy, broad broad, plant based, and neutral. Seed oil
• 21:54
  Speaker 1: sounds more specific. And in recent years it's been given
• 21:58
  Speaker 1: a bad rap by wellness andres people.
• 22:03
  Speaker 5: That's all right, Well, the original source of the name
• 22:07
  Speaker 5: vegetable oil actually was to distinguish it from mineral oil.
• 22:09
  Speaker 5: So if they just called it oil, people would think, oh,
• 22:12
  Speaker 5: what you mean the black stuff we.
• 22:13
  Speaker 3: Dig out of the ground.
• 22:15
  Speaker 5: So there's mineral oil and vegetable oil, meaning you know,
• 22:19
  Speaker 5: stuff we dig out of the ground and stuff that
• 22:21
  Speaker 5: come that got out of plants. So and then it
• 22:25
  Speaker 5: stuck for the reasons that you just read out, which
• 22:27
  Speaker 5: is it's better from a marketing perspective, is it.
• 22:33
  Speaker 1: Is it possible to undo like for people who have
• 22:38
  Speaker 1: had consumed a lot of seed oils historically, if they
• 22:42
  Speaker 1: stop tomorrow, obviously that's better than continuing. But does that
• 22:47
  Speaker 1: undo any of the damage.
• 22:50
  Speaker 5: Well, in this particular case, it's actually one of the
• 22:53
  Speaker 5: few examples where stopping has an immediate effect.
• 22:56
  Speaker 3: Because firm don't last that long.
• 22:59
  Speaker 5: So that's why the advice was to stop smoking and
• 23:04
  Speaker 5: drinking three months before you plan to conceive by then
• 23:08
  Speaker 5: you should have a new batch and it won't be
• 23:11
  Speaker 5: affected at all by what you've been doing before in
• 23:15
  Speaker 5: your life. So in this particular instance, the advice is
• 23:20
  Speaker 5: good because if you stop, and I'd give it six
• 23:23
  Speaker 5: months just to be safe.
• 23:24
  Speaker 3: If you stop and.
• 23:28
  Speaker 5: Not consume those things for six months, then you're making
• 23:32
  Speaker 5: brand new sperm all the time, and those brand new
• 23:35
  Speaker 5: sperm are not going to be affected by aldehydes you
• 23:38
  Speaker 5: consumed six months ago. So in this circumstance, yes, for
• 23:44
  Speaker 5: most things. No, because for most things, what we do
• 23:49
  Speaker 5: is store them as part of the cell membrane in
• 23:51
  Speaker 5: our own bodies. Which is why stopping these things whilst
• 23:55
  Speaker 5: over the longer term will reduce your risk of cancer
• 23:58
  Speaker 5: from consuming them, because you know, slowly the amount in
• 24:01
  Speaker 5: your body decreases. It isn't an instantaneous thing. It's just
• 24:05
  Speaker 5: better to be not consuming them than consuming them. Piece
• 24:11
  Speaker 5: I haven't written yet, and I'll just preface this. We'll
• 24:13
  Speaker 5: talk about it one day, I'm sure, because I really
• 24:15
  Speaker 5: do want to write. This one is the one about
• 24:17
  Speaker 5: how in women, how the fat that we're talking about,
• 24:21
  Speaker 5: the poly unsaturated fact, gets stored in their bottoms and
• 24:25
  Speaker 5: because that's the coolest part of the human body because
• 24:32
  Speaker 5: it's furthest from the central core and so so you know,
• 24:37
  Speaker 5: and why it's stored there is to make baby brains.
• 24:42
  Speaker 5: So the human brain is mostly fat, and so a
• 24:49
  Speaker 5: woman spends most of her life storing up the ingredients
• 24:52
  Speaker 5: for creating a human brain. And where she stores it
• 24:56
  Speaker 5: is in her bottom.
• 25:00
  Speaker 1: That's so funny.
• 25:02
  Speaker 5: It's also it's also why I first born babies are
• 25:05
  Speaker 5: the smartest because they get the benefit of you twenty
• 25:08
  Speaker 5: years worth of storage, whereas the next kid only gets
• 25:11
  Speaker 5: whatever's left over.
• 25:13
  Speaker 1: Oh, so you can say, I want to thank my
• 25:16
  Speaker 1: my My great brain is thanks to my mum and bottom.
• 25:19
  Speaker 3: That's all right, wow, wow, wew.
• 25:23
  Speaker 1: Hi Mary, thanks for only having one kid and making men.
• 25:30
  Speaker 1: What oil do you have in your diet, like I have.
• 25:34
  Speaker 4: A lot of I'm usually olive oil.
• 25:38
  Speaker 3: Yeah, that's a good choice.
• 25:39
  Speaker 5: Yeah yeah, So it's a fruit oil has a profile
• 25:43
  Speaker 5: very very similar to animal fat. So as long as
• 25:46
  Speaker 5: it is actually olive oil. But you never know these days,
• 25:49
  Speaker 5: you know, just because it says it's olive oil on
• 25:50
  Speaker 5: the bottle doesn't mean that's what.
• 25:52
  Speaker 3: They put in the bottle. Really well, there's It depends
• 25:58
  Speaker 3: on it. I mean most strainia manufacturers. Yes it is.
• 26:01
  Speaker 5: If it is olive oil on the bottle, then it
• 26:03
  Speaker 5: is olive oil in it, because it's pretty big penalties
• 26:05
  Speaker 5: for lying about it.
• 26:07
  Speaker 3: But I don't know.
• 26:08
  Speaker 5: Stuff coming from Spain and Lily and so on, I'm
• 26:10
  Speaker 5: not so certain about that.
• 26:12
  Speaker 4: Well, I always buy Australian olive oil.
• 26:15
  Speaker 3: There you go.
• 26:16
  Speaker 1: Is the what's the difference between that and extra virgin?
• 26:21
  Speaker 1: Is it is a label?
• 26:24
  Speaker 3: Oh? Really?
• 26:25
  Speaker 5: Yeah? You know, they have meanings that theoretically matter. From
• 26:34
  Speaker 5: a biochemical perspective, they don't matter at all. There's only
• 26:39
  Speaker 5: really two important types of olive oil. There's refined olive
• 26:43
  Speaker 5: oil and not refined olive oil. So refined olive oil
• 26:47
  Speaker 5: is what is sold in the supermarkets as light olive oil.
• 26:53
  Speaker 5: And I'm not sure why it's light because it's still
• 26:57
  Speaker 5: olive oil. It still has exactly the same number of calories,
• 27:00
  Speaker 5: so I don't know. But it's what makes it light
• 27:04
  Speaker 5: is they've taken all the impurities out of it, so
• 27:06
  Speaker 5: they've filtered out all the dirt and crap that's in
• 27:09
  Speaker 5: normal olive oil, and what that does is give it
• 27:13
  Speaker 5: a higher smoke point. So because there are the things
• 27:16
  Speaker 5: that burn when you burn an oil.
• 27:18
  Speaker 3: So if you.
• 27:19
  Speaker 5: Can cook refined olive oil or light olive oil, you
• 27:23
  Speaker 5: can use it to deep for our chips if you
• 27:24
  Speaker 5: want to.
• 27:25
  Speaker 3: You know, you can go up.
• 27:26
  Speaker 5: Around two hundred and two hundred and ten degrees. But
• 27:30
  Speaker 5: you wouldn't want to do that with an extra virgin
• 27:32
  Speaker 5: olive oil or an unrefined olive oil because it's full
• 27:35
  Speaker 5: of all sorts of impurities which will start to smoke.
• 27:40
  Speaker 1: Oh, give the up, butter cup, and people can find
• 27:42
  Speaker 1: that on substack, David, and also on LinkedIn. Is that correct?
• 27:47
  Speaker 3: Yep?
• 27:49
  Speaker 1: Perfect well, Tiff. If you're looking for a man, and
• 27:53
  Speaker 1: more importantly with your bottom fat that's been getting ready
• 27:57
  Speaker 1: for a baby.
• 27:58
  Speaker 3: Brain.
• 27:59
  Speaker 1: That's that that first baby of yours is just going
• 28:04
  Speaker 1: to be a journeys, isn't it.
• 28:06
  Speaker 2: That's it's a bit unpleasant, un called for. You brought
• 28:11
  Speaker 2: it up, not me, dear h.
• 28:17
  Speaker 1: We'll say goodbye fair but as always, that was fun
• 28:19
  Speaker 1: and we appreciate to doctor Gillespie.
• 28:22
  Speaker 2: See you next time, no worries to see you later.