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Brain Fact: Ozempic · Do You F*cking Mind?

• 0:13
  Speaker 1: Right, the brain fact of today.
• 0:15
  Speaker 2: So this brain fact is going to be short and sweet,
• 0:17
  Speaker 2: but I wanted to cover the topic of ozen Pic
• 0:21
  Speaker 2: also known as semaglue tide, which I'm going to go
• 0:25
  Speaker 2: into in a sect. But basically, ozen Pic is a
• 0:28
  Speaker 2: it's a drug that is used for diabetes to treat diabetes,
• 0:32
  Speaker 2: but has also gained a lot of popularity for where
• 0:36
  Speaker 2: people have been using it for weight loss purposes. And
• 0:38
  Speaker 2: it is even approved in a lot of countries to
• 0:43
  Speaker 2: be prescribed for weight loss. Okay, and I'm going to
• 0:46
  Speaker 2: explain why that is. And I don't know about it.
• 0:49
  Speaker 2: I know that in a lot of countries in the
• 0:50
  Speaker 2: US and Australia for a while there was a shortage
• 0:53
  Speaker 2: of this ozen pic for you know, just in general,
• 0:56
  Speaker 2: and a lot of diabetics were struggling to get a
• 0:58
  Speaker 2: hold of this ozen pic because there was like a
• 1:01
  Speaker 2: surge of popularity for this drug for weight loss purposes.
• 1:04
  Speaker 2: Because apparently I didn't say it, but apparently it was
• 1:06
  Speaker 2: like full trending on TikTok.
• 1:07
  Speaker 1: So let's talk about what it is. What's the deal?
• 1:10
  Speaker 1: So Ozeenpic. It's a brand name for a drug called
• 1:14
  Speaker 1: semaglue tide, and so the generic actual the drug component
• 1:18
  Speaker 1: of it is semiglue tide. And there's other brand names.
• 1:21
  Speaker 1: Ozepic is like the popular one that everyone's been talking about.
• 1:25
  Speaker 1: How does it work for diabetes?
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  Speaker 2: And why is weight loss of side effect? Okay, So
• 1:29
  Speaker 2: basically this is a drug. It's only available by via prescription.
• 1:32
  Speaker 2: It is an injectible drug. You inject it once a
• 1:35
  Speaker 2: week or roughly around that whatever your GP instructs you
• 1:39
  Speaker 2: to do so. And so it's an injectible glucagon like peptide.
• 1:43
  Speaker 2: I'm gonna call it GLP one.
• 1:45
  Speaker 1: We're not just met. That's what it's called.
• 1:46
  Speaker 2: GLP one is the shortened version of glucagon like peptide.
• 1:50
  Speaker 2: It's a receptor agonist. I'll go into that in a second,
• 1:54
  Speaker 2: to help improve glycemic control for people with type two diabetes.
• 1:58
  Speaker 2: So it's turning. When you talk about an agonist, you're
• 2:02
  Speaker 2: basically turning up the function of what is happening at
• 2:05
  Speaker 2: the receptor. So when you talk about an antagonist, you're
• 2:08
  Speaker 2: basically blocking or reversing or kind of doing the opposite
• 2:11
  Speaker 2: of that what.
• 2:12
  Speaker 1: The job of the.
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  Speaker 2: Binding side of that receptor is doing. But here it's
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  Speaker 2: an agonist. Okay, So it's positively enforcing what's going on
• 2:19
  Speaker 2: at that binding site, so receptor agonist to help improve
• 2:23
  Speaker 2: glycemic control for people with type two diabetes. It's turning
• 2:27
  Speaker 2: up the function of what's happening if it is injected subcutaneously,
• 2:31
  Speaker 2: so that means just under the skin, and you can
• 2:33
  Speaker 2: do that either in the thigh, stomach area, or arm.
• 2:36
  Speaker 1: So what is it.
• 2:37
  Speaker 2: GLP is a hormone that we anddogenously produce.
• 2:41
  Speaker 1: It's produced in the body.
• 2:42
  Speaker 2: And it's produced in the gut, and it's released in
• 2:46
  Speaker 2: response to when food is ingested.
• 2:48
  Speaker 1: So when you eat food.
• 2:49
  Speaker 2: Your gut recognizes that and then it releases this hormone
• 2:52
  Speaker 2: called JLP one. It recognizes this gets released, and then
• 2:57
  Speaker 2: it's going to help reduce your appetite because it's it's
• 2:59
  Speaker 2: you notice that foods enter the gut, reduce your appetite.
• 3:04
  Speaker 2: And more importantly, it's going to release insulin or help
• 3:07
  Speaker 2: in releasing insulin, as insulin helps the blood sugar enter
• 3:11
  Speaker 2: the cells of the body, so it can be used
• 3:13
  Speaker 2: as a source of energy or it can be used
• 3:15
  Speaker 2: to store that energy for later. When you take a zepic,
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  Speaker 2: it binds to the receptor of GLP one, which is
• 3:24
  Speaker 2: the naturally produced hormone within your gut, so it binds
• 3:27
  Speaker 2: to the receptor for GLP one and it encourages this
• 3:30
  Speaker 2: insulin release from the pancreas when you need it.
• 3:33
  Speaker 1: So if it's basically getting you to.
• 3:36
  Speaker 2: Release insulin, and that's why it's so important for diabetics, right,
• 3:39
  Speaker 2: and then because of this stimulated insulin release, it's going
• 3:43
  Speaker 2: to help then lower your blood sugar levels. It's going
• 3:46
  Speaker 2: to help reduce the amount of sugar that your liver releases,
• 3:49
  Speaker 2: and it's also going to slow down the rate that
• 3:52
  Speaker 2: food leaves your stomach. And by doing this, it's going
• 3:56
  Speaker 2: to help stop or prevent these spikes in your blood sugar.
• 4:01
  Speaker 2: So really really important for diabetics. Of course, because of
• 4:03
  Speaker 2: that insulin interaction with the body. Side effects of f
• 4:06
  Speaker 2: o zenpic are bloating. There's a whole bunch of side
• 4:09
  Speaker 2: effects and some are really common, some are quite rare,
• 4:12
  Speaker 2: but bloating, gas and stomach discomfort, heartburn, yellow skin and eyes,
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  Speaker 2: that's a little bit rarer, but that is a side effect,
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  Speaker 2: not in every case. Obviously, nausea, vomiting, diarrhea, or constipation,
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  Speaker 2: and in some rare cases, hair loss and also.
• 4:27
  Speaker 1: Loss of taste or change of taste.
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  Speaker 2: And then there are some possible changes to your face
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  Speaker 2: and the fat in your face, because sometimes the fat
• 4:36
  Speaker 2: in your face reduces dramatically, so it causes the skin
• 4:39
  Speaker 2: to look different or loose or whatever, less full. And
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  Speaker 2: then in some rare cases, depending on maybe some other conditions,
• 4:47
  Speaker 2: that the pasian might have kidney damage. But that's not
• 4:51
  Speaker 2: a common side effect.
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  Speaker 1: So why does it cause weight loss?
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  Speaker 2: So basically by its imitating what the natural hormone GLP
• 4:57
  Speaker 2: one does, so it helps create this feeling of full
• 5:00
  Speaker 2: illness and satiety without having to eat.
• 5:03
  Speaker 1: So much food.
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  Speaker 2: And JLP one is normally triggered by so normally you
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  Speaker 2: can create your own release of JLP one.
• 5:10
  Speaker 1: That's the point of it.
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  Speaker 2: By you know, it's triggered by amino acids and peptides
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  Speaker 2: and simple sugars, and this is stuff that you eat
• 5:18
  Speaker 2: in a normal, healthy, balanced diet. So if you're eating
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  Speaker 2: a really healthy, balanced diet with good fats like avocados
• 5:23
  Speaker 2: and nuts, and you know, clean protein sources like eggs
• 5:27
  Speaker 2: or high fiber foods such as veggies, then you get
• 5:29
  Speaker 2: this going to get this good pattern of for release
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  Speaker 2: of JLP one, which is going to make you feel
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  Speaker 2: full or that feeling of society. If you have a
• 5:37
  Speaker 2: diet that's not high in these things, then the release
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  Speaker 2: of JLP one may not be as strong, and therefore
• 5:43
  Speaker 2: you're going to be always searching for more foods.
• 5:45
  Speaker 1: You're gonna feel hungry, you're not gonna feel as satisfied.
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  Speaker 2: So that's why normally you yourself will notice that if you
• 5:50
  Speaker 2: eat a really nutritious meal, you feel more satisfied versus
• 5:54
  Speaker 2: something which is deemed as quote unquote empty calories, which
• 5:57
  Speaker 2: doesn't actually mean anything but this idea of you've eaten,
• 6:01
  Speaker 2: but you don't feel satisfied, so then you want to
• 6:02
  Speaker 2: eat again because whatever, you're not feeling this fullness from
• 6:07
  Speaker 2: that food. So that's what naturally triggers the release or
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  Speaker 2: the creation of GLP one.
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  Speaker 1: So you can just trigger it naturally.
• 6:15
  Speaker 2: However, for a lot of people, especially diabetics, they need
• 6:18
  Speaker 2: to supplement with ozenpic so as you can see, if
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  Speaker 2: it's causing you to feel full, or it's causing you
• 6:24
  Speaker 2: to feel satisfied a lot quicker, then you're by default
• 6:27
  Speaker 2: going to eat less, and that is why it causes
• 6:29
  Speaker 2: weight loss.
• 6:30
  Speaker 1: It just makes you want to eat less.
• 6:32
  Speaker 2: But the issue with that is that, like a lot
• 6:35
  Speaker 2: of weight loss interventions, especially when you look at medication
• 6:38
  Speaker 2: for weight loss, the moment you get off that drug,
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  Speaker 2: it does absolutely fuck all and you you know your
• 6:44
  Speaker 2: weight is back to where it was being on these
• 6:47
  Speaker 2: drugs for weight loss.
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  Speaker 1: It should only be done in what I believe.
• 6:50
  Speaker 2: To be quite serious cases, after you've tried a lot
• 6:53
  Speaker 2: of different things, and it should be obviously done with
• 6:55
  Speaker 2: the guidance of your GP et cetera, et cetera, et cetera.
• 6:58
  Speaker 2: But keep in mind that there are certain people that
• 7:02
  Speaker 2: will take a zenpic and gain weight. Okay, So another
• 7:05
  Speaker 2: side effect of it is that it doesn't actually work
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  Speaker 2: how you want it to work. Like a lot of people,
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  Speaker 2: a lot of drugs will only work in a percentage
• 7:11
  Speaker 2: of the population and not at all, or have the
• 7:13
  Speaker 2: opposite effects with another percentage of the population. And every
• 7:17
  Speaker 2: time ozepic is prescribed, the doctors will enforce quite a
• 7:23
  Speaker 2: well should I should say GPS should be enforcing quite
• 7:27
  Speaker 2: a strict diet and exercise regime to go alongside it.
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  Speaker 2: And this goes for if you're a diabetic as well,
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  Speaker 2: not just if you're taking it for weight loss purposes,
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  Speaker 2: but due to this feeling of fullness whatever, your GP
• 7:38
  Speaker 2: will want you to also stick to quite a healthy
• 7:40
  Speaker 2: diet plan so you're not you know, not eating enough
• 7:43
  Speaker 2: and things like that.
• 7:44
  Speaker 1: So that is the brain fact of today, ozenpic.
• 7:47
  Speaker 2: Hopefully that clarifies why it is that some people have
• 7:50
  Speaker 2: been taking ozepic for weight loss. It is purely an
• 7:53
  Speaker 2: appetite suppressant from a weight loss perspective. It does a
• 7:56
  Speaker 2: lot more for with diabetes, but if it's purely for
• 7:58
  Speaker 2: weight loss, achieving is appetite suppression.
• 8:03
  Speaker 1: So I feel like.
• 8:04
  Speaker 2: Anyway, not gonna give my advice, I've got my thoughts
• 8:07
  Speaker 2: and opinions, but basically like, yeah, if you don't have
• 8:09
  Speaker 2: to take it, absolutely do.
• 8:10
  Speaker 1: Not fucking take it. Is basically how I feel about it. Cool,
• 8:14
  Speaker 1: that is the brain fact of today.