Pharma 19: Hypnotics and Sedatives - Calming the Overactive Brain
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This episode explores hypnotics and sedatives as agents that lower arousal thresholds rather than induce unconsciousness. We examine how these drugs interact with inhibitory systems—particularly GABAergic signalling—to quiet hyperactive networks, facilitate sleep, and reduce anxiety. Framed this way, their benefits and risks become predictable: sedation…
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