Latest / Morning Medical with Dr. Chow / Chronic Pain Breakthrough, Ontario Drug Site Closure, and New COVID Variant BA.3.2
Transcript
- 0:00Welcome to Morning Medical with Dr.
- 0:02Chow.
- 0:03I'm your host, Dr.
- 0:04Chi-Ming Chow.
- 0:06Today, we're diving into some fascinating developments in the world of health and
- 0:10medicine, starting with a promising breakthrough in the treatment of chronic back
- 0:14pain.
- 0:18Chronic back pain is a condition that affects millions of people worldwide, often leading to
- 0:24a significant reduction in quality of life.
- 0:27Traditional treatments have focused on managing symptoms rather than addressing the root cause,
- 0:32but new research suggests that this might be about to change.
- 0:37A recent study led by Dr.
- 0:39Janet L.
- 0:40Crane at Johns Hopkins University has found that a hormone commonly used for treating bone
- 0:46loss, known as parathyroid hormone, could be key to addressing chronic back pain at its
- 0:52source.
- 0:53This hormone is naturally produced by the parathyroid glands and plays a crucial role in
- 0:58regulating calcium levels and bone remodeling.
- 1:02In cases of spinal degeneration, pain-sensing nerves often grow into areas of the spine where
- 1:08they normally wouldn't be, causing discomfort and pain.
- 1:12Dr.
- 1:13Crane's research indicates that parathyroid hormone can reverse this nerve growth by
- 1:18activating natural signals that repel these nerves from sensitive areas.
- 1:23The study utilized animal models and found that after one to two months of parathyroid hormone
- 1:29treatment, the vertebral endplates became denser and more stable.
- 1:35This effect was attributed to the hormone's ability to stimulate bone-building cells, known
- 1:40as osteoblasts, to produce a protein called Slit3.
- 1:44This protein appears to play a critical role in preventing nerve infiltration into the spine.
- 1:50Interestingly, patients who have been receiving synthetic versions of parathyroid hormone for
- 1:55osteoporosis have reported unexpected relief from back pain, which this study helps to
- 2:01explain.
- 2:03The findings suggest that parathyroid hormone could shift the focus of back pain treatment
- 2:08from symptom management to addressing the underlying pathology.
- 2:12While the results are promising, researchers caution that further studies, including
- 2:17clinical trials, are necessary to fully explore the hormone's potential as a treatment for
- 2:22spinal degeneration.
- 2:24They also note that the study focused primarily on the Slit3 protein, and more research is
- 2:30needed to understand how other genetic and physiological factors might influence the
- 2:34treatment's effectiveness.
- 2:37This study was published in the journal Bone Research and offers a hopeful outlook for those
- 2:42suffering from chronic back pain.
- 2:45As always, we'll keep you updated on any further developments in this area.
- 2:51Ontario Premier Doug Ford and Health Minister Sylvia Jones have made it clear that their
- 2:56decision to close more supervised drug consumption sites will stand firm, despite
- 3:01calls from prominent figures to reconsider.
- 3:04Six former mayors of Toronto have recently penned a letter urging the provincial
- 3:08government to reverse the closures, which have sparked significant debate and concern within
- 3:13the community.
- 3:15Just two weeks ago, the province announced that it would be withdrawing funding from seven
- 3:20supervised consumption sites, with closures expected by mid-June.
- 3:25This decision follows the previous year's shutdown of nine other sites, which the
- 3:30government determined were too close to schools and daycares, raising concerns about safety.
- 3:35Premier Ford, speaking at a news conference, emphasized his intent to prioritize community
- 3:41safety, citing the presence of needles in public spaces as a danger to children and
- 3:46families.
- 3:48"I want to help these people, but I'm not going to sit back as you put these injection sites in
- 3:53the middle of communities," Ford stated.
- 3:56Health Minister Sylvia Jones reiterated the government's stance, highlighting a shift
- 4:00towards what she described as an abstinence-based model known as homelessness
- 4:04and addiction recovery treatment, or HART, hubs.
- 4:08"We're not going to reverse," Jones said, underscoring the commitment to providing
- 4:12treatment pathways rather than supporting what she referred to as the use of illicit drugs.
- 4:18The province has already funded 28 new HART hubs, with nearly all operational, as part of
- 4:26their strategy to transition away from supervised consumption sites.
- 4:31However, this decision has not been without criticism.
- 4:34Health-care workers, advocates, and even six former mayors have expressed deep concerns,
- 4:41warning that the closures could lead to increased drug use and related deaths.
- 4:46The former mayors, including notable figures like David Crombie and John Tory, argue that
- 4:52the closures have already resulted in significant harm, pointing to an 82 percent
- 4:57increase in non-fatal opioid overdose calls in Toronto following the initial site closures.
- 5:03They assert that the decision lacks the desired positive impacts and has led to increased
- 5:08public expenditures.
- 5:10Data from Toronto Paramedic Services supports these concerns, showing a significant rise in
- 5:15opioid overdose calls since the closures began.
- 5:19While the province had seen a downward trend in such incidents from 2023 to early 2025, the
- 5:25recent statistics suggest a troubling reversal.
- 5:29The New Democratic Party leader, Marit Stiles, criticized the government's approach, calling
- 5:34for decisions to be guided by empathy and evidence.
- 5:38She warned that removing essential services without adequate replacements could exacerbate
- 5:43the problem rather than solve it.
- 5:46Meanwhile, the Liberal Party has proposed a compromise, suggesting that supervised
- 5:51consumption sites could still play a role if integrated within hospitals or community
- 5:56clinics.
- 5:58Lee Fairclough, the Liberal mental health critic, emphasized harm reduction as an
- 6:03evidence-based approach that should not be overlooked.
- 6:07As this debate unfolds, the impact of these closures on public health and safety continues
- 6:12to be a topic of intense scrutiny, with many advocating for a balanced approach that
- 6:17addresses both community concerns and the needs of those struggling with addiction.
- 6:24A new variant of COVID-19, known as BA.3.2, is spreading across the United States, according
- 6:32to health officials.
- 6:33This variant has been reported in at least twenty-three countries as of February eleventh,
- 6:39based on a study published last week by the Centers for Disease Control and Prevention.
- 6:45The BA.3.2 variant has approximately seventy to seventy-five changes in the gene sequence of
- 6:51its spike protein, which is a structure on the surface of the COVID-19 virus that helps it
- 6:58enter human cells.
- 7:00The Centers for Disease Control and Prevention has been closely monitoring this variant
- 7:05through its Traveler-Based Genomic Surveillance program.
- 7:08It has been detected in nasal swabs from four travelers in the United States, clinical
- 7:13samples from five patients, three airplane wastewater samples, and one hundred thirty-two
- 7:19wastewater surveillance samples from twenty-five states, according to the Centers
- 7:23for Disease Control and Prevention's Morbidity and Mortality Weekly Report.
- 7:30The BA.3.2 variant began to rise in prevalence in September 2025 and was first confirmed in
- 7:37the United States in June 2025 in a person traveling from the Netherlands.
- 7:42The weekly detections of this variant increased to about thirty percent of cases identified in
- 7:47Denmark, Germany, and the Netherlands from November 2025 to January 2026.
- 7:54One of the concerning characteristics of the BA.3.2 variant is its 'immune escape'
- 8:01capability.
- 8:02This means it has mutations that may help it partially evade existing immunity from vaccines
- 8:08or previous infections.
- 8:10While this could make infections more likely, experts suggest it does not necessarily lead to
- 8:15more severe illness.
- 8:17The study authors noted that BA.3.2 represents a new lineage of SARS-CoV-2, genetically
- 8:25distinct from the previous lineages that have circulated in the United States since January
- 8:292024.
- 8:31The prevalence of this new variant might be even larger than current data suggests, as many
- 8:36countries have limited genomic detection and surveillance capabilities.
- 8:41Phylogenetic analyses have identified the emergence of two sublineages, BA.3.2.1 and
- 8:48BA.3.2.2, indicating ongoing viral evolution.
- 8:54The researchers emphasize the need for continuous genomic surveillance to monitor the
- 8:58virus's evolution and assess its potential impact on public health.
- 9:03With the BA.3.2 mutations in the spike protein potentially weakening the protection from
- 9:09vaccination or prior infection, the Centers for Disease Control and Prevention is urging
- 9:15ongoing genomic surveillance to track the virus's evolution and evaluate its impact on
- 9:21public health.
- 9:24In Cuba, health-care workers are currently facing unprecedented challenges due to a United
- 9:30States oil embargo that began in January.
- 9:33This embargo has caused significant fuel shortages, skyrocketing food prices, and
- 9:39widespread power outages across the country.
- 9:42The situation is particularly dire for those working at Havana's Cardiology Institute, where
- 9:47young health-care providers are feeling the strain both in their professional and personal
- 9:51lives.
- 9:53Jose Carlos, a thirty-one-year-old cardiology resident, shared his perspective on the current
- 9:59crisis.
- 10:00He described it as the most difficult period of his life.
- 10:04"Since I was born, this is the most difficult time, without any doubt," he told CBC News.
- 10:11The combination of energy shortages, lack of resources, and transportation issues has made
- 10:17providing life-saving care extremely challenging.
- 10:21Cuba has long been recognized for the quality of its health care system, often sending
- 10:25medical teams abroad to assist other countries.
- 10:29However, the ongoing embargo has severely impacted the national health system.
- 10:35This includes delays in surgeries, medication shortages, and a lack of essential equipment
- 10:41like pacemakers.
- 10:43The situation is reportedly worse outside of Havana, where rural areas struggle even more
- 10:49without adequate supplies and longer-lasting blackouts.
- 10:54The embargo has also made daily life exceedingly difficult for health-care workers.
- 10:59Public transportation has been crippled by fuel shortages, making it hard for workers to even
- 11:05get to their jobs.
- 11:06Jose Carlos mentioned that doctors' salaries, which are less than forty Canadian dollars a
- 11:11month, are insufficient to cope with the rising cost of food and basic necessities.
- 11:17Despite these challenges, many health-care workers remain committed to their roles.
- 11:22Jose Carlos, for instance, is determined to stay in Cuba because his family is there.
- 11:27Others, like Pablo, a twenty-seven-year-old cardiology resident, are contemplating leaving
- 11:32the country in search of better opportunities.
- 11:35Pablo expressed interest in working in countries like Spain, Italy, or even Canada,
- 11:41citing concerns about the future under the current U.S.
- 11:43administration and the Cuban government.
- 11:46The situation has led to significant delays in critical procedures, such as stent placements,
- 11:52which can now take one to three months.
- 11:55These delays are compounded by the lack of resources and the transportation issues
- 11:59affecting the delivery of medical supplies.
- 12:03Dr.
- 12:04Julio Cesar Rodriguez Cardona, a municipal general director of health in Havana,
- 12:10highlighted the severe impact on patient transport, supply chains, and food availability
- 12:15in hospitals.
- 12:17The embargo's effect on electricity generation is another major concern.
- 12:22With regular blackouts, maintaining vital services like intensive care units becomes
- 12:28extremely challenging.
- 12:30Dr.
- 12:31Rodriguez Cardona noted the terrifying prospect of an intensive care room unable to keep
- 12:37essential equipment running due to power failures.
- 12:40The dedication of Cuban health-care workers is evident as they continue to serve their
- 12:46patients despite these overwhelming obstacles.
- 12:49Iriana, a twenty-four-year-old lab technician, mentioned that many patients consider them
- 12:55heroes.
- 12:56However, she also pointed out that the rising cost of living is forcing some of her
- 13:01colleagues to leave the profession in search of better-paying jobs.
- 13:05As Cuba struggles with the compounded effects of the U.S.
- 13:09oil embargo and its own economic challenges, the resilience and commitment of its
- 13:13health-care workers remain a beacon of hope for many Cubans.
- 13:16The situation underscores the need for international dialogue and support to alleviate
- 13:21the hardships faced by these dedicated professionals and the patients they serve.
- 13:28A recent landmark trial in the United States has resulted in a jury finding both Meta and
- 13:33YouTube liable for contributing to social media addiction, marking a significant precedent in
- 13:39legal accountability for tech giants.
- 13:42This case, the first of its kind, was brought forward by a twenty-year-old woman who
- 13:47testified that her early and excessive use of social media platforms exacerbated her mental
- 13:53health issues.
- 13:55The trial spanned over a month, with jurors deliberating for more than forty hours across
- 14:01nine days.
- 14:03This decision highlights the growing concerns around the impact of social media on mental
- 14:07health, particularly among younger users.
- 14:11The plaintiff argued that the addictive nature of these platforms played a substantial role in
- 14:16her mental health struggles, which she has been battling since her teenage years.
- 14:21This case reflects a broader societal debate on the role of social media in our lives and its
- 14:27potential health implications.
- 14:29Critics argue that platforms like Meta and YouTube have designed their services to
- 14:34maximize user engagement, often at the expense of users' well-being.
- 14:39The addictive features, such as endless scrolling and personalized content, are under
- 14:45scrutiny for their psychological effects.
- 14:49The implications of this ruling could be far-reaching, potentially opening the door for
- 14:54more lawsuits against social media companies.
- 14:57It also raises questions about the responsibility these platforms have in
- 15:02safeguarding the mental health of their users.
- 15:05With mental health issues on the rise globally, this trial emphasizes the need for a balanced
- 15:10approach that considers both technological innovation and user safety.
- 15:16As we conclude today's episode, it's clear that the intersection of technology and health
- 15:21continues to present both challenges and opportunities.
- 15:26From groundbreaking research in treating chronic back pain to the ongoing debate over
- 15:30supervised consumption sites, and now this pivotal legal case, the landscape of health and
- 15:36medicine is ever-evolving.
- 15:39Thank you for joining us on this episode of Morning Medical with Dr.
- 15:42Chow.
- 15:43We look forward to bringing you more updates and insights on the latest in health and
- 15:48medicine.
- 15:48Until next time, stay informed and take care.