Targeting PLA2G15 Reduces Senescence and Alters Lipid Metabolism in Kidney Cells
BUFFALO, NY — October 13, 2026 — A new #research paper was #published in Volume 18 of Aging on September 16, 2026, titled “Targeting phospholipase Pla2g15 reduces long-chain BMP phospholipids abundance and senescence in kidney cells.” The study found that disrupting the gene Pla2g15 reduced stress-induced cellular senescence in mouse kidney cells while altering the composition of phospholipids involved in lysosomal function. The findings identify a possible connection between lipid metabolism, mitochondrial pathways and kidney aging, suggesting that PLA2G15 could become a potential…
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