Latest / Morning Medical with Dr. Chow / Senator Bernie Sanders on Wegovy Costs, Canada's Screening Guidelines, and Bird Flu Outbreak
Transcript
- 0:00Good morning, and welcome to another episode of Morning Medical with Doctor Chiao.
- 0:04I am your host, Doctor Chi-Ming Chiao.
- 0:07As always, we bring you the latest and most important medical and health news from around
- 0:11the world using the power of artificial intelligence to keep you informed and healthy.
- 0:18Today, we have a packed docket with stories ranging from groundbreaking treatments for
- 0:23kidney disease.
- 0:24To the potential economic impacts of weight loss medications and even the role of
- 0:29artificial intelligence in answering your health questions.
- 0:33So let's get started.
- 0:37In today's first segment, we will be discussing some very promising news about medications that
- 0:42many of you may have already heard of ozempic and Wigovey.
- 0:46These medications, known primarily for their use in managing type 2 diabetes and aiding in
- 0:52weight loss, could have another significant benefit.
- 0:55A recent study suggests that they may also be effective in treating chronic kidney disease.
- 1:01This study led by researchers from the University of New South Wales in Sydney,
- 1:05Australia was conducted between June 2019 May 2021.
- 1:11It included over 3500 participants from 28 countries who were suffering from both type 2
- 1:18diabetes.
- 1:19And chronic kidney disease.
- 1:21What makes this study particularly interesting is the dosage used.
- 1:26The participants were given a small weekly dose of semaglutide, the active ingredient in both
- 1:32Ozempic and Wagavi.
- 1:34Just 1.0 milligrams per week.
- 1:37This is notably less than what is typically prescribed for weight loss or diabetes
- 1:41management.
- 1:43The results were quite remarkable.
- 1:46Over a median follow-up period of 3.4 years, the researchers found that this small dose of
- 1:52semaglutide reduced the likelihood of major kidney events by 24%.
- 1:58In addition to its renal benefits, the medication also showed cardiovascular
- 2:02advantages.
- 2:04Participants were 18% less likely to experience a heart attack, stroke, or other cardiovascular
- 2:10events while on semaglutide.
- 2:13So why does semaglutide have such a beneficial effect?
- 2:16According to doctor Brett Osborne, a neurologist and longevity expert in Florida who
- 2:22was not involved in the study, The medication works by improving glycemic control, which is
- 2:28crucial for managing diabetic nephropathy or kidney disease caused by diabetes.
- 2:34Additionally, semaglutide lowers inflammation, particularly within the blood vessel lining,
- 2:41which reduces blood vessel damage, and improves blood flow through the kidneys.
- 2:46This combination of effects offers substantial renal and cardiovascular protection for
- 2:50patients with type 2 diabetes and chronic kidney disease.
- 2:55Doctor Mark Siegel, a clinical professor of medicine at NYU Langoni Medical Center, and a
- 3:02Fox News medical contributor also weighed in on the study.
- 3:06He described the findings as very important.
- 3:09And highlighted that the metabolic effects of semaglutide help reduce inflammation, overcome
- 3:15insulin resistance, and improve insulin function and glucose metabolism at the cellular
- 3:21level.
- 3:22According to doctor Siegel, These benefits could have broader implications for all
- 3:27patients with kidney failure or those at risk for it.
- 3:31The study findings were announced at the European Renal Association Congress in Sweden
- 3:37and Novo Nordisk, the Denmark based company that makes Ozempic and Wengovi has been
- 3:43enthusiastic about the results.
- 3:45Michael Raidan, the executive medical director for diabetes at Novo Nordisk, stated that this
- 3:51study highlights their drive to make a meaningful difference in the lives of people
- 3:56living with type 2 diabetes and chronic kidney disease.
- 3:59However, for this potential treatment to become widely available, there are still hurdles to
- 4:05overcome such as supply shortages, and the need for regulatory approval.
- 4:15Of getting these results into clinical practice.
- 4:19He noted that the challenge lies in making the drug accessible to those who would benefit from
- 4:24it.
- 4:24Those who would potentially live longer without the need for dialysis, heart attacks, or
- 4:29strokes if they take this medication.
- 4:32This study not only opens up new avenues for treating chronic kidney disease, but also
- 4:36underscores the broader potential of semaglutide and improving human health.
- 4:42That wraps up our first segment for today.
- 4:45Stay tuned as we pivot to our next topic where we will discuss the economic implications of
- 4:50wide spread use of Wagavi in the United States.
- 4:54You will not want to miss it.
- 4:56In this next segment, we turn our focus to the economic implications of WEgovy, a medication
- 5:02that has been making headlines for its effectiveness in weight loss.
- 5:07However, It is not all good news.
- 5:09According to a new report by Senator Bernie Sanders, widespread use of Wigoby could have
- 5:14dire financial consequences for the United States health system.
- 5:19The report, which was released earlier this week, highlights the potential risks associated
- 5:23with the high cost of Wegave, Wiegavi, also known by its generic name Samaglutide, is
- 5:29produced by the Danish pharmaceutical company, Novo Nordisk, It is the same active ingredient
- 5:35found in Ozempic, but Wagavi is specifically dosed and marketed for weight loss.
- 5:40While its effectiveness in helping people lose weight has been widely praised, the cost of the
- 5:45medication is raising significant concerns.
- 5:49According to Sanders's report, the list price for Wagavi is approximately $300 per month.
- 5:56This is substantially higher than many other weight loss medications currently available on
- 6:01the market.
- 6:02Sanders argues that if even fraction of the estimated 100,000,000 Americans who are obese,
- 6:08where to begin using WEGovy, the financial burden on the health system would be
- 6:12unsustainable.
- 6:14He points out that the cost could potentially run into the 100 of 1,000,000,000 of dollars
- 6:18annually, which would strain both public and private health insurance programs.
- 6:24Senator Sanders has long been an advocate for more affordable health care and prescription
- 6:28drug prices.
- 6:30In his report, he calls for immediate action to address the high cost of Wagavi.
- 6:35Sanders suggests that Novo Nordisk should lower the price of the medication to make it more
- 6:40accessible to the millions of Americans who could benefit from it.
- 6:46He also urges the United States government to consider measures such as price negotiations
- 6:51and importation of cheaper drugs from other countries to alleviate financial strain.
- 6:57However, not everyone agrees with Sanders' assessment.
- 7:01Some experts argue that the long term health benefits of weight loss medications like Wagavi
- 7:07could offset the initial high costs.
- 7:11Doctor Caroline Opovian a professor of medicine at Harvard Medical School and co director of
- 7:16the Center for Wait Management And Wellness at Brigham And Women's Hospital, believes that
- 7:21investing in effective weight loss treatments could ultimately reduce health care costs in
- 7:25the long run.
- 7:27She points out that obesity is a major risk factor for a multitude of chronic conditions,
- 7:33including type 2 diabetes, cardiovascular disease, and certain types of cancer.
- 7:39By addressing obesity, we could potentially lower the incidence and severity of these
- 7:44conditions, thereby reducing overall health care expenditures.
- 7:49Meanwhile, Novo Nordisk has responded to the report by emphasizing the value that Wengavi
- 7:54provides.
- 7:55In a statement, the company highlighted the clinical benefits of the medication, noting
- 8:01that it has been shown to help patients lose a significant amount of weight and improve their
- 8:06overall health.
- 8:08Novo Nordisk also pointed out that they offer patient assistance programs to help those who
- 8:13may not be able to afford the medication at its list price.
- 8:18The debate over the cost of Wengoby is likely to continue as more people seek effective
- 8:23treatments for obesity.
- 8:25While the financial implications are a serious concern, It is clear that there is also a
- 8:30pressing need for effective weight management solutions.
- 8:33As with many issues in health care, Finding a balance between cost and benefit will be key to
- 8:39addressing this challenge.
- 8:41That concludes this segment on the economic implications of Gregory.
- 8:45Stay with us as we move on to our next topic.
- 8:48Why Canada is not lowering its breast cancer screening guidelines to 40 despite expert
- 8:54pushback?
- 8:55You will want to hear this.
- 8:58Canada's guidelines for routine breast cancer screenings will remain unchanged despite
- 9:03mounting pressure from medical experts who have labeled them as dangerous.
- 9:07The Canadian task force on preventive health care released its updated guidelines Thursday,
- 9:12recommending that people in their forties should not get routine mammograms, but can
- 9:17request 1 if they want.
- 9:19The current guidelines set by the task force are to begin routine breast cancer screening at
- 9:24age fifty.
- 9:26Doctor Ike Miller, a family physician, and member of the Canadian task force on preventive
- 9:32health care emphasized that the first and most important recommendation coming out of this
- 9:38guideline is that breast cancer screening is a personal choice and that people deserve
- 9:43information so that they can make the right choice for them.
- 9:47She stated during a media briefing on Thursday, we recommend that women between the ages of 40
- 9:5374 are provided with information about the benefits and harms of screening to make a
- 9:59decision that aligns with their values and preferences.
- 10:03Doctor Miller added that this information should cover factors like family history, race,
- 10:09or ethnicity, and breast density.
- 10:12If someone is aware of these factors and wishes to be screened, they should be offered
- 10:17mammography every 2 to 3 years.
- 10:21The task force said it holds firm on its position not to lower the recommended age due
- 10:25to concerns of overdiagnosis and unnecessary biopsies.
- 10:30However, the new breast screening guidelines released today by the Canadian task force on
- 10:35preventive health care are being described as dangerous and harmful to Canadians, according
- 10:41to Jenny Dale, executive director of dense breast Canada.
- 10:46In an email to global news, Dale expressed disappointment in the recommendations stating
- 10:52the guidelines should reflect the latest evidence and prioritize spend these guidelines
- 11:03and use modern science to save lives.
- 11:07Doctor S Paula Goran, a Vancouver based radiologist, shared similar concerns.
- 11:12She stated there is good evidence that when breast cancers are detected earlier through
- 11:17screening, there is less need for harsh debilitating treatments such as mastectomy,
- 11:22ancillary dissection, and chemotherapy.
- 11:26Doctor Goran added that she is deeply concerned that Canadians will continue to face
- 11:30unnecessary later stage breast cancer because of these guidelines.
- 11:36The news comes more than a month after the Canadian task force was urged by many medical
- 11:41professionals to lower the current guidelines for breast cancer screening from 50 to 40,
- 11:47calling them outdated and flawed.
- 11:50Speaking at a media conference on April 15th, Doctor Martin Yaffe, the co director of the
- 11:56Imaging Research Program at the Ontario Institute for Cancer Research.
- 12:00Warned that the problem is that women and their doctors are receiving dangerous guidance on
- 12:06breast cancer screening from the Canadian task force preventive health care.
- 12:11He emphasized that much of the death and suffering could have been avoided if Canadian
- 12:15screening guidelines had been based on modern scientific evidence.
- 12:20The Canadian Cancer Society also expressed disappointment by the new breast screening
- 12:25guidelines specifically the lack of a recommendation to lower the start age to
- 12:31systematically screen for breast cancer nationwide.
- 12:35On May 9th, the Canadian Cancer Society released a statement urging all provinces and
- 12:41territories to begin breast cancer screening at age forty for those at average risk of the
- 12:45disease.
- 12:47Despite the recommendations of the task force, it is ultimately the provinces and territories
- 12:53that decide when screening should begin.
- 12:56Many have already lowered the beginning age to forty.
- 12:59For instance, Ontario announced in October 2023 that it would be lowering the starting age for
- 13:06screenings to 40.
- 13:08While British Columbia, Nova Scotia, Prince Edward Island, and the Yukon have had the
- 13:14starting age at 40 for decades.
- 13:18New Brunswick recently changed its beginning age to 40 for screenings.
- 13:23Additionally, a United States task force recently changed its recommendations to age
- 13:28forty.
- 13:29Sherry Wilcox, a forty six year old lawyer from Toronto, and a breast cancer survivor,
- 13:35expressed disappointment over the task force's decision not to lower the screening age to 40.
- 13:41Wilcox shared her personal story explaining that despite her insistence at age forty, her
- 13:47doctor advised against it.
- 13:50I was told by my then family physician that because I had no family history and because I
- 13:55hadn't yet reached the age of fifty, it just didn't make any sense.
- 13:59She told global news.
- 14:024 years later, she felt a lump on her breast.
- 14:04And after pushing for another mammogram and then a biopsy, She was diagnosed with an
- 14:09aggressive form of breast cancer.
- 14:12Wilcox underwent a double mastectomy, radiation, and chemotherapy.
- 14:17She is now cancer free, but remains concerned that her aggressive cancer could return at any
- 14:22time.
- 14:23Because of her experience, Wilcox wants Canadians to be aware of their right to request
- 14:29a mammogram.
- 14:31She firmly believes that had she received 1 at 40, her cancer might have been less aggressive
- 14:37or she may have needed less treatment.
- 14:40Wilcox believes that placing the burden on patients to request a breast screening from
- 14:44their doctor is harmful.
- 14:47Doctors are busy.
- 14:48And when the task force says it's not recommended for women age forty to forty nine,
- 14:53That'll be what doctors rest their eyes on, she said.
- 14:57There are a lot of women out there who will have trouble convincing their physicians that
- 15:00screening is for them and people trust their physicians.
- 15:04Positions are in a position of power.
- 15:07Wilcox said the task forces decision will result in more women being denied early
- 15:12screening, leading to later detection of more advanced cancers and subjecting them to more
- 15:18chemotherapy, radiation, and aggressive surgeries.
- 15:22These mammograms can catch cancer years before they can be felt.
- 15:26This is not news.
- 15:27It's not controversial, she said.
- 15:30Google has recently launched a new feature called AI, overviews that uses generative
- 15:36artificial intelligence.
- 15:37A type of machine learning technology trained on information from across the internet.
- 15:43This feature produces conversational answers to some search questions in a matter of seconds.
- 15:49While this may sound promising, it has raised eyebrows particularly when it comes to
- 15:54answering health related questions.
- 15:57In the weeks since AI overviews was introduced, users have encountered a wide array of
- 16:04inaccuracies and odd answers on various subject However, the stakes are particularly high when
- 16:11it comes to health questions, while the technology could potentially guide people
- 16:16toward healthier habits or necessary medical care, it also has the potential to provide
- 16:21inaccurate information.
- 16:23This is especially concerning because the AI can sometimes fabricate facts.
- 16:28If its answers are influenced by websites that are not grounded in science, it might offer
- 16:33advice that contra medical guidance or even poses a risk to one's health.
- 16:40For instance, the system has already been shown to produce bad answers seemingly based on
- 16:45flawed sources.
- 16:47When asked, how many rocks should I eat?
- 16:50AI.
- 16:52Overviews told some users to eat at least one rock a day for vitamins and minerals.
- 16:58This erroneous advice was scraped from the onion, a satirical website.
- 17:03Such incidents highlight the critical importance of scrutinizing the sources of
- 17:07information.
- 17:08Especially in health related contexts.
- 17:12Doctor Karen Deep Singh, chief health artificial intelligence officer at University
- 17:16of California San Diego Health, Emphasize that you cannot trust everything you read.
- 17:21In health, the source of your information is essential.
- 17:26This sentiment underscores the risks associated with relying on AI generated health advice
- 17:31without adequate verification.
- 17:34Chi-Ming Boudaraju, a Google senior director of product management, who helps lead work on AI
- 17:41overview.
- 17:42Stated that health searches had additional guardrails, but she declined to describe those
- 17:47in detail.
- 17:48She mentioned that searches deemed dangerous or explicit or that indicates someone is in a
- 17:53vulnerable situation, such as with self harm, do not trigger ai Ching, summaries.
- 18:00However, the lack of transparency about these guardrails raises further questions about the
- 18:05reliability and safety of the information provided.
- 18:09Take the question.
- 18:10Is chocolate healthy?
- 18:12Google's AI generated answer pulls up information from research on heart health,
- 18:16mental health, and more.
- 18:19The search results page lists health benefits, including inflammation and heart health of
- 18:24eating chocolate.
- 18:26Answers to health questions like this often draw from reputable sources.
- 18:30For example, 3 search result boxes show articles published in sources like Johns
- 18:35Hopkins Medicine and medical news today.
- 18:38However, in this case, the response also cites VINCI, an Italian chocolate and gelato company,
- 18:43and an article titled is dark chocolate good for weight loss.
- 18:48A similar search is chocolate healthy for you.
- 18:51Generated an answer from sources including the website of a company called Zoey, which sells
- 18:58at home gut intelligence tests, and a nutritional app.
- 19:02This example illustrates how commercial interests can sometimes infiltrate AI generated
- 19:08health advice potentially skewing the information provided to users.
- 19:14The introduction of AI overviews by Google Certainly marks a significant development in
- 19:19the use of artificial intelligence for disseminating health information.
- 19:24However, it also underscores the necessity for critical evaluation of the sources behind the
- 19:29information.
- 19:30While the technology holds promise, it is not without its pitfalls and users should remain
- 19:36cautious and seek verification from trusted medical professionals when it comes to health
- 19:41related advice.
- 19:43In our final segment today, we turn our attention to a concerning development in the
- 19:47United States involving bird flu.
- 19:50A third farmworker has been found to be infected with the H5N1 strain of bird flu,
- 19:56raising alarms about a potential outbreak among dairy cattle.
- 20:00This latest case is particularly worrisome because the worker has exhibited respiratory
- 20:06symptoms, including a cough, sore throat, and watery eyes.
- 20:10These symptoms generally increase the likelihood of transmission to other people
- 20:14according to federal officials.
- 20:17The first 2 infected individuals in this outbreak had only severe eye infections,
- 20:22possibly due to exposure to contaminated milk.
- 20:26However, this third case marks the first time during this outbreak that respiratory symptoms
- 20:31have been observed.
- 20:33All three individuals had direct exposure to dairy Chow.
- 20:37And so far, there has been no evidence that the virus has spread to other people.
- 20:43Doctor Neerav Shah, the principal deputy director of the Centers for Disease Control And
- 20:48Prevention, emphasized that the virus called H5N1, has not acquired the ability to spread
- 20:54among humans.
- 20:56This newest case does not change the centers for disease control and Provention's H5N1
- 21:02influenza risk assessment level for the general public.
- 21:05Doctor Shah stated during a news Chi-Ming.
- 21:08We should remain alert not be alarmed.
- 21:11Despite the reassurance from the Centers for Disease Control And Prevention, The presence of
- 21:16respiratory symptoms in the latest case does highlight the need for continued vigilance.
- 21:22The H5N1 virus is known for its potential to cause severe disease in humans, and any signs
- 21:28of increased transmissibility are taken very seriously by health authorities.
- 21:34The Centers for Disease Control And Prevention is working closely with local health
- 21:38departments and agricultural agencies to monitor the situation and prevent further
- 21:43spread.
- 21:44Measures include increased surveillance of farm workers and dairy cattle, as well as enhanced
- 21:50biosecurity protocols on farms.
- 21:53The Centers for Disease Control And Prevention is also urging farm workers to take preventive
- 21:58measures such as wearing protective gear and practicing good hygiene to minimize the risk of
- 22:04infection.
- 22:06Public health officials are also advising anyone who has had direct contact with dairy
- 22:10cattle to be vigilant for symptoms and to seek medical attention if they experience any signs
- 22:15of illness.
- 22:17While the current risk to the general public remains low, this situation underscores the
- 22:22importance of monitoring zoonotic diseases, those that can be transmitted from animals to
- 22:29humans.
- 22:31The H5N1 virus has historically been associated with poultry, but its presence in dairy cattle
- 22:37is a new and concerning development.
- 22:40In summary, the detection of bird flu in a third farmworker, especially one showing
- 22:45respiratory symptoms, is a reminder of the ever present threat of zoonotic diseases.
- 22:51As health officials continue to monitor the situation, it is crucial for those in direct
- 22:56contact with farm animals to adhere to recommended safety measures to protect
- 23:00themselves and others.
- 23:03That brings us to the end of today's episode.
- 23:05Thank you for joining me on morning medical with Doctor Chow.
- 23:09Stay informed.
- 23:10Stay healthy, and we will see you next time for more updates on the latest medical and health
- 23:14news from around the world.