622-Functional Connectivity Gradients Across the Human Brain

Paper Talk · Mar 11, 2026 · 20m

This research article investigates the functional organization of the human brain by identifying shared connectivity patterns across the isocortex, cerebellum, and hippocampus. Using advanced gradient mapping on large neuroimaging datasets, the authors discovered that these seemingly distinct structures operate under a common systems-level framework. They identified two primary functional gradients that correspond across all three regions, suggesting a highly coordinated architecture for processing information. The study proposes that this structural alignment supports predictive processing…