Pharma 48: Bone, Minerals, and Memory - Holding the Frame Together

Clinical Deep Dives · Feb 3, 2026 · 1m

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This episode explores mineral ion homeostasis and bone turnover as the pharmacology of long memory. Bone is not inert scaffolding; it is a living archive that records hormonal signals, nutritional sufficiency, inflammation, and age. We trace calcium and phosphate balance, vitamin D activation, parathyroid hormone signalling, and osteoclast–osteoblast co…