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Dr. Neil Iyengar & Dr. Komal Jhaveri - Early-Stage HER2+ Breast Cancer: DESTINY-Breast11, DESTINY-Breast05 & What Comes Next
Recorded with Drs. Neil Iyengar and Komal Jhaveri, this in-depth discussion breaks down the most practice-shifting data in early-stage HER2-positive breast cancer — from neoadjuvant to adjuvant decision-making.
The conversation explores DESTINY-Breast11 and its unprecedented pathologic complete response rates with sequential T-DXd followed by THP, including an 83% pCR in hormone receptor–negative disease. The panel also examines safety, ILD risk, anthracycline-free strategies, and how these results may reshape neoadjuvant standards.
The discussion then moves to DESTINY-Breast05, where T-DXd…
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