Why Your Gut Is Sabotaging Your Hormones (and Your Hormones Are Sabotaging Your Gut) with Kiran Krishnan

The Hormone Solution | Menopause, Perimenopause, & Women's Midlife Health · Jan 10, 2026 · 1h 42m

I'm sitting down with microbiome expert Kiran Krishnan to explore a question I see come up all the time: why do hormones sometimes stop responding the way they used to? But what if the real issue isn't your hormones at all, rather what's happening in your gut?

In this episode, we dig into the powerful gut-hormone connection. How can gut bacteria influence estrogen metabolism, inflammation, weight gain, and even mood? Why do so many women struggle more during perimenopause and menopause despite "doing all the right things"?

We also talk about why hormone therapy sometimes backfires, how gut…