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The Molecule That Should Have Been a Psychedelic - But Broke Researchers' Stomachs
The Molecule That Should Have Been a Psychedelic - But Broke Researchers' Stomachs
Half a milligram supposedly produced mescaline-like effects, but the same compound triggered dysphoria and relentless nausea instead; why did a molecule that activated classic psychedelic receptors become defined by stomach-upsetting side effects? What happened to quipazine between a 1966 synthesis and a thesis sealed until 2030?
In this episode, we trace quipazine’s fifty-year scientific arc from a 1966 arylpiperazine synthesis to animal and fragmentary human reports, and ask whether its mixed pharmacology…
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