Breast Cancer — 5-Minute Journal Club Issue 2 with Dr Lajos Pusztai: Current and Future Role of Tumor-Informed Circulating Tumor DNA Assays

Research To Practice | Oncology Videos · Mar 18, 2026 · 30m

Featuring an interview with Dr Lajos Pusztai, including the following topics:

Circulating tumor DNA monitoring for patients with ER-positive, HER2-negative high-risk breast cancer during adjuvant endocrine therapy (0:00)

Clinical performance of a whole-genome assay for predicting disease recurrence (5:52)

Using circulating tumor DNA status to personalize CDK4/6 inhibitor therapy (12:46)

Neoadjuvant and adjuvant therapy stratified by circulating tumor DNA status (21:11)

Utility of circulating tumor DNA status in the management of metastatic breast cancer (24:55)

CME information and select…