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Vanda Pharmaceuticals: The Tradipitant FDA Approval Catalyst

Vanda Pharmaceuticals (VNDA) jumps after FDA approves its motion-sickness drug Nereus (tradipitant)

What happened

On December 30–31, 2025, the FDA approved Vanda’s Nereus (tradipitant) to prevent vomiting induced by motion. It’s the first new FDA-approved treatment for motion-induced vomiting in over 40 years, and Vanda says it plans to launch in the coming months.

Why the market cares

1. A brand-new FDA label creates a near-term commercial story (launch, pricing, payer coverage, distribution).

2. It also validates tradipitant as a platform asset, with Vanda pursuing other nausea/vomiting…

The skinny

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