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Deep Dive 2: Sex Differences in Alzheimer's Disease: Reproductive Health
This episode explores how reproductive ageing and biological sex influence Alzheimer's disease risk. Rachel Buckley discusses menopause, hormonal changes, genetic factors such as the X chromosome, and emerging evidence showing differences in tau accumulation between women and men.
Timestamps:
00:00:55:03 – Menopause and Alzheimer's disease
00:04:51:11 – X chromosome in Alzheimer's disease
00:08:29:01 – Tau accumulation in women
00:10:43:09 – Hormone replacement therapy
00:14:22:24 – The sweet spot with hormone therapy
The skinny
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