Latest / Harder Than Life / Why Your Body Can Heal Without Surgery: A Neurosurgeon's Guide to Peptides | Dr. Jeff Gross

Transcript

Why Your Body Can Heal Without Surgery: A Neurosurgeon's Guide to Peptides | Dr. Jeff Gross · Harder Than Life

• 0:00
  So you trained for years to operate on spines.
• 0:02
  Yeah.
• 0:03
  What did you see that made you want to do less of it?
• 0:05
  I've always wanted to do less of it.
• 0:07
  The art of medicine is knowing when not to do it.
• 0:10
  So we use exosomes for their regenerative capacity.
• 0:14
  And my biggest application is spine and joints.
• 0:18
  And I can speak on one-off cases of cartilage regeneration and avoidance of surgery.
• 0:24
  10 years from now, what is a normal care that sounds wild today?
• 0:29
  We'll have tissue-specific exosomes like neurological stem cell exosomes and myofascial muscle stem cell exosomes, not just regular stem cell exosomes.
• 0:38
  Even the GLP medicine for weight loss has a downside, you know.
• 0:42
  Oh.
• 0:42
  With semaglutide, a few episodes of blindness and pancreatitis, so we're watching very carefully.
• 0:48
  We don't see any downside to BPC-157 so far.
• 0:51
  It's been tested up to 20 milligrams intravenous.
• 0:55
  Most overrated thing in longevity right now.
• 0:57
  NAD Plus orally.
• 0:59
  Most underrated?
• 1:00
  Up tides.
• 1:01
  What are you doing for your own body that has nothing to do with an injection?
• 1:04
  I have a long list of biohacking that I do every day.
• 1:07
  So I will do... My guest today spent more than 20 years as a neurosurgeon operating on spines for a living.
• 1:13
  Then he walked away from most of it because he decided the better question was not how to cut something out of a person.
• 1:18
  It was how to get the body to rebuild itself.
• 1:22
  Welcome to the show, Dr. Jeffrey Gross.
• 1:23
  But today, we're going after the word everybody is throwing around that almost nobody can actually define, peptides.
• 1:32
  Let's get into it.
• 1:33
  Welcome to the show, doctor.
• 1:34
  Thank you for having me.
• 1:35
  I'm excited to share with you and dispel some myths and talk peptides.
• 1:40
  The audience is gonna hear this right after we had the Joy and Blokes people on, and this is gonna be more of a scientific deep dive.
• 1:46
  Dr.
• 1:46
  Gross is an expert in this, and we figured why not have him on right after we talk about regulatory and how to get them properly.
• 1:54
  So my goal,
• 1:56
  is to educate the art of the life nation on how to use things safely and properly and get access to them it's no secret i use peptides i am under doctor supervision now i got a friend here that we're going to share with you guys and be very very careful everybody with all of these influencers pushing peptides
• 2:19
  Be careful.
• 2:20
  Let's get into it.
• 2:21
  So you trained for years to operate on spines.
• 2:24
  Yeah.
• 2:24
  What did you see that made you want to do less of it?
• 2:27
  Well, I've always wanted to do less of it.
• 2:29
  I mean, the art of medicine is knowing when not to do it.
• 2:33
  And if you look at the menu of things you can do for someone with back pain, neck pain, things like that, surgery is at the last, it's the last thing you would ever get to unless there was some kind of acute emergency.
• 2:46
  And that's,
• 2:48
  You know, my job was to push that further down the list.
• 2:51
  The problem is the menu is written and driven by the health insurance slash sick care system.
• 2:58
  It's a very scripted cookbook, economically patterned to reward those people, not the patient.
• 3:06
  And these days, not even the health care provider.
• 3:10
  So it became clear that we diagnose things early.
• 3:12
  We have MRIs.
• 3:13
  We can figure stuff out earlier and before they're really messed up.
• 3:17
  So people have discomfort limitations, but they're not bad enough for surgery all the time.
• 3:21
  And there's that limbo.
• 3:22
  Well, I don't want the pills.
• 3:24
  The physical therapy wasn't enough.
• 3:26
  The injections were temporary, but I'm not ready for surgery.
• 3:29
  What else you got, doc?
• 3:31
  And we would look to fill that gap.
• 3:33
  And sometimes they would recommend, hey, doc, how about acupuncture?
• 3:36
  How about...
• 3:37
  You know, red light therapy.
• 3:38
  How about herbs?
• 3:39
  How about stem cells?
• 3:41
  And you hear stem cells enough.
• 3:43
  And some of my undergraduate work was in that field, but it wasn't ready way back then.
• 3:49
  So I said, one year I stopped going to the spine surgery conferences every year where we get our annual education hours because nothing was moving forward.
• 3:58
  Why?
• 3:58
  It didn't suit those that were economically rewarded.
• 4:02
  The people that make the screws and the rods, the people that make the bone grafts, the people that make the drugs that go with that.
• 4:10
  So one year I said, screw this.
• 4:12
  And I went to a stem cell conference and I started re-educating, retraining.
• 4:17
  And I wanted to add that as a tool in between things.
• 4:21
  injections, maybe surgery.
• 4:22
  But guess what?
• 4:22
  Now it's everything I do.
• 4:24
  It's branched into anti-aging and biohacking, all kinds of fun stuff.
• 4:30
  So spine surgery is a very small component of what I do.
• 4:33
  I still do some consultations, advise people how not to have it.
• 4:37
  Everybody that I know has had the back surgery, the fusion, so to speak.
• 4:42
  None of them.
• 4:43
  I mean, none have came out better.
• 4:45
  So you're telling me that you're a surgeon who says, do not do surgery.
• 4:50
  Yeah.
• 4:51
  Well, if you can't get out of bed every day because you're that bad and your clinical picture, how you are, how you feel, how you're doing, and your diagnostic tests match up and surgery is an option, you may be bad enough to have it.
• 5:02
  There's a role for it.
• 5:03
  I'm not saying take it all away.
• 5:05
  I'm saying it's overused.
• 5:06
  It's used too early.
• 5:07
  Why?
• 5:08
  Because MRIs find things early.
• 5:10
  Oh, you've got a small disc protrusion.
• 5:13
  Oh, you need a fusion.
• 5:14
  No, you don't need a fusion.
• 5:16
  Very few of those people need a fusion.
• 5:17
  Fusion is a very big and barbaric thing that was sort of figured out in the 1940s and hasn't changed.
• 5:27
  You heard it here first.
• 5:28
  Dr.
• 5:29
  Gross says it.
• 5:30
  I've been saying this and I'm not a doctor, but I've been saying do not get that surgery.
• 5:37
  Again, I know nobody, so it's good to hear that I wasn't, and I'm not totally crazy, but I am 50 now.
• 5:43
  And things don't feel the same that they used to.
• 5:46
  I used to be able to laugh an ache and a pain off simply.
• 5:50
  Why does it take so much longer for me to heal than when I was 25?
• 5:56
  Great question.
• 5:57
  So our healing capacity comes largely from our immune system's ability to respond to an injury called acute inflammation, do the repair, and then turn off and go away.
• 6:09
  If it doesn't turn off and go away, it leaves a smoldering trail of inflammation called chronic inflammation, and that degenerates tissues like cartilage.
• 6:19
  And then it begets more of these pro-inflammatory molecules, biochemicals we call cytokines.
• 6:26
  You might remember that word from the whole COVID thing, right?
• 6:29
  Cytokine storm.
• 6:31
  These people had severe inflammation in the heart and lungs and high fatality rate.
• 6:37
  But we can have this in our joints.
• 6:39
  Joints are sort of an early signature of inflammation in the overall body.
• 6:46
  And most things that lead to disease and lead to aging, and those are on the same plane, relate to the amount of chronic inflammatory changes at the cellular level.
• 6:58
  Not inflammation like, let's say you strain your wrist and it's swollen and red.
• 7:02
  Those are outward signs of gross inflammation.
• 7:06
  We're talking about at the cellular level, and that's where we now have tools to suppress that without necessarily reaching for pharmaceuticals.
• 7:16
  Are you recommending BPC for that?
• 7:18
  BPC-157?
• 7:19
  Yeah.
• 7:20
  I mean, that is a common component.
• 7:23
  of we'll call it an anti-inflammatory peptide signaling to suppress, to turn off that acute inflammation and turn off chronic inflammation and enhance the natural biological healing.
• 7:37
  Because these peptide signals we make in our body, they're natural.
• 7:40
  They're not drugs.
• 7:41
  Just like a hormone might decline over time.
• 7:45
  These peptides are in a way small hormones signaling at the cellular level, and you may need a little extra like you had when you were younger and healed faster.
• 7:54
  They're natural.
• 7:55
  Is that why you see it more generally mainstream versus a steroid, so to speak?
• 8:02
  Is that in your expert opinion?
• 8:04
  Perhaps.
• 8:04
  I think that's a component of it.
• 8:06
  Let's look at it from a different angle.
• 8:07
  Big pharma cannot patent a naturally occurring biomolecule.
• 8:13
  They can't patent glucose or insulin necessarily.
• 8:17
  They can do some modified form of it.
• 8:20
  For example, GLPs are peptides, right?
• 8:23
  You've talked about on your show, you know, weight loss, fat loss, preserving muscle, all the important stuff that goes with that.
• 8:29
  And GLPs we make in our body, but they disappear quickly.
• 8:34
  So we now have a class of drugs that are GLPs because they've modified them from the natural state to a slightly modified state.
• 8:42
  So it lasts longer in the body and does has a benefit.
• 8:46
  And they're great.
• 8:47
  But that's why they can patent those.
• 8:49
  But they can cannot patent BPC body protection compound 157 because your body, my body, everyone's body makes it.
• 8:59
  Body protection compound.
• 9:01
  I did not know that.
• 9:02
  But I know this much.
• 9:04
  That stuff works, folks.
• 9:06
  And we're going to get in the weeds of this.
• 9:07
  Probably going to get this episode banned because we're going to get really in-depth to some things.
• 9:13
  We had to dance around the word peptide on the last show.
• 9:16
  I'm sure that this one will get flagged, but we'll do our best.
• 9:19
  But what is the biggest thing people get wrong about peptides right now?
• 9:23
  Well, I think the first thing is they don't understand the regulatory side.
• 9:27
  And then second, they don't understand that there is a safe way to approach them and get the clinical guidance you need to not hurt yourself and to get a therapeutic dose.
• 9:39
  So we've got a lot of underdosing and overdosing because you saw it on social media, right?
• 9:44
  We have to do it responsibly.
• 9:47
  This seems like a very good point where we go into these research-grade peptides.
• 9:51
  What does that mean?
• 9:53
  Well, all peptides, you know, not all peptides are patented and yet approved for marketing claims.
• 10:00
  I said that very clearly and specifically.
• 10:03
  So because of that, they are not available at a regular pharmacy.
• 10:09
  So you can get them from either a compounding pharmacy or a lab that sources peptides and they call themselves research grade.
• 10:21
  A lot of those might be pharmaceutical grade, but they're not from a licensed pharmacy or pharmaceutical company.
• 10:27
  So everyone should know that the vast majority of peptides are produced, cleansed chemically and placed into a white powder in a large pharmaceutical facility in China.
• 10:41
  And the big suppliers, the importers in the U.S. that bring them over have to do third-party testing when they get here.
• 10:51
  They can't rely on the Chinese testing.
• 10:53
  That third-party testing looks for impurities.
• 10:56
  They look for that if it's BPC-157, that 99% or more of what's in that bottle is BPC-157.
• 11:03
  There are no toxins or leftover cleansing agents called TFAs.
• 11:08
  And that it doesn't have any infective particles called endotoxin.
• 11:11
  If it meets all these criteria, that's exactly what the pharmacies would do anyway.
• 11:15
  And that's kind of a pharmaceutical grade.
• 11:17
  That's what the big pharma companies do here in the US anyway.
• 11:20
  Those suppliers then sell them to all these peptide companies.
• 11:24
  And many of those peptide companies are doing it right.
• 11:26
  And they share with you that certificate of analysis.
• 11:30
  And that's how you can get a high quality product and getting exactly what you are expecting to get.
• 11:38
  That's the way it's done.
• 11:38
  Now, if you go to Timu,
• 11:41
  straight from China.
• 11:42
  It doesn't go through third-party testing.
• 11:44
  You have to rely on their testing.
• 11:45
  We don't recommend that.
• 11:46
  I didn't know that majority of peptides come from China.
• 11:49
  What is the percentage?
• 11:51
  Well, as far as I know, they all come from China.
• 11:54
  I would just, leaving it open in case there's some lab in Ecuador or Mexico or something that makes them.
• 11:59
  As far as I know, everything comes from China because it's so inexpensive to make them there.
• 12:04
  If we're not getting along with China these days, why wouldn't they just throw a bunch of fentanyl in it and wipe us out of the face of the earth?
• 12:12
  That's why we do the third party test when they get here.
• 12:15
  Exactly right.
• 12:17
  Again, I want to beat this peptide to a dead horse because everybody has a different version of it.
• 12:21
  Explain it to me like I've never heard the word peptide before in my life.
• 12:26
  Peptide is a fragment of.
• 12:29
  of a protein.
• 12:31
  Protein is one of the most basic and important biomolecules in our body.
• 12:36
  It's also a macro that we eat, right?
• 12:38
  We want to gain and build muscle and maintain that.
• 12:41
  We need our macros.
• 12:42
  We need to eat protein.
• 12:42
  We break down that protein in our gut with enzymes, which are also proteins, and those proteins are broken down into amino acids.
• 12:51
  And our body makes some amino acids, but we also have some we can't make.
• 12:55
  They're called the essential amino acids.
• 12:57
  And those amino acids are put together in certain fragment form in an order.
• 13:04
  And that particular peptide might bind a receptor.
• 13:08
  It might go into a cell.
• 13:09
  It might have a signaling to influence what's going on in those cells.
• 13:14
  For example, you want to stimulate the ability to gain more muscle.
• 13:18
  You want a peptide that helps your...
• 13:20
  pituitary gland release more growth hormone at night.
• 13:24
  So that is one of the things we use peptides for.
• 13:27
  And these are well known.
• 13:29
  They go back many decades of research as hormonal fragments or peptides.
• 13:35
  And now therapeutically, these come from Russia, right?
• 13:38
  The whole science of therapeutic peptides comes out of Dr. Cavinson's work in Russia, which,
• 13:44
  They were trying to enhance Russian soldiers and cosmonauts' ability in the 1980s.
• 13:51
  And, you know, when the Berlin Wall fell and Russia sort of started opening up, it took a while for us to get a hold of that research.
• 13:59
  And it's only now becoming super popular here in the States.
• 14:04
  Wasn't it back in the day, World War I or II, that they were giving the soldiers meth and now they gave them peptides?
• 14:10
  Now peptides.
• 14:12
  Yeah.
• 14:13
  Hey, we're getting better.
• 14:14
  Yeah, we're getting a little bit better.
• 14:16
  Yeah.
• 14:17
  No, the peptides, they got them from animal ground organs like thymus.
• 14:22
  Your thymus and beta peptide comes from the thymus gland, for example.
• 14:26
  Your TB500 is synthetic version of thymus and beta four.
• 14:31
  And TB500 is often paired with BPC157 as part of what we call the Wolverine healing stack or blend.
• 14:40
  Wolverine healings, ah, you know your stuff.
• 14:42
  I love it.
• 14:44
  Didn't I read somewhere where insulin is technically a peptide?
• 14:48
  Yes.
• 14:49
  Insulin is a protein.
• 14:51
  It's kind of big for a peptide, but it's sort of the original self-injection.
• 14:56
  So it dispels the myth that, you know, oh, I shouldn't be doing this at home.
• 15:00
  Are you kidding?
• 15:01
  You know, millions of people have injected themselves with insulin at home for many decades.
• 15:05
  The face cream, how are they in the same category?
• 15:09
  How are these...
• 15:10
  technically the same.
• 15:12
  Because they're all from the same molecular group of proteins and peptides and made up by amino acids.
• 15:18
  And some have signaling properties and some don't.
• 15:21
  For example, creatine, right?
• 15:23
  We all now know creatine is very useful, not only for muscles, but for brain health and heart health and so many things.
• 15:30
  And it's a great protein to have as part of your protein
• 15:33
  intake daily, it has signaling capabilities.
• 15:36
  It actually is telling cells what to do in a healthy way.
• 15:40
  So we are now tapping into that knowledge better and better.
• 15:43
  We have expanded information and knowledge that we didn't have a couple of decades ago, and now we're putting it to use.
• 15:51
  What is the difference between a drug that forces your body to do something and a peptide that asks it to do something?
• 15:58
  Because I'm hearing a lot of force versus pull.
• 16:01
  Yeah, I call it and others call it cell signaling.
• 16:04
  You know, when we look to natural ways to enhance healing or get a more youthful, restorative biology going like you had when you were younger, you could shake off the aches and pains.
• 16:16
  We're influencing our cells.
• 16:18
  Now, we can do that through lifestyle called epigenetics, where we're sleeping better and eating better and exercising smarter.
• 16:26
  Yeah.
• 16:26
  to enhance our stem cell activity, enhance our cells, signal to them that way.
• 16:31
  You could do fasting.
• 16:32
  You could do hot sauna.
• 16:33
  You could do cold plunge.
• 16:34
  They all have a signaling to our cells.
• 16:37
  Well, you can do it also through natural peptides.
• 16:41
  You could also do it through regenerative biologics, stem cells, exosomes, and we can save that for another day.
• 16:47
  But peptides are a very simple way to signal to our cells to get back to a more youthful biology, even if it's temporary enough to do the job we're asking it to do.
• 16:58
  So that is why it's a natural enhancement or pull and not a pharmaceutical overwhelming push.
• 17:07
  Heart and Life Nation, stay with me.
• 17:08
  I'm going to ask him a fun question after this next one about what his cocktail of choice.
• 17:13
  You talked about that Warriors cocktail, but every doctor has a stack that they recommend.
• 17:18
  But I have to ask one real quick thing before that.
• 17:22
  And actually two.
• 17:24
  Does an anabolic steroid, is that actually forcing the body to do something?
• 17:29
  And then the peptide is actually asking it to do something.
• 17:32
  Anabolic steroid is a modified molecule that has super anabolic effect on
• 17:39
  So it's a bit of a push, although it's a modified natural molecule.
• 17:43
  So you might say, so was GLP, right?
• 17:45
  So are the GLP medicines.
• 17:47
  So it's naturally modified, but it's such a big push that it can enhance you and cause problems.
• 17:53
  So you have to be very cautious with those.
• 17:56
  So what we're using and what have been tested on a lot of these peptides is they're from organ meats.
• 18:01
  If you're from, let's say, the Basque country in France, those folks like to eat all kinds of different organs from animals.
• 18:09
  They've been getting these for many, many, many generations.
• 18:13
  Right.
• 18:13
  So these organ meats, you can get them.
• 18:15
  And of course, we're not eating animals in the same way.
• 18:18
  Right.
• 18:19
  We're not using the whole animal like we did 400 years ago.
• 18:24
  So this signaling, especially in a world full of seed oils and processed foods and high fructose corn syrup,
• 18:33
  You know, our cells are horrible.
• 18:35
  We're seeing young people with low testosterone or cellular effects from all kinds of things.
• 18:40
  So this enhancement is sort of a return to nature to help put us back into a more youthful, restorative state, which is what we need.
• 18:50
  You just grossed me out in probably half the audience.
• 18:53
  It's an animal organs.
• 18:54
  Just so I know, what is a popular benefit of an animal?
• 18:58
  Give us one, just one to gross everybody out.
• 19:00
  An animal organ that you could eat and you get this.
• 19:04
  Well, I mean, there are a lot of people.
• 19:05
  I can't stomach these things, right?
• 19:06
  That's why I love that there are peptides.
• 19:08
  But there are people who will eat raw liver because it does have signaling effects for cells or things like that.
• 19:16
  There are benefits to those proteins because of the signaling.
• 19:19
  Yeah.
• 19:20
  So we now are tapping into the signaling without having to eat pancreas and tripe and things like that.
• 19:26
  And now for those of you out there that like tripe, God bless you.
• 19:29
  Go for it.
• 19:30
  It's just not for me.
• 19:31
  No, me neither.
• 19:33
  I get compared to liver king all the time, which now is shown that he was fake.
• 19:37
  Well, I shouldn't say fake.
• 19:38
  He was taking anabolic steroids.
• 19:39
  So the funny thing is, is be careful, guys.
• 19:41
  That's the number one thing.
• 19:42
  Be careful what you watch on social media.
• 19:44
  Yeah.
• 19:45
  I get a lot of people hating on me saying that I've taken steroids.
• 19:48
  And I've looked like this for 30 years.
• 19:50
  Exact same.
• 19:51
  30 years.
• 19:52
  I've lifted heavy.
• 19:53
  I ate right.
• 19:54
  You creatine and then just recently have figured out peptides.
• 19:59
  Why is this hitting so hard right now?
• 20:03
  Why are peptides so popular right now and not 10 years ago?
• 20:07
  Well, I think we know more about them now.
• 20:09
  I think the GLPs did the heavy lifting and made it more palatable to be able to inject yourself at home.
• 20:16
  And they're so effective, like, oh, these things might really work.
• 20:19
  I think we also have someone, a secretary of health who's open-minded and probably doing a lot of these things.
• 20:25
  I think we also have a little bit extra distrust of big pharma in the post-COVID era.
• 20:31
  So I think all these things have kind of converged.
• 20:34
  I think you nailed it.
• 20:35
  It's when you hit the most...
• 20:38
  prolific one which is obesity and it went overnight everybody takes notice so every doctor i've ever been to has a cocktail of choice and i call it a cocktail i'm an animal i'm a barbarian i don't know why um so you're you're highly intelligent and professional so if i'm a normal
• 21:03
  man walking in and I say, Dr.
• 21:06
  Gross, run my blood.
• 21:08
  What are you prescribing mostly to people?
• 21:11
  everyone's of course an individual and depends on their goals.
• 21:14
  You may be fully optimized.
• 21:16
  You may come in and say, I've got the right amount of muscle mass.
• 21:18
  Here's my body composition.
• 21:20
  I'm dialed in.
• 21:21
  I like my workouts.
• 21:21
  I'm feeling good, but I got some aches and pains.
• 21:24
  We probably look at my favorite healing slash anti-inflammatory stack called CLOW, K-L-O-W, which contains four peptides, all of which have separate but synergistic anti-inflammatory,
• 21:41
  angiomodulatory, which is a fancy term for stimulating the development of new blood vessels in the right environment, reduction of inflammation of the nervous system, which is good.
• 21:52
  And then it's got the copper peptides in it as well.
• 21:55
  The copper peptide called GHKCU, which people say is very good for skin and hair, which it is, but also has incredible influence and signaling of cells internally for suppression of inflammation and longevity.
• 22:08
  Yeah.
• 22:09
  And if we could suppress your ability to accumulate this chronic inflammatory cellular change, we are effectively slowing cellular aging.
• 22:18
  And if you slow the aging of your cells, well, are you not biologically slowing the aging of their owner?
• 22:25
  Yeah, makes sense.
• 22:28
  I said prescribe loosely.
• 22:29
  Are you able to prescribe these all over the country or are you just in Vegas?
• 22:33
  It's an interesting concept.
• 22:34
  We'll call it peptide coaching.
• 22:36
  Yeah.
• 22:36
  where I will look over people's shoulders.
• 22:39
  They will acquire, we will tell them websites where we feel safe and we've vetted.
• 22:44
  I use them personally.
• 22:45
  If they bring us a new website that they buy it, we might say, okay, show us a certificate of analysis.
• 22:50
  Let me look at it.
• 22:51
  Make sure it's legitimate.
• 22:52
  It's third-party testing, all that.
• 22:54
  And then we would guide them on dosing.
• 22:56
  Most people need help with that.
• 22:58
  Social media dosing is not accurate at all.
• 23:01
  Okay, let's do the world of service because I actually got asked this three times this weekend.
• 23:07
  And I know this is against the rules, but let's just give a little range.
• 23:12
  BPC, I tell everybody, I take an oral pill daily because I lift really heavy and I'm 50.
• 23:18
  And then if something gets out of whack, then I take and I go on YouTube and I call my friends like you and I say, what's the proper dosage I'm now getting?
• 23:27
  compounded pharmacy, good stuff.
• 23:29
  So I have to make sure I dose.
• 23:30
  What is the proper way to dose BPC-157?
• 23:34
  Because guys, I'm telling you this stuff works.
• 23:36
  And the reason why it was banned, because it works.
• 23:40
  So what is the proper dose?
• 23:43
  Well, it was banned.
• 23:43
  They just released the one.
• 23:46
  Let's clear that up.
• 23:47
  It's not banned.
• 23:48
  It was not on a list that the FDA said that they would leave
• 23:58
  ability for a person to acquire and use it.
• 24:02
  Oh.
• 24:02
  Yeah.
• 24:03
  And again, that's all over social media incorrectly.
• 24:07
  And most attorneys don't even understand.
• 24:09
  So the FDA regulates marketing claims and they should.
• 24:13
  They're there for consumer protection.
• 24:16
  And they haven't approved for marketing claims any peptide except for GLP-1s and SS31 and I think one or two others like Tessa Morelin.
• 24:25
  That doesn't mean the other ones are unapproved or disapproved.
• 24:28
  That means they have not yet evaluated them.
• 24:33
  So buyer beware, but right to try.
• 24:37
  And as long as you're getting it from a reputable source with some coaching and guidance, there's no law you're breaking.
• 24:44
  Is it a prescription?
• 24:45
  No, because it's not a drug per se.
• 24:48
  Is it regulated by the FDA?
• 24:50
  Sure, for marketing claims.
• 24:51
  They do not regulate the practice of medicine.
• 24:54
  And this is something we have disinformation in on the stem cell side of my practice and all that.
• 24:59
  So again...
• 25:01
  And for compliance here, and to make sure Kelly's show is above board, what we're teaching today is for educational purposes.
• 25:08
  And we are not making any marketing claims that we are using peptides to cure or treat a disease or condition.
• 25:16
  By the way, PRP, not FDA approved for marketing claims.
• 25:20
  Vitamin D, IV fluids, so many things, not FDA approved for marketing claims.
• 25:25
  Same status, but you take vitamin D every day.
• 25:28
  Thank you for...
• 25:29
  Keeping me honest, I'm kind of a rebel and I ask for forgiveness, not for permission.
• 25:34
  This one, I got to dance to a fine line.
• 25:35
  I'm going to change that BPC question to me.
• 25:39
  Okay.
• 25:40
  I have a shoulder that just started bothering me and I'm going to go into my...
• 25:45
  thing that I got sent to me by my compounding pharmacy with BPC.
• 25:49
  I don't remember what they told me to take.
• 25:51
  I'm 220 pounds, 8% body fat, 50 years old.
• 25:56
  It's legit.
• 25:57
  Let's say it came from a legit place.
• 25:59
  What would you recommend?
• 26:01
  It's not debilitating.
• 26:02
  It's just a little twing.
• 26:03
  Yep.
• 26:04
  What would the dosage and length be for me?
• 26:07
  This is for me, people, nobody else.
• 26:09
  So, and we're talking about injectable, subcutaneous injectable.
• 26:13
  Yes.
• 26:13
  Okay.
• 26:14
  Yes.
• 26:14
  And remember, guys, people get all worried up about that.
• 26:17
  It's just like an insulin needle.
• 26:19
  Right.
• 26:19
  It's a very tiny amount of insulin syringe.
• 26:22
  By the way, folks, I had one on my desk here.
• 26:24
  An insulin syringe, they make different sizes, is typically one milliliter of fluid.
• 26:31
  And a unit is one one hundredth of that.
• 26:34
  And we measure this in units, right?
• 26:36
  10 units, 20 units, that kind of thing.
• 26:38
  So you're taking a fraction of a CC or a fraction of a milliliter.
• 26:42
  Okay.
• 26:43
  Now, the important thing is, the first thing we have to know is how many milligrams of BPC-157 are in that bottle and how many milliliters of fluid you use to reconstitute it.
• 26:56
  Because people come to me and say, hey, doc, I'm taking 20 units, but I don't know how it was reconstructed, reconstituted.
• 27:02
  So do you happen to know your milligrams, sir?
• 27:04
  I think it's 100 milligrams.
• 27:06
  Okay, so let's assume you have 100 milligrams in a vial.
• 27:09
  How many mLs of fluid did you put in there to reconstitute it?
• 27:12
  That's what I was kind of wondering what the reconstitution and what the recommended dose is.
• 27:16
  What would Dr.
• 27:17
  Gross say to Kelly Siegel if I got it from you?
• 27:20
  Legit is the day is long.
• 27:21
  What would the normal cocktail be?
• 27:23
  Typically, a plain BPC-157 comes in often a 10 or 20 milligram vial, probably even a five.
• 27:32
  So 100 would, you could get that from a compounding pharma.
• 27:34
  Oh, no, no, you're right.
• 27:34
  You're right.
• 27:35
  Sorry.
• 27:35
  No, no, no, no.
• 27:37
  If you can get 100, I have no issues with that because most people underdose BPC-157.
• 27:44
  Okay.
• 27:44
  That's what I was getting at.
• 27:45
  Yeah.
• 27:46
  So I would say we always start low anyway and tight trade up.
• 27:51
  We do that with the GLPs.
• 27:52
  Why do we do it with BPC?
• 27:53
  Because even a 220 pound, 8% body fat made of muscle meat gentleman fat,
• 28:01
  A little dose might go a long way.
• 28:03
  We don't know.
• 28:04
  Everyone's different.
• 28:05
  So I would start out with a dose that would be more like 500 micrograms.
• 28:11
  So depending on how you diluted it, I'd calculate the units.
• 28:14
  I can do the math.
• 28:15
  We had to take all kinds of math to get into med school.
• 28:17
  Now we get to use it.
• 28:19
  So we could teach you that, right?
• 28:20
  I want you involved in that.
• 28:22
  And then we might do that daily.
• 28:24
  for a week.
• 28:25
  And if it's not moving the needle, we may double it.
• 28:27
  We may go up.
• 28:28
  You could probably take two to four milligrams a day.
• 28:35
  of BPC-157.
• 28:36
  So if you're buying it in a 10 milligram vial, it's going to go real quick.
• 28:39
  If you've got a 100, great.
• 28:42
  I like that.
• 28:43
  It's hard to get.
• 28:43
  It's 10.
• 28:44
  You're right.
• 28:44
  Yeah.
• 28:45
  It's hard to get.
• 28:45
  You can have it custom made, but it's hard to get.
• 28:47
  Thank you for that.
• 28:48
  I danced the fine line on that and I stand corrected.
• 28:50
  I make a lot of mistakes and that's why I have smart people on me.
• 28:54
  It's a great question and it's a common thing.
• 28:56
  And I'm glad we had that conversation.
• 28:59
  And I would love if the...
• 29:01
  suppliers would make bigger amounts so you don't have to reconstitute it every few days well they want you coming back for more it's still a drug come on they gotta make money yeah the reason why this came up my dear friend i was with him for the weekend in montana and his knee was bothering him he's all natural and i'm like you've got to try this bpc and then i reminded him that i had you coming out i'm like we will dig deep into it so you understand what it is and after he hears this he's going to be very happy
• 29:28
  You talked a little bit about that GHKCU.
• 29:32
  That happens to be another one I am on.
• 29:34
  I just cut my nails or else you would have said how long they are.
• 29:37
  And then, you know, 50 years old, I got a full head of hair.
• 29:40
  Why is this so popular right now?
• 29:43
  Because many of our processes in our cells, like building collagen, requires copper.
• 29:50
  And copper has to be delivered.
• 29:52
  And so this delivery is through a specific molecule, a tripeptide, meaning three amino acids,
• 29:59
  made up of 1G, 1H, and 1K.
• 30:03
  And those are codes for three different amino acids.
• 30:06
  And that binds copper.
• 30:08
  It just so happens molecularly, the shape and the electrostatic forces bind to copper and deliver it to where it's needed in the cell.
• 30:15
  So that's one of the factors that GHKCU does.
• 30:19
  So you need that for healing and anti-inflammation, which is why I don't like to do BPC-157 by itself.
• 30:26
  For most inflammatory issues or healing, we're using these multi-healing stacks because it's a single injection.
• 30:32
  You can get it in one bottle.
• 30:34
  These go together well, even though you hear on social media, they're the same pH.
• 30:37
  They don't bind up.
• 30:38
  They work well together.
• 30:40
  And if 1% of them forms an unuseful peptide, so what?
• 30:43
  1%.
• 30:44
  So we love these CLO stacks.
• 30:48
  GLOW is three of them.
• 30:49
  CLO is four of them.
• 30:50
  Like if you're going to do it, do it, right?
• 30:52
  It's not that much more expensive.
• 30:54
  So we like the CLO, K-L-O-W, has four peptides.
• 30:58
  And we use it for surgical healing.
• 31:00
  People have, a colleague of mine just had a hernia repair.
• 31:03
  We got them on CLO early.
• 31:05
  Heal that thing faster.
• 31:06
  I have people with significant disc problems in their lower back.
• 31:09
  And I'm looking at them going, oh, you might need surgery.
• 31:12
  We put them on CLO and they feel amazing.
• 31:14
  I said, well, I know you've got a disc issue.
• 31:16
  If you feel good though, we don't have to rush and do anything.
• 31:18
  Let's watch it.
• 31:19
  So it's sometimes amazes me, not that it's curing the underlying cause, but sometimes it's enough to suppress the inflammatory component to get someone comfortable and have a quality of life and can function.
• 31:31
  Dr.
• 31:32
  Gross, I was going to wait to the end, but if somebody wants to work with you, they just go to your website and schedule a telehealth
• 31:37
  Yes, give us a call or Instagram or whatever.
• 31:40
  We love to help people with this because we want you doing it right.
• 31:44
  Proper.
• 31:44
  We want you getting proper advice and what have you.
• 31:46
  And sometimes it's just coaching and then they go off and do it on their own.
• 31:50
  Sometimes we continue a relationship like you.
• 31:52
  Your shoulder's really buggered up and the peptides aren't enough.
• 31:55
  Well, we have other tools, non-surgical tools in the regenerative medicine family that we can look at to help you.
• 32:02
  Yeah, I'm glad that you exist because honestly, if people are listening, again, my only advice, don't listen to anybody on social media.
• 32:09
  Research it.
• 32:11
  Be very careful about what AI tells you because it gets a little bit wonky.
• 32:16
  So the people like Dr.
• 32:17
  Gross are going to be even better than my friends over at Joy and Blokes because you can just tell.
• 32:23
  And I'm going to tell you by this question right here.
• 32:25
  So how do you personally decide something has enough evidence behind it to offer it to a patient?
• 32:30
  That's a very good question.
• 32:32
  So I do the deep dive and the homework.
• 32:34
  In fact, I'm involved in some peptide education for other clinicians.
• 32:37
  So I really have to know this stuff.
• 32:39
  So I will research it.
• 32:41
  I will look at the science that's out there, including animal studies, including basic science studies, including...
• 32:49
  the Russian studies that a lot of people disregard, even though there was some very well done work, and then observational stuff.
• 32:57
  I will talk to my colleagues.
• 32:58
  Do you use this peptide?
• 32:59
  What is your experience?
• 33:01
  What's the upside?
• 33:02
  What's the downside?
• 33:03
  We want to advise us to risks and benefits and potential adverse complications.
• 33:07
  We have very few with peptides compared to pharmaceuticals and compared to other endeavors, but even the GOP medicine for weight loss has a downside.
• 33:15
  You
• 33:16
  Oh.
• 33:17
  You know, with semaglutide, a few episodes of blindness and pancreatitis.
• 33:21
  So we're watching very carefully.
• 33:22
  We don't see that as a signal with terzepatide or retitutide, but they haven't been around as long.
• 33:28
  So we're watching.
• 33:29
  We're very cautious.
• 33:30
  We don't see any downside to BPC-157 so far.
• 33:33
  It's been tested up to 20 milligrams intravenous.
• 33:37
  Intravenous.
• 33:38
  There's a published study.
• 33:39
  So we don't see that it's as a harmful side yet.
• 33:43
  It hasn't been identified.
• 33:45
  But we're cautious and we watch people.
• 33:46
  And that's why we like to look over your shoulder for these things.
• 33:49
  So I look at that.
• 33:50
  We are not going to see large, randomized, placebo-controlled studies.
• 33:56
  Why?
• 33:56
  That's going to take many millions of dollars and have to go through one of these companies that advertises to bring people to do tests for money.
• 34:05
  And Big Pharma pays for those.
• 34:07
  And since Big Pharma can't patent these, those studies are going to be very difficult to do.
• 34:13
  So the reason why I already trust you, besides I know you, is the fact that you're a surgeon by trade, by study, and you don't recommend surgery.
• 34:22
  So if that doesn't tell you to listen to Dr. Grouse, nothing else does.
• 34:26
  We've talked about GLOW, CLO, BPC, I heard you say Tessa Morelin.
• 34:32
  Yeah.
• 34:33
  What is one to avoid?
• 34:36
  What is one that we don't know enough about, or it is not,
• 34:41
  doing what it says it does and it's causing harmful effects.
• 34:43
  Well, I don't know that there is anyone to avoid in the right patient, but we have to be very careful with the growth hormone secreting peptides like tesamoralin or tesamoralin, depending on how you pronounce it.
• 34:57
  hexamoralin, semoralin, ipamoralin.
• 34:59
  And I use ipamoralin and CJC 1295 in my practice.
• 35:03
  All of these stimulate growth hormone release, which stimulate not you to grow per se, but to enhance tissue growth, anabolism over catabolism.
• 35:13
  It means growth over wasting.
• 35:16
  So muscle, bone density, both of those things associated with longevity, especially if you're on a GLP,
• 35:23
  And you're losing fat, you're losing some muscle.
• 35:25
  So we have to enhance that muscle early before you lose it.
• 35:28
  You've got to maintain your muscle and enhance it.
• 35:31
  So you have to do those cautiously.
• 35:32
  You can hurt yourself.
• 35:34
  You can develop problems if you don't take that properly.
• 35:38
  Problems.
• 35:40
  Wait, hold on.
• 35:40
  Let me ask you this much.
• 35:42
  I am on Tessamoralin right now, and I used to be on Samoralin.
• 35:45
  And I love the Samoralin better than I like the Tessamoralin.
• 35:47
  I feel like I get a bigger pump.
• 35:48
  What would I need to be careful for?
• 35:50
  So you're talking directly to me.
• 35:51
  What do I need to look out for?
• 35:53
  Well, you don't want to completely turn off your growth hormone.
• 35:56
  Okay?
• 35:57
  So if you take too much, you turn off your own pituitary, and that can really affect...
• 36:02
  downstream in the body.
• 36:03
  You just want to enhance that growth hormone release.
• 36:06
  You need to take it at night.
• 36:08
  So you get the normal physiologic pulse.
• 36:10
  You're supposed to take it on an empty stomach has the best effect right at bedtime.
• 36:15
  You should be taking it five days a week and not seven.
• 36:19
  And then you should be cycling on and off to give your body a break.
• 36:23
  That was my next question with the craze.
• 36:27
  of this peptides.
• 36:28
  I'm seeing people not cycle off.
• 36:30
  So what do you recommend is a good time to let your body cleanse, so to speak?
• 36:37
  For something in that family of growth hormone releasers.
• 36:40
  So if you did four to six weeks on, you do four to six weeks off.
• 36:43
  Again, guided for your goals.
• 36:46
  As long as you're maintaining the muscle gains in those times off, you're
• 36:50
  and eating the right protein and doing all the good work that you do to maintain your muscles, lifting heavy and all that.
• 36:56
  So those things are all there.
• 36:58
  And of course, I wanted to add back to the last cautions.
• 37:02
  With the growth hormone secretagogues, you have to watch the sugar metabolism, insulin sensitivity.
• 37:09
  Some of them are more notorious than others for throwing that off.
• 37:14
  It can throw off your glucose metabolism, your sugar, how you handle sugar.
• 37:18
  without any other change in your diet or anything.
• 37:21
  So you got to look at that, maybe do some lab tests and body composition analysis is key.
• 37:25
  Don't just get on the scale.
• 37:26
  You really got to get one of those scales that does the breakdown.
• 37:30
  Before you get worried about me, now that I know you, I'll probably come to you, but every six months I'm getting blood drawn.
• 37:36
  I'm getting everything tested.
• 37:37
  I do the bare bones.
• 37:39
  I do the lowest possible dose of everything I can do.
• 37:43
  Five days a week, three months on, three months off.
• 37:47
  I'm,
• 37:48
  Like mine is effort and energy.
• 37:49
  And I'm also sleeping right, eating right, stress right.
• 37:54
  So it's not just, oh, he takes peptides.
• 37:56
  No, no, no, no.
• 37:57
  I do the whole gamut that Dr.
• 37:59
  Gross would tell you to do as well.
• 38:01
  Wonderful.
• 38:02
  You got to do the work.
• 38:04
  You got to do the foundation set.
• 38:05
  You got to prepare the soil before you plant the seeds here.
• 38:08
  Cool.
• 38:08
  All right.
• 38:09
  We're going to bring this thing full circle because I know stem cells are a big part.
• 38:12
  We talked about those mitochondrials.
• 38:14
  And I want to talk more into that because I joke around that my followers know.
• 38:20
  And I'm not joking around about this anymore.
• 38:22
  I'm 50.
• 38:22
  I feel like I just got to know myself.
• 38:26
  mentally, physically, everything is slowing down.
• 38:30
  I'm at a level of peace in my life that I just wish for everybody in this world.
• 38:34
  I believe I'm going to live to 120, at least 100, but definitely I think 120 by the way that I take care of myself.
• 38:43
  So what are these mitochondrial peptides and why do they keep showing up in aging research?
• 38:48
  We are learning more and more about mitochondria, and it's one of the deep dives I've been working on recently.
• 38:54
  Mitochondria, we used to think were just the place where ATP was made in our cell.
• 38:59
  The energy, that's where energy comes from in our cell, and that's true.
• 39:03
  But it's more than that.
• 39:04
  It's sort of the CEO of the cell.
• 39:06
  The nucleus is important, but the mitochondria is a big conductor, and it is sort of the battery.
• 39:13
  And over time, the battery doesn't hold a charge like it used to.
• 39:16
  It leaks electrons.
• 39:18
  It has a short.
• 39:20
  One of the ways it gets shorted is by the COVID spike protein.
• 39:25
  So we have one peptide that helps seal the inner membrane of the mitochondria and make that battery a better battery.
• 39:33
  And that's called SS31.
• 39:35
  So we see a lot of people with esoteric energy loss and all kinds of just weird collection of symptoms along COVID.
• 39:43
  Maybe they have lines in the past, all kinds of things.
• 39:45
  We will try a mitochondrial repair cycle.
• 39:48
  It's a month of SS 31 daily.
• 39:50
  And because that one has a partial approval by the FDA for marketing claims for a particular disease, it's used off label.
• 39:57
  It's expensive because guess what?
• 39:59
  Big Pharma makes it.
• 40:01
  We do a month where we enhance the inner workings.
• 40:04
  We charge the battery.
• 40:05
  Yeah.
• 40:06
  and all the electron transport chain inside the mitochondria with something called MOTC.
• 40:10
  MOTC, you make naturally just like you make SS31.
• 40:14
  MOTC is released when you exercise.
• 40:16
  So Kelly, you probably have robust amounts of MOTC.
• 40:20
  MOTC is released by the mitochondria when you exercise, and it goes into the nucleus and tells it what genes to turn on to heal, grow, and develop.
• 40:30
  at a youthful clip.
• 40:31
  If you exercise a lot, you know that's protective against dementia.
• 40:34
  Why?
• 40:34
  Because you're signaling cells distant with that MOTC and other what they call myokines or exerkinds, small signaling biochemicals that leave the mitochondria from the muscles and go to other parts of the body.
• 40:50
  Well, we can do that with deliverable MOTC through an injection.
• 40:54
  Where does this
• 40:56
  NAD come into play?
• 40:58
  I'm going to keep going down the repair, aging, and resilience.
• 41:02
  Yes.
• 41:02
  Is NAD a part of this as well?
• 41:03
  Yeah.
• 41:04
  So still under the heading of mitochondrial health, you need all the pieces.
• 41:08
  NAD plus is the main biomolecule that's used to shuttle those electrons in the battery.
• 41:15
  You need it to charge and use the battery.
• 41:17
  So it's crucial.
• 41:20
  And there are many pathways in the body, in the cell, I should say that depend on it.
• 41:24
  And we have declining amounts with age, at least in the bloodstream.
• 41:28
  And there's some controversy whether or not it's actually declining in the cell.
• 41:32
  Probably is.
• 41:33
  And how you can take that.
• 41:34
  So if you take NAD plus orally, it's not doing anything.
• 41:38
  If you take an IV, it's not doing much because it doesn't really enter the cell.
• 41:41
  There's no NAD plus importer in the cell.
• 41:45
  So you see a lot of these supplements and things online.
• 41:48
  They're not doing anything.
• 41:49
  So how do you get NAD plus in your system?
• 41:51
  You can take something called NMN.
• 41:54
  which gets converted to NAD plus in the cell, or you could take NR, which is probably the best way, which is nucleotide riboside.
• 42:02
  And there's a supplement that you can take, you can buy called NR.
• 42:06
  And the best way to get NR is intravenous.
• 42:08
  You go into a high-end longevity doctor's clinic, maybe like mine, and we can give you NR intravenous.
• 42:16
  People do subcutaneous NAD plus shots.
• 42:18
  It's probably not enough.
• 42:20
  And again, it gets broken down before it gets into your cell.
• 42:23
  You can do an IV drip of 500 milligrams to a thousand milligrams, and you have to do it very slowly.
• 42:29
  It takes four to five hours of NAD plus.
• 42:31
  And still, you're not getting as much into the cell as you want.
• 42:34
  So I probably wouldn't spend too much time on NAD plus.
• 42:38
  I would look at a NAD plus precursor, something that becomes NAD plus in the cell.
• 42:43
  And that would be NMN or NR.
• 42:45
  Yeah.
• 42:46
  I wish I had this.
• 42:47
  I take a expensive NAD plus BPC-157 oral pill, and I have read it's a waste of time, and you just said it again, but there is a placebo effect that I feel.
• 43:01
  I'm not kidding.
• 43:02
  I stopped...
• 43:04
  And I felt a little, little ache.
• 43:06
  I felt a little older.
• 43:07
  And then I started taking it and I was like, I just keep doing it.
• 43:10
  What would you say to me if I just said that to you?
• 43:12
  Well, the BPC-157 is one of the few peptides you can take orally and it does have benefit in the gastrointestinal tract.
• 43:20
  So to the extent that it is doing some work on you and you're feeling better, I'm assuming that's going to be the main thing.
• 43:27
  way it does that.
• 43:28
  Is the placebo effect a real thing?
• 43:30
  Yeah, sure it is.
• 43:32
  And if that's part of what makes you feel better, I have no problem leveraging that.
• 43:36
  So keep taking it.
• 43:38
  I know what you're thinking.
• 43:39
  You're like, don't come to me, Kelly.
• 43:42
  You're the worst.
• 43:43
  I'm the worst patient ever.
• 43:44
  No, no.
• 43:45
  I mean, listen, if I were egotistical and maybe I was at one point, maybe a little bit left and because, you know, I'm a surgeon and and closed minded, I would say that's ridiculous.
• 43:55
  But it's not hurting you and it's helping you.
• 44:00
  Go for it.
• 44:01
  Yeah.
• 44:02
  You know, doc, I feel good and I, I, I'm doing good.
• 44:07
  We're spreading all this joy in with the podcast and the brand.
• 44:10
  And also my day job as an iCybersecurity guy.
• 44:14
  So we're protecting companies.
• 44:15
  And
• 44:16
  I'm just living a dream, man.
• 44:18
  And it's, it sounds like you are too.
• 44:19
  So let's go, let's help some more people.
• 44:21
  I want to still talk about this repair and aging.
• 44:24
  And you talked a little bit about this, the thymic peptide.
• 44:27
  So I want to talk a little bit about that.
• 44:29
  How does the thymic peptides fit into the immune side of getting older?
• 44:33
  So there are two main peptides from the thymus gland.
• 44:35
  And our thymus gland is part of what actually creates our immune system.
• 44:39
  And then it sort of shrivels up and goes away.
• 44:42
  It doesn't do much.
• 44:43
  But the first one is the TB500, which is part of that anti-inflammatory CLO-GLO healing stack Wolverine protocol.
• 44:52
  And then there is thymus and alpha one.
• 44:55
  Thymus and alpha one is incredibly stimulatory for the immune system in a good way.
• 45:00
  So it's used to help improve people with low immunity or impaired immunity.
• 45:05
  Maybe it's an intelligent play instead of a flu shot.
• 45:09
  As seasons change.
• 45:11
  Or in addition to a flu shot.
• 45:13
  Or, hey, I'm going to be doing a lot of traveling, be on airplanes full of sick people.
• 45:16
  You share in the air with them.
• 45:17
  Maybe I'll do a thymus and...
• 45:21
  alpha one cycle.
• 45:23
  Where can you get that from?
• 45:24
  In the same place you get your BPC.
• 45:27
  Yeah.
• 45:28
  Okay.
• 45:28
  Alpha one is very common.
• 45:30
  And you know, you might use it's part of an anti-aging longevity regimen.
• 45:33
  If your immune system is improved and enhanced, you have a better chance of longevity because your, your immune systems, what removes accidental damaged cells and cancer cells to the extent it can.
• 45:45
  All right.
• 45:46
  We're going to make a small.
• 45:49
  ever so slight turn to the right just a little bit because i could tell you eyes lit up when we talked about stem cells and exosomes so you said stem cells maybe yesterday's story and exosomes are where this is going
• 46:04
  make the case and make it make sense for me.
• 46:08
  So we now know that stem cells have an amazing ability to help enhance and heal.
• 46:14
  And they signal in a different way than peptides.
• 46:17
  And sometimes the two together, which I do a lot of, have synergistic benefit.
• 46:23
  Yeah.
• 46:23
  But we now know that stem cells, we give them to you and your body, they're gone and done in a day or two.
• 46:29
  But the benefits last much longer beyond that and can even become permanent, like a healing something.
• 46:35
  Well, wait a minute.
• 46:36
  The stem cells are gone.
• 46:37
  What's doing the signaling?
• 46:38
  It turns out stem cells deliver things.
• 46:42
  Stem cells make and deliver peptides and proteins called growth factors.
• 46:48
  You find those in PRP, for example, and they deliver vesicles, smaller vesicles.
• 46:54
  subcellular sized membrane encapsulated contents.
• 46:58
  Those contents might be lipids, micro RNAs, and other peptides and growth factors that are delivered at high efficiency into neighboring cells so they can get the message.
• 47:09
  The message might be, get back to work.
• 47:11
  Stop goofing around with that inflammation.
• 47:13
  Get back to healing.
• 47:14
  Get back to youthful mode, restorative mode.
• 47:17
  So it turns out that stem cells work through these signals and these signals, you can now skip the delivery, the Amazon truck and go right to the package.
• 47:26
  And the package is less expensive.
• 47:29
  It's more concentrated.
• 47:30
  It travels better through tissue.
• 47:32
  It crosses the blood brain barrier.
• 47:34
  It's the reason why a pregnant woman has glowing skin and shiny growing hair.
• 47:40
  She's getting a daily dose of stem cell exosomes
• 47:44
  into her bloodstream through the placental barrier.
• 47:47
  She's not getting stem cells.
• 47:49
  Those stem cells are half foreign to her, half the genetics from the father.
• 47:54
  And we don't want her to reject them or the baby.
• 47:56
  So the baby in the womb are protected, but the exosomes are a thousand times smaller.
• 48:00
  They can pass.
• 48:01
  And she gets this amazing, youthful injection daily and she deserves it.
• 48:07
  She's about to carry on the species.
• 48:09
  She needs a survival advantage.
• 48:11
  So we use exosomes for their regenerative capacity.
• 48:15
  And my biggest application is spine and joints.
• 48:19
  So we have examples, and I can speak on one-off cases, of cartilage regeneration and avoidance of surgery, which is back to my original theme.
• 48:29
  Nice.
• 48:29
  Nice.
• 48:30
  I love it.
• 48:30
  We're getting up against it, but I have five more questions.
• 48:33
  And I'm going to ask you to keep the answers short because these are, for the audience, these are showstoppers.
• 48:39
  I should have asked these earlier.
• 48:41
  I won't do any follow-up, but they're very important.
• 48:44
  And I labeled them safety sourcing and starting.
• 48:47
  So we talked about this, but I want to hammer it.
• 48:52
  A person can order a peptide online in about 90 seconds.
• 48:55
  What should worry them about that?
• 48:57
  It's a little too accessible.
• 48:59
  There's no oversight and people are doing it yourself.
• 49:02
  So please get coaching.
• 49:04
  Reach out to this gentleman.
• 49:05
  He knows his stuff backwards and forwards.
• 49:07
  And trust me, I was asking questions that I knew the answers to and there's something I didn't and I got school today.
• 49:13
  So this has been great.
• 49:14
  I know the audience has been well.
• 49:16
  What should somebody ask a clinic before they hand over a credit card?
• 49:19
  Let me see the certificate of analysis.
• 49:21
  If you're buying the peptides from that clinic, I don't really sell peptides.
• 49:24
  That's not my job.
• 49:25
  So, but if you do buy them somewhere, I want to see the certificate of analysis.
• 49:30
  I want to see everything about that peptide, where it was made, where it was tested, where
• 49:35
  a lot number, the expiration date, everything.
• 49:38
  I want to follow up on this one because I've tried a lot of clinics that don't sell.
• 49:42
  I've heard doctors, watched doctors prescribe a cocktail for everything.
• 49:47
  How can the average Joe know that you're just not going stamp, stamp, stamp?
• 49:52
  And I know you're not, but I'm using you as an example.
• 49:54
  Yeah, no, no, it's fine.
• 49:57
  So doc, have you taken this stack and what for?
• 49:59
  Cause most of the docs that are recommending these are taking them to, we've seen the light.
• 50:03
  Go into it yet.
• 50:04
  That's my last question.
• 50:05
  So don't go into yours.
• 50:07
  All right, good.
• 50:08
  Do you want to expand on that at all?
• 50:10
  No, I think that's the best way to approach it.
• 50:11
  Like, is this good enough for your family or you doc?
• 50:14
  Okay.
• 50:15
  This one is very important to me because not everybody can have access to this.
• 50:18
  If a person cannot afford any of this, what actually moves the needle for free?
• 50:23
  Exercise, exercise, exercise, proper sleep, clean, healthy, non-processed food.
• 50:30
  A couple supplements.
• 50:33
  Most people are deficient in vitamin D3, even if their lab number is normal.
• 50:38
  Talk to me about that later, maybe.
• 50:40
  Omega-3, omega-3, omega-3.
• 50:42
  probably a probiotic.
• 50:43
  You got to take care of your microbiome.
• 50:45
  Three times.
• 50:46
  Those are some basics.
• 50:47
  I got more, but you could, you could be healthy for free very easily.
• 50:50
  For me.
• 50:51
  And I've, I've can beat a dead horse.
• 50:53
  Sleep, sleep, sleep, and more fricking sleep.
• 50:56
  I used to say I'll sleep when I'm dead.
• 50:58
  And then if I wouldn't have started sleeping, I probably would be dead already because I got to get seven hours minimum.
• 51:03
  Wish I could get eight, but I just, it just never happened.
• 51:05
  So, all right.
• 51:06
  These last two are very, very personal to you and your office.
• 51:10
  Somebody listening wants a real doctor to look,
• 51:12
  at their real situation.
• 51:14
  What happens on a discovery call?
• 51:15
  Let's re-celebrate.
• 51:16
  Well, we start out where people want to start out.
• 51:19
  So, okay.
• 51:20
  Give me your medical background.
• 51:21
  Okay.
• 51:22
  I know all the surgeries you had, know the medical issues you've dealt with or may still have, what medicines you're on, all that, your allergies, what have you.
• 51:27
  What do you want?
• 51:28
  What do you want?
• 51:29
  What are your goals?
• 51:30
  Do you want to change your body composition?
• 51:32
  Do you want to have more energy?
• 51:33
  Do you want to live longer?
• 51:35
  Do you want to do all those things?
• 51:36
  Okay.
• 51:36
  Let's dig in.
• 51:37
  We start with the basics.
• 51:39
  diet, sleep, all those things.
• 51:41
  And we build on that.
• 51:42
  Maybe we do some lab tests.
• 51:43
  Maybe we do a bone density test.
• 51:45
  Maybe we do some fancy tests.
• 51:47
  It just depends.
• 51:47
  You got knee pain, maybe we do a specialized MRI to look at the exact problem.
• 51:51
  We will customize, we call it precision medicine.
• 51:54
  We customize it for that person.
• 51:56
  And we dig in and we build on that, right?
• 51:59
  We're building a pyramid and we got to build it so that people can meet their goals.
• 52:04
  Very, very good.
• 52:05
  And I'm impressed by you, and I would go to you in a heartbeat.
• 52:08
  Two-part final question.
• 52:11
  What are you doing for your own body that has nothing to do with an injection, and then what?
• 52:16
  are you taking what peptides are you taking that is possibly got it well i mean i have a long list of biohacking that i do every day and i'd say that the newest thing we've added in the last few months is a really high-end red light therapy at home so we'll do some methylene blue supplement because that helps absorb the light in the mitochondria so again i'm doing the deep dive
• 52:44
  10 to 15 minutes of red light therapy in the morning and 10 to 15 minutes red light therapy in the night before bedtime to simulate sunrise, sunset, reset my circadian rhythm and get some of those healing red and near infrared frequencies at high irradiance.
• 53:02
  This isn't just a mat.
• 53:03
  This is a panel.
• 53:04
  That draws some wattage at home.
• 53:08
  And I've had improved energy.
• 53:11
  Not that I had deficiencies because I do so many things, but I've improved energy.
• 53:16
  My skin has been better and I just kind of feel good.
• 53:20
  And it could be placebo effect like you sometimes, but it's easy to do, you know, and even the dog crawls up and curls up underneath it.
• 53:28
  So they know stuff.
• 53:30
  What's your go-to peptide?
• 53:32
  Oh, yeah.
• 53:33
  Well, Cloestack is easy.
• 53:34
  So I'll take Clo with me when I travel.
• 53:37
  You know, when we take the grandkids to Disneyland and we walk 20,000 steps a day and I've been on my feet since what they call rope drop when it opens at seven something or eight o'clock in the morning.
• 53:49
  Yeah.
• 53:49
  Yeah.
• 53:50
  I will up dose in those evenings.
• 53:52
  And by the end of a trip, even our kids, they want to, oh, can we sit down?
• 53:56
  I got to put my feet up.
• 53:57
  And my wife and I are like, no, we're ready to go.
• 53:59
  We're on Clo.
• 54:00
  So now all the kids are taking Clo.
• 54:05
  this might be a little too personal.
• 54:06
  How old are you?
• 54:07
  60.
• 54:07
  Get out of town.
• 54:09
  You look like a little kid.
• 54:11
  Wow.
• 54:12
  I didn't mean that.
• 54:13
  I, you know, that sounds, you know, my wife says I haven't matured 12 anyway, so we're probably right.
• 54:18
  And what you, it just went up four levels in my book.
• 54:24
  So, all right, we end every show with rapid fire.
• 54:26
  Just one sentence and one, one word answer.
• 54:29
  I'm going to start it with.
• 54:30
  Wow.
• 54:31
  Wow.
• 54:32
  All right.
• 54:36
  Sleep, food, or movement?
• 54:37
  You only get one.
• 54:39
  Which one?
• 54:40
  Movement.
• 54:40
  I think the body adapts to survivability if it has to move.
• 54:44
  So movement.
• 54:45
  Most overrated thing in longevity right now?
• 54:48
  NAD plus orally.
• 54:51
  Most underrated?
• 54:53
  Peptides.
• 54:54
  One supplement you can actually take every single day.
• 54:57
  Vitamin D. If it were your own knee, surgery or no surgery.
• 55:02
  I should say surgery or BPC.
• 55:04
  No surgery.
• 55:05
  There are many things to try before that.
• 55:08
  Awesome.
• 55:09
  Awesome.
• 55:09
  One health claim on the internet you wish would disappear.
• 55:13
  The disinformation about the phrase FDA approved means, not really a health claim, but it inhibits so many people from getting what they could have.
• 55:22
  By the way, that's the first I've heard of that.
• 55:24
  And I've done a lot of research on this.
• 55:26
  So thank you for that.
• 55:27
  That's good.
• 55:27
  10 years from now, what is a normal care that sounds wild today?
• 55:32
  We'll have tissue specific exosomes like neurological stem cell exosomes and myofascial muscle stem cell exosomes, not just regular stem cell exosomes.
• 55:42
  All right, final one.
• 55:44
  Finish this sentence.
• 55:46
  The body wants to survive, adapt, and heal.
• 55:51
  Any final thoughts?
• 55:53
  I think this was awesome.
• 55:54
  We could do another hour.
• 55:55
  We've nailed everything, man.
• 55:57
  Guys, this is important.
• 55:58
  Hopefully,
• 56:00
  The algorithm doesn't stop this because this was a doozy.
• 56:04
  Guys, thanks for listening.
• 56:05
  Till next week, be harder than life.
• 56:07
  Please rate and share this podcast.
• 56:08
  I'm active on all social platforms and love to hear from my Seagull supporters.
• 56:12
  Each and every episode is sponsored by my company, National Technology Management, the easiest and best IT company to do business with, delivering peace of mind with technology every day, even simplifying cybersecurity.
• 56:24
  Visit trustntm.com for more info.
• 56:27
  Until next week, be harder than life.