Latest / WhiteBoard Medicine - Emergency And Critical Care
#311 Tumor Lysis Syndrome Explained: Pathophysiology, Diagnosis, Prevention, and Treatment
Tumor lysis syndrome is an oncologic emergency caused by rapid tumor cell breakdown and release of intracellular contents into the bloodstream. In this episode, we review the pathophysiology, risk factors, laboratory abnormalities, diagnostic criteria, prevention, and treatment of tumor lysis syndrome. Topics covered include: • What tumor lysis syndrome is • Why tumor lysis syndrome occurs • High-risk cancers and clinical risk factors • Hyperkalemia • Hyperphosphatemia • Hypocalcemia • Hyperuricemia • Acute kidney injury • Cairo-Bishop diagnostic criteria • Laboratory monitoring and risk…
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