071-A high-resolution Mouse Brain Cell Atlas
This article details the creation of a comprehensive, high-resolution cell-type atlas for the entire adult mouse brain. The research involved systematically generating two types of large-scale, single-cell-resolution transcriptomic datasets using scRNA-seq and MERFISH technologies. The study organizes over 5,300 distinct cell types into a four-level hierarchical taxonomy (classes, subclasses, supertypes, and clusters), further categorized into seven "neighborhoods" based on molecular and anatomical relatedness. A significant finding highlights the strong correspondence between a cell type's…
The skinny
The skinny isn't ready yet — notes appear once the transcript is processed.