Latest / Pharmacy Podcast Network / Trust Matters, Cell and Gene, & World Pharmacists Day | TWIRx
Transcript
- 0:36Speaker 1: Hey there, Welcome to Twerks. My name is Todd.
- 0:38Speaker 2: You're a founder of the Pharmacy Podcast, and I'm the
- 0:42Speaker 2: happiest guy on the planet because it's tworks Day. It's
- 0:46Speaker 2: Friday Day, September twenty sixth. I need it to be Friday,
- 0:50Speaker 2: really really, really bad. Just had a normal week throughout
- 0:54Speaker 2: this week. I don't know how your week's been. I've
- 0:57Speaker 2: been in a very upbeat and happy mood. But it
- 1:02Speaker 2: was a recovery week. Just got back from three back
- 1:05Speaker 2: to back conferences the NSP focusing on our specialty pharmacies
- 1:09Speaker 2: and pharmacists. That's wonderful. Shout out to Sheila Quette and
- 1:13Speaker 2: her team. Just an amazing crew. We love that time.
- 1:17Speaker 2: Three part series is coming out. I think it starts
- 1:20Speaker 2: next week. Shout out to Brady let us know. I
- 1:23Speaker 2: can't remember exactly. Then we went to Framework LTC's innovation
- 1:28Speaker 2: conference concentrating on the technology of long term care pharmacy,
- 1:32Speaker 2: and that was my roots. That's how I entered pharmacy
- 1:35Speaker 2: way back in two thousand and four. I'm getting old.
- 1:40Speaker 2: And we were able to bring together their partners, their
- 1:44Speaker 2: clients and really set the stage for the future of
- 1:48Speaker 2: what pharmacy technology in the long term care space is
- 1:51Speaker 2: going to look like and guess what AI was everywhere
- 1:56Speaker 2: and there's lots of questions and confusion, and I think
- 2:01Speaker 2: the element of today, which our theme today is trust,
- 2:05Speaker 2: and we're going to be talking about how trust matters,
- 2:08Speaker 2: who to trust the Public's perception of healthcare today very weird,
- 2:15Speaker 2: especially just this last week selling gene therapy. Cannot wait
- 2:19Speaker 2: to talk to Joe today. And just a shout out
- 2:22Speaker 2: to my pharmacists, my favorite providers throughout the world. It
- 2:26Speaker 2: was World Pharmacist Day just passed. I think it was
- 2:30Speaker 2: yesterday on Thursday, the twenty fifth, and just proud to
- 2:34Speaker 2: be in the industry, proud to serve. If there's any
- 2:37Speaker 2: pharmacist listening right now that you'd ever like to join
- 2:40Speaker 2: me on this Week in Pharmacy and you really want
- 2:42Speaker 2: to dial into something that you're passionate about, please reach
- 2:46Speaker 2: out to me.
- 2:46Speaker 1: We would love to have you. Hey, we are going
- 2:50Speaker 1: to dive.
- 2:50Speaker 2: In and review some review some news today and I'm
- 2:54Speaker 2: excited that I get to have a co host with me.
- 2:57Speaker 2: Don't usually get a co host all the time, but
- 3:00Speaker 2: doctor Melissa Smith is not a stranger to podcasting. She's
- 3:05Speaker 2: leading our pharmacogenomics podcast initiatives with her new show, which
- 3:10Speaker 2: is doing very well. And I just want to say
- 3:12Speaker 2: Happy Friday and welcome to TWRKS.
- 3:15Speaker 3: Good morning, Todd. Thank you for having me with you today.
- 3:18Speaker 1: You're very welcome. We are, like I.
- 3:21Speaker 2: Said, in kind of a strange land. That is the
- 3:26Speaker 2: United States Healthcare System. It's stranger than ever. And I
- 3:30Speaker 2: want to get into some news with you. So it's
- 3:33Speaker 2: now time for twarks News. I need to have like
- 3:36Speaker 2: a little voice over that says something dramatic, like tworks
- 3:41Speaker 2: news or something like that.
- 3:45Speaker 1: Yes, that would be cute, all right.
- 3:48Speaker 2: So first up, I wanted to talk about the FDA,
- 3:52Speaker 2: and once again you and I before we are in
- 3:56Speaker 2: the green room, Melissa and I are talking and we
- 3:59Speaker 2: both agree that there should be a moat, big gargantuan
- 4:06Speaker 2: moat with walls and with barbed wire guarding it. There
- 4:10Speaker 2: should be an island called the United States Healthcare System.
- 4:13Speaker 2: And that moat protects us from politics, it protects us
- 4:18Speaker 2: from nuance, it protects us from non evidence based and
- 4:22Speaker 2: of course this is a fantasy land, Melissa, because we
- 4:24Speaker 2: live in the real world, and so one of the
- 4:29Speaker 2: questions that came up on a TikTok, and I rushed
- 4:32Speaker 2: to the US Food and Drug Administration's page was what
- 4:37Speaker 2: are novel drugs?
- 4:38Speaker 1: What does that mean?
- 4:39Speaker 2: And so the definition on the FDA's page is novel
- 4:43Speaker 2: drugs or drugs never before approved or marketed in the US.
- 4:46Speaker 2: C FDA for information about all seds, cders, approved drugs
- 4:54Speaker 2: and biologic products. First of all, Melissa, do you know
- 4:57Speaker 2: what a CDER is with the set standboard?
- 5:00Speaker 4: Oh boy, let's see here, because I.
- 5:04Speaker 2: Don't know what that stands for, but they expect us
- 5:07Speaker 2: to know. And this is a publicly accessible site. So
- 5:10Speaker 2: I'm like, why would they say cd R?
- 5:14Speaker 4: Yeah, Center for Drug Evaluation and Research.
- 5:17Speaker 2: Okay, excellent, all right. So the reason why I wanted
- 5:21Speaker 2: to bring this up to our listeners is and from
- 5:25Speaker 2: your perspective when you're because Melissa is a consultant and
- 5:28Speaker 2: she digs deep into people's issues. He personalizes the medicine
- 5:32Speaker 2: treatments she hears from the physician. She grabs the football,
- 5:35Speaker 2: the treatment ball, and then you run with it. But
- 5:37Speaker 2: then you're making jukes, you're making adjustments, you're jumping over
- 5:41Speaker 2: obstacles with the patient, and you're kind of like, I
- 5:43Speaker 2: can't I have to talk about football because football is
- 5:46Speaker 2: in my mind. So I'm going to do football analogies
- 5:48Speaker 2: for the entire time as Melissa's sprinting down the field
- 5:51Speaker 2: with the treatment.
- 5:53Speaker 3: Being in this situation, right, But talk to me.
- 5:57Speaker 2: About when you hear a a new drug and it's
- 6:02Speaker 2: in a picture interest for whatever reason, especially if it
- 6:04Speaker 2: have impacted one of your patients, where do you go
- 6:07Speaker 2: for your information to really dig into it.
- 6:11Speaker 4: Well, the FDA website is a great resource because that's
- 6:14Speaker 4: where it's going to be approving newly approved drugs, but
- 6:17Speaker 4: also giving us a list of these novel drugs that
- 6:19Speaker 4: could be used in clinical trials, et cetera.
- 6:22Speaker 3: After I go there, I go.
- 6:24Speaker 4: Into what's available to me as far as the pharmacokinetics
- 6:27Speaker 4: and the pharmacodynamics because I am a precision medicine pharmacist,
- 6:30Speaker 4: so I utilize genetics to my benefit to really look
- 6:33Speaker 4: at how a patient may respond to medication therapies. And
- 6:36Speaker 4: what's nice about the research of bringing a drug to
- 6:39Speaker 4: development is we're always going to have pharmacokinetic information, so
- 6:43Speaker 4: we have insight into the four fifty enzyme activity, other
- 6:46Speaker 4: types of pathways that are going to be responsible for
- 6:49Speaker 4: eliminating or activating our drugs. So for me, even if
- 6:53Speaker 4: it isn't aligning per se with the research at first,
- 6:58Speaker 4: I can still get some intuition around wants to be
- 7:01Speaker 4: expected when the genetics can come into play with the
- 7:04Speaker 4: major players that I look at every day. So those
- 7:08Speaker 4: are that's a that's a that's kind of a route
- 7:10Speaker 4: of attack I take in my mind when approaching new
- 7:12Speaker 4: drugs that may not necessarily have all the evidence based
- 7:15Speaker 4: information there yet.
- 7:18Speaker 2: So that makes sense, and I would I consume information
- 7:21Speaker 2: probably different than you and different than anybody because we
- 7:24Speaker 2: all lean. There's people that tell me I love video
- 7:28Speaker 2: you know, there's people that say, hey, I love reading,
- 7:30Speaker 2: and then of course me, I love podcasts. I can listen,
- 7:33Speaker 2: I can absorb, and then the ultimate is finding a
- 7:37Speaker 2: podcast that then I can go read what they're talking about.
- 7:41Speaker 2: And that kind of leads us to once again the
- 7:44Speaker 2: theme of trust where where we're getting our information. And
- 7:47Speaker 2: I really like how you said that you're going to
- 7:50Speaker 2: the FDA site, but you're also looking to other, you know,
- 7:55Speaker 2: other resources, so you can kind of like that that
- 7:58Speaker 2: is in and of itself evidence based medicine. It's Okay,
- 8:01Speaker 2: here's the journal article on hyper lipidemia. But here's another
- 8:06Speaker 2: article on hyperlipidemia, and here's another article on a And
- 8:10Speaker 2: now you've kind of perused and read all three. And now,
- 8:14Speaker 2: as the person that's responsible for the care at the
- 8:17Speaker 2: point of care, right in front of the patient right there,
- 8:20Speaker 2: now you get to make some decisions. And I think
- 8:22Speaker 2: that's the beauty of the craft and the practice and
- 8:26Speaker 2: the experience of being a pharmacist. And I can only imagine,
- 8:30Speaker 2: but because I'm not a pharmacist, But is that kind
- 8:33Speaker 2: of talk a little bit more about how you come
- 8:35Speaker 2: to some of your decisions.
- 8:37Speaker 4: Yes, you really can't rely upon one site or one
- 8:41Speaker 4: source of evidence to really make a clear determination. And
- 8:45Speaker 4: that's what I was taught in school as well, is
- 8:47Speaker 4: that you really have to research all avenues, all perspectives.
- 8:50Speaker 3: And all things that are.
- 8:54Speaker 4: Well vetted, if you will, in terms of what we
- 8:57Speaker 4: can go off of. So for me, it's important for
- 9:01Speaker 4: patient safety to really utilize all avenues at my disposal
- 9:06Speaker 4: when it comes to clearly defining what a medication outcome
- 9:11Speaker 4: looks like for a patient, for sure, but you also
- 9:14Speaker 4: have to collaborate and speak to other people as well,
- 9:17Speaker 4: you have to take in different perspectives. That's provider MD
- 9:20Speaker 4: perspectives as well, because yes they're diagnosing. They have an
- 9:25Speaker 4: oversight of more things than I usually have access to
- 9:28Speaker 4: when it comes to their family, and it's important for
- 9:31Speaker 4: that to happen as well.
- 9:32Speaker 1: So not only is it reading.
- 9:34Speaker 4: It's actually communicating and speaking in an interdisciplinary fashion with
- 9:38Speaker 4: other providers too.
- 9:41Speaker 1: I love it excellent, all right.
- 9:43Speaker 2: Next in news, I want to share with the listeners
- 9:49Speaker 2: an organization made up of originally two brothers nerdy as hell.
- 9:54Speaker 2: They're so nerdy and so fascinating and so intelligent. They're
- 9:58Speaker 2: thinking like ten steps of head of processes. They are
- 10:03Speaker 2: now funded by a bigger organization and the name of
- 10:06Speaker 2: the organization is Nested Knowledge. You can go to Nested
- 10:10Speaker 2: hyphen Knowledge dot com and Melissa.
- 10:14Speaker 1: They're going to.
- 10:15Speaker 2: Take buckets of data clinical of course, and they're going
- 10:20Speaker 2: to tie it into some other databases like maybe a
- 10:22Speaker 2: medi span or something.
- 10:24Speaker 1: They're going to cross reference articles.
- 10:26Speaker 2: They're going to cross reference other databases and EHR systems
- 10:32Speaker 2: and personalized soap notes and personalized treatments and.
- 10:35Speaker 3: That's health records too.
- 10:37Speaker 2: Yeah, all together, and they're going to give it to
- 10:42Speaker 2: the pharmacists, give it to the physician, give it to
- 10:44Speaker 2: the nurse practitioner, and I'm blown away.
- 10:46Speaker 1: So nested knowledge, just like this week is crazy.
- 10:50Speaker 4: That is going to blow up the industry in a
- 10:54Speaker 4: good way because there's always been a lack of communication
- 10:58Speaker 4: between different EHR system that different hospital systems use, long
- 11:02Speaker 4: term care systems use, and by able to for this
- 11:05Speaker 4: technology to allow visibility into different I'm hoping that that's
- 11:10Speaker 4: kind of the concept that sounds like it is that
- 11:12Speaker 4: will allow for a better management overall for any patient.
- 11:16Speaker 4: I'm assuming this is a technology integrated and for the
- 11:19Speaker 4: practitioner to gain access to all information patient wise.
- 11:22Speaker 3: Right, is that the kind of concept.
- 11:24Speaker 5: Here, right?
- 11:25Speaker 2: That's right, and it's it's all personalized. So, you know,
- 11:29Speaker 2: precision medicine really became a strong buzzword about ten years ago,
- 11:33Speaker 2: and then it solidified about five years ago.
- 11:35Speaker 1: Then it really popped back up again.
- 11:38Speaker 2: You can actually practice precision medicine today, and in your case,
- 11:42Speaker 2: you're doing it in my opinion, now that we have AI.
- 11:46Speaker 2: If you're doing it without AI, you're doing it the
- 11:48Speaker 2: hard way. Even though you're still doing it and you're
- 11:50Speaker 2: still you're still doing it the I would say, like
- 11:52Speaker 2: the old fashioned way or the ball and the ball
- 11:55Speaker 2: and pestel. You're grinding up the personalized medicine. But now
- 11:59Speaker 2: we have a to take all these other sources of
- 12:02Speaker 2: data and the most important one is the patient's very
- 12:07Speaker 2: specific notes. But now you're combining all the specific notes
- 12:12Speaker 2: with all this trusted sources of information.
- 12:17Speaker 4: That's incredible and we live in a very cool time
- 12:20Speaker 4: right now to be able to have this integrated. This
- 12:22Speaker 4: is something that when I was in pharmacy school and
- 12:25Speaker 4: then early in practice, thought this was far off in
- 12:27Speaker 4: the distance, like it was a problem that just seemed
- 12:30Speaker 4: impossible to solve, right. But with the integration of AI
- 12:34Speaker 4: into the mix, it allows for it to come to fruition, right.
- 12:40Speaker 4: So I'm excited about it. And it allows for me
- 12:44Speaker 4: to be able to not have to invest so much
- 12:46Speaker 4: time in the searching of information, and it can allow
- 12:51Speaker 4: me to expedite my process significantly, so that way, ultimately
- 12:55Speaker 4: we're getting things out to the patient in a more
- 12:58Speaker 4: effective way where they're feeling happier, healthier, more empowered.
- 13:02Speaker 2: I love this exactly, exactly, and I think it's going
- 13:08Speaker 2: to lead to pharmacists becoming very creative with what they
- 13:13Speaker 2: dig into. I think of Daniel Plummer and the world
- 13:16Speaker 2: of pregnancy, in the world of getting pregnant. I think
- 13:19Speaker 2: of Nadia Archimbaugh in the way that she coaches sexual
- 13:23Speaker 2: health and mental health and the fusion. And I think
- 13:26Speaker 2: of Genaquin and Pdah. Like, you guys are all champions
- 13:30Speaker 2: and you're you're already these in my eyes, you're like
- 13:32Speaker 2: these superheroes. But now you're going to have like this
- 13:34Speaker 2: extra toolkit to go even better and deeper and.
- 13:39Speaker 1: And just do so much more. So, Yeah, I'm excited.
- 13:43Speaker 4: I like that term toolkit and it's essential in our
- 13:48Speaker 4: arsenal of tips and tricks that we pull out for
- 13:51Speaker 4: us to be that much more proficientctly.
- 13:56Speaker 2: So if you go to once again nested dash Knowledge
- 14:00Speaker 2: dot com, you can get it for free.
- 14:03Speaker 1: Just try it out, poke around, tell it free.
- 14:07Speaker 3: That's even cooler.
- 14:08Speaker 2: Yeah, try it out for free and then you know,
- 14:11Speaker 2: let me know what you think. And then we'll get
- 14:13Speaker 2: back to the Calamus Brothers k A L. L. E.
- 14:17Speaker 1: Ms.
- 14:19Speaker 2: And they're just like I said, they're dynamic, and we're
- 14:21Speaker 2: going to be actually doing some work with them and
- 14:23Speaker 2: what they're going to help me with and By the way,
- 14:25Speaker 2: this stems off the word of trust. They're going to
- 14:28Speaker 2: be helping me with a standard, and the standard that
- 14:31Speaker 2: I've been working on since September of twenty twenty is
- 14:34Speaker 2: called evidence based podcasting. And what I've learned over podcasting
- 14:39Speaker 2: and pharmacy longer than anyone, and observing and listening to you,
- 14:43Speaker 2: and learning from pharmacists and learning from even patients and physicians,
- 14:49Speaker 2: and putting all this together, what I've learned is that
- 14:52Speaker 2: you have great respect for evidence based cataloging, data, repository journals,
- 15:01Speaker 2: and your podcasts that have exploded over the years. When
- 15:04Speaker 2: I started in two thousand and nine and they were zero.
- 15:06Speaker 2: Now there's about three hundred podcasts that are tied into pharmacy.
- 15:11Speaker 2: We have about forty two of those, and underneath that umbrella,
- 15:17Speaker 2: zero of those podcasts are evidence based. And that means
- 15:22Speaker 2: that your podcaster and your guest and the information that
- 15:26Speaker 2: you're talking about, and the journal that you're reviewing and
- 15:29Speaker 2: the article that you're digging into, that's well and fine,
- 15:32Speaker 2: it's still opinion because you didn't give it off to
- 15:35Speaker 2: two other people that have nothing to do with you.
- 15:38Speaker 2: They are completely unbiased. You know, they don't have any
- 15:42Speaker 2: reason to say anything this way or that way, but
- 15:45Speaker 2: they're going to critique, they're going to dig down, and
- 15:47Speaker 2: they're going to call you out if you've said something
- 15:50Speaker 2: on that podcast that is not truly evidence based. And
- 15:53Speaker 2: we're going to be coming up with this standard. The
- 15:55Speaker 2: standard is almost complete. We're about ninety eight percent completing
- 15:59Speaker 2: with the stand want to give a shout out to
- 16:02Speaker 2: pharmacists and continuing education providers that this is going to
- 16:07Speaker 2: revolutionize podcast supplemental learning. And I use the word supplement strongly, Melissa,
- 16:14Speaker 2: because I still don't believe that a podcast should ever
- 16:17Speaker 2: be the primary information. I think it should be secondary
- 16:21Speaker 2: and even evidence based podcasting. When you get to get
- 16:24Speaker 2: in your car and you're going to your treatment center
- 16:27Speaker 2: in a hospital, and you have a patient, it's a baby,
- 16:31Speaker 2: they have this blood disorder whatever, and now you can
- 16:34Speaker 2: listen to a podcast that on the way. It's a
- 16:36Speaker 2: fifteen twenty thirty minute show and it's the latest on
- 16:40Speaker 2: the XYZ disorder or whatever it was, and it's evidence based,
- 16:45Speaker 2: it's been peer reviewed.
- 16:46Speaker 1: So I think that that's important.
- 16:48Speaker 2: In an age where doctor Google has perverted medicine from
- 16:53Speaker 2: people diagnosing themselves and people are like, but I listened
- 16:56Speaker 2: to Joe Rogan, and people are like, I listened to
- 16:59Speaker 2: doctor Raw or this podcast or this podcast there, and
- 17:03Speaker 2: it's it's still not evidence based resources.
- 17:06Speaker 1: So what do you think of this concept?
- 17:09Speaker 3: I think it's important.
- 17:10Speaker 4: We're in an era where information online with I can't
- 17:14Speaker 4: tell you how many times I've had patients use that
- 17:17Speaker 4: same type of ideology of using Google to diagnose themselves
- 17:22Speaker 4: and then coming into a conversation with me with things
- 17:25Speaker 4: that are like just very low level of evidence or
- 17:28Speaker 4: just more I feel like whenever they go into let's
- 17:31Speaker 4: say Google or chat GPT, they're googling like very specific
- 17:34Speaker 4: things that they want answers to, and chat TOBT and
- 17:38Speaker 4: Google are not always going to give you the most
- 17:40Speaker 4: accurate interpretation of that information.
- 17:44Speaker 3: So that's important.
- 17:45Speaker 4: And that's where practitioners like physicians and pharmacists are so
- 17:49Speaker 4: instrumental and being able to be, you know, guiding lights
- 17:53Speaker 4: to that information because one we've gone through school for
- 17:57Speaker 4: so many years to be able to understand and interpret
- 18:00Speaker 4: this knowledge for you and truly err on the side
- 18:02Speaker 4: of caution for you to do no harm to you
- 18:04Speaker 4: as the patient. I mean, that's the idea here and
- 18:08Speaker 4: making a podcast available to practitioners and even out other
- 18:13Speaker 4: listeners who just want more evidence based, true information than
- 18:18Speaker 4: just listening to some influencer online about how they should
- 18:22Speaker 4: be correcting their cholesterol with this supplement over here that
- 18:25Speaker 4: probably doesn't even have what the active ingredients that they're
- 18:28Speaker 4: looking for in it, because nothing's being vetted that way either.
- 18:31Speaker 4: So we live in a very tricky time. And being
- 18:33Speaker 4: able to provide the public practitioners with a podcast that
- 18:39Speaker 4: truly vets the information and only showing the higher levels
- 18:42Speaker 4: of evidence that surround the different topics and conditions and
- 18:46Speaker 4: medications that we're trying to work with with our patients
- 18:49Speaker 4: is important and truly is a big responsibility. So it
- 18:55Speaker 4: takes a person like yourself Todd to be able to
- 18:58Speaker 4: bring all like minds together. They're in this and bringing
- 19:01Speaker 4: it to the forefront and making it available.
- 19:05Speaker 2: Yes, I and and the the fast track of all
- 19:09Speaker 2: of this is we we experimented with evidence bace podcasting
- 19:14Speaker 2: with Eli Lilly back in twenty eighteen when they when
- 19:17Speaker 2: they were doing a podcast on trulicity Doctor Doctor.
- 19:22Speaker 1: Yeah.
- 19:22Speaker 2: They they were intense and it took six months to
- 19:26Speaker 2: edit and to make that podcast truly evidence based and
- 19:31Speaker 2: pulling back the information and vetting it. And then they
- 19:33Speaker 2: had peer reviewers that were you know that we're encouraged
- 19:37Speaker 2: to review and give feedback, and we had to change
- 19:40Speaker 2: a couple of things. But it's there's no reason with
- 19:44Speaker 2: technology today and what we've done that we can't that
- 19:48Speaker 2: we can't.
- 19:48Speaker 3: Do this absolutely.
- 19:51Speaker 1: Yeah.
- 19:51Speaker 2: So also in the news, I want to give a
- 19:54Speaker 2: shout out. This comes from West Virginia News. That's wvnews
- 19:58Speaker 2: dot com. Shout out to that reporting they covered the
- 20:02Speaker 2: Orsini selected as a specially pharmacy partner for Krinetics. Pulse
- 20:07Speaker 2: of Paul SNIFFI, paulse NIFFI, I don't even know what
- 20:10Speaker 2: that drug is.
- 20:11Speaker 1: What is that drug melissautine.
- 20:13Speaker 3: I've never heard of the drug.
- 20:14Speaker 4: I'm going to be full transparency there. So let me
- 20:16Speaker 4: look at this and give you an.
- 20:18Speaker 2: Answer, obviously for a rare disease. But I want to
- 20:21Speaker 2: give a shout out to Nick Klla. He's a friend
- 20:24Speaker 2: of mine from Pittsburgh, Pennsylvania. He's been in specially pharmacy
- 20:27Speaker 2: for years. He joined me on the NASP podcast while
- 20:31Speaker 2: we were in Denver. I cannot wait to share his
- 20:34Speaker 2: interview with you, but a shout out to Orsini and
- 20:36Speaker 2: what you're doing in rare disease. I really enjoyed reading
- 20:39Speaker 2: this article and understanding that your partnerships with other companies
- 20:45Speaker 2: are opening doors, even though I had no idea what
- 20:48Speaker 2: the drug was.
- 20:49Speaker 4: Yeah, I'm looking at it right now, and it is
- 20:52Speaker 4: definitely a specialty drug for types of conditions like rare
- 20:55Speaker 4: endocrine disorders hYP prepare thyroidism, where blood disorders like sickle
- 20:59Speaker 4: cell dose and transfusion.
- 21:02Speaker 3: Let me see here, let's see here.
- 21:07Speaker 4: Specific for it though, it's the endocrine disorder, so hypo parathyroidism,
- 21:12Speaker 4: and then a pheno key tun urea PKU is also
- 21:16Speaker 4: a treatment, and then he So it's got a bunch
- 21:18Speaker 4: of indications hematology disorders like sickle cell like I was mentioning.
- 21:22Speaker 4: So yes, it's one of those specialty medications that I
- 21:26Speaker 4: don't necessarily see all time unless I'm in those particular fields.
- 21:32Speaker 2: Yeah, that's why it's especially they they're building workflow systems
- 21:36Speaker 2: for disease states now, and that disease state selection will
- 21:41Speaker 2: then open up libraries of information and treatment calls and
- 21:46Speaker 2: so especially it's crazy. It's it's one of my favorite
- 21:49Speaker 2: sectors of pharmacy, and how busy it's become.
- 21:52Speaker 4: Charmacists have to be in this line of work because
- 21:56Speaker 4: there's very specific pharmacists that are hired to only counsel
- 22:00Speaker 4: on this medication and work with the providers on the administration,
- 22:03Speaker 4: et cetera. I have a cousin that actually does that
- 22:06Speaker 4: in a specialty drug company. So yeah, it's involved. Because
- 22:12Speaker 4: it's not unique to the larger population, it's very specific.
- 22:17Speaker 1: Well, let's says your cousin. Is your cousin a pharmacist?
- 22:21Speaker 6: She is.
- 22:21Speaker 4: Yep, she's my cousin, Jason. He's a pharmacist with publics.
- 22:27Speaker 4: He is kind of higher up in publics in the
- 22:30Speaker 4: state of Florida. And then she has done this work
- 22:33Speaker 4: since she got out of school and it was a
- 22:34Speaker 4: long time ago when she graduated. I want to stay
- 22:36Speaker 4: back in two thousand and nine.
- 22:38Speaker 3: Is when they graduated from school. Wow, maybe it maybe
- 22:41Speaker 3: even a little earlier than that.
- 22:42Speaker 2: So it's cool it's in your family, yes, all right.
- 22:47Speaker 2: Next up, this kind of ties us back to the
- 22:50Speaker 2: word trust. And I've heard some disturbing feedback to some
- 22:57Speaker 2: of the boards of pharmacy throughout the country and how
- 23:00Speaker 2: once again it's just doing it the way. We've always
- 23:03Speaker 2: done it this way, So this is the way we're
- 23:05Speaker 2: going to do it. No, sir, you're not going to
- 23:07Speaker 2: do it that way. You're going to follow an evidence
- 23:09Speaker 2: space medicine. Shout out to Bernadette Melnick with this book EBP,
- 23:14Speaker 2: the EBP Competency Book Redefining Evidence Based Medicine. Her and
- 23:20Speaker 2: her partner Lynn Gallagher Ford doctor Ford and Ellen Overhault
- 23:26Speaker 2: wrote this book and this is what I based evidence
- 23:28Speaker 2: based podcasting on and being able to come up with
- 23:31Speaker 2: a format and a standard to assure that the information
- 23:34Speaker 2: that we're reviewing is in fact evidence based. And the
- 23:37Speaker 2: headline here from the Alabama Political Reporter is Alabama Board
- 23:42Speaker 2: of Pharmacy faces backlash over Open Meetings Act violation And
- 23:47Speaker 2: it kind of goes into the privacy issues that had
- 23:50Speaker 2: come up, as well as a settlement that's actually in place.
- 23:55Speaker 2: The trust that we think as the consumer that our
- 23:58Speaker 2: boards of pharmacy are assuring that information is phi is
- 24:04Speaker 2: kept in place. And it's just this is the third
- 24:08Speaker 2: time in a month that I've heard from news or
- 24:12Speaker 2: I've heard from a pharmacist that something's going on awry
- 24:16Speaker 2: at their board. Of pharmacy. And that's disturbing to me
- 24:19Speaker 2: because once again, I want to common denominator. I want
- 24:23Speaker 2: to hit the floor and I want to not sink.
- 24:26Speaker 2: I want to stay on something concrete, and I want
- 24:29Speaker 2: that to be based on health care trust. So the
- 24:33Speaker 2: boards of pharmacy are supposed to be kind of like
- 24:36Speaker 2: our police officers of the pharmacy industry and the standards
- 24:39Speaker 2: and making sure that one to two, one pharmacist to
- 24:43Speaker 2: two techs or you know, just the whole gamut of
- 24:46Speaker 2: what comes into play. But have you ever have you
- 24:49Speaker 2: ever had run ins either good or bad? And you
- 24:53Speaker 2: don't have to be specific, but anything tied back to
- 24:56Speaker 2: a board of pharmacy Melissa.
- 24:58Speaker 4: Not me personally, thank god, But I was reading a
- 25:02Speaker 4: little more deeply into this article and it's being pretty
- 25:04Speaker 4: vague about what the explicit like indicate what they're inferring
- 25:09Speaker 4: as far as an appropriate conduct with the Board of
- 25:13Speaker 4: Pharmacy members and one in particular through this. And that's
- 25:18Speaker 4: interesting that they're being that vague, right, because it almost
- 25:21Speaker 4: insinuates like a higher level corruption happening. And that's very
- 25:26Speaker 4: scary because when we have people that are coming into
- 25:29Speaker 4: what's supposed to be these unbiased entities that are overseeing
- 25:32Speaker 4: our practice of pharmacy in each of the states. We
- 25:35Speaker 4: can have a lot of overreach in those situations and
- 25:40Speaker 4: also more of a political sense of infusing things into
- 25:44Speaker 4: our practice as well, not necessarily, I mean, not always
- 25:48Speaker 4: in a bad way, but sometimes in a corrupt way
- 25:51Speaker 4: where it's more benefiting people outside of the practicing body
- 25:56Speaker 4: as a whole.
- 25:57Speaker 1: You know.
- 25:57Speaker 4: It just it is scary me personally, know, But I
- 26:00Speaker 4: mean when I think back into COVID times and then
- 26:03Speaker 4: that going into how we were administering the COVID vaccines
- 26:06Speaker 4: and the medications available, then I mean no, nothing, I
- 26:10Speaker 4: mean outside of that, I just it's more of me
- 26:12Speaker 4: thinking about how, in a blink of an eye that
- 26:15Speaker 4: we can have somebody just reach in and then really
- 26:18Speaker 4: differentiate what our practice looks like. So it is scary,
- 26:22Speaker 4: and you want people there that are you know, honest,
- 26:25Speaker 4: people that have the best intentions when going into that
- 26:29Speaker 4: particular role.
- 26:31Speaker 3: So yeah, unfortunately know, but thank you.
- 26:34Speaker 4: For making me aware of it. I'm going to be
- 26:36Speaker 4: following in a little more closely now.
- 26:38Speaker 2: Yeah, And I think a shout out to our pharmacists listening, Listen,
- 26:43Speaker 2: your boards of pharmacy. I think, down deep inside they
- 26:47Speaker 2: want to do what's best. I think they took those
- 26:49Speaker 2: positions because they felt a pride in securing and protecting.
- 26:55Speaker 2: But they're humans just like everyone else. They have stress,
- 26:58Speaker 2: they have, you know, things that are happening in their
- 27:00Speaker 2: own life which may impact the job of of and such.
- 27:04Speaker 2: I almost think that we have to almost come up
- 27:07Speaker 2: with rotations with boards of pharmacy to assure that someone
- 27:11Speaker 2: doesn't get complacent as someone who's ah there, I've I've
- 27:18Speaker 2: heard from pharmacists. There's some that are the the black
- 27:21Speaker 2: and white straight up and down really to the text
- 27:26Speaker 2: board of parmacy officer, and then the other ones maybe
- 27:30Speaker 2: they're bored or something like that. But yeah, So I
- 27:37Speaker 2: want to give a shout out to pharmacists listening today
- 27:40Speaker 2: once again it was World Pharmacists Day. Happy World Pharmacists Day.
- 27:44Speaker 2: To you, Melissa and into listening, You're very welcome. And
- 27:48Speaker 2: then a shout out to pharmacists interested in learning more
- 27:53Speaker 2: about precision medicine and pharmacogenomics. And if you don't know Melissa,
- 27:59Speaker 2: doctor Melissa Smith, please reach out to her on LinkedIn.
- 28:04Speaker 2: Very active, very involved, and you've helped a lot of
- 28:08Speaker 2: pharmacists understand what the potential is as making a pharmacogenomics
- 28:14Speaker 2: tool in their toolbox and their belt and really expanding
- 28:18Speaker 2: upon what it means to be a precision pharmacist.
- 28:22Speaker 3: Thank you so much.
- 28:22Speaker 4: Yes, I encourage anybody listening, especially pharmacists that are wanting
- 28:26Speaker 4: more insight into how to implement this.
- 28:29Speaker 3: I am available.
- 28:31Speaker 4: I've talked to pharmacists quite a bit about this because
- 28:34Speaker 4: there's so many reaching out with wanting to implement this,
- 28:37Speaker 4: and they know that it's going to be part of
- 28:39Speaker 4: clinical practice here in the upcoming years. It's here now,
- 28:43Speaker 4: but they're wanting to really champion it as well, and
- 28:47Speaker 4: speaking with me is helpful.
- 28:49Speaker 3: I give perspective.
- 28:50Speaker 1: It's right. Well, we've enjoyed this.
- 28:53Speaker 2: Thank you so much for being my co host today
- 28:55Speaker 2: on This Week in Pharmacy.
- 28:57Speaker 1: Shout out. What do you have any plans this weekend?
- 28:59Speaker 1: Are you? Oh, by the way, are you a football fan?
- 29:02Speaker 3: I'm a football fan.
- 29:03Speaker 1: I don't.
- 29:05Speaker 4: Well, I'm in Tampa area, so I'm with the Buccaneers.
- 29:08Speaker 1: Of course.
- 29:08Speaker 4: I went to University of South Florida. They just traded
- 29:11Speaker 4: divisions and they're they're doing well right now. They moved
- 29:15Speaker 4: up in the southeast, right, So those are typically the
- 29:18Speaker 4: ones I follow.
- 29:20Speaker 2: The Pittsburgh Steelers are in Ireland this weekend, and we'll
- 29:23Speaker 2: see what happens there. I don't even know who they're playing,
- 29:26Speaker 2: but I'm kind of like a lukewarm fan. I watch
- 29:30Speaker 2: and usually start watching a lot more seriously if there's playoffs.
- 29:33Speaker 1: But who knows.
- 29:36Speaker 3: I'm kind of I.
- 29:38Speaker 4: Follow, but I'm not not like some of my other
- 29:40Speaker 4: friends that are very die hard to their their different
- 29:43Speaker 4: schools they went to and what have you.
- 29:45Speaker 3: But what I want to do say is.
- 29:46Speaker 4: That I have my podcast episode airing on Monday here
- 29:51Speaker 4: on September twenty ninth. It was a great episode. I
- 29:55Speaker 4: was with my good friend doctor Vanessa Lesnski in that episode,
- 29:59Speaker 4: and we were talking about pharmacogenomics in the academics. She's
- 30:03Speaker 4: actually a faculty member at the Leecom School of Pharmacy
- 30:07Speaker 4: here in Florida and the Sarasota area, and we were
- 30:11Speaker 4: discussing a lot of things surrounding just implementing pharmacogenomics, what
- 30:14Speaker 4: it looks like for her with her students there, and
- 30:17Speaker 4: just kind of the undertone of enrollment with pharmacy. So
- 30:20Speaker 4: definitely take a listen.
- 30:23Speaker 2: If you would like to listen to all of those
- 30:26Speaker 2: podcasts under the banner of pharmacogenomics, just go to PGX
- 30:31Speaker 2: FORURX dot com. Once again, that's pg X four the
- 30:36Speaker 2: number four RX dot com and tune in on Monday
- 30:41Speaker 2: for the twenty ninth of September for the next episode
- 30:44Speaker 2: with doctor Melissa Smith.
- 30:46Speaker 1: I can't wait to listen.
- 30:47Speaker 3: Thank you, I appreciate it all right.
- 30:49Speaker 1: We will be right back on twerks. Don't go away.
- 30:56Speaker 7: Fueling lost with the complexities of pharmacy accounting.
- 30:59Speaker 8: In pharmacy today, there's so many different variables and issues
- 31:04Speaker 8: that impact the pharmacy, books, records, accounting, the profitabilities, sore
- 31:08Speaker 8: or so forth. There's different components of pharmacy that have
- 31:11Speaker 8: its own nuances from an accounting standpoint, and so it's
- 31:15Speaker 8: it's tricky, there's no doubt about it.
- 31:16Speaker 7: Ready to take your pharmacy to the next level, but
- 31:19Speaker 7: don't know where to start. Psychs and Companies here to help,
- 31:23Speaker 7: introducing the RX Assessment. With the RX Assessment, the pharmacy
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- 31:33Speaker 7: action steps you need to take to take your pharmacy
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- 31:40Speaker 8: who understands the industry and how the accounting and tax
- 31:44Speaker 8: should really be in a pharmacy, this is this is
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- 32:18Speaker 2: Hey, welcome back to this week in Pharmacy. Excited about
- 32:23Speaker 2: this next segment and just getting into news of the
- 32:28Speaker 2: day and things that are happening this week. We hope
- 32:30Speaker 2: that you've had a wonderful week in pharmacy and we
- 32:34Speaker 2: know that there's a lot of challenges in the industry
- 32:37Speaker 2: right now. We're hearing a lot from still from our
- 32:40Speaker 2: chain pharmacists. We just got to spend a lot of
- 32:43Speaker 2: time with our specialty pharmacies pharmacists out in Denver. We
- 32:49Speaker 2: attended the and the NASP be on the lookout. We're
- 32:52Speaker 2: going to be doing a three part series with the
- 32:55Speaker 2: National Association of Specialty Pharmacies. And then we're getting ready
- 33:01Speaker 2: for two conferences. We're going to be going to the
- 33:04Speaker 2: Explore event, which is Primary x's conference and their user
- 33:08Speaker 2: conference is going to be really exciting. It'll be in
- 33:10Speaker 2: New Jersey on October tenth. And then we'll also be
- 33:14Speaker 2: attending the NCPA, the National Community Pharmacist Association, the super
- 33:19Speaker 2: Bowl of all things independent community pharmacy. So I'm so
- 33:23Speaker 2: excited about that. I think that's on the twenty second
- 33:26Speaker 2: and twenty third, and we're going to have a show
- 33:29Speaker 2: probably next week or maybe the week after that. We'll
- 33:32Speaker 2: preview a little bit about what's happening, but we want
- 33:37Speaker 2: to jump back into the news quickly. I have two
- 33:40Speaker 2: special guests, and before we welcome them, I just want
- 33:44Speaker 2: to share with you news that I'm sure you're well
- 33:48Speaker 2: aware of.
- 33:51Speaker 9: First, effective immediately, the FDA will be notifying physicians at
- 33:55Speaker 9: the use of I said, well, let's see how we
- 33:59Speaker 9: say that acid of menifin acetamnifin, said okay, which is basically.
- 34:10Speaker 1: Commonly known as thailand all.
- 34:13Speaker 9: During pregnancy, can be associated with a very increased risk
- 34:20Speaker 9: of autism. So taking thailand all.
- 34:24Speaker 6: Is not good.
- 34:28Speaker 9: All right, I'll say it.
- 34:29Speaker 1: It's not good.
- 34:32Speaker 9: For this reason, they are strongly recommended that women limit
- 34:36Speaker 9: tiler will use during pregnancy unless medically necessary. That's, for instance,
- 34:43Speaker 9: in cases of extremely high fever. But you feel you
- 34:47Speaker 9: can't tough it out, you can't do it. I guess
- 34:50Speaker 9: there's that. It's a small number of cases, I think,
- 34:54Speaker 9: But if you can't tough it out, if you can't
- 34:56Speaker 9: do it, that's what you're gonna have to do. You'll
- 35:02Speaker 9: take a tile and all, but it'll be very sparingly.
- 35:08Speaker 2: So I want to welcome back Rob Cress, my godfather
- 35:12Speaker 2: of functional pharmacy, and gave you that nickname Rob quite
- 35:17Speaker 2: a while ago because you're pioneer, pioneering in the in
- 35:21Speaker 2: the world of holistic and and functional pharmacy.
- 35:25Speaker 1: And welcome back Rob.
- 35:26Speaker 5: Thank you, I appreciate it.
- 35:28Speaker 2: Another hero of mine. Lauren Castle, doctor Castle, thank you
- 35:33Speaker 2: so much for being here. It's it's great to have
- 35:35Speaker 2: you on twerks.
- 35:36Speaker 3: Absolutely thanks for having me.
- 35:39Speaker 2: All right, so I'm gonna start off with Lauren, and
- 35:43Speaker 2: I reached out to you. Thank you so much for
- 35:45Speaker 2: making this time for us at the last minute. Just
- 35:49Speaker 2: give us your your feelings about this week. In pharmacy,
- 35:53Speaker 2: where we're at and and and what you're what you're thinking.
- 35:57Speaker 3: Yeah, So as a woman, I first would have to
- 36:01Speaker 3: say that I don't think we should ever have to
- 36:03Speaker 3: just tough anything out. Unfortunately, when women's health, that sentiment
- 36:08Speaker 3: is way too commonly expressed. And so this whole discussion
- 36:13Speaker 3: really brings up an important point, which is research in
- 36:17Speaker 3: women's health, research in pregnancy, research for children. Right, normally
- 36:23Speaker 3: we're all about saying, yes, we need more of that,
- 36:25Speaker 3: But in this particular case, when the administration is actually
- 36:30Speaker 3: saying we need more of that, the established research that's
- 36:35Speaker 3: out there is pushing back and saying no, we don't
- 36:37Speaker 3: because we've already established that tilan All is supposed to
- 36:40Speaker 3: be the safest choice for pain and fever in pregnancy.
- 36:44Speaker 3: So we're getting kind of two conflicting narratives when really
- 36:49Speaker 3: the truth of the matter is it's not an either
- 36:52Speaker 3: or situation. This is a both and Right, we still
- 36:56Speaker 3: know that yes, tilan All is the safest option for
- 37:01Speaker 3: pain and fever in pregnancy, and there may be more
- 37:06Speaker 3: data that we don't fully know yet on how this
- 37:11Speaker 3: could potentially contribute to conditions that are being explored. So
- 37:18Speaker 3: if you're a mom, if you're a woman, if you're
- 37:20Speaker 3: listening to this right number one, we don't want anyone
- 37:23Speaker 3: feeling shameful about if they've used thilanol or if they're
- 37:27Speaker 3: going to need to use thailanol, because that's not the
- 37:30Speaker 3: point here where we actually are all agreeing. And I
- 37:34Speaker 3: think this is what is important to really focus in on.
- 37:39Speaker 3: Both President Trump, the FDA, and even groups like APHA
- 37:46Speaker 3: and the ACG all are saying, and I'm reading this
- 37:50Speaker 3: from the a COG website right now, judicious use at
- 37:55Speaker 3: the lowest effective dose for the shortest duration necessary in
- 38:00Speaker 3: consultation with a OBGUI or other obstetric care professional. I
- 38:06Speaker 3: would add pharmacists into that absolutely, because we know what
- 38:12Speaker 3: medications are safe or not safe for pregnant women. That's
- 38:15Speaker 3: a key part of our training, remains consistent with best practice.
- 38:20Speaker 3: That is exactly how I still feel, even using my
- 38:25Speaker 3: own functional medicine lens, the master's program that I went to.
- 38:29Speaker 3: You know, all of these things we're not disagreeing on
- 38:33Speaker 3: that a scene of menafin should be used at the
- 38:35Speaker 3: lowest effective dose for the shortest storation necessary. That's still
- 38:40Speaker 3: the bottom line. And so to me, when I think
- 38:45Speaker 3: about how I would talk to a pregnant woman who
- 38:47Speaker 3: comes to my counter and is saying, I have this headache.
- 38:52Speaker 3: You know, I'm really not sure what to take. I'm pregnant.
- 38:55Speaker 3: What should I do? A lot of pharmacists would, based
- 39:01Speaker 3: on our training, just say, oh, you can take a
- 39:04Speaker 3: tile and all, because that's the safest dose.
- 39:07Speaker 6: Right.
- 39:07Speaker 3: Don't take aspirin, don't take ibuprofen, just take a tile
- 39:10Speaker 3: and all. That will help your headache. In the functional
- 39:14Speaker 3: medicine world, the first answer is not going to be oh,
- 39:18Speaker 3: you can just take a tile and all for your headache, right,
- 39:21Speaker 3: And really, in conventional pharmacy, that also shouldn't be the
- 39:25Speaker 3: first answer.
- 39:26Speaker 5: Right.
- 39:27Speaker 3: Headache is a really common sign that something is wrong,
- 39:31Speaker 3: whether it's dehydration, electrolyte imbalance, or worse yet, an early
- 39:36Speaker 3: sign of pre ecclampsia.
- 39:38Speaker 5: Right.
- 39:38Speaker 3: If a pregnant woman comes to me and says I
- 39:40Speaker 3: have a headache, I'm taking her blood pressure immediately.
- 39:44Speaker 8: Right.
- 39:44Speaker 3: So, I think this is the most important part of
- 39:47Speaker 3: this whole conversation is that we need to be stepping
- 39:51Speaker 3: up our game as medical professionals, no matter what side
- 39:54Speaker 3: of the aisle we're on. It's really about taking care
- 39:57Speaker 3: of the patient that is in front of us at
- 40:00Speaker 3: the individual level.
- 40:01Speaker 5: Right.
- 40:02Speaker 3: Yes, we will still have tilent all as our backup
- 40:04Speaker 3: medication if we need to use it, but I would
- 40:08Speaker 3: like to see this whole conversation really push us that
- 40:11Speaker 3: much further into truly looking at the patient and looking
- 40:15Speaker 3: at all of the non pharmacologic options that we have
- 40:20Speaker 3: to treat pain, fever, headaches, all the typical things that
- 40:25Speaker 3: tailanol is used for. So that's my take on it.
- 40:29Speaker 3: I made a post on Facebook and LinkedIn, and I
- 40:32Speaker 3: was really shocked that it was shared like fifty plus times,
- 40:37Speaker 3: and by and large by women who were also saying yes,
- 40:42Speaker 3: like thank you for this. This makes so much sense. Right,
- 40:46Speaker 3: this isn't an either or situation. It's how can we
- 40:50Speaker 3: actually use these medications safely and how can we leverage
- 40:55Speaker 3: all of the other amazing potential solutions that we have
- 41:00Speaker 3: of before we get to that point of meeting medication.
- 41:03Speaker 3: And I think that's where most pharmacists stand.
- 41:06Speaker 5: I love it.
- 41:07Speaker 1: Rob Kress, my.
- 41:10Speaker 2: Functional pharmacy godfather, welcome to the show.
- 41:14Speaker 1: It's so good to have you.
- 41:16Speaker 2: Yeah, give us your input, because you and I you
- 41:18Speaker 2: you had jumped on an Instagram that I posted from
- 41:21Speaker 2: Mark Garrow fully and I always value your insights and
- 41:26Speaker 2: I if I could put a Brady Bunch panel together
- 41:30Speaker 2: today where I had like nine pharmacies all in a circle,
- 41:34Speaker 2: that would have been my preface. But it was a
- 41:36Speaker 2: blessing to get you on at the last minute. So
- 41:39Speaker 2: thanks for being here.
- 41:40Speaker 5: I appreciate it. I appreciate it, so you know, and
- 41:44Speaker 5: even regards to that, because it's funny. I'm not one
- 41:46Speaker 5: that gets traction on social media, but my god, the
- 41:49Speaker 5: last few days, so this is obviously a hot button
- 41:53Speaker 5: in a big way. So I'm grateful that the conversations
- 41:56Speaker 5: come up right. I'm glad that it was probably Bobby
- 42:00Speaker 5: Kennedy that brought this to the forefront, and I think
- 42:02Speaker 5: he did it rightfully so because I think the problem
- 42:05Speaker 5: we have in our training and in our country and
- 42:08Speaker 5: in our medical system is a casual use of over
- 42:11Speaker 5: the counter and prescription medications. Because the guidelines that Lawrence
- 42:16Speaker 5: has shared, few people practice in that, and it could
- 42:19Speaker 5: have to do with it's a busy day. We think
- 42:22Speaker 5: it's safe, but you can give it. Save we're talking
- 42:25Speaker 5: about pregnant women, you can actually give it judiciously and
- 42:28Speaker 5: someone in front of you. But what we're not talking about,
- 42:31Speaker 5: because medicine is not black and white. We live in
- 42:34Speaker 5: a big gray area. And what happens when they go home,
- 42:37Speaker 5: what happens with the use of the seed and menfin
- 42:39Speaker 5: there because we know the problem is, and this is
- 42:41Speaker 5: one thing I wanted to bring up, is it creates
- 42:44Speaker 5: a metabolite in our body that choose up this master
- 42:47Speaker 5: ani accident called gluethione. And if we want to bring
- 42:51Speaker 5: the name of autism into it, there are some studies
- 42:53Speaker 5: that will show that some autistic people do have local
- 42:57Speaker 5: dethione levels. Now there's also studies that show some don't, right,
- 43:01Speaker 5: So that's one thing. And what I had a lot
- 43:04Speaker 5: of people shoot me studies, shoot me studies, and I
- 43:07Speaker 5: want to talk about that as well, because we really
- 43:10Speaker 5: shouldn't work off of individual studies. That's the beauty of
- 43:13Speaker 5: a meta analysis, right, We're bringing a whole bunch of
- 43:16Speaker 5: people into it, and population based studies, but once again,
- 43:20Speaker 5: in every one of those, it's never your patient, so
- 43:23Speaker 5: there's so many other variables that can affect it. So
- 43:26Speaker 5: I think the importance of this thing is the conversation
- 43:29Speaker 5: came to the public. I've had a lot of people,
- 43:31Speaker 5: even on my TikTok telling me the issues that they
- 43:33Speaker 5: did have during pregnancy with talanol. So a genomic component
- 43:37Speaker 5: can come into play, right, their mitochondrial insufficiency or sufficiency
- 43:41Speaker 5: come into play. We could probably connect the dots with hypothyroidism.
- 43:45Speaker 5: So I think the important thing is not to say
- 43:48Speaker 5: it's safe, And that was my thing with your post.
- 43:51Speaker 5: I don't think anyone conclusively say that that's a generality,
- 43:55Speaker 5: but we owe it to our patients and even into
- 43:57Speaker 5: ourselves and our own individuals practice when we want to
- 44:00Speaker 5: put the patient first, to look at everything and look
- 44:03Speaker 5: at alternatives and options. Like how many people that go
- 44:06Speaker 5: to medical or pharmacy school or whatever, no one ounces
- 44:09Speaker 5: the nutrition. How many know that they can actually recommend
- 44:12Speaker 5: or learn about homeopathy which is approved by the FDA,
- 44:15Speaker 5: which can treat pain, which can treat fevers. And then
- 44:19Speaker 5: the other thing is how many people are educated on
- 44:22Speaker 5: when they really need to treat a fever. Right, A
- 44:25Speaker 5: lot of times we have a knee jerk in our society.
- 44:28Speaker 5: There's a fever, give them something, give them something, But
- 44:30Speaker 5: that fever, it has a biological purpose, and yes, it
- 44:34Speaker 5: can get too high, that can be dangerous. So I
- 44:36Speaker 5: think there's this proper education one for practitioners and to
- 44:40Speaker 5: convey that to the patients that needs to be had
- 44:43Speaker 5: as well. So I think all this brings upon a
- 44:46Speaker 5: critical you know, poles that are in our system on
- 44:50Speaker 5: how we can progress better.
- 44:54Speaker 2: So just the both of you, just to understand from
- 44:58Speaker 2: my perspective, in the in the group, you two are
- 45:02Speaker 2: the doctors. So I'm definitely going to take your advice
- 45:06Speaker 2: and take your individual device based on me compared to
- 45:10Speaker 2: someone else, right, and obviously talking with my physician, But
- 45:15Speaker 2: that's not our public today. Our public has been conditioned
- 45:21Speaker 2: to Kneeds York react. Our public has been conditioned to
- 45:27Speaker 2: take a pill for anything and everything and it just magically,
- 45:32Speaker 2: you know, is supposed to make you better. Why isn't
- 45:34Speaker 2: this working. Why isn't this you know, specific medication working.
- 45:39Speaker 2: Maybe it's because you're not eating right, or you're drinking
- 45:41Speaker 2: too many sodas or something else is happening that it's
- 45:45Speaker 2: not all about just taking a pill and being done.
- 45:48Speaker 2: And then now add in the hyper sensitivity around mixing
- 45:54Speaker 2: politics with evidence based medicine, with people who have degrees
- 45:59Speaker 2: with with the combination of but I read on Google,
- 46:04Speaker 2: or I read on TikTok for God's sakes or went
- 46:07Speaker 2: So the public is just in such a different position
- 46:12Speaker 2: than when I was growing up, where he had the
- 46:15Speaker 2: newspaper for God's sakes or a shiny looking magazine. And
- 46:19Speaker 2: now information is so quick, and then there's the world
- 46:23Speaker 2: of the chatbots, and there's the world of the clickbait,
- 46:26Speaker 2: and then there's the world of getting people's attention that
- 46:29Speaker 2: makes your jobs, Rob and Lauren so much harder. And
- 46:35Speaker 2: I can only imagine the physician after they saw this.
- 46:38Speaker 2: So my point beyond taking the the you know, the
- 46:43Speaker 2: post of a pharmacist and reposting it like I did
- 46:46Speaker 2: through Pharmacy podcast Network is and why it's so important
- 46:50Speaker 2: to have multiple input is for us to slow down
- 46:55Speaker 2: as a profession first and saying how are we going
- 46:58Speaker 2: to get ahead of this. As a matter of fact,
- 47:00Speaker 2: the APHA put out a public statement. Then it was
- 47:04Speaker 2: a blanket statement, which I in my opinion, that's a mistake.
- 47:09Speaker 2: They said right outfin's absolutely fine, this is great, blah
- 47:13Speaker 2: blah blah, and it was kind of just a black
- 47:14Speaker 2: and white statement, which is nice because you do want simplicity. However,
- 47:20Speaker 2: the both of you are semi contradicting where you're saying
- 47:25Speaker 2: it's individual and we have to really take blood pressure,
- 47:29Speaker 2: like Lawrene just said, and kind of get some factors
- 47:31Speaker 2: into what what's the headache, what's really happening, rather than
- 47:35Speaker 2: just quickly taking a pill, quickly taking something expecting that
- 47:39Speaker 2: it to be you know, okay, and then you come
- 47:41Speaker 2: you put that it's it's even more complicated because now
- 47:45Speaker 2: it's a pregnant it's it's a pregnancy and you have
- 47:47Speaker 2: another life that you're thinking about, and so wow. But
- 47:51Speaker 2: my point becoming the consumer and not the pharm d's
- 47:56Speaker 2: and certainly not the mds. As I stand back as
- 47:58Speaker 2: a I would con myself a little bit more of
- 48:01Speaker 2: a educated consumer is number one. I know how to
- 48:05Speaker 2: say a cit of minivan or hyperlipidemia or pharmacogenomics, and
- 48:09Speaker 2: it took a.
- 48:09Speaker 1: Long time to get like that.
- 48:11Speaker 2: There's the vilbon abs that I cannot get out. There's
- 48:14Speaker 2: like six or seven nab drugs. I can't say them.
- 48:18Speaker 2: But my point in my irritation was President Trump and
- 48:25Speaker 2: his administration and Bobby Kennedy.
- 48:28Speaker 1: They know what I just described.
- 48:30Speaker 2: They know that there is a heightened level of political sensitivity.
- 48:35Speaker 1: They know that no matter.
- 48:37Speaker 2: What some of the administration says, that that the opposite
- 48:42Speaker 2: of what that administration of those people like on the left,
- 48:45Speaker 2: for example, is going to just no matter what's being said,
- 48:47Speaker 2: they're going to get all upset. And so it's the
- 48:51Speaker 2: poise in the way something is being said to the
- 48:54Speaker 2: public that I have the biggest problem with, and that
- 48:57Speaker 2: is instead of being a square and pounding a square
- 49:04Speaker 2: peg in a round hole, which is President Trump's, that's
- 49:08Speaker 2: his whole He's just constantly pounding stuff, just like if
- 49:13Speaker 2: it were polished and you looked at the camera and
- 49:15Speaker 2: you're like, hey, listen. Interesting study coming out of Harvard
- 49:18Speaker 2: saying that autism could be linked could be linked in
- 49:23Speaker 2: some cases with a seed of minifin. We're going to
- 49:26Speaker 2: be looking into more of this, but we'd like to
- 49:27Speaker 2: give the public, based on h Health and Human Services,
- 49:32Speaker 2: just a warning that we really want you talking with
- 49:34Speaker 2: your pediatricians, we want you talking with your your physicians,
- 49:38Speaker 2: we want you talking with your pharmacists.
- 49:41Speaker 1: But here's what the studies, here's why we're saying this.
- 49:44Speaker 2: Rather than coming you know, at the camera and you're
- 49:47Speaker 2: just like a seed of minifin will kill you and
- 49:51Speaker 2: your baby's gonna die. Like it's just like there's just
- 49:55Speaker 2: a there's a poise that really irritated me as a
- 49:58Speaker 2: consumer and saying why did he say it like that?
- 50:02Speaker 2: To the point that everybody that hates you now hates
- 50:05Speaker 2: you even more than they hate you, and they disrespect
- 50:08Speaker 2: for you. And then the keyboard warwyors start going to
- 50:11Speaker 2: town about he's full of crap and blah blah blah,
- 50:14Speaker 2: and then now it's just creating like we didn't need
- 50:17Speaker 2: any more public distrust of health and human services or
- 50:23Speaker 2: big government or I mean, goodness, gracious.
- 50:25Speaker 1: And now now here we are. So that's my.
- 50:28Speaker 3: One todd When people watch this back, they literally should
- 50:33Speaker 3: take the sound clip of you articulating this because you
- 50:37Speaker 3: did it perfectly. You really did just now Like if
- 50:40Speaker 3: they could have just aired that clip, everyone would have
- 50:43Speaker 3: been fine. This whole thing was like definitely very politicized,
- 50:48Speaker 3: and again that that is where the harm happens, and honestly,
- 50:53Speaker 3: at the root, I think that is what all of
- 50:56Speaker 3: these different organizations are truly upset about. Right, we can
- 51:00Speaker 3: come to the table and we can have discussions, and
- 51:03Speaker 3: I do think that the letter that they came back
- 51:05Speaker 3: out with again after the fact sort of hinted to
- 51:09Speaker 3: that that this is the precautionary principle, Right, We're trying
- 51:14Speaker 3: to avoid using a scene of menaphine if it's not needed,
- 51:18Speaker 3: and maybe to their you know, in their minds, it
- 51:22Speaker 3: was being used more than it should be. We don't
- 51:25Speaker 3: really know for sure, but hopefully everyone can kind of
- 51:29Speaker 3: take a step back, take a breath, you know, and
- 51:32Speaker 3: just again try to find the middle ground in this,
- 51:35Speaker 3: which I think is where the truth really lies. You know. No,
- 51:39Speaker 3: these were not necessarily new studies that they were quoting
- 51:42Speaker 3: in this FDA article, but that doesn't mean that in
- 51:46Speaker 3: the future we won't have more studies. So I think
- 51:49Speaker 3: for us, when we're thinking through the functional medicine lens,
- 51:51Speaker 3: we're truly we're trying to understand the mechanisms behind how
- 51:55Speaker 3: this might play a role in it, even if we
- 51:58Speaker 3: don't have concrete studies suggesting beyond the shadow of a
- 52:02Speaker 3: doubt that it is. If we're thinking critically into the mechanisms,
- 52:07Speaker 3: then that's where we can say, okay, let's just use
- 52:10Speaker 3: the safest options possible. And as pharmacists, we know that
- 52:14Speaker 3: that can be non pharmacological first and then using medications
- 52:17Speaker 3: appropriately when they're actually indicated.
- 52:21Speaker 1: I love it.
- 52:22Speaker 5: Let me be the devil's advocate. Yeah, those all conversations
- 52:26Speaker 5: need that. So, you know, it's really interesting. And I
- 52:30Speaker 5: thought that because you know, eloquent he is not. And
- 52:37Speaker 5: Bobby Kennedy probably, I mean, I will say RFK Junior
- 52:42Speaker 5: is probably more well studied on medical literature than most
- 52:46Speaker 5: doctors pharmacist practitioners out there. Most people read headlines and
- 52:51Speaker 5: the abstracts. This guy dives into it. He has brought
- 52:55Speaker 5: decades of information that's already been out there to the forefront.
- 52:58Speaker 5: No one else has done that, so now he brought
- 53:01Speaker 5: it to a bullhorn. So the fact that we're in
- 53:06Speaker 5: the spot where this information has come to life, you know,
- 53:10Speaker 5: Kay Corpus and I, we don't recommend Alean on our practice.
- 53:13Speaker 5: We never have, Like it's always been off the table
- 53:16Speaker 5: unless it's absolutely necessary. But even that we seek for alternatives.
- 53:20Speaker 5: So this is not new information. Yes, these studies are old,
- 53:24Speaker 5: but they've never been shared on a large platform. Now,
- 53:28Speaker 5: as far as Trump, I was kind of wondering this
- 53:31Speaker 5: because you know, I crinsed a little bit the way
- 53:32Speaker 5: he was saying it and the results. Though I wonder
- 53:36Speaker 5: if it was like Oz talking about it, would it
- 53:40Speaker 5: have gained any attention at all? Would it have been
- 53:42Speaker 5: this nice, passive quiet letter from the FDA that any practitioner,
- 53:49Speaker 5: it's no big deal. Right, So as divisive as it
- 53:54Speaker 5: probably has been, and as there has been harm from it,
- 53:59Speaker 5: right because there's been not smart people down in a
- 54:02Speaker 5: bunch of talinol and ending up in the emergency room
- 54:05Speaker 5: who are also pregnant to try to combat that, that
- 54:08Speaker 5: is not his fault, but it does come as a
- 54:11Speaker 5: reaction to it, and I think that speaks of really
- 54:16Speaker 5: the environment that we're in, and it's been a devisive environment.
- 54:20Speaker 5: So I don't know where I sit on that, honestly,
- 54:23Speaker 5: because I don't think it would have gotten the necessary
- 54:26Speaker 5: attention that it needed because Bobby will be there in
- 54:28Speaker 5: front of Senate and he'll talk all this stuff. But
- 54:31Speaker 5: has it gone anywhere? No, Like I don't think, I mean,
- 54:35Speaker 5: you know, they talked about have be taken off of it,
- 54:37Speaker 5: thank god? Right? And if honestly, if he didn't say that,
- 54:42Speaker 5: then would people even know that, like for an infant
- 54:44Speaker 5: in a newborn So I hear what you're saying, and
- 54:48Speaker 5: it puts a hair up on most of our nex
- 54:51Speaker 5: and you know, also to speak to the point, Lauren,
- 54:54Speaker 5: You're absolutely right about people feeling shamed, and I'm I
- 55:00Speaker 5: think it's great that because no mail has a bit,
- 55:02Speaker 5: no mail can be in that position, so we can't
- 55:05Speaker 5: speak to that. And the funny thing was I talked
- 55:08Speaker 5: about that because we all have our things that we
- 55:10Speaker 5: react to and it's not to disqualify it. But you know,
- 55:13Speaker 5: lately I've been coming to face with a lot of mine,
- 55:15Speaker 5: like defensiveness, right, and the stories that I create, and
- 55:19Speaker 5: it's never that person attacking me, right, it's me and
- 55:22Speaker 5: my story. And I'm not saying that's what it is.
- 55:24Speaker 5: Could have been done in a much more eloquent way,
- 55:27Speaker 5: like I wonder if we could have brought it to
- 55:28Speaker 5: sixty percent, right, make it seem impactful in major So
- 55:33Speaker 5: it woke things up, but not so much. You know,
- 55:38Speaker 5: I don't I wouldn't want to hurt as say it.
- 55:40Speaker 5: I think it would have gone nowhere.
- 55:43Speaker 2: That's a really it's a good point of communications. And
- 55:47Speaker 2: I want to give a shout out to our pharmacists
- 55:50Speaker 2: are in our future pharmacist I'm going to be attending
- 55:53Speaker 2: my fourth time going to WVU School of Pharmacy on Monday,
- 55:59Speaker 2: and I'm gonna be spending time with pharmacy students and
- 56:02Speaker 2: it's the p threes, and I'm constantly going over the
- 56:04Speaker 2: importance of communications, social media usage, constantly writing, keeping the
- 56:10Speaker 2: writing going, keeping their opinion going, get getting themselves out there.
- 56:14Speaker 2: That communication is such a critical part of what is
- 56:22Speaker 2: trust in healthcare and who that trust is coming from,
- 56:27Speaker 2: and and how vital it is that pharmacists can be
- 56:32Speaker 2: that barometer regardless of the political surgeing of the tides
- 56:38Speaker 2: and and what's going on. And it's and that's why
- 56:41Speaker 2: I love what I do, because I feel like I
- 56:43Speaker 2: can always run to LinkedIn and putting put in a keyword,
- 56:47Speaker 2: and I have a first connection to a pharmacist that
- 56:50Speaker 2: knows exactly what sickle cell what's going on in sickle
- 56:53Speaker 2: cell disease, and what's you know, a hyper liberidemia or
- 56:55Speaker 2: something in pregnancy or something. And then you know, Lauren,
- 56:59Speaker 2: your work and and digging down into the holistic medicine
- 57:02Speaker 2: and taking your own time to build an entire association
- 57:06Speaker 2: to support other pharmacists that want to go in that direction.
- 57:09Speaker 2: And we have a whole podcast by doctor Marina Boskov
- 57:13Speaker 2: that is is nothing but holistic discussions and she goes
- 57:17Speaker 2: super nerdy, deep into the weeds. And I absolutely love
- 57:22Speaker 2: listening to pharmacists. I don't understand necessarily all of it,
- 57:25Speaker 2: but I love listening to practitioners and providers talking to
- 57:29Speaker 2: each other.
- 57:31Speaker 1: A shout out to both of you. I'm not sure
- 57:33Speaker 1: if the.
- 57:35Speaker 2: If, if the listeners know Lauren, but I want, I
- 57:39Speaker 2: want you to take a look at doctor Laurencastle dot com.
- 57:44Speaker 2: Once again, that's doctor Laurencastle dot com. That's the website
- 57:50Speaker 2: that it's gorgeous website by the way, I've I've looked
- 57:54Speaker 2: through it. I think it presents a lot of value.
- 57:58Speaker 2: We're also doing some retreats. Talk to our listeners about
- 58:01Speaker 2: some of the things that you're doing for the education
- 58:04Speaker 2: of other providers in holistic in medicine that you're working on.
- 58:09Speaker 3: Sure, So yeah, that's my personal website. The other website
- 58:13Speaker 3: you might want to check out and then I think
- 58:15Speaker 3: would be more relevant to this conversation is actually the
- 58:17Speaker 3: one listed in my little subtitle, which is FMPHA dot org.
- 58:22Speaker 3: So that's the Functional Medicine Pharmacist Alliance and that organization.
- 58:27Speaker 3: I started out as just a Facebook group back in
- 58:29Speaker 3: twenty seventeen and then we formalized our organization in twenty twenty.
- 58:33Speaker 3: We have a membership. We're an inter professional partner with
- 58:36Speaker 3: numerous functional medicine organizations, and we're also working on some
- 58:39Speaker 3: cross functional partnerships with several pharmacy organizations. But the key
- 58:44Speaker 3: thing that we offer is our Functional Medicine Pharmacists boot Camp.
- 58:47Speaker 3: So if you hear Rob and I talking about functional
- 58:49Speaker 3: medicine and you're wondering what this is and how to
- 58:51Speaker 3: specifically do it as a pharmacist, we have a ten
- 58:54Speaker 3: week program that will walk you through every step along
- 58:57Speaker 3: the way before you need to go out and spend
- 58:59Speaker 3: thousands of dollars on certifications that take numerous years to complete.
- 59:04Speaker 3: This really sets you up at the business plan from
- 59:06Speaker 3: the beginning to understand how to apply functional medicine in
- 59:09Speaker 3: pharmacy practice. So our Fall cohort is enrolling and we'll
- 59:14Speaker 3: be closing enrollment on Sunday the twenty eighth, So if
- 59:17Speaker 3: anyone is watching this this weekend and would like to
- 59:19Speaker 3: be part of it, please just reach out to us
- 59:22Speaker 3: and we'd be happy to get you started.
- 59:25Speaker 2: Thank you so much. I also want to mention Rob's environment.
- 59:30Speaker 2: I've been watching you for years. I can't believe it
- 59:32Speaker 2: makes me feel old that I can say what twelve
- 59:36Speaker 2: fifteen years ago and connecting with you and watching your
- 59:39Speaker 2: services grow and your But if you go to robcrest
- 59:43Speaker 2: dot com.
- 59:44Speaker 5: That's not it, that's not it. Functional pharmacy dot com.
- 59:48Speaker 1: Oh, functional pharmacy dot com.
- 59:50Speaker 2: You guys got to update your seos out there, Functional
- 59:54Speaker 2: pharmacy dot Com.
- 59:55Speaker 5: It was like, wow, I still have that thing out there?
- 59:58Speaker 1: You do. Yeah, it's the world of SEO. I tell
- 1:00:01Speaker 1: you what.
- 1:00:02Speaker 2: I Yeah, got out to Josh Paristini. That helps me
- 1:00:05Speaker 2: with mine and keeps us at this point. But yes,
- 1:00:10Speaker 2: just a shout out to our pharmacist. It was World
- 1:00:12Speaker 2: Pharmacist Day this week. I'm so proud of Pharmacist and
- 1:00:16Speaker 2: what they're doing on a global scale. Shout out to
- 1:00:18Speaker 2: the FIP, the Federation of International Pharmacists. I can't wait
- 1:00:22Speaker 2: to go to one of their one of their events,
- 1:00:25Speaker 2: and and you know, I just want to say thank
- 1:00:28Speaker 2: you to both of you for acting. I just just
- 1:00:30Speaker 2: for people's sake. It's it's a crazy Friday. And Lauren
- 1:00:35Speaker 2: and Rob uh Took. I text them both and got
- 1:00:38Speaker 2: them on immediately, and thank you so much for being
- 1:00:41Speaker 2: on this Week in Pharmacy to can I mention real quick?
- 1:00:44Speaker 1: Absolutely?
- 1:00:45Speaker 7: Yeah.
- 1:00:45Speaker 5: So if you go to Functional Pharmacy dot com, you
- 1:00:48Speaker 5: know I, Lauren and I work together on all this
- 1:00:50Speaker 5: and I do have a program also called Beyond the
- 1:00:53Speaker 5: Labs because if you can't tell like my thing is labstone,
- 1:00:56Speaker 5: why by they never tell the whole story. So, you know,
- 1:00:59Speaker 5: working with Farmer assist on the implementation role the coach
- 1:01:02Speaker 5: and how to really expand to implement and elevate what
- 1:01:05Speaker 5: they're doing. And the hugest passion of mine right now
- 1:01:08Speaker 5: is men's health physical, mental, emotional, spiritual of what's going
- 1:01:11Speaker 5: on there, so the Midlife Man Collective as well. I'm
- 1:01:14Speaker 5: working with male and female pharmacists one on one to
- 1:01:18Speaker 5: really step into this area of men's health that is
- 1:01:21Speaker 5: sorely needed.
- 1:01:22Speaker 1: So excellent. Thank you for that, Thank you so much
- 1:01:25Speaker 1: for that.
- 1:01:25Speaker 2: In the show notes, there's going to be the updated
- 1:01:28Speaker 2: links to both Lauren's connection as well as Rob's connection.
- 1:01:33Speaker 2: I'm also going to put in some of the LinkedIn
- 1:01:35Speaker 2: connections so that other practitioners, other providers can reach out
- 1:01:39Speaker 2: to you, Lauren and Rob.
- 1:01:41Speaker 1: Thank you so much, Thank you, Thanks Tom, all right,
- 1:01:45Speaker 1: we will.
- 1:01:53Speaker 7: This episode is sponsored by Independent Pharmacy Cooperative, widely known
- 1:01:57Speaker 7: as IPC. Established in nineteen eighty three, ip is the
- 1:02:00Speaker 7: nation's largest group purchasing organization owned by independent pharmacy with
- 1:02:05Speaker 7: a mission of maximizing the success of community pharmacists. IPC
- 1:02:09Speaker 7: works to provide members with access to effective programs and
- 1:02:12Speaker 7: services designed to enhance profitability for independent pharmacy.
- 1:02:16Speaker 1: Read more about our mission.
- 1:02:18Speaker 7: By checking out our website at ipcurx dot com. That's
- 1:02:22Speaker 7: ipcarx dot com.
- 1:02:40Speaker 2: Hey, And on this weekend pharmacy special guest, and before
- 1:02:44Speaker 2: we introduce him, there have been several instances where I
- 1:02:48Speaker 2: travel the nation for different conferences. We just got back
- 1:02:52Speaker 2: from the NASP, the National Association of Specialty Pharmacy. We
- 1:02:56Speaker 2: will have a three part series coming out. I think
- 1:02:59Speaker 2: it starts next week and there's a just packed full
- 1:03:03Speaker 2: of information and how many times the topic of how
- 1:03:06Speaker 2: will artificial intelligence be leveraged into pharmacy operations, into workflow,
- 1:03:12Speaker 2: into therapeutic data, interchange decision making, into prior authorization and
- 1:03:22Speaker 2: insurance debacles and the confusion that that can drive based
- 1:03:27Speaker 2: on some of the PBM differences and tries. And so
- 1:03:31Speaker 2: what's important to us is to constantly come back to
- 1:03:34Speaker 2: topics that we just don't think are getting enough discussion.
- 1:03:38Speaker 2: And we hear from pharmacists where they'll ask me, the
- 1:03:41Speaker 2: non pharmacist, the talking head of pharmacy, Hey, what are
- 1:03:47Speaker 2: you hearing more about sell and gene therapy and the
- 1:03:51Speaker 2: advanced studies and the advanced research. And I am lucky
- 1:03:55Speaker 2: to have this show and to have this platform because
- 1:03:58Speaker 2: we attract the best of the best in our industry.
- 1:04:00Speaker 1: And i'd like to welcome back.
- 1:04:02Speaker 2: I think this is his third time on the shows
- 1:04:05Speaker 2: and a mixture of different shows, mister Joe Dipinto with McKesson,
- 1:04:09Speaker 2: head of Cell and Gene Advanced Therapies.
- 1:04:12Speaker 1: Joe, it's so good to see you.
- 1:04:15Speaker 5: Hey, Todd, it's great to see you.
- 1:04:17Speaker 1: Thanks for having me, absolutely so.
- 1:04:19Speaker 2: Just in case people haven't heard you, you've been on
- 1:04:22Speaker 2: our Sembia shows I think twice. Tell us who you are,
- 1:04:28Speaker 2: What are you kind of overseeing through mckesson's ventures into
- 1:04:31Speaker 2: cell and gene therapy and why are you so passionate
- 1:04:34Speaker 2: about this?
- 1:04:36Speaker 6: Yeah, Todd, thanks again for having me. My name is
- 1:04:38Speaker 6: jod Depindo. I'm the head of cell gene and Advanced
- 1:04:40Speaker 6: Therapies at McKesson. I've been here now. This is just
- 1:04:44Speaker 6: celebrated my third anniversary and I joined three years ago
- 1:04:48Speaker 6: to build out the vertical for McKesson and selling gene therapy.
- 1:04:52Speaker 6: As you said, the science is so exciting here right.
- 1:04:55Speaker 6: It is game changing for patients, There's no doubt about it.
- 1:04:59Speaker 6: Our ability to un understand the human genome and cells
- 1:05:02Speaker 6: and the micro environment has produced great outcomes for patients.
- 1:05:07Speaker 6: And now how does McKesson and our vertical, which we
- 1:05:11Speaker 6: call in Spirogene help our biopharmaceutical manufacturers, providers as well
- 1:05:18Speaker 6: as payers and patients navigate the complexity of the commercial
- 1:05:22Speaker 6: value chain for selling gene. And that's what we do
- 1:05:25Speaker 6: at inspiro Gene. So that's what I've been here doing
- 1:05:28Speaker 6: the last three years. It's great to be so close
- 1:05:30Speaker 6: to this high science work and it's really fun to
- 1:05:34Speaker 6: help see patients get access to this groundbreaking technology.
- 1:05:39Speaker 2: Joe, are there any specific disease states that stick out
- 1:05:44Speaker 2: to you in the you parallel the world of specialty,
- 1:05:48Speaker 2: You parallel the world of rare disease? Is there anything
- 1:05:52Speaker 2: that sticks out to you with regards to success or
- 1:05:56Speaker 2: outcomes or studies around a specific condition.
- 1:06:00Speaker 6: You know, when I think about cell and gene advanced therapies,
- 1:06:04Speaker 6: it's still very nascent, it's in early days of these
- 1:06:07Speaker 6: this area, but it's been focused predominantly on he malignancies
- 1:06:12Speaker 6: as well as rare diseases. And that's the focus that
- 1:06:16Speaker 6: we've seen, both malignant hem and non malignant hem as
- 1:06:20Speaker 6: well as rare diseases. But what's really exciting is when
- 1:06:24Speaker 6: you look at the clinical research in the later phases
- 1:06:27Speaker 6: now going to autoimmune disease, diabetes, larger patient populations, really
- 1:06:33Speaker 6: taking a look at that research moving from clinical phases
- 1:06:37Speaker 6: to commercialization eventually, it's really important that we get it
- 1:06:41Speaker 6: right regarding the value chain in the rare disease space
- 1:06:45Speaker 6: as well as the hem malignancies in some of the
- 1:06:48Speaker 6: non malignant hem so that when these bigger indications come
- 1:06:52Speaker 6: out with a lot more patients, bigger patient population, that
- 1:06:56Speaker 6: we really understand how this all scales.
- 1:07:00Speaker 2: So just this week, if you've been paying attention out
- 1:07:04Speaker 2: there to the news wires, it says this week's Biopharma
- 1:07:08Speaker 2: news phase three trial for Parkinson's disease in cell therapy,
- 1:07:13Speaker 2: and this news is coming out of Europe and it's
- 1:07:16Speaker 2: exciting to see for what we would consider behavioral health
- 1:07:22Speaker 2: and in senior care and how that collides to pharmacists
- 1:07:27Speaker 2: understanding what that means and then where the option is,
- 1:07:31Speaker 2: and Joe explained to the listeners where that gear gets
- 1:07:35Speaker 2: shifted from a traditional pharmaceutical product to a selling gene
- 1:07:41Speaker 2: therapy product. When does the physician, pharmacist, nurse practitioner care
- 1:07:47Speaker 2: team say, hey, can we try this here?
- 1:07:51Speaker 5: You know that's you said the key word there, care team.
- 1:07:55Speaker 6: It's really important when dealing with the complexities of selling
- 1:07:59Speaker 6: gene therapy. That is just not one stakeholder here. It's
- 1:08:03Speaker 6: truly an interdisciplinary team. It can be everything from the
- 1:08:06Speaker 6: pharmacy coordinating with the cell lab, coordinating.
- 1:08:10Speaker 5: With the service line.
- 1:08:12Speaker 6: You saw Parkinson's disorder, their neurology, right, you have also oncology.
- 1:08:17Speaker 6: It's really understanding the intricacies of patient identification, appropriate patient identification, qualification,
- 1:08:25Speaker 6: benefit verification, all of that works as a team to
- 1:08:29Speaker 6: deliver these products. It's not linear. Sometimes it's circuitous in nature,
- 1:08:34Speaker 6: but it really it really is very team oriented. The
- 1:08:39Speaker 6: approach to treating these patients. So you nailed it when
- 1:08:41Speaker 6: you talk about the treatment team.
- 1:08:44Speaker 1: Yeah.
- 1:08:44Speaker 2: And as we just started before introducing you to the
- 1:08:49Speaker 2: Turks listeners, we're talking about the NASP and how many
- 1:08:53Speaker 2: times while I was there, of the thirty some guests
- 1:08:56Speaker 2: that we talked to, probably a third of them chimed
- 1:09:00Speaker 2: into artificial intelligence and how AI is being leveraged. And
- 1:09:05Speaker 2: it's not imaginary anymore. It's not what might be coming,
- 1:09:09Speaker 2: it's what's being used today. And there's an article that
- 1:09:13Speaker 2: just came out this week and it says AI transforms
- 1:09:15Speaker 2: sell in gene therapy manufacturing with real time insights. What
- 1:09:21Speaker 2: aspect of artificial intelligence are you excited about, Joe inside
- 1:09:26Speaker 2: the bucket of selling gene therapies.
- 1:09:30Speaker 6: Yeah, So what you're pointing at there is clearly a
- 1:09:33Speaker 6: barrier that has been a challenge for many manufacturers is
- 1:09:37Speaker 6: the complexity of manufacturing some of the celling gene therapies
- 1:09:40Speaker 6: and looking at how do I optimize the time to
- 1:09:43Speaker 6: delivery of these products, how do I make it more efficiently?
- 1:09:46Speaker 6: How do I get quality products to the right patient?
- 1:09:49Speaker 6: We track and we trace it appropriately, especially if it's
- 1:09:53Speaker 6: a specific autologous or matched product that needs to go
- 1:09:56Speaker 6: to that specific patient. So using technology here is a
- 1:10:00Speaker 6: common theme to overcome barriers. And look, if we're going
- 1:10:04Speaker 6: to scale the value chain and selling gene, it needs
- 1:10:07Speaker 6: to be done in a combination of intimately understanding the
- 1:10:11Speaker 6: core different components of how these products get delivered, and
- 1:10:14Speaker 6: that starts with the manufacturing process. This is not made
- 1:10:19Speaker 6: all the time the same way. If you've seen one
- 1:10:21Speaker 6: cell therapy, you've seen one cell therapy. Gene therapies get
- 1:10:24Speaker 6: made differently, right, So using technology like AI and I
- 1:10:28Speaker 6: see a lot of activity in AI, and I'm excited
- 1:10:31Speaker 6: about it, but I'm also curious to see how this
- 1:10:34Speaker 6: is going to continue to evolve, because it seems to
- 1:10:36Speaker 6: be evolving weekly.
- 1:10:39Speaker 5: At this point.
- 1:10:41Speaker 6: And look, if we can challenge, if we can overcome
- 1:10:45Speaker 6: some of the barriers to access through technology, I'm all for.
- 1:10:49Speaker 1: It, absolutely. It is.
- 1:10:51Speaker 2: It's like as scary as it is exciting sometimes when
- 1:10:54Speaker 2: you hear what AI is doing, and as long as
- 1:10:58Speaker 2: we don't lose the physicians over and the pharmacist input,
- 1:11:02Speaker 2: I'm all for it. Gene and cell cell and gene therapy.
- 1:11:06Speaker 2: I've said I'm intertwined and been corrected in previous conferences.
- 1:11:10Speaker 2: Joe so I have to be careful that the that
- 1:11:13Speaker 2: the gene comes after the cell and the if you
- 1:11:17Speaker 2: go to Google and put in cell in gene therapy McKesson,
- 1:11:23Speaker 2: you're going to pull up the very first landing page
- 1:11:25Speaker 2: is the inspirer Gene by McKesson, and it's an incredible
- 1:11:29Speaker 2: site to answer a lot of your questions if you're listening,
- 1:11:32Speaker 2: if you're wondering about specialty distribution or specially pharmacy in general,
- 1:11:37Speaker 2: and you want to just learn more about what mckesson's doing.
- 1:11:40Speaker 2: What excites you most? Let's say you said it best.
- 1:11:44Speaker 2: I mean, it's week to week that things can change, Joe.
- 1:11:47Speaker 2: But what's exciting, what's exciting, what's exciting to you being
- 1:11:52Speaker 2: part of this McKesson team as you're as you're leading
- 1:11:56Speaker 2: sellingen therapy.
- 1:11:58Speaker 5: So where I like to.
- 1:11:59Speaker 6: Think think of this time of year as the season
- 1:12:02Speaker 6: of selling gene therapy. And the reason I say that
- 1:12:05Speaker 6: is we're coming up against so many important conferences like
- 1:12:08Speaker 6: the Alliance for Regenitive Medicine that's happening in the meeting
- 1:12:12Speaker 6: on the MESA in Arizona next month, and you have
- 1:12:15Speaker 6: a lot of different value conferences around value based care
- 1:12:19Speaker 6: and selling gene therapy. So there's a lot of activity
- 1:12:22Speaker 6: in the space. The space continues to evolve as the
- 1:12:25Speaker 6: science evolves. So I'm excited about how as a industry,
- 1:12:31Speaker 6: as a cell in gene therapy ecosystem, we can all
- 1:12:34Speaker 6: get together to talk about how through cooperation collaboration, we
- 1:12:40Speaker 6: can all work together to overcome some of the complexities
- 1:12:43Speaker 6: of the value chain and complexities of patient delivery of
- 1:12:47Speaker 6: these products. Because, look, the science is unparalleled in many instances.
- 1:12:53Speaker 6: It's great to see the success scientifically. We now need
- 1:12:58Speaker 6: to start to accelerate commercial success and that can only
- 1:13:01Speaker 6: happen through collaboration of the entire ecosystem. The providers that
- 1:13:06Speaker 6: are deciding whether or not those patients get the products,
- 1:13:10Speaker 6: the sites of care where they get the products, the
- 1:13:13Speaker 6: manufacturers who are going to manufacture the product and make
- 1:13:16Speaker 6: sure it gets delivered, and the players who ultimately pay
- 1:13:18Speaker 6: for the products.
- 1:13:21Speaker 2: All Right, so we know of pharmacists who have wonderful
- 1:13:24Speaker 2: relationships with their physicians. I think of Jenna Quinn in
- 1:13:27Speaker 2: the realm of pediatrics, and she's always squawking back to
- 1:13:30Speaker 2: the pediatrician just to give them a heads up of
- 1:13:32Speaker 2: what's going on. There's going to be pharmacists out there
- 1:13:35Speaker 2: who are nerding out on sellingen therapy and really going
- 1:13:38Speaker 2: to like the advancement and the technology. What's your advice
- 1:13:42Speaker 2: to pharmacists to number one, learn more about it in
- 1:13:45Speaker 2: its application and number two, how to be more collaborative
- 1:13:49Speaker 2: with the physician leading the leading the parade.
- 1:13:53Speaker 6: You know, we talk about that a lot when we
- 1:13:56Speaker 6: think about some of the barriers for commercial adoption is
- 1:14:01Speaker 6: the referral process and when you talk to sites of
- 1:14:07Speaker 6: care as well as clinicians and pharmacists that do that well,
- 1:14:12Speaker 6: it's always about having a strong communication and referral process.
- 1:14:17Speaker 1: That it's just you.
- 1:14:18Speaker 6: Don't throw literally or figuratively throw the patient over the
- 1:14:23Speaker 6: fence and referram. It's that constant collaboration conversation around the
- 1:14:28Speaker 6: appropriate patient as a target for specific product and that
- 1:14:33Speaker 6: that patient has a good understanding as well as the pharmacist,
- 1:14:38Speaker 6: the caregiver, the whole team. Right.
- 1:14:40Speaker 5: So appropriate communication.
- 1:14:42Speaker 6: Is really important there and it helps in the referral
- 1:14:45Speaker 6: process because if you look at.
- 1:14:46Speaker 5: Some of the data and selling gene, some of.
- 1:14:49Speaker 6: These patients may not sit locally where the sites of
- 1:14:53Speaker 6: care are right, So it's important to do that. One
- 1:14:56Speaker 6: of the pieces that we've developed that in Spyrogene is
- 1:15:00Speaker 6: our Inspirrocare Hub, and that hub is a little different
- 1:15:05Speaker 6: than the typical hub. It really acts as like sort
- 1:15:08Speaker 6: of a case management component for the providers as well
- 1:15:13Speaker 6: as the patients. They're caregivers, and it helps them manage
- 1:15:17Speaker 6: the complexity of navigating patient access, everything from benefit verification
- 1:15:23Speaker 6: to a coordination of delivery of the product and communication.
- 1:15:28Speaker 6: The more transparent and communicative we can be, I think,
- 1:15:31Speaker 6: the better off everybody's experience will be.
- 1:15:36Speaker 1: Agreed.
- 1:15:36Speaker 2: If you would like to learn more, go to inspirogene
- 1:15:41Speaker 2: dot com. That's I n spiro Gene inspirogene dot com
- 1:15:47Speaker 2: by McKesson. We're going to have a link if you're driving,
- 1:15:50Speaker 2: if you're walking, you're doing something you can't see, don't worry.
- 1:15:53Speaker 2: There's going to be a link in the show notes
- 1:15:55Speaker 2: as well as a link to Joe's LinkedIn. Joe, this
- 1:16:00Speaker 2: has been wonderful. Really enjoy the insights. You're constantly giving
- 1:16:04Speaker 2: us new information. We appreciate that. Thanks for being on
- 1:16:06Speaker 2: this Week in Pharmacy.
- 1:16:08Speaker 5: Thanks tot Hey.
- 1:16:10Speaker 2: We'll be right back with more twerques in the works.