Pharma 64: Antiretroviral Therapy - Holding the Line Without Cure

Clinical Deep Dives · Feb 4, 2026 · 1m

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This episode explores HIV pharmacology as the discipline of durable containment. HIV integrates into host DNA, mutates rapidly, and rebounds when pressure slips-making cure elusive but control achievable. We trace the viral life cycle to understand why combination therapy is essential, how high genetic barriers protect efficacy, and why adherence is the…