Latest / Skin Anarchy / E.373: Jan Marini Is Back To Explain Her ICONIC Skin Care Management System!

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E.373: Jan Marini Is Back To Explain Her ICONIC Skin Care Management System! · Skin Anarchy

• 0:00
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• 0:29
  SPEAKER_03: Hey guys, welcome back.
• 0:31
  SPEAKER_03: I'm really excited about this episode because we are going to be doing an extension of Jen Ray's very popular, very well-loved masterclass series.
• 0:42
  SPEAKER_03: You guys have been so kind and chimed in about how much you've loved this series, the first five episodes, and I just thought, you know, um, why not forget about doing another five episodes and just keep going till, you know, you guys can't get enough, which I think is video gonna be the first time.
• 1:01
  SPEAKER_03: I'm super excited to announce that we will be doing another five episodes, which you're gonna end up all gonna be just as amazing as the first one.
• 1:09
  SPEAKER_03: So stay tuned for those.
• 1:11
  SPEAKER_03: This is the first one in the series, and this one is really, I think, one of the big ones, because in this episode, we're gonna learn about her skincare management system.
• 1:22
  SPEAKER_03: Now I know that you know that our top picks are coming up very, very soon, sooner than you guys realize, which I'm very excited about today.
• 1:30
  SPEAKER_03: Jan is going to be receiving what I like to say her sisters will receive our Science of Skin Award because it is truly one of the most intricate um, you know, sets that I've ever seen, a skincare set that is targeted for everyone.
• 1:49
  SPEAKER_03: For skin, for skin health.
• 1:51
  SPEAKER_03: I mean, her products and her mind literally are the closest I've ever seen to something that is, you know, custom made or just you know, skin on a molecular level.
• 2:06
  SPEAKER_03: So I don't know how to say it any differently, but it's she's just a mastermind, and I absolutely recommend this skincare management system to every single person that is so confused about skincare, you don't know where to start.
• 2:20
  SPEAKER_03: You have things like hyperpigmentation or acne or you know, you just want better-looking skin, you want to go out.
• 2:27
  SPEAKER_03: This is for everybody, and so that's why I'm advocating so hard for it.
• 2:30
  SPEAKER_03: I really think that, you know, it's it's really beautiful, which is great.
• 2:35
  SPEAKER_03: So without me ranting too much longer, I wanted to introduce this episode to you guys um with the full, you know, decorations that it deserves because it's it's truly a wonderful, wonderful episode where she uh will dive into the science of her products.
• 2:52
  SPEAKER_03: And I think that you guys should really take notes because a lot of things come up that are very, you know, not talked about, you know, not understood, I think, um well enough in not only by consumers, but even scientists and doctors.
• 3:05
  SPEAKER_03: So, yeah, take notes, do whatever you want, definitely go check out the skincare management system by Jan.
• 3:11
  SPEAKER_03: And like I said, stay tuned for top picks because there's going to be a very special special category of awards, um, which Jan is receiving one of them, but there are five total.
• 3:23
  SPEAKER_03: And these brands are truly, in my opinion, for this year, um the true hallmarks of skin health, skincare.
• 3:32
  SPEAKER_03: And so I really, really hope you guys love our topics.
• 3:35
  SPEAKER_03: I would love to hear from you all of you.
• 3:37
  SPEAKER_03: I would love for you guys to leave give us some comments, some feedback on Apple Podcasts, leave us a written review.
• 3:43
  SPEAKER_03: It helps us so, so much.
• 3:45
  SPEAKER_03: And yeah, stay tuned.
• 3:46
  SPEAKER_03: Thank you for listening.
• 3:51
  SPEAKER_03: Hi guys, welcome back to Father Anarchy.
• 3:54
  SPEAKER_03: This is Iska, and I have the wonderful Jan Marini with me again today.
• 3:58
  SPEAKER_03: And today's episode is very special because this is um, you know, for me, I've been using the system for a long time, the skincare management system.
• 4:07
  SPEAKER_03: And this episode is fully dedicated to educating all of you about the whole system and every single product in it, and as well as Jan really walking us through um, you know, the real the logic behind why she created it the way she did.
• 4:21
  SPEAKER_03: So welcome back, Jan.
• 4:22
  SPEAKER_03: I'm so excited to have you um on the show again.
• 4:25
  SPEAKER_03: I'm really, really excited to learn about this from you.
• 4:28
  SPEAKER_01: Well, thank you.
• 4:29
  SPEAKER_01: I'm excited to be here as always, and this is a fun subject, and um I'm excited to get started.
• 4:37
  SPEAKER_03: Absolutely.
• 4:38
  SPEAKER_03: And I would love to get started by just actually asking you what exactly is the skincare management system and why should we be using it?
• 4:47
  SPEAKER_01: Okay, well, I'm gonna answer it this way.
• 4:50
  SPEAKER_01: You know, when I talk to the media and they're interviewing me for the first time, and I can always predict, I know at least two of the questions they're gonna ask me.
• 4:58
  SPEAKER_01: And one is, you know, do I use my own products?
• 5:02
  SPEAKER_01: Which yes, I do.
• 5:03
  SPEAKER_01: And the second one is, you know, why do I do the research and the development?
• 5:08
  SPEAKER_01: And what inspires me to read all the medical journals and develop the products?
• 5:12
  SPEAKER_01: And I give the same answer every single time I do it because I'm selfish, and I don't want to have adult acne, and I don't want rosacea, and I don't want discoloration, and you know, I like to keep lines and wrinkles away as long as I possibly can and have relatively, you know, healthy, young-looking skin.
• 5:29
  SPEAKER_01: And so I always say, I don't want another product, I want a solution.
• 5:36
  SPEAKER_01: And that's really what the skincare management system is, is the solution.
• 5:39
  SPEAKER_01: I don't think I'm different from anyone else because the average female has over$700 in product in her bathroom, she doesn't use.
• 5:47
  SPEAKER_01: So this is the starting point for everyone.
• 5:50
  SPEAKER_01: This is it, it doesn't matter if I'm talking with a world-famous physician, if I'm talking with a huge celebrity, of which I can't tell you all the celebrities that I talk with, but I can name one of them.
• 6:03
  SPEAKER_01: And I've worked with her over the years in that share.
• 6:06
  SPEAKER_01: But they all start with the same point.
• 6:08
  SPEAKER_01: It's a skin care management system.
• 6:10
  SPEAKER_01: So that's the basis for everything.
• 6:12
  SPEAKER_01: And it really uh addresses virtually every common skin concern.
• 6:19
  SPEAKER_01: Now I look at it globally as skin rejuvenation.
• 6:22
  SPEAKER_01: And you know, most of the time when you use the term skin rejuvenation, what do people think of?
• 6:27
  SPEAKER_01: They think of fine lines and wrinkles, but uh skin rejuvenation is not just fine lines and wrinkles.
• 6:34
  SPEAKER_01: Uh for me, it's about perfecting the skin.
• 6:37
  SPEAKER_01: So it's about the appearance of rosacea or discoloration or uh all of the kinds of common skin concerns, uh, whether it's acne.
• 6:48
  SPEAKER_01: So it literally, and also fine lines and wrinkles, but it literally transforms the skin, the appearance of all of those issues.
• 6:58
  SPEAKER_01: And when somebody gets on the system and they are really seeing this uh significant change in their skin, um improvement, we also can use accelerators to even more fully address specific concerns.
• 7:19
  SPEAKER_01: And the other thing that I want to say is that when we're talking about the system, it always starts off with a critical question.
• 7:29
  SPEAKER_01: And I like every practitioner to ask this question, but you know, you could you can ask yourself this question.
• 7:36
  SPEAKER_01: If there is something you could change or improve about your skin, what would it be?
• 7:41
  SPEAKER_01: Now, normally you're going to say your first one, like maybe oh, I wish I didn't have acne, or I wish I had smaller pores, or I wish, you know, I didn't have discoloration.
• 7:51
  SPEAKER_01: So that's number one.
• 7:52
  SPEAKER_01: And then if I if you were to say, if there's something else you could change or improve about your skin, what would it be?
• 7:58
  SPEAKER_01: Typically, you're gonna come up with three or four concerns.
• 8:01
  SPEAKER_01: That's your runway.
• 8:04
  SPEAKER_01: What we want to do is we want to address every one of those concerns.
• 8:10
  SPEAKER_01: It's not about just, oh, I'm gonna buy this product because somebody says it makes your skin feel good or it has some non-specific endpoint.
• 8:18
  SPEAKER_01: You really should be using things that absolutely have the ability to address these concerns and think about how you'd feel about your skin if you were able to address every one of your concerns.
• 8:32
  SPEAKER_01: Yeah, yeah.
• 8:33
  SPEAKER_03: No, I I love that you said that because I think that that's you know, again, it kind of referenced in one of our um previous episodes, you know, it really comes down to what we should be asking.
• 8:44
  SPEAKER_03: I mean, it's it's so true, everything you said, because you know, I think a lot of consumers they don't sit down and really ask themselves.
• 8:52
  SPEAKER_03: I mean, practitioners also, but just themselves.
• 8:55
  SPEAKER_03: Like, you know, how many of you listening out there, have you ever just sat down with a journal, maybe, you know, just to make it easier and written down what you want your skin to do, you know?
• 9:06
  SPEAKER_03: And that's something that I think it really goes hand in hand with with what you said, Jan, is that this understanding of like what do I really want for my skin?
• 9:14
  SPEAKER_03: You know, is it smaller pores?
• 9:15
  SPEAKER_03: Is it less acne?
• 9:17
  SPEAKER_03: Is it you know, getting rid of the inflammation?
• 9:19
  SPEAKER_03: You have to first figure that out before you can even make a decision on where to go, you know.
• 9:23
  SPEAKER_03: So I yeah.
• 9:24
  SPEAKER_01: Ecta is and I'll tell you something along those lines.
• 9:28
  SPEAKER_01: You know, how many times have you gone for a facial?
• 9:32
  SPEAKER_01: And facials are great, and all these insert in in clinic procedures are wonderful, but somebody lays you down on a bed and they look at your skin and they proceed to tell you, well, you're this, you're that, you're dehydrated.
• 9:43
  SPEAKER_01: You know, nobody knows your skin better than you do.
• 9:49
  SPEAKER_01: Nobody has stared in the mirror at this your skin from the time you were three years old.
• 9:54
  SPEAKER_01: We all know exactly what it is that bothered us, bothers us.
• 9:58
  SPEAKER_01: We know where every little porous, we know where every little flaw is.
• 10:02
  SPEAKER_01: We just don't necessarily know what to do for it.
• 10:04
  SPEAKER_01: And that's the key.
• 10:06
  SPEAKER_01: No one else can tell you.
• 10:07
  SPEAKER_01: You everybody knows what it is that they don't like or they wish was different about their skin.
• 10:14
  SPEAKER_03: Absolutely.
• 10:14
  SPEAKER_03: No, I completely agree with you.
• 10:16
  SPEAKER_03: And I think um, you know, it's it's definitely a question that, you know, this is a more philosophical side of skincare, but it's very, very important, you know.
• 10:23
  SPEAKER_03: I completely agree with you.
• 10:24
  SPEAKER_03: People need to sit down and have this discussion with themselves and really kind of have a realization before they just go bulk by, you know, random products, you know.
• 10:33
  SPEAKER_03: Um, but I want to I want to keep uh talking about the skincare management system because I really want to learn from you, you know, um, how is it like I want you to educate our listeners on how it's possible that we could all be on the same system, but we have different concerns.
• 10:47
  SPEAKER_03: So if you could like dive into that, yeah.
• 10:49
  SPEAKER_01: That's a real common question because you know, I mean it's it's it's a logical question.
• 10:54
  SPEAKER_03: Yeah.
• 10:54
  SPEAKER_01: So somebody has acne, somebody else has fine lines and wrinkles, somebody else has discoloration.
• 10:59
  SPEAKER_01: And I'll I'll give you an example because it is designed to treat various common skin concerns.
• 11:05
  SPEAKER_01: So I'll give you an example of one product in the system.
• 11:07
  SPEAKER_01: It's called BioClear.
• 11:10
  SPEAKER_01: And some of you may be familiar with BioClear, but it's a combination of glycolic, thalicylic, and asalic acid.
• 11:18
  SPEAKER_01: Asalic acid is all by prescription for rosacea, sold by prescription for acne.
• 11:24
  SPEAKER_01: It's also one of the best resurfacing agents we've ever seen for the appearance of fine lines and wrinkles.
• 11:29
  SPEAKER_01: It's also a pigment lifting agent.
• 11:32
  SPEAKER_01: And then we have glycolic, which we could spend much, much, much time talking about glycolic, but at the very simplest level, it dissolves and dislodges the glue-like substance or cellular cement between cells.
• 11:45
  SPEAKER_01: So what it does is it causes those cells on the surface of the skin to lift apart, so it completely resurfaces the skin, and it just makes it look so much more refined and so much brighter and so much smoother.
• 12:00
  SPEAKER_01: And then because of its very small molecular weight, it's the smallest of all the alpha hydroxy acids, and it actually can get down in your follicle.
• 12:09
  SPEAKER_01: And what it does is in your follicle, there's cells lining the inside of the follicle, and it dissolves and dislodges the goo-like substance or cellular cement between those cells when they stick together.
• 12:20
  SPEAKER_01: That's the beginning of the acne process.
• 12:22
  SPEAKER_01: So it actually interrupts the acne process, and it also can help encourage collagen.
• 12:28
  SPEAKER_01: And there's, I mean, we could again, we could talk a long time on bioclear.
• 12:35
  SPEAKER_01: Yeah.
• 12:35
  SPEAKER_01: Finally, we've got salicylic acid, and we've all heard of that.
• 12:38
  SPEAKER_01: That's helpful for acne and it's helpful to make the skin look a little brighter and a little smoother.
• 12:43
  SPEAKER_01: But you put those three together, I've never seen anything for home care that has the ability to resurface and address and support so many common skin concerns.
• 12:54
  SPEAKER_01: And in the system, all of the products are have topical agents that address virtually every aspect of you know common skin concerns.
• 13:09
  SPEAKER_01: And we refer to this, or I refer to this as layered technology because you can't put everything in one product.
• 13:15
  SPEAKER_01: That's that's I have to tell you, that's a real common marketing ploy today.
• 13:20
  SPEAKER_01: Oh, gee, you can simplify your routine, just use this one product, it has glycolic in it, and it has retinol in it, and it has all of these, you know, lipoic acid and all these various topical agents.
• 13:31
  SPEAKER_01: And the fact is that here I am, I'm if I'm designing a product, I have 100% mathematically.
• 13:42
  SPEAKER_01: My ingredients add up to 100%.
• 13:44
  SPEAKER_01: They don't add up to 120 or 150.
• 13:47
  SPEAKER_01: My first 50%, 50% is or more is going to be water.
• 13:51
  SPEAKER_01: You can't bake a cake without liquid.
• 13:53
  SPEAKER_01: Then in addition to that, I have my binders and I have my spreading agents and I have stabilizing agents because you don't want to open up a product and it's just a you know a mess of separated mess.
• 14:05
  SPEAKER_01: And then I have my actives.
• 14:07
  SPEAKER_01: And what if I need 12% of something?
• 14:09
  SPEAKER_01: And I need another percentage of something else.
• 14:11
  SPEAKER_01: You you see how big these and how massive these ingredient listings are.
• 14:15
  SPEAKER_01: Well, guess what?
• 14:16
  SPEAKER_01: I run out of room.
• 14:18
  SPEAKER_01: And I could easily say, well, I'll just reduce these really critical actives, and nobody would know the difference because they would still be on the label, and I could charge you more money for them, even.
• 14:31
  SPEAKER_01: So that's one issue.
• 14:33
  SPEAKER_01: And the other issue is that many of these actives that you see together in products are not compatible.
• 14:40
  SPEAKER_01: Good example for glycolic acid to do what we know it can do medically, it needs to be at a pH of around 3.5.
• 14:50
  SPEAKER_01: Retinol needs to be at a pH of around between five and six.
• 14:53
  SPEAKER_01: Our lipid soluble C is more on the end of around seven or so.
• 14:58
  SPEAKER_01: And so you can put them together, but you're gonna render them far less active or inactive.
• 15:07
  SPEAKER_01: And I could go on and on about that.
• 15:09
  SPEAKER_01: And then when you're in the manufacturing process, some things go at a high heat, some things go at a low heat.
• 15:14
  SPEAKER_01: There's all kinds of subtleties that can decrease efficacy or just make the formulation less active.
• 15:23
  SPEAKER_01: And so that all of those things have to be addressed very, very carefully.
• 15:29
  SPEAKER_01: Um, and that's one of the reasons why we separate these actives into different products because we're able to maintain really the full efficacy and and really truly have some dynamic, dynamic results.
• 15:48
  SPEAKER_03: Yeah.
• 15:48
  SPEAKER_03: No, I mean, I love that you said that because I just want to take a minute and like really kind of hone in on the importance of what you just described.
• 15:56
  SPEAKER_03: Because I I recently wrote a little article and I'm gonna be uh eventually publishing it, but um, it was about this idea of you know how people say, Oh, well, you need an acidic pH for your skin.
• 16:07
  SPEAKER_03: And I feel like this blanket statement has taken over the industry in the worst way possible because you know, the way you're describing it is exactly how I wish more people would understand it.
• 16:18
  SPEAKER_03: Where, you know, and in that article, just to give you like an idea, what I wrote was I was talking about how your skin is not just one compartment, it's not just topical.
• 16:28
  SPEAKER_03: You know, you put 5.5 pH 5.5 on top, everything's gonna be taken care of.
• 16:32
  SPEAKER_03: No, you have intracellular, intracellular, subcellular, these are different areas and layers of your skin that need to be targeted with a different pH because the hydrogen gradients are different in those areas.
• 16:45
  SPEAKER_03: So to really combat these issues, like it's not gonna be one pH fits all.
• 16:50
  SPEAKER_03: And that's a going back to your point, Jan, where you said, you know, you can't put everything in one product because it's going to alter the overall pH of that product.
• 16:59
  SPEAKER_03: And so something that is supposed to be active at a pH of 3.5 or 4 is not going to be active if you're combining it with a pH of five.
• 17:07
  SPEAKER_03: I mean, it's going to completely render it, you know, uh useless in the formulation.
• 17:12
  SPEAKER_03: So I think this point is just so brilliant that you brought up because I I really don't think anyone people just don't think about this stuff, you know.
• 17:20
  SPEAKER_01: Well, you're true.
• 17:21
  SPEAKER_01: And then you hear this term pH balance all the time.
• 17:23
  SPEAKER_01: So my pH could be different from yours, baby's pH different from an adult.
• 17:27
  SPEAKER_01: And then the other thing is is that so you clean the skin and everybody's worried.
• 17:32
  SPEAKER_01: Well, if I'm washing my skin and it's not pH balanced, guess what?
• 17:37
  SPEAKER_01: You know, within 10 to 20 minutes after you wash your skin, it's going to go back to its normal pH anyway.
• 17:43
  SPEAKER_01: So it's it's really about the efficacy and being able to formulate.
• 17:48
  SPEAKER_01: And I you you may have heard me say this before, but it is much more difficult to formulate a really efficacious so-called cosmetic product than it is a pharmaceutical product.
• 18:02
  SPEAKER_01: Because if you and I were putting a drug through the FDA, a topical drug, we would put it in a formula and the FDA would not allow us to put a lot of other things with it because they wouldn't know whether or not we were actually getting activity from that specific drug.
• 18:18
  SPEAKER_01: And so it would be in a very simple formulation.
• 18:21
  SPEAKER_01: And they're they're basically testing it either works or it doesn't work.
• 18:25
  SPEAKER_01: Uh if I'm working with a cosmetic formulation, look at that ingredient listing.
• 18:30
  SPEAKER_01: Oh my gosh, it is so complex.
• 18:32
  SPEAKER_01: It's so multifaceted.
• 18:34
  SPEAKER_01: And you how do even chemists don't know, specifically in many instances, whether that ingredient does what it says it does or what it's going to do, because they're focused on stability, they're focused on making a product that is able to withstand um uh you know the shelf life and and and not separate.
• 18:57
  SPEAKER_01: And so it's it's really very complex.
• 19:00
  SPEAKER_03: Yes, no, absolutely.
• 19:02
  SPEAKER_03: No, I I completely agree with you, and I think that's a huge, that's a huge point.
• 19:05
  SPEAKER_03: And I feel like we should have a whole um interview on that on that alone as this idea.
• 19:10
  SPEAKER_03: It's it's very because people ask that question a lot, right?
• 19:12
  SPEAKER_03: I mean, they ask, like, well, is it FDA approved?
• 19:14
  SPEAKER_03: Is it this?
• 19:15
  SPEAKER_03: And it's like you guys don't understand there's a lot that goes into being FDA approved.
• 19:19
  SPEAKER_03: And you know, like Jen just kind of hit on the surface of that.
• 19:22
  SPEAKER_03: But yeah, I agree with you.
• 19:23
  SPEAKER_03: Um, I actually want to I want to ask you though, Jen, you know, there are five products, right, in the system.
• 19:28
  SPEAKER_03: And um, a lot of people must wonder, you know, why are there five products?
• 19:32
  SPEAKER_01: So and you know, we kind of it and that's uh again uh a really good question that it's an obvious question, and it's because um pretty much what we talked about, but I also like to think of it as it's a cleanser, which everybody has to use a cleanser, it's a sunscreen and three products in between.
• 19:49
  SPEAKER_01: Yeah.
• 19:50
  SPEAKER_01: That's pretty modest considering like in Korea the average woman uses eight plus products and so on.
• 19:58
  SPEAKER_01: Um but again, you know, it's all about being able to formulate it in a way in which you're going to maintain the the efficacy.
• 20:07
  SPEAKER_01: And um I I you know some of the things that you said were so important in terms of you know how people perceive products and also this whole thing.
• 20:19
  SPEAKER_01: I that's a question that get asked all the time.
• 20:21
  SPEAKER_01: Well, is it FDA approved?
• 20:23
  SPEAKER_01: If you go to the FDA website, there is a section for manufacturers.
• 20:28
  SPEAKER_01: And what it states in that section is that the FDA has no oversight on cosmetics unless something is misbranded or you're actually doing some kind of harm to the consumer.
• 20:39
  SPEAKER_01: And it also states that an ingredient can be either a cosmetic or a drug.
• 20:44
  SPEAKER_01: What controls whether that ingredient is a cosmetic or a drug are the claims.
• 20:50
  SPEAKER_01: So if I held up a glass of water and I said, Ecta, this glass of water will get rid of your lines and wrinkles.
• 20:57
  SPEAKER_01: Now, this that's a ridiculous statement, but the FDA would say, you know what?
• 21:00
  SPEAKER_01: That's a drug claim, and you need to do a new drug application.
• 21:04
  SPEAKER_01: And they would not allow me to market it until I can prove that claim.
• 21:07
  SPEAKER_01: Now, if I said to you, Ecta, this glass of water will get rid of the appearance of your fine lines of wrinkles.
• 21:14
  SPEAKER_01: They'd say that's a cosmetic claim, and it might be a stupid claim, but they can't stop me from making that claim.
• 21:22
  SPEAKER_01: Oh, wow.
• 21:22
  SPEAKER_01: And so individuals don't understand that.
• 21:25
  SPEAKER_01: Now, what really gives the some kind of a control over a product because cosmetic labs, so-called cosmetic labs, are not overseen by the FDA.
• 21:42
  SPEAKER_01: And keep in mind that there are thousands of cosmetic labs.
• 21:46
  SPEAKER_01: Now, what they're not allowed to do is a cosmetic lab is not allowed to make an OTC product.
• 21:51
  SPEAKER_01: Uh you know, over the counter drug would be sunscreen or benzoyl peroxide, but some of them do because how can the FDA have Enough people to go out and just inspect every one of them.
• 22:02
  SPEAKER_01: They don't inspect them.
• 22:04
  SPEAKER_01: And so that's one thing that could happen that you're not getting products that are made appropriately.
• 22:11
  SPEAKER_01: Now, what does determine FDA oversight is when a product is being made in a GMP lab that stands for good manufacturing practices.
• 22:23
  SPEAKER_01: That's a lab that has a drug license provided by the FDA.
• 22:29
  SPEAKER_01: And you cannot believe how stringent the rules are, and they're inspected all the time.
• 22:35
  SPEAKER_01: So they have the same rules as a farm.
• 22:38
  SPEAKER_01: In fact, my lab actually makes a couple of drug products, but it's a GMP lab.
• 22:44
  SPEAKER_01: And my I had a one time I took a doctor on tour of that lab, and they have we have various areas that are clean rooms.
• 22:52
  SPEAKER_01: And one of the things that she commented, she says, My God, this is better than the uh the clean the operating room of the hospital.
• 22:58
  SPEAKER_01: I could do could do surgery in here.
• 23:00
  SPEAKER_01: I mean, you cannot even begin to imagine how strict the rules are.
• 23:05
  SPEAKER_01: It can take, if somebody decides they want to become a GMP lab, they usually have to hire an FDA consultant, which my uh uh VP of my Dr.
• 23:15
  SPEAKER_01: Saxena, my VP of RD is an FDA um regulatory expert.
• 23:19
  SPEAKER_01: Um, but they usually have to do that, and it can take years to actually get to the point where they have the paperwork, they have the infrastructure to be able to even apply.
• 23:29
  SPEAKER_01: So that's one of the ways in which you know that there is some FDA oversight.
• 23:35
  SPEAKER_01: But other than that, FDA does not control our cosmetics.
• 23:38
  SPEAKER_01: And here we are, so many people are going, oh my God, I don't want to put any chemicals on my face, I don't want to do this, I don't want to do that.
• 23:44
  SPEAKER_01: And yet they're using substances that they really don't know what they're using.
• 23:50
  SPEAKER_01: And I so it's it's really important to have that insight.
• 23:53
  SPEAKER_03: Yeah, yeah.
• 23:54
  SPEAKER_03: No, I I I really agree with you, and I'm glad that you brought up the um the stringent criteria because I think that, you know, oftentimes consumers, you know, we see products that are very efficacious and we see products that are really done right, but then to understand the process of behind the scenes and you know, the world of a laboratory is extremely different than the world of making something in your kitchen.
• 24:17
  SPEAKER_03: And that's something I really hope people take away from this because, you know, uh, like you mentioned, you know, I I remember even being like a student and working in a biomedical laboratory, and they would come in and, you know, when we had our checks or you know, the people that come in for um validation and stuff, we would be reorganizing everything, cleaning everything, you know, just it was nuts.
• 24:38
  SPEAKER_03: And the process of it is so, so important because yeah, you can get flagged for the smallest things, you know, if your refrigerator is not stocked the right way, or if it's not, you know, things are not labeled the right way, like you'll get a flag.
• 24:51
  SPEAKER_03: Like these kind of things are so like in-depth detail that they look at that.
• 24:56
  SPEAKER_03: I don't think consumers um have enough appreciation for that.
• 24:59
  SPEAKER_03: So I, you know, I really give you you know, kudos for thank you.
• 25:04
  SPEAKER_01: Yeah, and the other side of that coin is that you and I we could go into our kitchen and we could say, Oh, let's come up with some organic face cream, and we could make it on our stove and we could pour it in some bottles and put a pretty label on it, and we could pay$3,000,$4,000 for a table at a medical conference, and we could put our products out there.
• 25:23
  SPEAKER_01: And I guarantee you, some physician is gonna come by and carry them in his practice.
• 25:29
  SPEAKER_01: Oh, wow.
• 25:31
  SPEAKER_01: So again, there is no oversight, and um I this is really important for consumers to understand what am I getting?
• 25:40
  SPEAKER_01: What is it actually gonna do?
• 25:41
  SPEAKER_01: Does it have any validation, etc.?
• 25:45
  SPEAKER_03: Yeah, yeah.
• 25:46
  SPEAKER_03: No, I I think this is like such an important topic.
• 25:49
  SPEAKER_03: And I really, really want us to do like a whole episode on this because it's just so there's no one knows about it, no one talks about this stuff.
• 25:56
  SPEAKER_03: Like it's like, you know, everyone's like, well, there's no oversight, but then it's like, well, where's the where, like you said, where's the flip side of this coin where we start to understand the, you know, the really meaningful components here and what brands should be striving for?
• 26:09
  SPEAKER_03: I think at this point in skincare and skin health, we should all be striving for that as a brand, you know, like the days of making something in your kitchen, I feel like that should be over.
• 26:18
  SPEAKER_01: But you know, we're we're so worried about certain aspects of whether something is is toxic or not.
• 26:26
  SPEAKER_01: You know, we're so worried about oh, if I put a sunscreen on my skin, is it going to hurt the environment?
• 26:31
  SPEAKER_01: Well, guess what?
• 26:33
  SPEAKER_01: There are a lot of people.
• 26:35
  SPEAKER_01: I just did an event recently, and one of the individuals in the audience was a dermal pathologist, and we were talking about how you have you do all these sad things in terms of biopsies and working with people that die of malignant melanoma and their faces get carved up with basal cell carcinoma and squama cell carcinoma.
• 26:55
  SPEAKER_01: You know what?
• 26:56
  SPEAKER_01: No one, no one that I know of has ever died of sunscreen.
• 27:03
  SPEAKER_01: No one.
• 27:06
  SPEAKER_01: And so what we, you know, it's really we, we, we, and the social media of TikTok and all of these various um social platforms.
• 27:17
  SPEAKER_01: I call them pseudo-intellectuals, Jan.
• 27:19
  SPEAKER_01: Yeah.
• 27:20
  SPEAKER_01: But it can be so compelling.
• 27:22
  SPEAKER_01: It can be so compelling.
• 27:23
  SPEAKER_01: Yeah.
• 27:23
  SPEAKER_01: And so um, anyway, and I know we're getting off subject, but it really is an interesting.
• 27:28
  SPEAKER_03: No, it's a very interesting, and you know, I I I could not agree with you more.
• 27:32
  SPEAKER_03: I feel like you're one of the maybe one of like three people in the world that think about this the same way I do, because I agree with you.
• 27:39
  SPEAKER_03: I think people are just it's craziness.
• 27:41
  SPEAKER_03: And sometimes I wonder why you would even believe those claims that you're gonna die from sunscreen or get cancer.
• 27:46
  SPEAKER_03: You're gonna get cancer if you don't wear sunscreen.
• 27:49
  SPEAKER_03: Let's just let's start there.
• 27:51
  SPEAKER_01: And so, really, what we should be focused on is how is the sunscreen made?
• 27:56
  SPEAKER_01: Am I buying sunscreen that's actually made in a GMP lab where you have to legally send it out to an outside agency that has is licensed to be able to then, and this is a legal issue, which you are supposed to do, but again, does everybody do it?
• 28:14
  SPEAKER_01: And what they do is they test your sunscreen so that what you're putting on there, whether it's an SPF 30 or a 40 or whatever it is, that it actually is, and that it actually goes to a certain point in the spectrum, and it actually really is, you know, water resistant.
• 28:29
  SPEAKER_01: Um, you know, those are the things I think that we really should be concerned about.
• 28:34
  SPEAKER_01: Yeah, I agree.
• 28:35
  SPEAKER_03: I think those should be the new quote TikTok trends, you know, these kind of conversations.
• 28:40
  SPEAKER_03: But let's, you know, going back to the the system, you know, I want to go through each product actually with you because the the first one is the amazing cleanser.
• 28:48
  SPEAKER_03: By the way, this is like my favorite cleanser of all time.
• 28:51
  SPEAKER_03: I am absolutely hooked on this, like literally hooked.
• 28:54
  SPEAKER_03: It's the best.
• 28:55
  SPEAKER_03: I mean, I I know there's a lot of people out there that are into the double cleanse thing, which is great for you, but I really can't find a better cleanser than this.
• 29:03
  SPEAKER_03: So um, I want you to tell us all about the bioglycolic facial cleanser.
• 29:07
  SPEAKER_03: Let's start there.
• 29:08
  SPEAKER_01: Well, thank you.
• 29:10
  SPEAKER_01: And so, one of the things I want to say about cleansers is that you can be using the best cleanser in the world.
• 29:17
  SPEAKER_01: You can double cleanse, you can triple cleanse, but cleansers aren't going to get into your follicle.
• 29:23
  SPEAKER_01: And when we cleanse our skin, what we should be concerned about is follicular cleansing because that is what is going to have the uh focus on you know how small your follicles look, and also on being able to help to prevent and and kind of break down the acne process.
• 29:44
  SPEAKER_01: Acne starts in the follicle.
• 29:45
  SPEAKER_01: So when you want skin that looks really clear and you want it to look very refined, it starts in the follicle.
• 29:52
  SPEAKER_01: I don't care how much you wash it on the outside.
• 29:55
  SPEAKER_01: So the bioglycolic facial cleanser actually has the ability to get into the follicle.
• 30:00
  SPEAKER_01: It's 12% glycolic acid.
• 30:01
  SPEAKER_01: Now, a lot of times when people hear the word glycolic acid, they think, oh my gosh, that's going to be, you know, harsh.
• 30:07
  SPEAKER_01: It's it's we may I make non-glycolic acid cleansers too, but this is the most gentle cleanser we make.
• 30:12
  SPEAKER_01: The base of it is very similar to something called cetophil.
• 30:16
  SPEAKER_01: And a lot of derms love acetophyll lotion because if you're having a reaction or your skin is really, really sensitive, then they recommend acetophil because it's such a neutral cleanser.
• 30:28
  SPEAKER_01: And so one of the things that happens as we age, and one of the things that people complain about is you look in the mirror and the outer layer of your skin, the stratum corneum, the dead layer, it starts to get very disorganized.
• 30:42
  SPEAKER_01: And how we perceive that is that those cells, instead of laying like shingles on a roof, they start to pile up and the skin looks coarser.
• 30:50
  SPEAKER_01: It doesn't look as smooth, it doesn't look as radiant, it can actually look dry when it's not really particularly dry.
• 30:55
  SPEAKER_01: And there's a term for it called increased corneocyte cohesion.
• 30:59
  SPEAKER_01: And what we want is we want a really, really thin, compact stratum cornea.
• 31:04
  SPEAKER_01: We want it to look like baby skin and just have this lovely reflective, smooth texture.
• 31:11
  SPEAKER_01: And that's really what the bioglycolic facial cleanser does.
• 31:14
  SPEAKER_01: And the reason that you love it so much, and I get this all the time, is people will say, gosh, is it my imagination?
• 31:19
  SPEAKER_01: You know, they're on day two or day three, and they're it's my imagination, but my skin looks so much smoother, it looks so much more fine.
• 31:26
  SPEAKER_01: So it's instant gratification.
• 31:29
  SPEAKER_01: This is one of the things where we can see something right away.
• 31:33
  SPEAKER_03: Yeah, absolutely.
• 31:34
  SPEAKER_03: And also what I've noticed just from me using it, I've noticed that, you know, now I've been on it for over a month now, the system for everyone listening.
• 31:42
  SPEAKER_03: And I really, really love that every single day you start you notice that glow every time you use this cleanser.
• 31:49
  SPEAKER_03: It's not just once, it's not just twice.
• 31:51
  SPEAKER_03: In the morning, when you get up and you've cleanse your skin and you get out all the stuff off from the night that you were using, your skin looks exactly what Jane just described.
• 32:00
  SPEAKER_03: It looks beautiful, glowy, renewed.
• 32:03
  SPEAKER_03: You know what I mean?
• 32:04
  SPEAKER_03: So it's just it works every time.
• 32:05
  SPEAKER_03: Every time.
• 32:07
  SPEAKER_01: Yeah, it's it's like kind of how your mouth feels when you get your teeth professionally clean because you think it gets into, you know, they get into places you just can't.
• 32:16
  SPEAKER_01: And it's like that because you are really getting into the follicle.
• 32:20
  SPEAKER_01: Um, and it makes a it makes a big difference right away.
• 32:24
  SPEAKER_01: Yeah, absolutely.
• 32:26
  SPEAKER_03: No, um, so the next product I really love is that Siesta serum.
• 32:30
  SPEAKER_03: It's beautiful, by the way.
• 32:32
  SPEAKER_03: But I love the way it smells too.
• 32:33
  SPEAKER_03: I wanted to talk to you.
• 32:35
  SPEAKER_03: Oh, I love the scent.
• 32:36
  SPEAKER_03: I love it's it's just such a it's a wonderful, wonderful product.
• 32:40
  SPEAKER_03: So I want you to uh really dive into it and the science of it.
• 32:42
  SPEAKER_01: And I and I have to tell you and our listeners about the scent in a minute.
• 32:48
  unknown: Okay.
• 32:49
  unknown: Okay.
• 32:50
  SPEAKER_01: So remind me of that.
• 32:51
  SPEAKER_01: But CS serum is a lipid soluble form of vitamin C.
• 32:56
  SPEAKER_01: Now, when we hear a vitamin C, we tend to think of ascorbic acid.
• 33:02
  SPEAKER_01: And as this is something that is not ascorbic acid, it's it's actually chemically L ascorbic acid, six palmitate.
• 33:09
  SPEAKER_01: So you remove a molecule of a lipid molecule and a let's see, it's water and alcohol, molecule of water and a molecule of alcohol, and you have the um the ester.
• 33:19
  SPEAKER_01: And the reason why that's so important is that ascorbic acid is a very, very unstable molecule.
• 33:29
  SPEAKER_01: And a lot of physicians talk about ascorbic acid in terms of redux, which means reduction and oxidation.
• 33:34
  SPEAKER_01: Um, because it's very difficult, it it causes unstability when it's used with a retinoid, it causes a lot of things and also can cause a lot of inflammation because it needs to really work, be at a pH of 2.5 or lower.
• 33:48
  SPEAKER_01: So liposoluble C, first of all, doesn't have to convert into ascorbic acid.
• 33:52
  SPEAKER_01: It's an intact molecule on its own, and it's been shown in study after study to be 30 times more potent than ascorbic acid, even if you're using one quarter of the amount, and it's completely stable, it has a two-year shelf life, it's impervious to things like oxygen or water or sunlight, all the things that break down ascorbic acid immediately.
• 34:14
  SPEAKER_01: Now, we could I could be talking with somebody who's you know considered an expert in this area, and we could go on and on about you know, sparring about the the differences between ascorbic acid and ascorbal pometate and on and on and on.
• 34:29
  SPEAKER_01: But I will tell you, if I took the vitamin C out of the ascorbal pometate, out of siesta serum, I would have an extraordinary product because of something called DMAE.
• 34:41
  SPEAKER_01: Dimethyl aminyl ethanol.
• 34:44
  SPEAKER_01: Now, dimethyl aminyl ethanol is a precursor to a major chemical messenger known as acetylcholine.
• 34:50
  SPEAKER_01: Yeah.
• 34:51
  SPEAKER_01: Now, this was actually studied in Alzheimer's disease.
• 34:55
  SPEAKER_01: This is we're going back a lot of years, but you know, at one time Alzheimer's was thought of as a disease of uh a tangled mass of neurons having to do with acetylcholine.
• 35:05
  SPEAKER_01: And we now know it has a lot to do with beta amyloid protein.
• 35:08
  SPEAKER_01: It could be type 3 diabetes, blah, blah, blah.
• 35:10
  SPEAKER_01: But at any rate, um what uh they found in this one study is that when they gave individuals a food-grade substance, DMAE, precursor to acetylcholine, that they were able to help these individuals.
• 35:26
  SPEAKER_01: It certainly wasn't a cure, but they were able to maybe help with a little bit of cognitive function and and and memory and being able to perform tasks.
• 35:34
  SPEAKER_01: And it was kind of the precursor to some of the drugs today that have been developed that sort of slow down the progression of Alzheimer's.
• 35:41
  SPEAKER_01: Again, not a cure.
• 35:43
  SPEAKER_01: Um, and they also, uh, one researcher in particular began to study the effects of acetylcholine on the skin.
• 35:52
  SPEAKER_01: Now, uh, so again, this is a major chemical messenger.
• 35:56
  SPEAKER_01: Now, every and it's every um uh nerve sparks acetylcholine into the muscle.
• 36:05
  SPEAKER_01: And one of the things that it does is it causes the muscle to kind of shorten.
• 36:09
  SPEAKER_01: We refer to that as correct anatomical muscle positioning.
• 36:12
  SPEAKER_01: You know, you could call it muscle tone, right?
• 36:15
  SPEAKER_01: And even the facial nerve sparks acetylcholine into the muscle, and it kind of helps with keeping the face more contured.
• 36:23
  SPEAKER_01: It's certainly not the only aspect of aging, but it's it's it's one of the pieces of the puzzle and makes the cheek pads stay up a little higher and the jawline look contoured.
• 36:34
  SPEAKER_01: And what happens as we age, we don't know if maybe we're producing less acetylcholine, but very possibly the receptor sites just don't pick it up the same way.
• 36:42
  SPEAKER_01: And hey, think about this.
• 36:45
  SPEAKER_01: If you exercise like a fiend when you're 60 or 65, you're still not going to have the same body from a muscular sculpted standpoint that you did when you were, you know, 20.
• 36:56
  SPEAKER_01: And so what they found is, and in the studies that they did, what they found is that, and this is a study by the way, that was presented at the American Academy of Dermatology, half-face double blind random placebo.
• 37:11
  SPEAKER_01: So on the side of the face, where they used the uh DMAE, um, they noticed that the cheek pad looked higher.
• 37:22
  SPEAKER_01: They noticed one eyebrow was higher than the other, the jawline was a little bit more defined, the neck looked better.
• 37:28
  SPEAKER_01: And compared to the other side of the face, there was a distinctive difference.
• 37:33
  SPEAKER_01: And also they found that the effect was persistent.
• 37:38
  SPEAKER_01: Now that's kind of a medical term meaning that it's not like you know, you use a skincare product that's supposed to firm your skin.
• 37:45
  SPEAKER_01: Usually those are film formers that you don't feel sticky or anything, but what they're doing is this is a film that kind of puts a little bit of pressure on the skin, makes it temporarily look firmer and lifted, but it washes off.
• 37:59
  SPEAKER_01: Well, this doesn't wash off.
• 38:01
  SPEAKER_01: In fact, in the study they found, let's just say, for an example, that you use the product for I don't know, six months, and then you decided I'm not going to use it anymore.
• 38:10
  SPEAKER_01: That you wouldn't just suddenly notice that your skin changed back, that actually if there's a permanency, the skin would age back.
• 38:22
  SPEAKER_01: And it's also one of the most powerful anti-inflammatories we found.
• 38:26
  SPEAKER_01: Um, DMAE has actually been shown to pass the brain blood barrier.
• 38:31
  SPEAKER_01: Now, not when you apply it topically, but it does have this wonderful effect on this muscle shortening at the neuromuscular junction.
• 38:38
  SPEAKER_01: And so we see that the skin just looks more conjured, it looks more lifted, and also because it's such a powerful anti-inflammatory, and aging is considered to be, you know, inflammatory in nature.
• 38:51
  SPEAKER_01: So it's just it's a phenomenal product.
• 38:54
  SPEAKER_01: And that's the that's right after you cleanse, that's the first thing that you put on.
• 38:58
  SPEAKER_01: You put it on all over your face, right up to the hairline on your neck and behind your ears.
• 39:04
  SPEAKER_03: Yeah, no, I love that you have actually brought this topic up.
• 39:08
  SPEAKER_03: Like, I feel like every time I talk to you is just for me, it's like so intellectually stimulating because like for everyone listening, Jan's like the only person that can't gets it.
• 39:17
  SPEAKER_03: Like the amount of geeking out I do over skincare and like skincare products.
• 39:21
  SPEAKER_03: Because honestly, acetylcholine, and I love that you brought up acetylcholine and the Alzheimer's connection, but acetylcholine for everyone listening also is a huge um, like basically what it does is excite your neurons.
• 39:34
  SPEAKER_03: That's what it's gonna do no matter where it is.
• 39:36
  SPEAKER_03: So, as Jan mentioned, what that is going to result in is that your vessels are actually going, it's been linked to like dilating vessels in addition to exciting the muscle.
• 39:47
  SPEAKER_03: So you're getting more blood flow to the skin, you're getting your muscles more excited.
• 39:52
  SPEAKER_03: It's like a better, in my opinion, I mean, this is a huge blanket statement.
• 39:55
  SPEAKER_03: So no one quote me on this, but it's like better than Botox, in my opinion, because you are actually physiologically stimulating receptors that already exist and just allowing them to work more.
• 40:06
  SPEAKER_03: You know, it's like the more you stimulate them, the more they're gonna fire, you know, or cause the neurons to fire.
• 40:12
  SPEAKER_03: That means it's gonna be just, you know, you're gonna be doing this, and that's where the persistence thing comes in because you're persistently activating them.
• 40:20
  SPEAKER_03: So that that makes so much sense and it's so like intuitive physiologically that I I absolutely love that.
• 40:26
  SPEAKER_03: And I love that you're using that technology.
• 40:28
  SPEAKER_03: Yeah.
• 40:29
  SPEAKER_01: I hear everybody always says the same thing you said.
• 40:31
  SPEAKER_01: They say, Oh my god, I love siesta and I love the smell.
• 40:36
  SPEAKER_01: Now, let me tell you about the smell.
• 40:37
  SPEAKER_01: Yes, yes.
• 40:39
  SPEAKER_01: So DMAE is an amine that has a natural odor that's a cross between ammonia, dead fish, and cat urine.
• 40:49
  SPEAKER_01: Now, when I was first making this product, I don't like to put fragrance in products because people have a thing about fragrance and you know they're always thinking it's gonna somehow it's the worst thing you can put in a product.
• 41:01
  SPEAKER_01: Yeah.
• 41:02
  SPEAKER_01: And um, so you know, our products for the most part are fragrance free unless I really need to put something in there.
• 41:07
  SPEAKER_01: And when I was kind of doing proof of concept on this product and doing some, you know, testing and everything, and I said to individuals, Well, tell me, if this really works, what do you think about the fact that it's doesn't have a fragrance?
• 41:18
  SPEAKER_01: Oh, we don't care, we don't care.
• 41:20
  SPEAKER_01: Well, people loved it, but they nicknamed it birth control.
• 41:26
  SPEAKER_01: So I had to come up, I had to come up with a way to scent this.
• 41:31
  SPEAKER_01: And I'm telling you, everything that I tried, what first I thought, okay, well, hey, it's siesta, you know, vitamin C oranges.
• 41:38
  SPEAKER_01: Let's let's put a nice orange scent in it.
• 41:40
  SPEAKER_01: Well, it just smelled like rotten catfish dead oranges.
• 41:45
  SPEAKER_01: So um the only thing that we came up with, and it worked so beautifully, was a natural kiwi scent.
• 41:53
  SPEAKER_01: Yeah.
• 41:54
  SPEAKER_01: And in this, and I've used the kiwi scent and other things where we needed to hide an odor or whatever.
• 42:01
  SPEAKER_01: Um, so that natural kiwi scent smells different and everything.
• 42:06
  SPEAKER_01: And in this product, for whatever reason, it just has this delicious smell.
• 42:11
  SPEAKER_01: Everybody always says you should make a perfume.
• 42:13
  SPEAKER_01: And it's just, you know, it smells like wasn't necessarily by intent, it just happened.
• 42:20
  SPEAKER_03: Well, it smells like tropical paradise, like it just smells beautiful.
• 42:24
  SPEAKER_03: Like I know that originally that wasn't the, you know, that wasn't the it smells like bananas to me.
• 42:30
  SPEAKER_03: Like it reminds me of the corners.
• 42:31
  SPEAKER_03: It doesn't.
• 42:32
  SPEAKER_03: That's interesting.
• 42:32
  SPEAKER_01: Well, I I kind of gravitate toward that type of scent, and it just to me, it just my my senses love it.
• 42:41
  SPEAKER_01: Oh, me too.
• 42:41
  SPEAKER_01: Yeah.
• 42:42
  SPEAKER_01: Everybody loves that scent.
• 42:45
  SPEAKER_01: Now, through the years, I'll tell you another inside secret.
• 42:49
  SPEAKER_01: This hasn't happened for a number of years, but every so often through the years, something would be, you know, when you work with a raw material, there is a range of what's considered to be um acceptable.
• 43:02
  SPEAKER_01: And it and it can be off by just a minuscule, and it can affect a lot of things.
• 43:07
  SPEAKER_01: And so every so often we would get breakthrough.
• 43:12
  SPEAKER_01: And some people that are very sensitive to to smells and things like that, they'd say, well, it smells like siesta, but there's an undercurrent of dead fish or ammonia.
• 43:24
  SPEAKER_01: So this has always been a challenge, but we haven't had that happen now for so long.
• 43:29
  SPEAKER_01: And I I, you know, what for whatever reason we've we've got it down pretty pat.
• 43:34
  SPEAKER_03: No, I mean, if it makes you feel better, Jen, I have I actually can't eat any fish or seafood like products because my sense of smell is so tied to my sense of taste.
• 43:45
  SPEAKER_03: And so for me, I don't smell fish at all.
• 43:48
  SPEAKER_01: So I promise you it's not.
• 43:50
  SPEAKER_01: No, we we've we've we've got it down really just great, but you never know.
• 43:54
  SPEAKER_01: You know, you never know if a manufacturer is gonna send a batch of kiwi extract that just.
• 44:00
  SPEAKER_01: Lightly off or something.
• 44:01
  SPEAKER_02: Right.
• 44:02
  SPEAKER_01: So far, so good.
• 44:04
  SPEAKER_03: Yeah, no, I I love it.
• 44:05
  SPEAKER_03: I really love it.
• 44:06
  SPEAKER_03: Now, okay, so on to the next step, BioClear.
• 44:09
  SPEAKER_03: Let's talk about BioClear.
• 44:10
  SPEAKER_03: I love this product as well.
• 44:12
  SPEAKER_01: So BioClear is the one we talked about where I said it's glycolic, salicylic, and azalic acid.
• 44:18
  SPEAKER_01: And it just has this global effect on virtually any common skin concern.
• 44:22
  SPEAKER_01: And again, it's one of that, those technologies that give you sort of that instant gratification because it has such an immediate effect on the surface of the skin.
• 44:35
  SPEAKER_01: It's also just really dramatic for again helping interrupt the acne process and helping to brighten skin.
• 44:42
  SPEAKER_01: And it thins and compacts the stratum corneum.
• 44:45
  SPEAKER_01: We want a really thin compact stratum corneum, but also glycolic thickens the dermis.
• 44:52
  SPEAKER_01: So we want thin compact stratum corneum.
• 44:54
  SPEAKER_01: We want a real thick robust dermis.
• 44:56
  SPEAKER_01: The dermis is 80% collagen, and it begins to thin right around the age of 20, maybe 1% or so a year.
• 45:05
  SPEAKER_01: But let me tell you, if you've had previous sun exposure, and that's incidental sun exposure, just growing up as a child, or if you were a sunbather, and then this the sun exposure that you have ongoing, your lifestyle, your diet, stress, all of that can cause that collagen to thin faster.
• 45:27
  SPEAKER_01: And you know, for example, a really good illustration of that is let's just say that you know, you you might think that your diet is really good, but let's say you sit down to a nice big dinner of pasta and you have some garlic bread with that, and you know, you have a vegetable, but you also have a dessert.
• 45:51
  SPEAKER_01: So what you're talking about there is a very high level of carbs and it it translates into the glycemic index, and it'll actually end up being converted into more sugar in your body than the actual amount of, let's say, the glycemic index that's there to begin with.
• 46:08
  SPEAKER_01: And what happens with these sugars is among other things, which we could spend a lot of time talking about this, but it attaches to your collagen.
• 46:17
  SPEAKER_01: Yeah, causes your collagen to stiffen, it causes it to harden, it decreases it, causes it to decrease more rapidly.
• 46:26
  SPEAKER_01: And what we found is that just limiting those kinds of factors, within two weeks, you can have a 25% decrease in your bad collagen.
• 46:40
  SPEAKER_01: And so um all those things play a role.
• 46:43
  SPEAKER_01: But what we do know is that we can substantially kind of thicken the dermis with something like, you know, we can encourage that with something like BioClear.
• 46:54
  SPEAKER_03: Yeah, yeah.
• 46:55
  SPEAKER_03: No, it's a wonderful product, actually, you know, and I I've definitely noticed, you know, because I had mentioned to everybody listening, you know, I've been on the system for more than a month now, and I literally know, like I mean, I haven't really stopped using any of the products, but I do know that the the effects that you're describing are definitely apparent in my skin because it before it was used to always be like, you know, I was very much into exfoliation and like, you know, just trying to get, but now I don't need I don't feel the need for that as much.
• 47:23
  SPEAKER_03: You know what I mean?
• 47:23
  SPEAKER_03: Like it's like you start to see this, like, you know, you're saying, for example, like the stratum corneum needs to be very, very, you know, uh thin but packed, right?
• 47:32
  SPEAKER_03: And that's when when you get to that point, I feel like you don't need to worry about, oh, I need this exfoliator or this mask or this, you know, because you don't your skin doesn't look like that anymore.
• 47:43
  SPEAKER_03: It doesn't look like it's got dead skin cells hanging off of it, you know.
• 47:47
  SPEAKER_03: So there's definitely this long-term effect that you can visibly see once you've been on the system for, you know, say a week, two weeks.
• 47:55
  SPEAKER_03: You know, I started noticing it very early.
• 47:57
  SPEAKER_03: So yeah.
• 47:58
  SPEAKER_01: You know, it really normalizes the epidermis.
• 48:01
  SPEAKER_01: And I'll give everybody kind of an example of that.
• 48:04
  SPEAKER_01: So there is a skin disease called ichthyosis.
• 48:08
  SPEAKER_03: Yeah.
• 48:09
  SPEAKER_01: Yeah, it might be congenital.
• 48:10
  SPEAKER_01: Some people are born with it, some people get it later on in life.
• 48:13
  SPEAKER_01: But literally, I've seen photos where it looks like the I you could call them the lizard person, the alligator person.
• 48:21
  SPEAKER_01: I mean that scales.
• 48:23
  SPEAKER_01: I would imagine back in the days where there were sideshows and circuses that, you know, when they advertise the lizard man, it's probably somebody with severe iclosis.
• 48:31
  SPEAKER_01: Oh, yeah, yeah, yeah.
• 48:32
  SPEAKER_01: I know what you mean.
• 48:33
  SPEAKER_01: You can you can put all kinds of lotions on that.
• 48:36
  SPEAKER_01: You can, you know, it looks like just dead dry skin.
• 48:39
  SPEAKER_01: You can soften it up, you can just, you know, you could try and scrub it off.
• 48:43
  SPEAKER_01: And it doesn't really get to the root of it at all.
• 48:47
  SPEAKER_01: And yet, you can take glycolic acid and completely change the epidermis.
• 48:56
  SPEAKER_01: Wow.
• 48:57
  SPEAKER_01: And we used to back in my company, uh MD Formulations, MD Forte, my third company, this is my fourth company.
• 49:04
  SPEAKER_01: Um, and when I pioneered this market through the um to the doctor market, pioneered glycolic acid.
• 49:12
  SPEAKER_01: And back then um it was connected with a company called Herald Pharmacol.
• 49:16
  SPEAKER_01: And one of the things that we put out, we put out a corporate folder and we showed on that corporate folder a baby with ichthyosis, the before and after, completely this the absolutely gone, and a um an older man with ichthyosis, and again, just completely, completely eliminated.
• 49:37
  SPEAKER_01: Now, that doesn't mean that I mean eliminated for good, but what we should say managed it.
• 49:42
  SPEAKER_01: And um, so it's it was really stunning.
• 49:45
  SPEAKER_01: And so, in a sense, we're epic we're we're normalizing the epidermis, and you can't do that with a scrub because a scrub, what a scrub is doing is it's basically you are manually removing supposedly dead cells, but how does the scrub know whether the cells are really dead or not?
• 50:05
  SPEAKER_01: And how do you know scrubs, even if they're small polished granules, they create inflammation and they can actually um exacerbate acne and exacerbate aspects of the aging process.
• 50:16
  SPEAKER_01: So, this is a way in which we can go beyond that and at the same time provide other elements of skin rejuvenation.
• 50:25
  SPEAKER_03: I love that.
• 50:26
  SPEAKER_03: And I love what you said about, you know, how does a scrub know, you know, if it's dead skin cells or not?
• 50:31
  SPEAKER_03: And I think that's that is such a brilliant statement, especially now because people are just you know, we always hear about it, whether it's TikTok, reels, whatever, exfoliation, exfoliation, exfoliation.
• 50:42
  SPEAKER_03: Well, you're really going to end up at a point where you're gonna have a chronic inflammatory condition if you keep doing that.
• 50:49
  SPEAKER_03: So I really you know what I mean?
• 50:52
  SPEAKER_03: So it's like, why not invest in products that will eventually make you feel like you don't have to do that anymore?
• 50:58
  SPEAKER_03: And that's why, like, I really, really love, you know, the whole system, how it progresses and how it makes your skin progress, because that's what I meant earlier, where I don't feel like I need to put a scrub on or even a chemical exfoliator.
• 51:11
  SPEAKER_03: It doesn't, that need for me is no longer there as a consumer.
• 51:14
  SPEAKER_03: And I feel like when people get to that point, that's really gonna help alleviate this process of you know chronic inflammation, which is what we see everywhere nowadays.
• 51:24
  SPEAKER_03: You know?
• 51:24
  SPEAKER_03: Yeah.
• 51:25
  SPEAKER_03: Yeah, absolutely.
• 51:27
  SPEAKER_03: So I want to talk about um the fourth step, Jan, and that's the hydration and moisturizing step.
• 51:33
  SPEAKER_03: And I really, really love again, I love your moisturizer.
• 51:36
  SPEAKER_03: So I would love for you to speak on the idea of hydration and moisture and how it really plays into the whole picture.
• 51:43
  SPEAKER_01: I use the term hydration or moisturizer because that's a term that people identify with.
• 51:48
  SPEAKER_01: It's you know, it's a common term.
• 51:50
  SPEAKER_01: And I'm gonna focus on transformation, which is in the normal combo system, and then in a dry skin system, we have a little different version, uh, which is equally as beneficial.
• 52:02
  SPEAKER_01: But really, what this is, this is a vehicle for more technology.
• 52:06
  SPEAKER_01: And at the same time, it does provide some barrier function and it does help to address you know transepidermal moisture loss and the fact that you know your barrier it can be compromised.
• 52:16
  SPEAKER_01: And but really, again, it's a vehicle for technology.
• 52:21
  SPEAKER_01: Now, to give you an example, we were the first company in the world to ever pioneer transforming growth factor beta 1.
• 52:28
  SPEAKER_01: And transferring growth factor beta 1, uh, one of the uh individuals who really did a lot of work in this area is Dr.
• 52:35
  SPEAKER_01: Weito of Jefferson University.
• 52:38
  SPEAKER_01: And what caught my attention, and this is years ago, I'm reading an article, and Dr.
• 52:43
  SPEAKER_01: Weito mentioned that transferring growth factor beta 1 stimulates a type of collagen you don't produce after the age of 30.
• 52:51
  SPEAKER_01: And then he was quoted as saying, this is just the thing to keep the skin young indefinitely.
• 52:55
  SPEAKER_01: Well, that got my attention.
• 52:57
  SPEAKER_01: And what I like to refer to this as is cytokine technology.
• 53:01
  SPEAKER_01: So cytokines are little um receptors that sit on our cells, and they're kind of like orchestra leaders, so they're constantly orchestrating collagen and orchestrating various functions.
• 53:14
  SPEAKER_01: And um this was actually pioneered originally many years ago, where they were operating on fetuses that were less than six months past conception, where they were doing things like repairing spina bifida or or even a heart defect.
• 53:29
  SPEAKER_01: And they found that these babies were born without a scar.
• 53:36
  SPEAKER_01: Now, when they really started to study this, uh, they believed that it has to do with the fact that, among other things, transferring growth factor beta 1 is produced in very high qual quantities in fetal development.
• 53:50
  SPEAKER_01: We have it, we have it in our body, we have it in receptor sites, but it it lessens significantly as we get older.
• 53:57
  SPEAKER_01: And they actually did a study where they injected a very small amount of transferring growth factor beta 1 in a wound, and it did have the effect on uh on on scarring and healing, but at the time, I think that injection was uh something like cost several hundred thousand dollars.
• 54:15
  SPEAKER_01: Now, we're not this is not in there because we think we're going to eliminate scars or we're going to have that effect.
• 54:23
  SPEAKER_01: Um, it's it's really again as an intercellular intermediary and very small amounts.
• 54:29
  SPEAKER_01: We now, I used to work actually get it from a research lab that supplied hospitals, but now we get it in the form of a peptide.
• 54:36
  SPEAKER_01: And it just has a, in my opinion, a profound effect on a lot of things that have to do with the appearance of aging.
• 54:42
  SPEAKER_01: Now, in addition to that, I also have one of my patents in there for thymus thymus and beta-4.
• 54:50
  SPEAKER_01: Thymus and beta 4 is found in every cell in the body except red blood cells.
• 54:54
  SPEAKER_01: It was actually originally discovered in the thymus of cattle.
• 54:57
  SPEAKER_01: And it's also kind of a mediator in terms of wound healing, but it's believed to help to correct instructions coming from your DNA.
• 55:06
  SPEAKER_01: And retinoids do that as well.
• 55:09
  SPEAKER_01: I like anything that helps to correct instructions coming from your DNA.
• 55:12
  SPEAKER_01: Um, and in addition, in that product, we have I actually have a select group of peptides that are proprietary to me, um, anti-inflammatories, you know, other things that are just great for barrier function.
• 55:25
  SPEAKER_01: It's a really incredibly popular product because it has such a wonderful benefit in terms of how it transforms the skin, which is why I call it transformation.
• 55:37
  SPEAKER_01: But it doesn't feel heavy.
• 55:38
  SPEAKER_01: It doesn't feel like you've got this occlusive layer on the skin in any way.
• 55:44
  SPEAKER_03: Right, right.
• 55:45
  SPEAKER_03: No, I I mean I think that that's very interesting to me about the um, you know, the growth factor idea, because I think that now we're getting to a point.
• 55:55
  SPEAKER_03: I mean, in science and obviously in in dermatology where growth factors are actually becoming like the new, like I don't I don't want to say trend, but people are like now like starting to understand that there's a lot of potential here.
• 56:09
  SPEAKER_03: And again, it goes back to signaling, right?
• 56:12
  SPEAKER_03: So it's like people are now coming to this idea of okay, well, if we have growth factors, it's going to cause our fibroblasts to do what they need to do and all this stuff.
• 56:19
  SPEAKER_03: But I mean, there is a balance, right?
• 56:21
  SPEAKER_03: There's there needs to be a balance.
• 56:23
  SPEAKER_03: So I find that to be very interesting what you said.
• 56:25
  SPEAKER_03: And in general, um, you know, with the moisturizer, I it's interesting that you put it in like that you've utilized this in the moisturizer uh category rather than like a serum.
• 56:36
  SPEAKER_01: Like, can you explain to me like actually, and actually, this is uh interesting you say that because we do make a transforming growth factor, or excuse me, we do make a transformation serum for people that maybe are a little bit more oily.
• 56:48
  SPEAKER_01: So they can use the cream or they can use the serum.
• 56:50
  SPEAKER_01: And I think that there's um some sort of a misconception about somehow serums are going to be more uh efficacious.
• 57:00
  SPEAKER_01: Um, and there's a lot of misunderstanding also about penetration.
• 57:04
  SPEAKER_01: So we tend to focus on oh my god, does it penetrate?
• 57:08
  SPEAKER_01: Does it get in far enough?
• 57:09
  SPEAKER_01: The fact is that every cell in our body has receptor sites.
• 57:12
  SPEAKER_01: And what I need to do is I need to connect in most instances with those receptor sites, and I can influence how the skin functions.
• 57:20
  SPEAKER_01: And as a matter of fact, if I were able to, in certain instances, get some type of miraculous delivery, because the skin, let me tell you, the skin is very, you know, you can spend your entire career trying to get through the skin.
• 57:34
  SPEAKER_01: If we could, if we could get through the skin easily, we'd all drown in the bathtub.
• 57:38
  SPEAKER_01: Yeah.
• 57:39
  SPEAKER_01: So I mean, this is the the one of the most efficient barriers in the history of mankind.
• 57:45
  SPEAKER_01: So um it's really about connecting with receptor sites because I can then, you know, I can stimulate collagen, I can do all of these things.
• 57:52
  SPEAKER_01: It's it's it's actually kind of fun because it's it's um um uh it's a it's a wonderful playground and it's very exciting what we're doing, and there's more and more that's happening all the time.
• 58:03
  SPEAKER_01: Now, growth factors are very large molecules, and so it's tricky when you're working with growth factors to actually get a result and their stability.
• 58:11
  SPEAKER_01: And there's some, you know, there's some nuances to that that I think we've figured out pretty well that are proprietary.
• 58:18
  SPEAKER_01: Um, but it's I I it's it's it's an extraordinary product, and um, I just kind of think it strikes the right balance in terms of what we are able to do again within this the system from a skin rejuvenation perspective.
• 58:36
  SPEAKER_03: Yeah, absolutely.
• 58:37
  SPEAKER_03: And I and I really actually see the layering aspect, you know, the more as you've gone through these steps, I'm starting to see like, you know, where that layering concept really plays in and why it is so important, you know, for everyone listening, you know, I really am a huge believer in the idea that, you know, you can't have one thing that does everything, right?
• 58:57
  SPEAKER_03: So you have to have different components that are signaling or causing signaling to occur in your cells, you know, in at different times, or even if it's at the same time, it's targeting different things.
• 59:08
  SPEAKER_03: That's very important.
• 59:09
  SPEAKER_03: There's this, you know, Jan had mentioned, you know, um, the analogy of an orchestra.
• 59:13
  SPEAKER_03: Well, if you look at an orchestra, there's different, you know, instruments, right?
• 59:17
  SPEAKER_03: And they're doing different things.
• 59:19
  SPEAKER_03: And that's exactly how cell signaling is that you have different receptors being activated that eventually will go and connect together downstream, you know, in terms of the response that they're creating.
• 59:31
  SPEAKER_03: And so that's where I find the whole system to be extremely um just fascinating, you know, from a science perspective, because it's it's really is an orchestration of multiple pathways, you know.
• 59:43
  SPEAKER_01: And so that's you also, I think you would definitely confirm this is that when you use these products, you get to the end, which we're gonna get to the last one in a moment.
• 59:55
  SPEAKER_01: But when you get to the end, you feel like oftentimes you have less product on your skin than if you were just using one moisturizer.
• 1:00:03
  SPEAKER_01: Yeah, yeah.
• 1:00:04
  SPEAKER_01: It's so lightweight.
• 1:00:05
  SPEAKER_01: That's the other thing that is just really key because you, you know, you you would think about this, you think about the sister, and you think, oh my gosh, I'm gonna feel like I have, you know, just layered all of this goop on my face.
• 1:00:20
  SPEAKER_01: And it's that's not how it works at all.
• 1:00:22
  SPEAKER_03: No, everything sinks right in, honestly.
• 1:00:24
  SPEAKER_03: Like as a consumer, I can tell, like for everyone listening, like it's it's interesting um that you bring this up, Jen, because it's very important to highlight that when you use the system, you really start to see that each product it is doing what it's doing because it's able to get into the skin and it's able to actually penetrate into layers and you feel that, you know, and just tangibly you can tell that your skin is not weighed down because the products don't sit on top of your skin like that.
• 1:00:53
  SPEAKER_03: They're not creating a film on the top of your skin at all.
• 1:00:56
  SPEAKER_03: You know?
• 1:00:57
  SPEAKER_03: So that's that's a huge, huge component that I absolutely love.
• 1:01:01
  SPEAKER_03: Um, now the final step, which is, you know, I think all of our favorites, right?
• 1:01:06
  SPEAKER_03: I want you to speak about your honestly, Jen, your sunscreens are like, you know, they're just legendary.
• 1:01:11
  SPEAKER_03: I feel like the sunscreen aspect is something you've just mastered beyond anything else I've ever seen.
• 1:01:17
  SPEAKER_03: So I would love for you to speak on this and really talk about, you know, what the technology was that went behind this.
• 1:01:23
  SPEAKER_01: Well, you know, sunscreen isn't just a cosmetic issue, it's a health issue.
• 1:01:27
  SPEAKER_01: And um I made the decision just before I turned 25 that I would start wearing a sunscreen after many years of sunbathing.
• 1:01:34
  SPEAKER_01: I'd wear one every single day, and I never ever broke my word on that.
• 1:01:41
  SPEAKER_01: And I wore them indoors, I wore them all the time.
• 1:01:45
  SPEAKER_01: And frankly, I hated them.
• 1:01:48
  SPEAKER_01: I think that I spent so much time and so much money trying to find something I'd put on my skin that didn't make me feel like I would break out, or made me break out, or was not compatible with anything else you put on the skin, or I looked greasy, or it was just went on and on.
• 1:02:04
  SPEAKER_01: And so actually, it wasn't just a matter of, you know, saying, okay, I'm gonna go and put this formula together and develop a sunscreen.
• 1:02:11
  SPEAKER_01: It was really, I'm gonna say, years and years of my own personal research and my own personal experience.
• 1:02:19
  SPEAKER_01: And I don't think I'm really different from anyone else.
• 1:02:21
  SPEAKER_01: So we make three different sunscreens, and I'm gonna talk uh for a moment about the SPF 33.
• 1:02:28
  SPEAKER_01: Now we make one that's tinted, and we make one that is a complete so-called physical block that's that's colorless.
• 1:02:37
  SPEAKER_01: The tinted is a um a physical block that's tinted, and the SPF 33 is a chemical block.
• 1:02:44
  SPEAKER_01: Now, I want to start off with telling people that a physical block is not better than a chemical block.
• 1:02:51
  SPEAKER_01: In fact, in some cases, a chemical block actually protects better.
• 1:02:55
  SPEAKER_01: And when we send these sunscreens out to the agency that everybody is supposed to send them to, where they're analyzed so that they come back to you and tell you what your SPF factor is that's been validated, and all the other attributes that you're you know allowed to say on the label, they don't know whether they are working with a chemical or a physical screen.
• 1:03:14
  SPEAKER_01: So when they assign an SPF 35 or an SPF 30 or whatever it is, that's just exactly what that product does.
• 1:03:21
  SPEAKER_01: They don't say, oh, it's an SPF 30, but it's a physical block, so it works better.
• 1:03:26
  SPEAKER_01: No, it didn't show up better in their studies.
• 1:03:28
  SPEAKER_01: So um, and and that we can we get into that that we can get into that in a lot of detail, and it can be it's more, it's much more complex.
• 1:03:36
  SPEAKER_01: But the fact is, the statistics show us that about 33 percent of Americans wear sunscreen on a consistent basis.
• 1:03:45
  SPEAKER_01: And then sometimes the numbers drop.
• 1:03:47
  SPEAKER_01: And why is that?
• 1:03:48
  SPEAKER_01: Because we're not stupid.
• 1:03:49
  SPEAKER_01: We hear all the advertising and all of the you know admonitions about sunscreen.
• 1:03:54
  SPEAKER_01: But if you talk to people and you say, Well, you know, why don't you wear them every day?
• 1:03:59
  SPEAKER_01: And you you get all kinds of answers about, well, I'm I'm not sure that it's good for the skin and blah blah blah.
• 1:04:05
  SPEAKER_01: But you know what the bottom line is?
• 1:04:06
  SPEAKER_01: Bottom line is they don't like how they feel.
• 1:04:10
  SPEAKER_01: That's behind all of it.
• 1:04:11
  SPEAKER_01: If you loved how it felt on your skin, you'd wear it.
• 1:04:14
  SPEAKER_01: So the first thing we have in the SVF 33 is we have in all of our sunscreens, by the way, we have something called an oil capture system.
• 1:04:22
  SPEAKER_01: And what this is, this is a microscopic system that has the ability to absorb almost unlimited capacities of oil, but it can't absorb the actives and it can't absorb water.
• 1:04:34
  SPEAKER_01: So it balances the skin.
• 1:04:36
  SPEAKER_01: If you had dry skin, it's gonna leave it feeling soft and silky and you know, nice and dewy.
• 1:04:41
  SPEAKER_01: And if you had more combination of early skin, it's gonna balance it out.
• 1:04:44
  SPEAKER_01: It goes both ways.
• 1:04:46
  SPEAKER_01: Yeah.
• 1:04:46
  SPEAKER_01: Um, the second thing we have in there is we have something called beta-glucan 1-3.
• 1:04:51
  SPEAKER_01: Now you have something called Lingerhorn cells.
• 1:04:53
  SPEAKER_01: And by the way, let me just stop here for a second.
• 1:04:56
  SPEAKER_01: Let's just say you're wearing what you think is the best sunscreen in the world.
• 1:04:59
  SPEAKER_01: And by the way, a difference between a 30 and a 45 or a 50 or an 80 or whatever is minuscule.
• 1:05:06
  SPEAKER_01: It doesn't really even count.
• 1:05:08
  SPEAKER_01: But you know, whatever you're wearing, you think is wonderful.
• 1:05:11
  SPEAKER_01: Um, you're still going to absorb in roughly two to three percent or more radiation.
• 1:05:17
  SPEAKER_01: That's a lot.
• 1:05:18
  SPEAKER_01: You're absorbing that into your DNA, and you are aging your skin.
• 1:05:24
  SPEAKER_01: So we have to we mitigate that.
• 1:05:26
  SPEAKER_01: Now, sunscreen is considered an over-the-counter drug, it is controlled by the FDA.
• 1:05:31
  SPEAKER_01: We talked about that.
• 1:05:32
  SPEAKER_01: So everything that we say from a drug fact standpoint is regulated.
• 1:05:38
  SPEAKER_01: Even the size of the line that goes around the drug fact box, every word, we can only state it the way the FDA allows us to state it.
• 1:05:47
  SPEAKER_01: But we can put other things in the product that we believe maybe can add or enhance that.
• 1:05:54
  SPEAKER_01: We just can't make the claims for it in terms of a sunscreen.
• 1:05:58
  SPEAKER_01: But in terms of how mitigate that radiation that gets absorbed into the skin.
• 1:06:04
  SPEAKER_01: One of the things is with something called beta-glucan 1-3.
• 1:06:07
  SPEAKER_01: Now you have Langerhan cells.
• 1:06:08
  SPEAKER_01: They look like little little curly cues or pig cells that go to the surface of the skin.
• 1:06:12
  SPEAKER_01: I didn't I meant pig tails, not pig cells, pigtails.
• 1:06:16
  SPEAKER_03: Yeah, no treat.
• 1:06:18
  SPEAKER_01: And what they do is they're kind of like your first line of defense, like little soldiers that are out there constantly on guard with coming in contact with radiation or various other things that maybe could affect the skin, compromise it.
• 1:06:33
  SPEAKER_01: But they're particularly affected by radiation and so they get compromised and they can be kind of out of commission, meaning that you are then being exposed to all of this and you don't have the same defenses.
• 1:06:44
  SPEAKER_01: So what beta glycan 1-3 is it attaches lingeron cells and it helps them from becoming compromised.
• 1:06:51
  SPEAKER_01: Second thing we have is we have something called phytomelanin.
• 1:06:54
  SPEAKER_01: Now phytomelanin is a uh comes from the date palm it's chemically identical to human melanin and we've been able to make it colorless.
• 1:07:05
  SPEAKER_01: Now the most protective element you've got in your body is your own melanin.
• 1:07:09
  SPEAKER_01: So when you see people that have really dark pigment you don't see lines and wrinkles as they get as they age because it's kind of like a built-in protection I still need to wear sunscreen but nevertheless they do have that advantage.
• 1:07:22
  SPEAKER_01: And so what this does is this is in a sense it's kind of like putting a blanket over your head because it really does add another element a protective element and so that's the SPF 33 and we have different elements similar same thing some of these same things I just said and other things as well in each of these products in each of these sunscreen products.
• 1:07:45
  SPEAKER_01: Now I'm not I'm not wearing hope nobody can see me but I'm not wearing foundation I'm not wearing tinted sunscreen or anything.
• 1:07:52
  SPEAKER_01: I do wear the tinted sunscreen once in a while because it's kind of like wearing a foundation except it's not a foundation.
• 1:07:58
  SPEAKER_01: It just makes your skin look so much pop beautifully polished and gives it kind of a nice radiant look.
• 1:08:03
  SPEAKER_01: So anyway um and that's kind of the the cherry on the cake on the system.
• 1:08:10
  SPEAKER_01: And one other thing I want to emphasize the other thing besides not feeling like you're wearing a lot of product is that it's very quick.
• 1:08:18
  SPEAKER_01: People say to me well Jan how long do I have to wait in between each step?
• 1:08:21
  SPEAKER_01: You don't just put them on.
• 1:08:23
  SPEAKER_01: Yeah yeah no I think one right after the other I don't have time to wait.
• 1:08:27
  SPEAKER_03: Right.
• 1:08:28
  SPEAKER_03: Like I mean I think that you know we we've definitely done like a deep dive into the system but that's a really important point to highlight is that you know it's you guys like for everyone listening it is this all these steps but it takes no time at all.
• 1:08:44
  SPEAKER_03: You will not feel like you are you know cutting into your morning routine or just running late for work or whatever.
• 1:08:49
  SPEAKER_03: No, it's a very quick you know process.
• 1:08:52
  SPEAKER_03: And that's what I really love about it is that you've got the science right here, you know, that we've talked about but you it's a very very quick thing that you do in the morning.
• 1:09:00
  SPEAKER_03: It's a routine and you know um I think the more important aspect right now especially when I look at you know people talking about skin health or skincare in general is establishing that routine.
• 1:09:11
  SPEAKER_03: And I really really urge everybody, you know, if you're going to establish a routine pick one thing pick one brand you know and it the whole purpose of this uh this specific segment this specific episode I think was for you guys to understand that you know the science is here you know so if you're going to pick a system pick one that's supported by science and you know really stick to it.
• 1:09:33
  SPEAKER_03: And once you stick to it for 21 days establish that habit you're automatically not going to want to divert from it.
• 1:09:39
  SPEAKER_03: That's just human nature and it also you know it kind of validates the the science behind all of Jan's products you know so I really really urge everybody you know you got to stick to it and you got to try it.
• 1:09:50
  SPEAKER_03: You know you just got to try it.
• 1:09:52
  SPEAKER_01: So well thank you.
• 1:09:55
  SPEAKER_01: And yeah the other thing is is that there is a system for combination skin which is the number one category.
• 1:10:03
  SPEAKER_01: I mean 80 85% of people you talk to yes well what type of skin do you think you have well I think it's combination.
• 1:10:10
  SPEAKER_01: And it's just a matter of you know how oily your cheese on is or how dry your cheeks are or whatever.
• 1:10:15
  SPEAKER_01: And then of course there's exceptionally oily skin and then there's skin that's really totally really dry everywhere.
• 1:10:21
  SPEAKER_01: And so um there's you know the tech the technology in each of these categories is the same.
• 1:10:28
  unknown: Yeah.
• 1:10:29
  SPEAKER_01: We don't change the technology.
• 1:10:30
  SPEAKER_01: It's just a matter of is the product that you're putting on is it maybe in a form in which there's less emolliency or there's more or oil absorption or um but it has the same technologies.
• 1:10:48
  SPEAKER_01: And so that's another thing that you see sometimes is that they're changing the technology.
• 1:10:53
  SPEAKER_01: Just because you have oily skin doesn't mean you don't need all these technologies.
• 1:10:56
  SPEAKER_01: Now there are variations as far as are there are things that we can accelerate the system with um because there are people that maybe you know they have uh acne and so we can add a product within the system we call them accelerators you know something specifically for acne something specifically for discoloration something specifically for rosacea etc so there's numerous different accelerators that can manage these conditions that have no cures.
• 1:11:27
  SPEAKER_03: We can manage it so you don't ever break out I love that totally I love that I mean I think that that's really important in the sense of like you know you don't need different ingredients just because you have different skin types you know that's really that's really really uh a big statement and I think that that's a very important concept to drive home is that you don't have to buy into the marketing hype, you know, as usual when it comes to you if you do have very dry skin it doesn't mean that you can't use a specific type of system or a specific type of product.
• 1:11:57
  SPEAKER_03: You just have to find the right kind of you know I guess balance in the formulation and that's that's very very true.
• 1:12:03
  SPEAKER_03: And you know I actually wanted to make a point Jan you know you had brought up Longerhan cells and I love that you bring that um level of science up and just for everyone listening you know since we were talking about skin cancer and we're talking about sunscreens, you know, fun fact is you know longer hand Longerhan cells are actually your your resident macrophages in your skin.
• 1:12:23
  SPEAKER_03: And what macrophages are they're going to eat up all of the you know like dead debris and the stuff you don't want sitting around.
• 1:12:30
  SPEAKER_03: So they're really really important cells to target you know and they're really important cells to study.
• 1:12:35
  SPEAKER_03: And so if you've got a brand that's already you know Jan's already ahead of the game here you know we're talking about things that are very very high tech and they're um you know in terms of science it's a very science forward way of thinking you know and you want that because the skin like we all know it's a very dynamic organ.
• 1:12:52
  SPEAKER_03: It's something that we don't know very much about you know I often say the brain and the skin is very similar.
• 1:12:58
  SPEAKER_03: We know just as much about the skin as we do the brain you know it's very stomach stomach brain and skin.
• 1:13:04
  SPEAKER_03: Yeah yeah those three development that's one of the the uh areas where they they you know that develop the together when you look at the the quadrants and in the and fetal development um but anyway yeah yeah no absolutely and you know that's why it's it's just so important to you know what we do know stick to those facts you know don't don't try to come up with solutions that are not science backed you know that's really I think my message here for people listening that you know you you gotta trust the experts here you really do you know you just like you wouldn't go to a cardiologist to get your brain tumor fixed or you know handled or whatever you wouldn't go to a you know what I mean you wouldn't go to somebody a housewife in their kitchen to get your skin fixed right so that's the idea and I really urge everybody you know look into the science and really you know trust it like you have to you have to trust it.
• 1:13:56
  SPEAKER_03: So um Jan that brings me to my last question for you and that's really um about what are you know what are things that we can do to accelerate the system you know if now that we've bought it you know we're using it um you know what if we want to address specific concerns or we want to accelerate the progress that we're seeing what are some things that we can add on um that so I sort of the top ones and there's there's lots of things that we can do but some of the top ones acne is an epidemic among women in their 20s 30s 40s 50s 60s and beyond some people say well I don't break out I you know I don't have acne just break out once in a while well whether you break out once a day once a month 10 times a day it's the same process and if you have clogged follicles if you have blackheads that's non-inflammatory acne is still acne so duality is really a revolutionary uh topical that is able to actually de-age the appearance of skin and address acne at the same time get complete total clearing another one of my top issues uh I should say not me personally but in general when you hear from people is that everybody by the age of 35, if you've got skin, every person on the face of the earth will have abnormal discoloration.
• 1:15:08
  SPEAKER_01: And if you don't have obvious areas of contrasting discoloration you'll have what's called background pigment also known asinic bronzing and so that's a huge issue.
• 1:15:17
  SPEAKER_01: And again there's no cure for it but we can manage it.
• 1:15:21
  SPEAKER_01: We can dramatically manage it.
• 1:15:23
  SPEAKER_01: One of the fastest growing skin conditions today is rosacea it affects over 16 million Americans but I will tell you that number is underreported because unless you go to a derm and somebody reports it there are many more people than that that have rosacea and um we know that characteristically when we look at rosacea it it it it it exhibits itself with um redness and flushing and blushing and the appearance of telange which are dilated capillaries no cure for rosacea we can manage it we also have things you know to further manage the appearance of fine lines and wrinkles and loss of volume because 50% of what we perceive of aging is loss of volume people say to me all the time gee I you know I looked in the mirror and it looked like somebody took the air out of my face um so uh there are just so many different things that you can do and even you know things that you can do supplementally that speed up the process of whatever you're trying to accomplish dramatically um things you do a couple of times a week where you can do like our our peel pads um the multi-acid uh resurfacing pads or the multi-acid corrective pads jar that has 30 pads in it that are moistened with um a combination of acids and some other technology that dramatically continue to resurface the skin speed up the process or help with acne discoloration post-inflammatory hyperpigmentation help with the appearance of acne scarring which is an injury to the dermis the discoloration is not a scar um and you know also uh I mean I gotta tell you I'm working on I'm working on a lot of new technology right now I'm having a you know I go through periods where sometimes I feel creatively dry and then other times I come across things in journals and I think wow uh they're just I'm I'm having a renaissance right now so I love that yes I love that no you're it's like you know when the creative uh creative uh spirit is there you know you just gotta you gotta go with it.
• 1:17:28
  SPEAKER_03: I love that I mean I I really you know I love the way that you approach skin health overall Jen I think that you know there's a lot of uh notes that someone can take from your book you know and the overall approach you know I I often see brands that are you know they and I'm sure you've noticed this is they're targeting one thing you know and or they get stuck up on one molecule or one ingredient and it becomes this hallmark and I just I'm so anti that you know it's like it it just goes against everything I believe in as a physiologist, as a doctor everything like I don't believe in that.
• 1:18:02
  SPEAKER_03: I I think that you know if you have a brand that's just advertising retinol and that's all they do that you need to rethink that because there's a lot more you know like we said we've talked about in this entire episode there's a lot more that goes into this overall homeostasis of your skin and then also the recovery process from you know inflammatory conditions like acne and rosacea which you mentioned earlier.
• 1:18:24
  SPEAKER_01: So I'm a huge fan you know of the your process and the way you got we are singing off the same sheet of music because you know so many times you hear about something like oh there's this German scientist and he came up with this molecule years ago that was for wound healing and now he's put it in the skincare product and every skincare product you know that he makes has this molecule in there it's supposed to dramatically address everything.
• 1:18:46
  SPEAKER_01: Well guess what?
• 1:18:47
  SPEAKER_01: Yeah you know you're using that molecule you still have acne maybe your skin looks maybe your skin does look a little smoother but you're still using it and you you know you still have large follicles and et cetera et cetera it it's it's really about addressing all those concerns.
• 1:19:01
  SPEAKER_01: And I think one of the things that um I'm kind of focusing on more and more is the things that we have been very successful at in being able to truly address acne and kind of transform the skin and make it look so much smoother and you know just younger and better.
• 1:19:20
  SPEAKER_01: But really getting into from a topicals perspective um how we can turn on things like sertoins which are antagones.
• 1:19:30
  SPEAKER_01: We have roughly 24 of them and you know there's um when we talk about correcting instructions coming from our DNA which is really what is kind of at the root of the perception of aging when we see fine lines and wrinkles it's it's this blueprint the instructions that our skins the only thing that they look at the only thing our body looks at to repair achieve normalcy and they get scratched they get compromised and so we don't repair the same way.
• 1:19:55
  SPEAKER_01: Well being able to correct those instructions but going beyond that there's an interesting um kind of paradigm uh going on out there right now where uh it's believed that in a sense these instructions and and our epigeome and etc are like a computer hard drive and that we may actually have a completely pristine backup computer hard drive that we might be able to reboot.
• 1:20:23
  SPEAKER_01: Yeah and and you know maybe every year every two years we reboot it and so we look at this in terms of not necessarily I mean longevity would be great but we look at it as health span or skin health span in terms of regardless of how long we're going to live are we going to live it in a vibrant healthy way and are we going to look like we're not decaying and so when we talk about anti-aging that's kind of a a thing today where people have they they look at that negatively say you know you don't want to use that term because it's it's judgmental etc no it's not I'll tell you why because aging is considered a disease now how can it be a disease if it affects more than 50% of the people because the disease is defined as affecting less than 50% like cancer or heart disease or whatever.
• 1:21:16
  SPEAKER_01: Well guess what what is aging made up of it's made up of all kinds of diseases and so we are really on the cusp of being able to address these diseases and and and it's going to affect our skin and being able to decode a lot of this um I think it's a lot a lot of the things that I'm working on at the moment and um I think I've got pretty good handle on a couple of these things.
• 1:21:42
  SPEAKER_03: So yeah no I mean I I think you've you've got a good handle on a lot of different things with skin honestly you you really are the guru for skin health I really mean that you know it's it's very for me as a scientist it's very um encouraging to to hear when you speak about the the true you know nature of your products and why you're using them the way you are why you're formulating the way you are because I you know like I said I every single day I come across brands, influencers, whoever it is that's speaking about skin health but they have absolutely no idea what the hell they're talking about.
• 1:22:18
  SPEAKER_03: And it's so irritating to sit there and listen because a part of me is like oh my gosh I wish I could just stop you and just correct like the 15 things you've said you know in the last 10 minutes.
• 1:22:29
  SPEAKER_03: So it's for me it's always a breath of fresh air Jan every time we speak because it you really are you know brilliant.
• 1:22:36
  SPEAKER_01: Well it's thank you so much.
• 1:22:37
  SPEAKER_01: That's so kind of you but you know it is frustrating because when you have the competitive rhetoric out there and it's not just the fact that you know somebody's not buying your product it's the fact that they're being misled and thinking that somehow this product really has stem cells in it.
• 1:22:56
  SPEAKER_01: Yes or yeah you know that you know I mean you you know there's a there there's a medical study that was done where they took a paraplegic and I don't know how many years ago this was with paraplegic that was paralyzed completely paralyzed and over working two years in terms of the area of stem cells they were able to get this person to literally stand up with the help of braces and actually take a few steps completely you know with braces everywhere now with that said they got the stem cells from this person's nose and the complexity of of what they were able to achieve is beyond my even my comprehension.
• 1:23:44
  SPEAKER_01: But to think that you could take something that you think is a stem cell that's so delicate it is so prone to anything and stick it in with a whole bunch of other ingredients right and then put heat and centrifuge it and then somehow or exosomes for that matter somehow you're gonna have this activity or better yet plant stem cells because we know oh my god we know that we can mate with a plant right yeah absolutely you know I plan on having like oak babies soon so it's okay you know I just it's it's really about I really am passionate about wanting to provide that education so that people really are using things because our skin is so connected to our self-esteem.
• 1:24:34
  SPEAKER_01: It is our skin it's so um you know important that individuals feel um really good about what they see in the mirror.
• 1:24:47
  SPEAKER_03: Exactly and you know it's it really does tie into so many things and you know we discussed like you know the gut brain skin idea but that's a that's the real axis.
• 1:24:57
  SPEAKER_03: I mean for everyone who doesn't believe that I I I really challenge you to prove us wrong because it's a real axis.
• 1:25:04
  SPEAKER_03: I mean it's a whole area of study that's ongoing and it's very very interesting how it's working and and going to your point about stem cells Jen I could not agree with you more.
• 1:25:13
  SPEAKER_03: Oh my gosh like I remember like three years ago I wrote a little mini blog piece on this I was like stem cells will not survive in a jar that you ship to wherever the hell you're going stem cells like for anyone who's ever worked in a lab to even grow them in a petri dish and to get them to like divide and then split those cells and have those cultures be viable enough to then re you know what I mean pull out of uh liquid nitrogen and use again that by itself is you know 75% of the time it fails.
• 1:25:47
  SPEAKER_03: So to have them in actual products and then make people believe that they're working in some way it's just it's absurdity and I don't get it.
• 1:25:56
  SPEAKER_03: I just don't know how consumers buy into this stuff.
• 1:25:58
  SPEAKER_01: That's what really gets me you know the closest we've come to skin cells in terms of skin rejuvenation is when you do fat transfer because fat's full of stem cells and it re-educates the cells around it so it can make them look younger.
• 1:26:12
  SPEAKER_01: But it also depends on where you get the fat from and doctors know that when they're doing this and they don't necessarily have a million dollar machine sitting in their office that how many of them are viable or what you're actually getting in as the end result is is very unpredictable.
• 1:26:27
  SPEAKER_01: I have a friend that works at well it's part she has ownership in a company in Switzerland that actually does a lot of this mainly into China and where they do stem cells work with it but they actually have a machine that can count them and they know exactly what it is they're delivering and but it's oh it's so complex and it's so expensive and it's just it's crazy.
• 1:26:52
  SPEAKER_03: It's a lot no it's a lot it the stem cell research is not cheap at all.
• 1:26:55
  SPEAKER_03: Yeah absolutely I mean it it's a lot of uh and you know here's the thing I would actually love to see maybe one day you know Jane you'll come up with thing because stem cells actually secrete a lot of things that are helpful in terms of turning on the cells nearby like you mentioned so if we're going to talk about stem cells for anyone out there who's creating a brand and you're about to do this please take it off your label let's reassess okay and and and and by the way you know um we we now know that you don't need fetal stem cells to actually do these things where you can you can create this rejuvenation um and you don't you you you can take adult cells and you can have these effects but we're not certainly not where we can stick it in the skincare product or anything like that.
• 1:27:39
  SPEAKER_03: No absolutely not and I I don't even think we would need it to be I'm I'm curious to see if we would even need them you know in skin health like that's another top it's just like you know the application of science like I feel like people need to understand everything that's discovered doesn't apply to every organ.
• 1:27:56
  SPEAKER_03: You know that's it's like a huge thing.
• 1:27:58
  SPEAKER_03: Like just because it's works for your liver or your brain or your gut doesn't mean it's going to work for your skin.
• 1:28:04
  SPEAKER_03: So you know we have to really come to an understanding, I think, as a consumer base and just people in general, you know, that scientists they they discover things, but that doesn't mean that's the holy grail of now fixing all of the problems on the planet.
• 1:28:16
  SPEAKER_03: You know, it's it's a very, very complex protocol that goes behind actually creating something from discovery, you know, and applying it.
• 1:28:25
  SPEAKER_01: And I have a motto and that is it's there's a difference between what you can do and what you should do.
• 1:28:31
  SPEAKER_03: Yes.
• 1:28:31
  SPEAKER_03: Oh wow.
• 1:28:32
  SPEAKER_03: Yeah.
• 1:28:32
  SPEAKER_03: Absolutely.
• 1:28:33
  SPEAKER_03: 100%.
• 1:28:34
  SPEAKER_03: I completely agree with you.
• 1:28:35
  SPEAKER_03: And I think, you know, if people really actually stuck, you know, that should be the motto of all skincare beauty industry, please, because we have so many products now and I and I just get so scared.
• 1:28:46
  SPEAKER_03: I I really do, Jan.
• 1:28:47
  SPEAKER_03: I get scared.
• 1:28:48
  SPEAKER_03: I look at the I look at the brands coming out every day and I'm like, I wonder how many different kinds of problems this is going to create, you know, from a medical standpoint.
• 1:28:58
  SPEAKER_03: How many derms out there, you know, are going to be frustrated with absolutely new skin conditions emerging, you know, and more problems and more inflammation.
• 1:29:07
  SPEAKER_03: So yeah, I mean I could rant for this about this for hours with you, but this has been so fun.
• 1:29:12
  SPEAKER_03: And I love that we really dove in I love that we dove into the system because you know I'm a huge fan.
• 1:29:17
  SPEAKER_03: I've been using it like I said for everyone listening, I really encourage you, you know, um go check out the system, you know, on the website.
• 1:29:25
  SPEAKER_03: And then obviously, you know, if you want to do a consultation, if you want to learn more about it, you know, there's definitely resources available.
• 1:29:32
  SPEAKER_03: You know, so definitely take advantage of that and learn about your skin.
• 1:29:37
  SPEAKER_03: Learn about your skin, you guys, you know, it's it's an organ and it's something that requires really thought out well thought out researched you know ingredients.
• 1:29:47
  SPEAKER_03: And that's exactly why Jan and I are doing this segment because we want you to understand that the science in her products is revolutionary and I really urge all of you to check it out.
• 1:29:56
  SPEAKER_01: So thank you so much Jan and it's all as always it's been a pleasure and thank you everybody who's listening because I wouldn't be here without you and thank you so much Ecta till next time.
• 1:30:07
  SPEAKER_03: Till next time absolutely okay hey guys so I hope you love that episode.
• 1:30:15
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• 1:30:20
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• 1:30:44
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• 1:30:58
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• 1:31:08
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• 1:31:15
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• 1:31:20
  SPEAKER_03: Thank you.