Latest / Skin Anarchy / MaryAnn GuerraAesthetics Biomedical®President and Chief Executive Officer

Transcript

MaryAnn GuerraAesthetics Biomedical®President and Chief Executive Officer · Skin Anarchy

• 0:00
  SPEAKER_00: Okay.
• 0:01
  SPEAKER_00: Hey guys.
• 0:01
  SPEAKER_00: So our next guest is Mary Ann Guerr.
• 0:04
  SPEAKER_00: She is the CEO and president of Aesthetics Biomedical and has an immense and very impressive background in in really helping brands come up with FDA clear technology and treatment serums.
• 0:17
  SPEAKER_00: And um Ms.
• 0:18
  SPEAKER_00: Guerra has also had a very impressive career at the NIH.
• 0:22
  SPEAKER_00: And she has held senior level positions such as executive officer and also at the National Heart and Lung, Heart, Lung and Blood Institute, and Deputy Director of Management and Executive Officer at the National Cancer Institute.
• 0:35
  SPEAKER_00: So that's, you know, just a little glimpse of her background.
• 0:38
  SPEAKER_00: But welcome to the show, uh, Marianne.
• 0:40
  SPEAKER_00: I'm so excited you had the time.
• 0:42
  SPEAKER_01: Well, it's a pleasure to be here and talking to you and uh being able to uh share some information with your uh your uh viewers and uh the folks listening to this.
• 0:53
  SPEAKER_01: So um thank you very much.
• 0:54
  SPEAKER_00: Yeah, it's my pleasure.
• 0:56
  SPEAKER_00: I would love it if you could tell us more about your your career and um you know just dive deeper because I know I just skimmed the surface.
• 1:03
  SPEAKER_01: Well, thanks for giving me an opportunity to do that because I think um my my career has really fashioned where we are today with the company.
• 1:13
  SPEAKER_01: Um and you know, every time you have a job, whether it's a good job or a bad job, an experience, it's a good experience or a bad experience, you learn from it, right?
• 1:21
  SPEAKER_01: And you take it and you say, Oh, I'm gonna do that again and build on it, or I'll never do that again, and this is how how I will avoid that.
• 1:27
  SPEAKER_01: And so um I was really lucky when I got started to work with the the NAS, the NIH um really early on in my career.
• 1:36
  SPEAKER_01: Um and um I I started with the Cancer Institute.
• 1:40
  SPEAKER_01: Um, and uh when I was there, um I worked with the medical oncology branch and just really got a feel for you know treating patients and the importance of science and you know the impact on families when they don't um whether a loved one is faced with these horrible diseases.
• 1:57
  SPEAKER_01: And then um I got a chance to um I was recruited then to the National Institute of Allergy and Infectious Diseases, and that was probably um a really extraordinary time in my career because I worked with uh Dr.
• 2:12
  SPEAKER_01: Anthony Fauci.
• 2:13
  SPEAKER_01: Um, and Tony at that time was uh both a lab chief, um the chief of the laboratory of immune regulation as well as the director of the NIAID.
• 2:22
  SPEAKER_01: And as most of us know, he still is.
• 2:24
  SPEAKER_01: Um he's great, but when I was there, it was um AIDS.
• 2:29
  SPEAKER_01: We were just faced with the AIDS dilemma, and what are we going to do about that?
• 2:33
  SPEAKER_01: And people didn't know about the virus, they didn't know how it was transmitted, and you know, the panic that is facing us with COVID was the exact same thing, and there were no drugs, and there were, you know, so um it was so interesting to be there, but allergy to infectious diseases also is an institute that is developing vaccines for all kinds of things.
• 2:54
  SPEAKER_01: So hepatitis B, dengue virus, um uh chlamydia.
• 2:59
  SPEAKER_01: So when I was there, um I really got into technology transfer because it became really important if you if you have new knowledge, which you're doing at NIH or NIH funded programs, and you create this new information, but you don't transfer that to pharma companies or to entrepreneurs who create businesses and then create products, then it's a waste of taxpayers' money and and research, right?
• 3:26
  SPEAKER_01: So yeah, yeah.
• 3:28
  SPEAKER_01: And I got into this how do we have those better connections?
• 3:31
  SPEAKER_01: How do we uh forge these partnerships with industry to make that happen?
• 3:35
  SPEAKER_01: And so um I have to say, while I was at um NIAID, we forged uh quite a few relationships with industry and we got the chlamydia vaccine out, the respiratory system virus vaccine out, hepatitis B, all kinds of things.
• 3:49
  SPEAKER_01: So it was really rewarding to see that you know, great science leads to incredibly important products.
• 3:56
  SPEAKER_01: And, you know, of course, we had major um, you know, uh accomplishments in the AIDS field as well.
• 4:02
  SPEAKER_01: And then you know, then I went on to Heart, Lung, and Blood, which was doing amazing things in the cardiovascular area.
• 4:08
  SPEAKER_01: You know, that was the number one uh killer in the United States at that point in time, probably still is, um, you know, and then went back to the NCI.
• 4:17
  SPEAKER_01: And um when I was at NCI, I again took this tech transfer um mentality with me.
• 4:25
  SPEAKER_01: Um and we really uh started again forge the relationships that we needed with industry.
• 4:31
  SPEAKER_01: And once I left NIH, um, you know, I kept that and went and worked with an organization in in Phoenix.
• 4:39
  SPEAKER_01: That's how I ended up in Phoenix called the Translational Genomics Research Institute.
• 4:43
  SPEAKER_01: And that was and that's personalized medicine.
• 4:46
  SPEAKER_01: What we had just mapped the human genome at NIH, right?
• 4:48
  SPEAKER_01: You know, so all this genetic information you and you know, they were getting the point where everybody could, you know, map their own human genome, their own genome.
• 4:58
  SPEAKER_01: And so personalized medicine really came into play.
• 5:01
  SPEAKER_01: It's like, okay, you know, what's your what's your genomic uh profile?
• 5:05
  SPEAKER_01: How do we get a drug that goes against that profile?
• 5:08
  SPEAKER_01: You know, how do we, you know, and and interestingly enough, if you have a profile, you know, you'll hear patients say, well, this drug worked on this cancer patient, but you know, this drug didn't work on this cancer patient.
• 5:21
  SPEAKER_01: You know, why?
• 5:22
  SPEAKER_01: Well, they had different genomic profiles, you know.
• 5:25
  SPEAKER_01: And so the the exciting thing is how do you match those?
• 5:28
  SPEAKER_01: How do you get the right drug with the right profile?
• 5:30
  SPEAKER_01: And it's a it's a whole new field.
• 5:32
  SPEAKER_01: And I think that's it leads me to like, you know, where we are now with the company I formed.
• 5:36
  SPEAKER_01: I I worked um with a bunch of startup companies, um, ran a nonprofit, founded a nonprofit called BioExcel.
• 5:42
  SPEAKER_01: Um, and the whole idea was how do we accelerate that transfer of information from universities, um, from research and start companies.
• 5:52
  SPEAKER_01: And yeah, yeah, I love that.
• 5:54
  SPEAKER_00: By the way, can I just say, like, you're the person I've been looking for since I started this podcast?
• 5:59
  SPEAKER_00: Because then what you're addressing is exactly the questions I've had is that how do we get academia involved with the corporate world?
• 6:09
  SPEAKER_00: You know what I mean?
• 6:09
  SPEAKER_00: And it's like, like, because there's so much data that's being generated, or there's so much knowledge and just, you know, that that's out there in the medical community.
• 6:17
  SPEAKER_00: But it when it comes to um just you know, consumers and and brands that are coming out that don't have a medical background, it's almost as if it's like they're, you know, people are living in this age where they think that medical discovery isn't there, but it is, you know what I mean?
• 6:31
  SPEAKER_00: And so to get that translated over to where it's being applied on a mass, you know, like mass market level, like that's been always my one of my biggest questions.
• 6:42
  SPEAKER_01: Yeah, you know, it's a it's a complicated situation, right?
• 6:46
  SPEAKER_01: Because um, when we work with startup companies, it's so hard, right?
• 6:51
  SPEAKER_01: So you um if you talk to scientists, every discovery that they have is the next best thing, right?
• 6:57
  SPEAKER_01: It's gonna be, you know, it's what everybody wants, the market wants it, you know, and you know, and it's actually not that way.
• 7:04
  SPEAKER_01: It's you know, it's very few great discoveries that are great science, but they aren't great products, right?
• 7:10
  SPEAKER_01: And so first you have to narrow down, you know, what is what is a great product, what is a great discovery, but which is a great discovery that's actually important in terms of developing a product that's going to benefit society or benefit an industry, et cetera.
• 7:26
  SPEAKER_01: So you got to have that betting process, and that's hard because a lot of you know the wrong things get funded and the and the right things don't.
• 7:34
  SPEAKER_01: Um, you know, and then there's so many risks.
• 7:37
  SPEAKER_01: So if you're in the biomedical community, you know, now you've got this great product, and then you have you, you know, you look up at your horizon and you got regulatory obstacles, and you have intellectual property obstacles, and you have all of these things that you know are could be crushing to a startup company.
• 7:52
  SPEAKER_01: Um, you know, the bottom line is I I think that um science is really important, you know, and so you know, you have to look at, you know, what supports these new products, what supports um like in the aesthetic industry, you know, what I tried to bring to the company is a more rigorous approach to when we promote something, let's do it.
• 8:14
  SPEAKER_01: It either has to have the science or we need to do more science behind it.
• 8:18
  SPEAKER_01: Um we need to share that with the public.
• 8:21
  SPEAKER_01: Um, and so we've tried um very hard to do more science and then to have that science published because again, you we're living in a world where you know there are people questioning whether they should get the COVID vaccine, you know.
• 8:34
  SPEAKER_01: Yeah, yeah.
• 8:36
  SPEAKER_01: Questioning science.
• 8:37
  SPEAKER_01: And you know, um it you you have to say, okay, I question, you know, but um when you see data and you see enough data, then you should feel comfortable that that data supports um what is tried to be done.
• 8:51
  SPEAKER_01: And I think that um, you know, that's something we have to move into the aesthetics industry and we have to build back that trust of, you know, um, you know, science, here's data, we have to believe data, and then we have to act on that data.
• 9:06
  SPEAKER_00: Well, I think it's a very, very interesting uh that you brought this up because you know, from my standpoint, I I, you know, I also have a medical background and a research background, and one of the biggest things I think um that I notice in the skincare industry, for example, is that you know, people don't it's like you can give them numbers and you can tell them that this was found in such and such a clinical trial to be effective, but then they have a hard time understanding the overall picture, right?
• 9:34
  SPEAKER_00: Like if you know what I mean.
• 9:35
  SPEAKER_00: Like that it's like they don't understand, I think, where everything is fitting in.
• 9:39
  SPEAKER_00: Like, for example, you know, you have something like hyaluronic acid, and you know, you have all this data around it, all this these publications, but for some reason the consumers are still very confused about hyaluronic acid.
• 9:52
  SPEAKER_00: You know, there's still questions like, well, what's the best molecular weight?
• 9:55
  SPEAKER_00: What's you know, how does it penetrate?
• 9:57
  SPEAKER_00: All these kind of questions, but it's like if you go to the research, it's answered already.
• 10:01
  SPEAKER_00: So there is this giant disconnect between, you know, like consumers and the biomedical industry.
• 10:07
  SPEAKER_01: Yeah, and I think, you know, unfortunately, you know, we're in a competitive world and you have different companies that are competing against each other.
• 10:15
  SPEAKER_01: And, you know, so you have this war that's out there of saying, you know, this is the information you need to have.
• 10:21
  SPEAKER_01: Um, and it, but it's only part of the information, right?
• 10:25
  SPEAKER_01: So, you know, you I I think sometimes you need independent uh parties to say, okay, so on the HA question, you look at them and compare, and you say, okay, I'm gonna, you know, get this data that's out there and I'm gonna analyze it and I'm gonna compare it.
• 10:37
  SPEAKER_01: And I, and what we're gonna say is, you know, here are the answers.
• 10:41
  SPEAKER_01: And this is why, you know, this this product is better, because you know, when we analyzed it, um, you know, this is what we've discovered.
• 10:49
  SPEAKER_01: Um, and you know, companies aren't gonna do that, you know, against themselves, right?
• 10:55
  SPEAKER_01: So somebody else has to be that independent third party that does it, or you know, um, you know, and I think that's um when you advertise, you know, you obviously you want to focus on the positive things, right?
• 11:06
  SPEAKER_01: You know, yes.
• 11:08
  SPEAKER_01: Um, and you know, so uh that that's a tough one because as long as you have companies that are supporting their own products, they're going to um, you know, promote what science they've learned or what their products does.
• 11:24
  SPEAKER_01: And um, you know, probably in most instances stay away from you know other information that's out there that might not support what their product does.
• 11:36
  SPEAKER_01: Right.
• 11:37
  SPEAKER_00: Exactly, or only like certain ingredients that are like, you know, beneficial that are in their formulation, you know, they'll they'll highlight those, but then they'll ignore like all other ones that everyone's questioning, you know.
• 11:49
  SPEAKER_01: Well, you know, and here's an interesting thing, you know.
• 11:51
  SPEAKER_01: I mean, uh, and I'm a business person, not a scientist, but you know, the the one thing that my my colleagues at NIH used to love about me, they says you're not a scientist, but you ask some darn good questions.
• 12:01
  SPEAKER_01: And so, you know, we're looking at um, you know, you're looking at products, right?
• 12:05
  SPEAKER_01: And uh I look at the the beauty magazines, and you know, it's great they have, you know, this, you know, physician or um somebody talking about, well, in the morning, you know, I put on these, you know, four products, and then at night I put on these, you know, five products.
• 12:18
  SPEAKER_01: And you know, you look at that, and I said, you know, well, they're not even the same brands, right?
• 12:23
  SPEAKER_01: You know, but one's H A, one's uh retinol, one's uh vitamin C, you know, blah, blah, blah, whatever they are.
• 12:30
  SPEAKER_01: And then, you know, I said, Well, how do they know that they don't counteract each other?
• 12:35
  SPEAKER_00: Yes, thank you so much for saying that.
• 12:37
  SPEAKER_01: Yes, yes, there's an ingredient in there that doesn't, you know, you know, obviate the good that the other product you just put on did, you know, and so um and so more isn't always better.
• 12:49
  SPEAKER_01: And that is one of the things that we're, you know, at Aesthetics by Medical, we're trying to get to is a more simple simple approach to things.
• 12:56
  SPEAKER_01: So, like our product, um, so me, um, which is so me, skincare, that's all you.
• 13:02
  SPEAKER_01: Um, now this is some new knowledge.
• 13:04
  SPEAKER_01: We um platelet rich plasma, which is well known and is, you know, out there in the market um in terms of um its benefit.
• 13:12
  SPEAKER_01: You know, there's a lot of science behind platelet rich plasma, especially in the orthopedic world, about why it benefits, you know, collagen, elastin, repair, etc.
• 13:20
  SPEAKER_01: Um, it started to be used in the aesthetics field.
• 13:23
  SPEAKER_01: Um, but the it was um it would only be stable for four to six hours, and then the platelets degranulate.
• 13:29
  SPEAKER_01: Well, we found a way of stabilizing those platelets so that they stay in their natural state for up to 120 days.
• 13:36
  SPEAKER_01: Now, when we got up this product, it's got 22 ingredients.
• 13:40
  SPEAKER_01: That's it.
• 13:41
  SPEAKER_01: They're all natural, right?
• 13:44
  SPEAKER_01: Wow.
• 13:45
  SPEAKER_01: There's nothing um in it that's not, it's you know, and no animal cruelty, all of the things that are you know trendy right now, but we didn't do it to be trendy, we did it to be simple.
• 13:55
  SPEAKER_01: Um and so, and then you know, we believe that you don't need anything else.
• 14:00
  SPEAKER_01: Wash your face, use some me, and go to bed.
• 14:07
  SPEAKER_01: You know, but but it's really hard to convince people that you don't need to put all the other products on top of it, you know.
• 14:13
  SPEAKER_01: So it's it's just something that I think um, you know, we'll continue to try to keep a simple approach.
• 14:19
  SPEAKER_01: Um, and then we'll hopefully do more studies that show this simple approach works.
• 14:24
  SPEAKER_01: Um, and that um, you know, we have enough complications in our life.
• 14:28
  SPEAKER_01: I don't need to figure out 25 skincare products that I have to put on my face daily.
• 14:31
  SPEAKER_00: Exactly.
• 14:32
  SPEAKER_00: Thank you for saying that once again.
• 14:34
  SPEAKER_00: Yes, exactly.
• 14:35
  SPEAKER_00: And you know, I know that minimalism right now is becoming another trend.
• 14:39
  SPEAKER_00: And, you know, I like to see that because it's like at the end of the day, I mean, the some of the dermatologists that I've interviewed, a lot of them will tell you, you know, all you really need is a moisturizer.
• 14:48
  SPEAKER_00: Use Vaseline, you know, and like I'm sitting here like, wait a minute, like I can't believe that Vaseline is all you need.
• 14:55
  SPEAKER_00: And you know, it's it's just such a it's so many different like opinions, and it's never like in the skincare industry and never like a decisive answer.
• 15:03
  SPEAKER_00: Like, this is what you should be going for in terms of bettering your skin health.
• 15:07
  SPEAKER_00: So I like that you said that you know, it's it's just a quick step and that's all you need because I I don't believe in the 25-step ritual either.
• 15:15
  SPEAKER_01: Well, the reason I I mean I say that, and and there are probably people that are listening to this would totally disagree and say, no, you need to do this.
• 15:22
  SPEAKER_01: But what we approached on this is when you are able to use your own platelets, platelet-rich plasma, you know, you um the the platelets have a number of biomolecules, hundreds of biomolecules that are contained in those platelets.
• 15:38
  SPEAKER_01: And when you are able to activate them on your face, the biomolecules are able to um be of a adult weight that will be absorbed into the skin.
• 15:46
  SPEAKER_01: Um, you know, and it then it's your body doing what it naturally does, right?
• 15:53
  SPEAKER_01: So we're not trying to say that, you know, so me is like the be-all end-all.
• 15:57
  SPEAKER_01: What we're saying is that you know, we've created the ability for you to use your platelets to let your body do what your body does really well.
• 16:04
  SPEAKER_01: Um, you know, if you can do that, how you know, and maybe technology can, you know, will you know find things to, you know, I mean, you do have different skin conditions like you know, rosacea or um acne and things that um you know you need to have treated with with different um topicals, and that's important.
• 16:25
  SPEAKER_01: You need to do the research behind it.
• 16:26
  SPEAKER_01: But I think for your day-to-day skincare, I think if you can keep it simple, keep it natural, you know, just like with um other treatments, you know, you know, we have the Vivaci, it's RF microneedling, you know, basically it's stimulating, you know, it's it's using radio frequency and needles to create purposeful injury so that your body kicks into gear and repairs it and that stimulates your collagen and elastic.
• 16:51
  SPEAKER_00: It's natural, you know.
• 16:52
  SPEAKER_00: Um, it is.
• 16:54
  SPEAKER_00: And you know, I think the the for me when I think about it, you know, it makes sense.
• 16:59
  SPEAKER_00: Medically, it all makes sense.
• 17:01
  SPEAKER_00: But I am just curious for everyone listening out there, you know, I think this is a good point to mention that, you know, um what Ms.
• 17:07
  SPEAKER_00: Guerrera is saying is that you know, you we really as consumers have to do our research because you know, these kind of everything you've described so far, I mean, there's no reason why anybody in the skincare industry, consumer, you know, sector, why you wouldn't gravitate towards this.
• 17:23
  SPEAKER_00: You know what I mean?
• 17:24
  SPEAKER_00: And and it's like because you can't sell products based on is it clean beauty or is it you know vegan beauty?
• 17:30
  SPEAKER_00: It can be everything, but still scientifically relevant.
• 17:32
  SPEAKER_00: And I think that's something that a lot of people are having a hard time grasping right now in this industry because there's this division, you know, there's this that either you're clean or you're scientific or medical grade, you know, uh skincare or or therapy or you're you know something else.
• 17:47
  SPEAKER_00: And I just I don't I've never understood that because I think you can definitely combine them all.
• 17:51
  SPEAKER_01: Well, and I mean I guess it's you've got to get away from the trends, you know, just because it's vegan doesn't mean it's good.
• 17:57
  SPEAKER_01: I mean, well let me say it doesn't mean it's gonna do what you want it to do, right?
• 18:02
  SPEAKER_01: It you know, so you know, you you have to say, and you know, again, animal cruelty.
• 18:07
  SPEAKER_01: I mean, I you know, I I just picked up a stray cat, and you know, I mean, I'm so like such an animal lover.
• 18:13
  SPEAKER_01: And um, but on the other side of it, you know, how do you advance research sometimes if you don't do testing with animals, right?
• 18:21
  SPEAKER_00: I actually asked another panelist this earlier, the same question you just addressed.
• 18:26
  SPEAKER_00: I said, how can we possibly make improvements and innovations in medicine if you don't let people test on something?
• 18:33
  SPEAKER_00: You know what I mean?
• 18:34
  SPEAKER_00: We can't have everything be in a petri dish.
• 18:37
  SPEAKER_00: You know what I mean?
• 18:38
  SPEAKER_00: Petri dishes don't translate into live human skin that's being, you know what I mean, like you're applying this on to and it's going through its own molecular cascade of events.
• 18:47
  SPEAKER_00: Like there's a whole, you know, it's it's a totally different world in vitro and in vivo.
• 18:51
  SPEAKER_01: Yes, it is.
• 18:52
  SPEAKER_01: I mean, and you want to do um as much as you can, you know, um, without going into animals.
• 18:58
  SPEAKER_01: But then, you know, I when I used to work at NIH, because we had uh PETA that was always out there, because if you did any research um, you know, in chimpanzees or you know, in that, you we had them lined up.
• 19:09
  SPEAKER_01: And, you know, again, it's this dilemma, you know, if you if where are you gonna test?
• 19:13
  SPEAKER_01: You're gonna test it on humans, um, you know, and what if it doesn't work?
• 19:17
  SPEAKER_01: And then, you know, you're gonna have, unfortunately, then the whole legal system's on you because you've put in a human and it didn't work.
• 19:23
  SPEAKER_01: And, you know, so it's yeah, we struggle with a lot of things when you're when you look at science and um, you know, and and what's the right thing to do.
• 19:30
  SPEAKER_01: But I think you start out, you know, you try to do as much as you can, you know, in in the test tube or in the Petri dish.
• 19:38
  SPEAKER_01: Um, you get information and there's a point in time if you need to move it on to um, you know, other studies um, you know, in animals, you do it with um, you know, in a humane way, um, you know, and then you bring it to people.
• 19:51
  SPEAKER_01: Um so that's a double benefit.
• 19:53
  SPEAKER_01: Um, so I I mean it's not an easy, it's a it's not an easy situation, but I think you can do things the right way, you know.
• 20:01
  SPEAKER_01: I mean aside, but you know, when we were, you know, at NIH, we used to um, you know, if we did studies, we had this whole thing, we had to look at the labs that we used for any of our animal studies.
• 20:15
  SPEAKER_01: And I was doing a tour of it and we were listening to it, and I found out, realized that like the in uh and this probably makes sense because it's animals, but the HVAC system was like eight times better than we had in the hospital, you know, for our patients.
• 20:29
  SPEAKER_01: Yeah, because we were trying so hard to make sure that we we had the right environment and all of that, and uh you know, and and and all our chips had to be in their own individual rooms.
• 20:40
  SPEAKER_01: And I'm looking at patients and they're stuffed in two rooms or four.
• 20:45
  SPEAKER_00: We have care for animals, yeah.
• 20:48
  SPEAKER_00: I mean, well, we have health care now for animals, you know what I mean?
• 20:52
  SPEAKER_00: So like health insurance.
• 20:54
  SPEAKER_01: I mean, I tell people I said, you know, I mean, I I wish I had a farm and I could just any stray animal or you know, whether dog, cat, you know, bird, turtle, whatever, I'd have them in my house.
• 21:04
  SPEAKER_01: But, you know, I guess everything's a balance, and you know, and and at some point in time you have to say, you know, what's the problem?
• 21:10
  SPEAKER_01: You know, so like COVID, I mean, it's killing the world.
• 21:13
  SPEAKER_01: So what do we have to do, you know, um, you know, to solve the problem.
• 21:17
  SPEAKER_01: And, you know, and I I think that's it, it's just use some intelligence and you know, um, to bring to science as well as to, you know, bring to the consumer.
• 21:26
  SPEAKER_01: Um, but if you can do it without, you know, um animal studies, if if you can do it, then that's great.
• 21:33
  SPEAKER_00: Yeah, yeah, I totally agree with that.
• 21:35
  SPEAKER_00: And I I'm so glad that you elaborated on that, on that whole topic, because I think there's definitely a lot more that needs to be learned, you know, in this area.
• 21:43
  SPEAKER_00: And I think a lot more understanding needs to go into it, you know.
• 21:46
  SPEAKER_00: Like we all want skin, we we all want discovery in in the area of skin health, but it's you know, it's more of a question of how bad do you really want it?
• 21:54
  SPEAKER_00: You know, and and how do you want it?
• 21:56
  SPEAKER_00: Do you want it to be done scientifically and follow the scientific.
• 22:00
  SPEAKER_00: Method, which I still think a lot of people don't understand.
• 22:03
  SPEAKER_00: That's really what goes on behind the scenes on the medical side, is that there's a very strict protocol in place and there's a lot of approvals.
• 22:10
  SPEAKER_00: And, you know, and I don't think that translates very, you know, very well to like the layman understanding of you know medical discovery.
• 22:19
  SPEAKER_00: So I think that's something that a lot of people, most people, including myself, I think we need to do a lot more research into that.
• 22:25
  SPEAKER_01: Well, it's it's a complicated, you know, it's complicated, and you can't expect people to do it.
• 22:29
  SPEAKER_01: I think what we have to, you know, make sure is that um there are either like the good to housekeeping, you know, seal of approval or you know, these these things where there's trusted sources and you know, these trusted sources the consumer can rely on, you know, again like NIH, it's a we are so blessed in you know to have the NIH here um, you know, and doing the research that we're doing in so many different areas.
• 22:55
  SPEAKER_01: I mean, and um, you know, it it truly is an amazing organization that supports our country and supports advancements.
• 23:03
  SPEAKER_01: Um, you know, and they do, they have a, you know, the institute of um, what's the uh I don't know if they've changed it, but one with skin, you know.
• 23:11
  SPEAKER_01: Um they're looking at dermatology and they're looking at that.
• 23:14
  SPEAKER_01: And, you know, um they may be looking at it for cancer and skin, but you know, there's information that's that they're gonna glean that can be applied to, you know, um, you know, our industry, you know, the industry, you know, and I mean, so um, so I I think we in the United States are really, really blessed um with the research and you know, the universities that do the research they do.
• 23:36
  SPEAKER_01: And um, you know, I think what we miss is how do we make that connection between trusted sources and the products that are out there on the market.
• 23:45
  SPEAKER_01: And the more we can do for that, the the better.
• 23:48
  SPEAKER_01: Um I agree.
• 23:49
  SPEAKER_01: I agree fix it all, but I at least in my little world of aesthetics biomedical, I will do my best to do that.
• 23:55
  SPEAKER_00: Well, you're definitely doing a lot more than 99% of people.
• 23:58
  SPEAKER_00: I can say that for sure, you know.
• 24:00
  SPEAKER_00: So I really hats off to you.
• 24:01
  SPEAKER_00: I love everything that you've explained and what you're doing.
• 24:04
  SPEAKER_00: I, you know, one one thing I brought up, and I don't know, um, I would love to get your opinion on this, is the idea of, you know, the skincare industry is a multi-billion dollar industry at this point.
• 24:15
  SPEAKER_00: And, you know, you have all these brands.
• 24:17
  SPEAKER_00: And I and I remember I was talking to a founder a while ago, and I brought up the idea that why don't companies contribute to this like fund, you know, that is very much structured, like how the NIH distributes, you know, grant grant money and grant funding, where the research is done in trusted laboratories and and trusted facilities that are going to give an unbiased, you know, report, which is going to be more, I think, in sync with peer-reviewed articles that get published rather than just companies coming out with data, which nobody really knows much about because you know they don't disclose any of their protocols or how they went about it or where the participants came from.
• 24:54
  SPEAKER_00: You know what I mean?
• 24:54
  SPEAKER_00: So like I've always wondered that, like, why there can't be this more collaborative effort where we have a fund and we have the money to do real research that can then be published and then also benefit brands.
• 25:06
  SPEAKER_00: So I would love to see hear your opinion on that.
• 25:08
  SPEAKER_01: Yeah, I I think that's uh an interesting question.
• 25:11
  SPEAKER_01: So um when I look at like how we spend our research money, um, you know, it we have very specific questions, like, you know, um if we're looking at um our product compared to nothing or our product in combination with something, and so it gets very specific.
• 25:32
  SPEAKER_01: And um, you know, if you had a a central organization, you know, like other than an NIH, you um the questions that are asked are very specific to your product.
• 25:44
  SPEAKER_01: And so it would, I think it would be very difficult to manage that, you know, because you'd have all of these commercial enterprises that would be want to be asking specific questions about their product.
• 25:54
  SPEAKER_01: Um and and sometimes um, you know, I used to again say at NIH that we should have the the um publication of failed research, right?
• 26:04
  SPEAKER_01: I mean, you publish everything that works, but you don't publish what didn't work, right?
• 26:09
  SPEAKER_00: Doesn't work, yes.
• 26:10
  SPEAKER_01: Oh my gosh, yes.
• 26:11
  SPEAKER_01: So many times you you learn from what doesn't work, right?
• 26:16
  SPEAKER_01: Um you know how if you're in the business world, you know, you if you've just spent a lot of money learning what doesn't work, um, you know, sometimes you want to keep that to yourself.
• 26:25
  SPEAKER_01: So if somebody else has to spend that money, that's you know, because it's competitive.
• 26:30
  SPEAKER_01: I mean, unfortunately, you know, you you know, businesses, you know, you've got investors and they want to make money and they want to do this.
• 26:37
  SPEAKER_01: And so, you know, well, I, you know, would love to have an organization you could go to that would do these studies.
• 26:43
  SPEAKER_01: I think it would be really hard to have that happen.
• 26:47
  SPEAKER_01: Um, and I think the closest you you can get to a lot of that is by having, you know, institutions like NIH that actually do a lot of research that are, you know, basic, you know, uh the biology and you know, of mechanisms of action, why things work.
• 27:03
  SPEAKER_01: And you know, that you look at, you know, what are those mechanisms of action, you know, and how do you apply it to your particular industry or your disease problem or your um, you know, the therapy that you're trying to create.
• 27:16
  SPEAKER_01: Um, but I like where you're going, but I think it would be really hard to do it just because of the competitive nature of industry, and you know information is is really important and you want to keep it um good stuff and bad stuff sometimes.
• 27:30
  SPEAKER_01: Um, you know, sometimes the best way to protect intellectual property is like you know, Coca-Cola.
• 27:36
  SPEAKER_01: You just never patent it, you just keep coca, you know, and so um I think industry always faces that, you know, is you know, we have to think about great science and we have to think about great products, but we you also have to think about business because somebody won't invest in you if you're not you know showing you know good bottom lines.
• 27:55
  SPEAKER_01: It's tough.
• 27:55
  SPEAKER_01: I mean, I've uh this has been a whole new world um when I founded this company and have been tried to you know juggle all of these things and regulatory and all of the stuff.
• 28:05
  SPEAKER_00: I bet.
• 28:05
  SPEAKER_00: I bet it's uh it's it's an immense task.
• 28:08
  SPEAKER_00: Yeah, I I can imagine.
• 28:09
  SPEAKER_00: And you know, I really hats off to you because you're you know you're doing a wonderful job and you've taken on something very big.
• 28:15
  SPEAKER_00: So, you know, I have um much admiration for your work.
• 28:19
  SPEAKER_01: So this is why I said the aesthetic industry, you know, you you start a new business and you age 10 years to one.
• 28:24
  SPEAKER_01: So we need to have product.
• 28:29
  SPEAKER_00: We need you're absolutely right.
• 28:31
  SPEAKER_00: We need a skincare line dedicated to all of the business professionals out there that are aging because of all the one you age 10 years and one like a dog, seven years to one.
• 28:43
  SPEAKER_00: Oh, I love that.
• 28:44
  SPEAKER_00: I love that analogy.
• 28:46
  SPEAKER_00: Well, thank you so much, Marianne.
• 28:47
  SPEAKER_00: This has been such a pleasure speaking with you, and I would love to have you back anytime if you have the the room in your schedule to just cover one topic if you want and just dive deeper.
• 28:57
  SPEAKER_01: Oh, I I I would love to do that.
• 28:58
  SPEAKER_01: This has been a joy too, because it's uh you've touched on so many things that are obviously near and dear to my heart.
• 29:03
  SPEAKER_01: Um and I don't need to live and breathe it every day anymore.
• 29:06
  SPEAKER_00: So thank you very much.
• 29:08
  SPEAKER_00: It's my pleasure.
• 29:09
  SPEAKER_00: Um so that's the end of the recording, but I wanted to ask you because I'm I'm just promoting myself.
• 29:14
  SPEAKER_00: I actually am applying next year for match in plastic surgery and dermatology, and I am trying to make as many connections as I can.
• 29:21
  SPEAKER_00: Um, I've actually done a lot of research.
• 29:23
  SPEAKER_00: So um I would love it if you have any advice for me or any contacts I can connect with, um, you know, at all.
• 29:32
  SPEAKER_00: Yeah, I mean, in terms of um where you would do um a residency or where you would do Yeah, I'm applying for a residency, but I also like I'm really interested in uh, you know, research in dermatology and and skin health.
• 29:43
  SPEAKER_00: And I, you know, I I have done a lot of research in the in the past, but I would love to, you know, even a research opportunity or a mentor of some kind.
• 29:51
  SPEAKER_01: Well, you know, I mean we'd be happy to um I'd have be really happy to have you talk to our uh chief science officer.
• 29:57
  SPEAKER_01: He's also uh helped do a couple startup companies and has been through this whole thing and he's um spent time at um J and J and then um yeah, I mean so is it not J and J, it's um oh Proctron Gamble, P G um in Cincinnati.
• 30:13
  SPEAKER_01: So he came out of Oh, I'm from Cincinnati.
• 30:15
  SPEAKER_00: I am from Cincinnati, actually.
• 30:17
  SPEAKER_01: Yeah, I'm a buckeye too.
• 30:19
  SPEAKER_01: I'm uh I'm from um I actually graduated from Ohio State, so I'm a huge buckeye.
• 30:23
  SPEAKER_01: I grew up in northeastern Ohio.
• 30:25
  SPEAKER_00: Um such a small world.
• 30:28
  SPEAKER_00: Yeah, I went to the University of Cincinnati for my bachelor's and my MBA, and I am I'm a bear cat all the way, but I love Ohio.
• 30:35
  SPEAKER_01: Larry, I think Larry graduated from the University of Cincinnati because that's where he was um from, I believe.
• 30:41
  SPEAKER_01: So but Larry is his name, and I'd love to hook you up with him.
• 30:45
  SPEAKER_01: And you know, maybe you can even work with us on some of the things that oh my god, yes, please, yes, please.
• 30:51
  SPEAKER_00: I am down.
• 30:52
  SPEAKER_00: Anything you can uh hop, anything I can hop into, I'm down.
• 30:55
  SPEAKER_00: Seriously, I love science, it is my passion, and any any opportunity I welcome.
• 31:00
  SPEAKER_00: So, yes, please.
• 31:01
  SPEAKER_01: Well, um, do you you've got my contact, or Sheldon can give you, or Kaylee, whoever you're talking to, to give you my contact.
• 31:07
  SPEAKER_01: And let's hook up by email and then I'll I'll get you set up with Larry to talk to, and and we'll do whatever we can to make any connections.
• 31:14
  SPEAKER_01: Thank you so much, Marianne.
• 31:16
  SPEAKER_01: You're amazing.
• 31:17
  SPEAKER_01: Thank you so much.
• 31:18
  SPEAKER_01: Well, my pleasure.
• 31:18
  SPEAKER_01: You know, I I have to say, um, when the our company, when we got started, it you know, you're small, you don't have much money.
• 31:26
  SPEAKER_01: And um, we had um I believe in the universe, we had Chino Beyon, and we're talking about the universe and positive energy and all of that.
• 31:34
  SPEAKER_01: And uh we had this young intern walk in, right?
• 31:37
  SPEAKER_01: He's out of the ASU and um he um came into my office and we started talking.
• 31:43
  SPEAKER_01: So, you know, I said, Oh, sure, well, I'll give you an internship.
• 31:45
  SPEAKER_01: You know, we'll just try this.
• 31:47
  SPEAKER_01: And you know, ended up, he's our director of RD now.
• 31:50
  SPEAKER_01: He's the one who came up with the invention for and he's like 25 years old now, right?
• 31:56
  SPEAKER_01: I mean, oh my gosh, that's amazing! And Sheldon, our marketing officer, is very young too.
• 32:03
  SPEAKER_01: And he came to me and just dropped in my lap.
• 32:05
  SPEAKER_01: And I was like, oh my god, this guy's brilliant.
• 32:07
  SPEAKER_01: Um, and so we have, you know, I really love to see, you know, people that are young and energetic and have potential, maybe not experience, but have potential, and it hasn't done me wrong.
• 32:17
  SPEAKER_01: So we've got an amazing young group of incredible that sounds amazing.
• 32:22
  SPEAKER_00: I would love it if you could take your, you know, put some trust in me.
• 32:25
  SPEAKER_00: I would love to work with you seriously.
• 32:27
  SPEAKER_00: I it's it would be so amazing.
• 32:29
  SPEAKER_01: Well, where are you located now?
• 32:31
  SPEAKER_01: I'm in New York.
• 32:32
  SPEAKER_00: So I'm yep.
• 32:34
  SPEAKER_01: Well, I will definitely um hook you up.
• 32:37
  SPEAKER_01: So I'll talk to Sheldon about it.
• 32:39
  SPEAKER_01: We'll get hooked up after this and you know, we'll be in touch because I would love to do it.
• 32:43
  SPEAKER_01: I love to see energetic young folks uh getting ahead and doing what they're passionate about.
• 32:48
  SPEAKER_01: Thank you so much.
• 32:49
  SPEAKER_01: Can I have your personal email actually just to have it?
• 32:51
  SPEAKER_01: Sorry.
• 32:52
  SPEAKER_01: You know, I I use um the work one all the time because I'm you know, so just it's Marianne at aesthetics biomed.
• 33:01
  SPEAKER_01: Okay, okay, got it.
• 33:03
  SPEAKER_01: Yeah, dot com because I end up forgetting to look at the other ones.
• 33:07
  SPEAKER_01: I know I should be better than that and do that.
• 33:11
  SPEAKER_00: No worries, though.
• 33:12
  SPEAKER_00: I got it down and I'm gonna definitely take up on it.
• 33:14
  SPEAKER_01: Yeah, simplicity in life, you know, is kind of like you strive for it wherever you can get it.
• 33:19
  SPEAKER_01: True minimalism.
• 33:21
  unknown: Yes.
• 33:21
  unknown: There you go.
• 33:23
  SPEAKER_00: Well, thank you so much, Marianne.
• 33:25
  SPEAKER_00: You're amazing, and I am so, so blessed and honored to have met you and to talk to you.
• 33:29
  SPEAKER_00: Thank you so much.
• 33:30
  SPEAKER_00: Okay, you take care.
• 33:31
  SPEAKER_00: Have a good rest of your day.
• 33:35
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• 33:37
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• 33:42
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