OpenAI’s Unreleased Model Solved Math: Is Biology Next?

In the Loop AI · Oct 12, 2026 · 18m · transcript

An internal model from OpenAI reportedly solved around 90 of the hardest open mathematics problems and what that could mean for fields like physics, chemistry, and biology.

We cover expert reactions, verification challenges, and the potential for AI to accelerate work in science and pharmaceuticals.

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Timestamps

0:00 OpenAI’s Math Breakthrough

1:53 From Impossible to 90 Problems

4:39 Why This Changes Everything

8:06 Mathematicians Feel the Shock

10:30 Reasoning Spills Into Other Fields

11:37 The Cryptography Alarm

14:19 Humans Become the Bottleneck

15:56 Biology Is Next

17:26 Beyond Math…