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285-Convergence in Human Neuroscience

This perspective discusses the current state and future directions of human neuroscience, emphasizing the convergence of large-scale neurophysiology and single-cell profiling techniques. The authors highlight new tools like Neuropixels probes for high-resolution, large-scale neural activity recording in awake patients and the advancements in single-cell omics for creating comprehensive brain-cell atlases. A key focus is the development of a workflow that integrates in vivo functional mapping of human brain tissue resected during surgery with subsequent ex vivo multi-modal cellular and…

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