Latest / Resiliency Radio with Dr. Jill Carnahan, MD / 322: Resiliency Radio with Dr. Jill: The Future of Healing the Heart w/ Cardiologist Dr. Abid Husain

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322: Resiliency Radio with Dr. Jill: The Future of Healing the Heart w/ Cardiologist Dr. Abid Husain · Resiliency Radio with Dr. Jill Carnahan, MD

• 0:00
  Dr. Jill Carnahan, MD: Welcome to Resiliency Radio, your go to podcast for the most cutting edge insights integrative and functional medicine.
• 0:07
  Dr. Jill Carnahan, MD: I'm your host, Dr. Jill, and with each episode we dive into the heart of healing and personal transformation.
• 0:14
  Dr. Jill Carnahan, MD: Join me as I interview medical leaders, thought leaders, innovators and experts of all types.
• 0:20
  Dr. Jill Carnahan, MD: Today you're in for a real treat.
• 0:22
  Dr. Jill Carnahan, MD: This is a colleague and friend of mine who is a cardiologist now personally practicing regenerative and longevity medicine in Boulder, Colorado.
• 0:29
  Dr. Jill Carnahan, MD: He's a neighbor, he's a friend.
• 0:30
  Dr. Jill Carnahan, MD: I've seen him grow through the process into an expert in longevity and functional medicine.
• 0:35
  Dr. Jill Carnahan, MD: And we're also going to dive into the heart.
• 0:36
  Dr. Jill Carnahan, MD: So if you have any concerns or someone you know with heart issues, you're going to get a very integrative, holistic perspective on heart health.
• 0:43
  Dr. Jill Carnahan, MD: So stay tuned.
• 0:43
  Dr. Jill Carnahan, MD: I'll introduce him in just a second.
• 0:46
  Dr. Jill Carnahan, MD: One thing I always want to remind you is that we are taking on new patients at Flatiron Functional Medicine, my Clinic in Lewisville, Colorado.
• 0:54
  Dr. Jill Carnahan, MD: You can call 303-993-79 to schedule or visit us at www.jillcarnahan.com to find out more about our providers and practitioners.
• 1:06
  Dr. Jill Carnahan, MD: If you have any questions, just give us a call.
• 1:08
  Dr. Jill Carnahan, MD: You can also email info flatiron functional medicine.com and as always, you know we have incredible products and services@drj health.com Things like Bergamot, which we're going to discuss today, so stay tuned.
• 1:21
  Dr. Jill Carnahan, MD: Or our Dr. Joe Beatty line.
• 1:23
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• 1:27
  Dr. Jill Carnahan, MD: For those of you wanting a healthy glowing skin on your neckline, this is great for you.
• 1:33
  Dr. Jill Carnahan, MD: You can find that@drjill health.com as well.
• 1:36
  Dr. Jill Carnahan, MD: Okay, now I want to introduce our guest.
• 1:38
  Dr. Jill Carnahan, MD: Dr. Hussain is among the revolutionary few who are changing the way cardiovascular disease is addressed.
• 1:44
  Dr. Jill Carnahan, MD: After years of working in conventional cardiology, he realized the limitations of the system and began seeking ways to improve highly impactful preventative care.
• 1:53
  Dr. Jill Carnahan, MD: This leads to.
• 1:53
  Dr. Jill Carnahan, MD: This led to years of advanced and functional medicine, bioidentical hormone replacement therapy, peptide therapy and regenerative medicine.
• 2:01
  Dr. Jill Carnahan, MD: Today, Dr. Dr. Abid combines all that he has learned and applying individual therapies from all fields of medicine to provide unique and comprehensive cardiovascular care.
• 2:11
  Dr. Jill Carnahan, MD: In addition to clinical practice, he seeks to improve cardiac care on a larger scale through education and scientific advisory roles.
• 2:18
  Dr. Jill Carnahan, MD: And you'll be.
• 2:19
  Dr. Jill Carnahan, MD: Stay tuned.
• 2:19
  Dr. Jill Carnahan, MD: With today's episode.
• 2:20
  Dr. Jill Carnahan, MD: You'll hear about a new course he has.
• 2:22
  Dr. Jill Carnahan, MD: So let's welcome Dr. Dr. Hussain.
• 2:26
  Dr. Jill Carnahan, MD: Dr. Hussain, we've been friends and pals for a while in this space and we're neighbors.
• 2:30
  Dr. Jill Carnahan, MD: And I'm so excited to have you on Resiliency radio to talk about all things longevity, performance and also your background in cardiology.
• 2:39
  Dr. Jill Carnahan, MD: Why don't we start just a little bit about your background.
• 2:41
  Dr. Jill Carnahan, MD: How did you get into medicine and then how did you get to where you're at now with longevity, performance and the background in cardiology?
• 2:49
  Dr. Abid Husain: Sure, sure, yeah.
• 2:50
  Dr. Abid Husain: Love to tell you about this.
• 2:52
  Dr. Abid Husain: So.
• 2:53
  Dr. Abid Husain: So my interest in medicine actually started in, it was in college when I was at a particular point in my life when I had to decide whether I wanted to.
• 3:02
  Dr. Abid Husain: I had a fascination with the human body.
• 3:05
  Dr. Abid Husain: That's what it started with.
• 3:06
  Dr. Abid Husain: And at that time I wanted to go into the arts.
• 3:10
  Dr. Abid Husain: I wanted to study the human body as an art form.
• 3:13
  Dr. Abid Husain: And then I took gross anatomy.
• 3:15
  Dr. Abid Husain: And coming from a family of physicians, as well as having a very science oriented brain, that just sparked a whole amount of interest that led me down, you know, a path down to medical school, residency and fellowship.
• 3:29
  Dr. Abid Husain: And so, you know, and what led me to the, to study the heart was I really enjoyed studying the things that made everybody else scared.
• 3:39
  Dr. Abid Husain: And so, you know, finding calm in sort of the storm and sort of the peace is where I felt really good.
• 3:47
  Dr. Abid Husain: So that was my four, you know, foray into starting cardiolo, you know, and then as a lot of happens to a lot of us, we go into medicine with this specific idea of what it's going to be and it doesn't turn out to be that way.
• 4:04
  Dr. Abid Husain: You know, I worked inpatient, outpatient care for probably 10 years and it ended up being longer, but as a solo practitioner.
• 4:13
  Dr. Abid Husain: And that really led to burnout and it led to, you know, long nights, very little time off.
• 4:20
  Dr. Abid Husain: And, and I just saw the writing on the wall when I looked at some of my old colleagues who were just a shadow of themselves, they were unhealthy and they just lived in the hospital all the time and taking care of a revolving door of patients.
• 4:34
  Dr. Abid Husain: And so when I was younger, my fascination also was fitness, was a diet.
• 4:40
  Dr. Abid Husain: And they never taught us that.
• 4:42
  Dr. Jill Carnahan, MD: Right.
• 4:43
  Dr. Abid Husain: And so, you know, I thought, all right, there's got to be something in that can stop this train, this flood of people at the other end that we're taking care of that I really felt like was not making a big dent.
• 4:57
  Dr. Abid Husain: So it was the right time for me to take a step back.
• 5:00
  Dr. Abid Husain: I took a sabbatical and I also decided, okay, this is a time for me to go do something different that I really wanted to do, that I didn't do for the earlier part of my life was study the arts.
• 5:13
  Dr. Abid Husain: So I went and studied with a classic painter for a few years.
• 5:16
  Dr. Jill Carnahan, MD: Wow.
• 5:17
  Dr. Abid Husain: And I trained with him for a while in Santa Fe, a fantastic painter named Tony Ryder, you know, who's got a lineage that goes back to the classic painters, Michelangelo.
• 5:28
  Dr. Abid Husain: And it was an amazing experience.
• 5:30
  Dr. Abid Husain: And I also knew that I had to maintain my credentials and stay relevant in the field.
• 5:36
  Dr. Abid Husain: And so I kept working per diem, but my curiosity for those things like diet, exercise, root causes was still there.
• 5:45
  Dr. Abid Husain: And so at the same time, I said, let's start looking at these processes and seeing what is, what are they doing and how can I use those?
• 5:54
  Dr. Abid Husain: And so that started functional medicine training.
• 5:58
  Dr. Abid Husain: It started getting more interested in hormones, with fitness, with optimization peptides.
• 6:04
  Dr. Abid Husain: And then, you know, and then I think I was still practicing in and out of both of those fields.
• 6:10
  Dr. Abid Husain: And around 2020, I just made the.
• 6:13
  Dr. Abid Husain: The shift and completely started doing this type of medicine.
• 6:17
  Dr. Jill Carnahan, MD: What a great story.
• 6:17
  Dr. Jill Carnahan, MD: There's so many highlights.
• 6:18
  Dr. Jill Carnahan, MD: First of all, the brutality of our medical training.
• 6:21
  Dr. Jill Carnahan, MD: And even more so, orthopods and neurosurgeons and cardiologists.
• 6:27
  Dr. Jill Carnahan, MD: Those fields in particular can be so demoralizing in a way.
• 6:31
  Dr. Jill Carnahan, MD: And the truth is, even though you had this fascination with the design of the body and all of that and the root cause and being an athlete yourself, at least in my experience, many cardiologists end up being more technicians, really qualified technicians.
• 6:45
  Dr. Jill Carnahan, MD: So you're fixing a problem, but you're not trained in.
• 6:49
  Dr. Jill Carnahan, MD: And again, me neither, because I'm an MD just like you in those root cause, like, what really could we have done to prevent this process?
• 6:56
  Dr. Jill Carnahan, MD: But any one of us who go into the healing profession and arts, I think always have this, like, well, could we be doing more?
• 7:02
  Dr. Jill Carnahan, MD: And unfortunately, our medical system is wonderful.
• 7:04
  Dr. Jill Carnahan, MD: If you have a heart attack or a stroke or anything, it's not so great at going to the root cause and saying, how did you get here?
• 7:10
  Dr. Jill Carnahan, MD: And how can we reverse trajectory?
• 7:12
  Dr. Jill Carnahan, MD: And I remember meeting you, I think it was when you were doing some of the art, because I think it was probably, I don't know exactly what year that was or maybe shortly after, because I've known you for a while and it's so awesome to see that trajectory and to where you're at now, because I really think it's so powerful.
• 7:26
  Dr. Jill Carnahan, MD: One of the reasons I want to have you on is that background as a practicing cardiologist but then bringing that into this field of, like, how do we take all that knowledge and then make it.
• 7:35
  Dr. Jill Carnahan, MD: I feel like our toolbox is bigger now, right?
• 7:37
  Dr. Abid Husain: It is.
• 7:37
  Dr. Abid Husain: It grows every year.
• 7:38
  Dr. Abid Husain: And that's.
• 7:39
  Dr. Abid Husain: That's part of it.
• 7:40
  Dr. Abid Husain: We got to stay curious.
• 7:41
  Dr. Abid Husain: We have to stay also.
• 7:42
  Dr. Abid Husain: We have to be open to new ideas and stay humble.
• 7:45
  Dr. Abid Husain: And so, you know, all those things just allow.
• 7:47
  Dr. Abid Husain: Allow us to have a bigger toolbox and learn more.
• 7:50
  Dr. Abid Husain: I mean, I learn from you constantly.
• 7:52
  Dr. Abid Husain: So, yeah, it's fantastic.
• 7:54
  Dr. Jill Carnahan, MD: It's so fun.
• 7:54
  Dr. Jill Carnahan, MD: I learned from everybody as well.
• 7:56
  Dr. Jill Carnahan, MD: It's just.
• 7:56
  Dr. Jill Carnahan, MD: It's just really.
• 7:57
  Dr. Jill Carnahan, MD: And you know what?
• 7:58
  Dr. Jill Carnahan, MD: You hit on something else is that curiosity, I think, marks a true clinician, because if we forget to be curious or think that we learned it all in medical school and stop learning, that's when it doesn't go so well for anyone.
• 8:09
  Dr. Jill Carnahan, MD: Right.
• 8:09
  Dr. Jill Carnahan, MD: So how awesome that you did that and they explored, and now you're in the space with lung longevity.
• 8:14
  Dr. Jill Carnahan, MD: So what were some of the patterns and things that.
• 8:18
  Dr. Jill Carnahan, MD: Now, looking back with your reflective lens of the cardiologist and now this functionalist and expert longevity, performance, all the other things that you're doing?
• 8:27
  Dr. Jill Carnahan, MD: What.
• 8:27
  Dr. Jill Carnahan, MD: Let's first make a small critique of the conventional system, and then we'll go on to what else is available.
• 8:32
  Dr. Jill Carnahan, MD: And again, there's lots of pros.
• 8:34
  Dr. Jill Carnahan, MD: I am an MD at heart.
• 8:35
  Dr. Jill Carnahan, MD: So are you.
• 8:36
  Dr. Jill Carnahan, MD: So I'm not saying it's all bad.
• 8:37
  Dr. Jill Carnahan, MD: We're not throwing it all out.
• 8:38
  Dr. Jill Carnahan, MD: But people out there are running into this and they're going to the er and I mean, I can't tell you how many times I've had a patient come to the er and it's like, they didn't examine you, really.
• 8:48
  Dr. Jill Carnahan, MD: Like, I'll hear something like that.
• 8:49
  Dr. Jill Carnahan, MD: And I'm just shocked at the lack of curiosity, the lack of investigation, the lack of just basic clinical skills that is happening out there.
• 8:58
  Dr. Jill Carnahan, MD: And then diagnoses and stuff.
• 9:00
  Dr. Jill Carnahan, MD: Did you see any of that as a cardiologist?
• 9:03
  Dr. Jill Carnahan, MD: I'm not talking about your practice.
• 9:04
  Dr. Jill Carnahan, MD: I'm just seeing the patients that came in.
• 9:05
  Dr. Jill Carnahan, MD: Did you see a pattern of people maybe being given a stent but not talked about diet at all, or what kinds of things did you see that tipped you into this field?
• 9:13
  Dr. Abid Husain: Sure, sure.
• 9:14
  Dr. Abid Husain: That was very common.
• 9:15
  Dr. Abid Husain: You know, we.
• 9:16
  Dr. Abid Husain: We would see people that were younger and younger having heart attacks or older folks with heart failure that survived heart attacks.
• 9:24
  Dr. Abid Husain: And that was the revolving door.
• 9:26
  Dr. Abid Husain: And the.
• 9:27
  Dr. Abid Husain: The system was great at getting the specialist to where they needed to be and doing the thing Very quickly.
• 9:34
  Dr. Abid Husain: But it's also a, it's a volume based system.
• 9:37
  Dr. Abid Husain: It's not a, it's a quantity based system, not quality.
• 9:41
  Dr. Abid Husain: And so because of that, the physicians don't spend a lot of time with the patients, whether it's at an outpatient setting because they have a specific allotted amount of time that they can get, or in the hospital because there's a list of other, of a long list of other people that need to get seen.
• 9:57
  Dr. Abid Husain: They'll do what needs to get done.
• 9:59
  Dr. Abid Husain: But then there's no time to have this conversation about diet, exercise, hormones, what else can you be doing on your own to empower the patient?
• 10:10
  Dr. Abid Husain: And that takes time.
• 10:12
  Dr. Abid Husain: Time is the commodity.
• 10:13
  Dr. Abid Husain: And in a system where, in our system we allow that, we put that into our visits and make sure that we have a dialogue with them about that.
• 10:24
  Dr. Abid Husain: The modern system or the conventional system doesn't really doesn't account for that because it's driven by larger interests.
• 10:31
  Dr. Abid Husain: And those interests are not about overall foundational health.
• 10:36
  Dr. Abid Husain: It's about getting the emergency done, fixed, and then get them out the door.
• 10:42
  Dr. Jill Carnahan, MD: Yeah, gosh, again, I see it every day.
• 10:44
  Dr. Jill Carnahan, MD: But one of the best things about our practices now is I get to spend 60, 90 minutes and really know.
• 10:50
  Dr. Jill Carnahan, MD: And I bet you're experiencing this too.
• 10:52
  Dr. Jill Carnahan, MD: For me, some of the most powerful and interesting things that happen in my clinic are getting that relationship right, which we kind of weren't able to get in the old system as well.
• 11:02
  Dr. Jill Carnahan, MD: I mean, you still have relationships, but now there's this whole depth of really getting to know that person.
• 11:07
  Dr. Jill Carnahan, MD: Where do you start when you're seeing a new patient?
• 11:10
  Dr. Jill Carnahan, MD: As far as investigating the background, maybe toxic exposures, like I'm sure the lens a little broader because before it was, you know, how do we fix the artery?
• 11:20
  Dr. Jill Carnahan, MD: So go a little deeper as far as what things are you looking at now when you're seeing a new patient?
• 11:25
  Dr. Abid Husain: Yeah, I will always start with sleep.
• 11:29
  Dr. Abid Husain: Sleep is one of the critical recovery tools that we have.
• 11:33
  Dr. Abid Husain: It's foundational.
• 11:34
  Dr. Abid Husain: I have to assess where, what their sleep is like and not just from a microscopic standpoint to kind of see what their optimal sleep patterns are if they're rested.
• 11:44
  Dr. Abid Husain: But sleep apnea is a major issue that flies under the radar.
• 11:50
  Dr. Abid Husain: You don't have to be obese or overweight to have sleep apnea.
• 11:53
  Dr. Abid Husain: Plenty of people have sleep apnea that are normal weight or even thin.
• 11:57
  Dr. Abid Husain: And it just doesn't get noticed.
• 11:59
  Dr. Abid Husain: And so this is critical for brain health, for cardiac health, for hypertension, for afib so many different ways.
• 12:06
  Dr. Abid Husain: So assess the sleep and then I always assess stimulants, how many, you know, the amount of stimulants they're getting, whether it's caffeine, whether it's power drinks or supplements that have stimulant capacities to them.
• 12:20
  Dr. Abid Husain: I always assess gut health.
• 12:22
  Dr. Abid Husain: So I'm probably one, you know, there, aside from, I'm the only cardiologist that I know, aside from other functional cardiologists that really dive deep into gut tests, testing, you know, and I will make that part of my mandatory, you know, lab assessment.
• 12:40
  Dr. Abid Husain: Once I get the patient into the system and we do the initial testing, I will get a gut test to assess if there's specifically, if there's any symptoms, for sure.
• 12:49
  Dr. Abid Husain: But if there's no symptoms even then I will do a stool test because they don't have to have symptoms for something to be wrong.
• 12:56
  Dr. Abid Husain: I mean, that's what that's my case.
• 12:58
  Dr. Abid Husain: You know, I started doing all these tests and I never had any real gut problems.
• 13:02
  Dr. Abid Husain: And you know, I did a blood test, my TMAO was high and I said, oh boy, this is interesting.
• 13:08
  Dr. Abid Husain: Look at, I got to the stool test and it was all out of whack and I didn't even notice it.
• 13:13
  Dr. Abid Husain: So, so this is, you know, something that, that does beg being looked at.
• 13:18
  Dr. Abid Husain: The other thing that I do at some point is do I do a toxic burden?
• 13:21
  Dr. Abid Husain: Yeah, because a toxic burden is vital as well.
• 13:24
  Dr. Abid Husain: You know, we live in an incredible soup of toxic exposures and metals, you know, particulate air forever, chemicals, all of those things.
• 13:36
  Dr. Abid Husain: Important to assess those.
• 13:38
  Dr. Abid Husain: And then what I also make sure to ask about COVID because, you know, Covid exposure is, you know, there is, there are long term effects, it does trigger autoimmune problems and it is a very specific vascular toxic agent, you know, or toxic damaging process.
• 13:59
  Dr. Abid Husain: So it's important to know what their Covid exposure has been because it can accelerate atherosclerosis.
• 14:05
  Dr. Jill Carnahan, MD: Wow, that's a great overview.
• 14:07
  Dr. Jill Carnahan, MD: And I love that you're combining that, you know, cardiology background.
• 14:10
  Dr. Jill Carnahan, MD: Now I'm assuming now it's not just heart patients, it's any general someone who wants w performance.
• 14:15
  Dr. Jill Carnahan, MD: And your scope is much broader, which is so cool.
• 14:18
  Dr. Jill Carnahan, MD: Like I said, for your background.
• 14:19
  Dr. Jill Carnahan, MD: Interesting.
• 14:19
  Dr. Jill Carnahan, MD: I love that you mentioned some of the gut things, especially for a cardiologist because I have one really interesting case of a, you know, 40 something year old dentist that had congestive heart failure of no known cause.
• 14:32
  Dr. Jill Carnahan, MD: We ended up Finding it was a viral cardiomyopathy.
• 14:36
  Dr. Jill Carnahan, MD: And she also had very elevated tmao, and it's totally normal now.
• 14:40
  Dr. Jill Carnahan, MD: But it was that gut microbiome that was creating the, you know, conversion of carnitine and all of that into the tmao.
• 14:47
  Dr. Jill Carnahan, MD: And for me, it was a fascinating thing to realize.
• 14:50
  Dr. Jill Carnahan, MD: This is so connected to the gut, you know, just.
• 14:53
  Dr. Jill Carnahan, MD: And again, that's so great that you check that.
• 14:54
  Dr. Jill Carnahan, MD: I'm assuming you probably check TMAO on every patient and searching.
• 14:58
  Dr. Abid Husain: Yeah, I checked that.
• 14:58
  Dr. Abid Husain: And I particularly look for, like, specific things.
• 15:02
  Dr. Abid Husain: We use the.
• 15:02
  Dr. Abid Husain: Depending on the time the test that's optimal.
• 15:05
  Dr. Abid Husain: We try and look for things that are part of leaky gut and lipopolysaccharide exposure because that in particular is more targeted towards vascular damage.
• 15:15
  Dr. Jill Carnahan, MD: Yeah, that makes sense.
• 15:16
  Dr. Jill Carnahan, MD: Yeah.
• 15:16
  Dr. Jill Carnahan, MD: LPS is under everything, isn't it?
• 15:19
  Dr. Jill Carnahan, MD: Very cool.
• 15:20
  Dr. Jill Carnahan, MD: And then talk about from a cardio perspective.
• 15:23
  Dr. Jill Carnahan, MD: Obviously we have the technician part that you did before, and now you have someone come in with coronary artery disease or signs of, you know, an abnormal stress test.
• 15:32
  Dr. Jill Carnahan, MD: Obviously you're doing the toxin and all that stuff.
• 15:34
  Dr. Jill Carnahan, MD: But what are some common interventions that you might do that you didn't do before?
• 15:39
  Dr. Abid Husain: Yeah, well, part of the assessment also is gonna.
• 15:44
  Dr. Abid Husain: I try and do a CT coronary angiogram that's going to give me, you know, some clear phenotypic or anatomic data to see what may be showing up in their lab tests that are translating to their anatomy.
• 15:59
  Dr. Abid Husain: And then that'll.
• 16:00
  Dr. Abid Husain: That will dictate, you know, a lot of the, Some of the interventions.
• 16:03
  Dr. Abid Husain: I look at the.
• 16:04
  Dr. Jill Carnahan, MD: Both.
• 16:04
  Dr. Abid Husain: Both of them.
• 16:05
  Dr. Abid Husain: The first thing is I want to look at the particle sizes.
• 16:09
  Dr. Abid Husain: And this is, I think one of my, one of the, my soapboxes over the past year has been that the conventional community just looks at cholesterol, and if we're lucky, they look at.
• 16:23
  Dr. Abid Husain: Maybe they'll.
• 16:24
  Dr. Abid Husain: They'll break it down to LDL and hdl.
• 16:26
  Dr. Abid Husain: Now that's still really, you know, a sad and really poor assessment of cardiovascular health.
• 16:34
  Dr. Abid Husain: There's so many instances where an LDL just misses or overestimates risk.
• 16:39
  Dr. Abid Husain: And so we end up getting, you know, completely mistargeting who we should be targeting, who should be getting optimum lipid therapy.
• 16:47
  Dr. Abid Husain: So, you know, the lipid therapy, it can vary.
• 16:51
  Dr. Abid Husain: You know, we can.
• 16:52
  Dr. Abid Husain: It depends on the.
• 16:54
  Dr. Abid Husain: Where the patient's coming from.
• 16:56
  Dr. Abid Husain: I'm not against using pharmacologic agents if I'm going to use.
• 17:00
  Dr. Abid Husain: If a person meets the criteria to use a statin or a PCSK9 or bempedoic acid, then we'll.
• 17:06
  Dr. Abid Husain: We'll start those medications.
• 17:08
  Dr. Abid Husain: But it's after a long discussion with the patient talking about the risks, do they meet a criteria for potentially having some of those risks?
• 17:19
  Dr. Abid Husain: And if we even have some genetic tests that we can see if they're at, you know, if they build up the medication, if they don't metabolize it, well, that really helps.
• 17:27
  Dr. Abid Husain: So, you know, there's a discussion about that.
• 17:29
  Dr. Abid Husain: If they don't want to use that, there's still plenty of agents that I use that are.
• 17:33
  Dr. Abid Husain: That are herbal or supplemental that'll try.
• 17:36
  Dr. Abid Husain: That'll attempt to lower lipid.
• 17:38
  Dr. Abid Husain: Lipid burden.
• 17:39
  Dr. Abid Husain: But the goal is lowering particle numbers and changing the size of the particle, because that's another thing that's really being missed.
• 17:49
  Dr. Abid Husain: LDL particles don't all come in one size and shape.
• 17:52
  Dr. Abid Husain: They vary.
• 17:53
  Dr. Abid Husain: They can be large and buoyant, or they can be small and dense.
• 17:57
  Dr. Abid Husain: And those small and dense ones are the ones that cause plaque.
• 18:01
  Dr. Abid Husain: They cause atherosclerosis.
• 18:03
  Dr. Abid Husain: Well, the liver is where it all comes from.
• 18:05
  Dr. Abid Husain: And if the liver is inflamed, then it's going to make more small dents, LDLs.
• 18:11
  Dr. Abid Husain: So it goes back to doing gastrointestinal testing.
• 18:14
  Dr. Abid Husain: Look at the gut, you know, look at all the other inflammatory markers is there.
• 18:18
  Dr. Abid Husain: If there's inflammation, then that's going to drive up LDLs, and it's going to make those LDLs smaller and more dense and make them more prone to getting inflamed and oxidized.
• 18:27
  Dr. Abid Husain: So, you know, the intervention is going to be things that will lower particle size, lower inflammation, look at their overall metabolism.
• 18:36
  Dr. Abid Husain: So, you know, one of the things that's really been a joy about practicing over the past four, three, four years is the advent of GLP1s.
• 18:45
  Dr. Jill Carnahan, MD: Yeah.
• 18:45
  Dr. Abid Husain: You know, because this has really opened the eyes of the public and cardiologists and everybody that atherosclerosis is a systemic cardiometabolic disease.
• 18:56
  Dr. Abid Husain: It's not a disease of lipids, of cholesterol.
• 19:00
  Dr. Abid Husain: It's a disease that's systemic.
• 19:02
  Dr. Abid Husain: And so we've got to use agents that work on the whole system, and those are fantastic agents that help with lowering adipose tissue, fat tissue, lowering inflammation in the vascular system, as well as helping the liver, helping blood sugar, which, you know, that's what we got to really check, making sure that's intact and stabilized.
• 19:22
  Dr. Abid Husain: So I'll use GLP1s, you know, as a.
• 19:25
  Dr. Abid Husain: Sometimes as a micro dose.
• 19:27
  Dr. Abid Husain: But you know, it's going to be therapeutic for most of my patients because we got to control blood sugar, we got to control inflammatory risk.
• 19:34
  Dr. Abid Husain: And then I'm a big fan of hormones.
• 19:37
  Dr. Abid Husain: I think hormones are our original regenerative tools.
• 19:42
  Dr. Abid Husain: And so when those start to decrease, we lose that regenerative capacity on so many levels from our macroscopic tissue protein deposition all the way down to the cellular level.
• 19:55
  Dr. Abid Husain: So I will test hormones and replace them when appropriate.
• 19:59
  Dr. Abid Husain: So that's sort of the some of the basics that I look at.
• 20:02
  Dr. Abid Husain: And that right there can end up being, you know, very effective.
• 20:06
  Dr. Jill Carnahan, MD: Hey guys, just a quick break to remind you if you haven't yet got a copy of my book Unexpected Finding Resilience through Functional Medicine, Science and Faith.
• 20:14
  Dr. Jill Carnahan, MD: You can find it anywhere books are sold.
• 20:16
  Dr. Jill Carnahan, MD: Grab a copy, share it with a friend.
• 20:18
  Dr. Jill Carnahan, MD: If you prefer audio, you can find that on all audio platforms like Spotify or Audible.
• 20:24
  Dr. Jill Carnahan, MD: I'm that kind of person who likes to walk and run and listen to books on recording.
• 20:29
  Dr. Jill Carnahan, MD: And it's recorded by me.
• 20:31
  Dr. Jill Carnahan, MD: I did it in the recording studio so you'll hear me actually reading the book.
• 20:35
  Dr. Jill Carnahan, MD: Also, if you really want a signed copy, you can get that@drjillhealth.com just in the checkout.
• 20:40
  Dr. Jill Carnahan, MD: Put who you want it endorsed to and I will personally sign that and send it your way.
• 20:45
  Dr. Jill Carnahan, MD: You can also find all kinds of products and services like our Dr. Joe Beauty line@drjillhealth.com yeah.
• 20:52
  Dr. Jill Carnahan, MD: Wow.
• 20:52
  Dr. Jill Carnahan, MD: And so thorough.
• 20:53
  Dr. Jill Carnahan, MD: So I want to talk about a few of those things because you just did an incredible journey about like the.
• 20:57
  Dr. Jill Carnahan, MD: Your mind and how you assess and I think I couldn't agree more on all fronts.
• 21:01
  Dr. Jill Carnahan, MD: So you're saying most people out there, if they haven't got an advanced lipid profile with particle size, they should ask their doctor.
• 21:07
  Dr. Jill Carnahan, MD: I couldn't agree more because it tells you the whole story.
• 21:10
  Dr. Jill Carnahan, MD: I'd love comments about where does you know apoe?
• 21:14
  Dr. Jill Carnahan, MD: Where does apob.
• 21:16
  Dr. Jill Carnahan, MD: Where does LP little a.
• 21:18
  Dr. Jill Carnahan, MD: Where's a few of these other ones that are kind of, I feel like even more powerful alongside that, like that whole panel, Women versus Men.
• 21:25
  Dr. Jill Carnahan, MD: I think there's differential on statins for them and if you have any thoughts about that because I in my experience women have a little bit more risk of diabetes.
• 21:32
  Dr. Jill Carnahan, MD: That Right.
• 21:33
  Dr. Jill Carnahan, MD: So a few little comments about.
• 21:34
  Dr. Jill Carnahan, MD: And you don't have to go deep into the exact numbers or anything but those other markers that people might be out there and have heard about, but they have no idea what they mean.
• 21:42
  Dr. Abid Husain: Sure.
• 21:43
  Dr. Abid Husain: So APOB is the.
• 21:45
  Dr. Abid Husain: Is the way.
• 21:46
  Dr. Abid Husain: The really easy way to measure particles, the total amount of particles that create atherosclerosis.
• 21:53
  Dr. Abid Husain: So it's an easy test.
• 21:55
  Dr. Abid Husain: You can do it along with your lipid panel.
• 21:58
  Dr. Abid Husain: The beauty of APOB is that it measures more than just LDLs, because LDLs are one particle.
• 22:04
  Dr. Abid Husain: And the idea is that every particle of LDL has an APOB protein on it.
• 22:09
  Dr. Abid Husain: And so if you measure the number of APOB proteins, you get an idea what LDL particles there are.
• 22:17
  Dr. Abid Husain: But there are also other particles, not as many of them, that can cause atherosclerosis or contribute to it.
• 22:23
  Dr. Abid Husain: So those can be things like VLDLs or IDLs.
• 22:26
  Dr. Abid Husain: These are the process that the.
• 22:30
  Dr. Abid Husain: These are compounds that make their way slowly to become LDLs.
• 22:34
  Dr. Abid Husain: So APOB measures all of those.
• 22:37
  Dr. Abid Husain: And so getting that tells us, gives us a really good assessment of the number of particles.
• 22:43
  Dr. Abid Husain: Particles actually tell us the number of times something that, you know, the cholesterol particle is going to hit the.
• 22:50
  Dr. Abid Husain: The wall of the artery, and that gives us a better idea of atherosclerosis risk.
• 22:56
  Dr. Abid Husain: And then you can combine LDL with APOB and do a ratio.
• 23:01
  Dr. Abid Husain: And that ratio, if it's greater than 1.2, can give you an indicator that those are larger cholesterol particles that may be less prone to causing plaque.
• 23:11
  Dr. Abid Husain: Lower than 1.2, maybe smaller and dense, more prone to causing plaque.
• 23:15
  Dr. Abid Husain: The other thing you mentioned was LP Little A.
• 23:18
  Dr. Abid Husain: It's getting a lot of attention right now because there's a lot of research into.
• 23:23
  Dr. Abid Husain: Yeah, into.
• 23:24
  Dr. Abid Husain: As a target for atherosclerosis.
• 23:27
  Dr. Abid Husain: You know, I mean, I'm a little.
• 23:28
  Dr. Abid Husain: I'm a little suspect about the.
• 23:30
  Dr. Abid Husain: The therapies because they've been in the pipeline for too long, and they're always about two years out, ever since.
• 23:37
  Dr. Abid Husain: Ever since five years ago.
• 23:38
  Dr. Jill Carnahan, MD: And so what's going on there?
• 23:41
  Dr. Abid Husain: Yeah, whenever something is still doing that, it means that it hasn't met targets, and they might not be as robust as they think is as it might originally thought it would be.
• 23:53
  Dr. Abid Husain: But that being said, LP is a protein that's on the LDL particle.
• 23:58
  Dr. Abid Husain: It makes it more prone to causing plaque and more prone to becoming inflamed.
• 24:03
  Dr. Abid Husain: So when you look at.
• 24:04
  Dr. Abid Husain: They look at genetic studies and it showed that those, the people that have LP do tend to have a higher chance of having atherosclerosis and plaque and calcium on their.
• 24:17
  Dr. Abid Husain: On some of the valves.
• 24:19
  Dr. Abid Husain: There are a few other conditions that are associated with as well, but those are the main ones.
• 24:23
  Dr. Abid Husain: But there's A lot of people that don't have that outcome and they still have LP elevations.
• 24:29
  Dr. Abid Husain: So.
• 24:29
  Dr. Abid Husain: So what's going on there?
• 24:31
  Dr. Abid Husain: The what I'm believing, what I believe and what I'm seeing is that it's more of a risk amplifier.
• 24:38
  Dr. Abid Husain: So if you have existing risk, that would already make you a candidate for atherosclerosis and you have lp, it's going to make that risk amplified, it's going to make it happen faster.
• 24:50
  Dr. Abid Husain: But if you're somebody that's been taking care of yourself, metabolically well balanced, has, you know, does not have inflammation, an elevation of LP should not or may not be as damning or as you know, is not your destiny.
• 25:07
  Dr. Abid Husain: You may not get atherosclerosis as once thought.
• 25:10
  Dr. Abid Husain: So it's more of an amplifier and may not necessarily be a direct contributor to the disease.
• 25:17
  Dr. Jill Carnahan, MD: Okay, well, that was so eloquent.
• 25:19
  Dr. Jill Carnahan, MD: That might be one of the most eloquent, easy to understand ways that I've ever had a guest explain.
• 25:23
  Dr. Jill Carnahan, MD: And thank you for doing that because I know a lot of you out there, even doctors that are, you know, general practitioners, I think, don't really get it.
• 25:29
  Dr. Jill Carnahan, MD: So thank you, because we have a lot of them listening, too.
• 25:32
  Dr. Jill Carnahan, MD: One of the thought is, obviously you can check oxidized LDL directly.
• 25:36
  Dr. Jill Carnahan, MD: How would that Compare to the VLDLs and the ideals and the lower dense?
• 25:40
  Dr. Jill Carnahan, MD: Like, are those both similar in how they're dangerous, or is that a different kind of pattern?
• 25:46
  Dr. Jill Carnahan, MD: The.
• 25:46
  Dr. Jill Carnahan, MD: If the true oxidized ldl.
• 25:48
  Dr. Abid Husain: Yeah, if it's.
• 25:49
  Dr. Abid Husain: That's probably.
• 25:50
  Dr. Abid Husain: It's a different pattern because they've made their way to LDL and now they're becoming oxidized.
• 25:54
  Dr. Abid Husain: So that's something that is more prone to.
• 25:58
  Dr. Abid Husain: To getting into the arterial wall and then also amplifying the immune system in that specific area.
• 26:06
  Dr. Abid Husain: The oxidized LDL measurement is useful, especially mostly when it's positive, because when we know that it's positive, then we know that there's some sort of amplification of the immune system and specifically happening in the plaque.
• 26:21
  Dr. Abid Husain: You can have a normal oxidized LDL and still have amplification and presence of oxidized LDL in the plaque, mostly because it concentrates there and sometimes at lower levels.
• 26:34
  Dr. Abid Husain: We don't see it in the serum, but we see it, but it's still.
• 26:37
  Dr. Abid Husain: It's been detected in the plaque.
• 26:39
  Dr. Abid Husain: So a negative oxidized ldl, maybe, you know, you still may want to look at the other markers and see if there's other potential inflammatory markers that may convince you.
• 26:53
  Dr. Abid Husain: That there's still got to be concerned.
• 26:55
  Dr. Abid Husain: If it's positive, then that's a definite flag that something is brewing and this person's hot.
• 27:01
  Dr. Jill Carnahan, MD: Okay, once again, super helpful.
• 27:03
  Dr. Jill Carnahan, MD: So you talked about environmental toxicity.
• 27:05
  Dr. Jill Carnahan, MD: I love that you mentioned testing that.
• 27:07
  Dr. Jill Carnahan, MD: Because I would love your comments as a cardiologist on nanoparticulate plastics.
• 27:13
  Dr. Jill Carnahan, MD: How much are you seeing mold?
• 27:15
  Dr. Jill Carnahan, MD: How much are you seeing toxicity?
• 27:16
  Dr. Jill Carnahan, MD: Metals you mentioned before.
• 27:17
  Dr. Jill Carnahan, MD: But.
• 27:18
  Dr. Jill Carnahan, MD: And what of all of those is the most damning for cardiac health?
• 27:22
  Dr. Abid Husain: Yeah.
• 27:25
  Dr. Abid Husain: So what seems to be.
• 27:28
  Dr. Abid Husain: The data is supporting that.
• 27:30
  Dr. Abid Husain: What seems to be making its way up the risk category is actually air pollution and particulate matter.
• 27:36
  Dr. Jill Carnahan, MD: Yeah.
• 27:37
  Dr. Abid Husain: And it's, and it's the really fine particulate air matter that's really causing a problem.
• 27:42
  Dr. Abid Husain: And that's coming from industrial sources.
• 27:45
  Dr. Abid Husain: You know, it's, you know, campfires are great and they're not going to cause a lot of really particulate matter because.
• 27:51
  Dr. Abid Husain: Because that's larger stuff.
• 27:53
  Dr. Abid Husain: You know, it's still, it's, that's, it's fun to hang out a camp at a campfire.
• 27:57
  Dr. Abid Husain: Nobody wants to breathe in smoke.
• 27:58
  Dr. Abid Husain: And you're probably okay if you're there.
• 28:00
  Dr. Abid Husain: But.
• 28:01
  Dr. Abid Husain: And it's also what they're burning.
• 28:02
  Dr. Jill Carnahan, MD: Yeah.
• 28:03
  Dr. Abid Husain: Burning is wood, which is, you know, there.
• 28:05
  Dr. Abid Husain: It's.
• 28:06
  Dr. Abid Husain: Anyway, it's less toxic, for sure.
• 28:08
  Dr. Abid Husain: It's the industrially produced really fine particulate matter that's problematic.
• 28:14
  Dr. Abid Husain: Exhaust from cars, you know, that's where we're seeing cardiovascular risk go up.
• 28:20
  Dr. Abid Husain: Because what that does is it gets into the lungs and it also can pass through into the bloodstream and start making its way as an irritant.
• 28:28
  Dr. Abid Husain: And it's a really potent irritant as well.
• 28:32
  Dr. Abid Husain: Microplastics are interesting.
• 28:34
  Dr. Abid Husain: There's data to go in both ways.
• 28:38
  Dr. Abid Husain: Now we see microplastics showing up.
• 28:41
  Dr. Abid Husain: There was a study that caused a big stir, I think, last year, where they took plaque, atherosclerotic plaque and found microplastics in the plaque.
• 28:52
  Dr. Jill Carnahan, MD: Yes.
• 28:52
  Dr. Jill Carnahan, MD: I remember seeing that.
• 28:53
  Dr. Jill Carnahan, MD: It was like crazy.
• 28:55
  Dr. Abid Husain: So, so it's so, you know, those are so small and so fine that they can make their way into these cellular spaces.
• 29:04
  Dr. Abid Husain: Now, is it activating the immune system?
• 29:09
  Dr. Abid Husain: There's data to go both ways.
• 29:10
  Dr. Abid Husain: You know, there was a really interesting lecture I saw at one of the longevity conferences where somebody was talking about microplastics.
• 29:19
  Dr. Abid Husain: And they said that they have not been able to detect a lot of inflammatory burden, even though in patients that have had high detected plastic levels.
• 29:31
  Dr. Abid Husain: So we see that.
• 29:32
  Dr. Abid Husain: But Then at the same time we know that having plastic is a endocrine disruptor.
• 29:40
  Dr. Abid Husain: Is, you know, it's not, it's foreign to the body and it's hard to imagine that it's not going to trigger something.
• 29:46
  Dr. Abid Husain: And at the least as an endocrine disruptor, it may inhibit nitric oxide, it may inhibit some of the natural, you know, defense mechanisms that we have that are hormonal, not to mention estradiol, testosterone, things like that.
• 30:01
  Dr. Abid Husain: So I err on the side of it being something we got to be cautious about and be careful not to get too much exposure to.
• 30:08
  Dr. Jill Carnahan, MD: What a great overview.
• 30:09
  Dr. Jill Carnahan, MD: And I couldn't agree more.
• 30:10
  Dr. Jill Carnahan, MD: And I think the other difficulty is a lot of our great toxin panels aren't yet measuring plastic.
• 30:15
  Dr. Jill Carnahan, MD: So we don't really, I don't think know, except for the research that's coming out of how much our patients really, you know, have exposure.
• 30:22
  Dr. Jill Carnahan, MD: I want to talk about hormones and peptides, you and I love that topic.
• 30:25
  Dr. Jill Carnahan, MD: Before I do, I want to just like maybe get the top five or six or 10, a few of the interventions.
• 30:30
  Dr. Jill Carnahan, MD: If you have someone where you have this known, you know, oxidized LDL or elevated APOB or any of these markers and they're maybe you might put on a statin.
• 30:39
  Dr. Jill Carnahan, MD: And I couldn't agree with you more.
• 30:40
  Dr. Jill Carnahan, MD: There is a perfectly appropriate use for those drugs for that.
• 30:43
  Dr. Jill Carnahan, MD: But maybe you're going to first do some natural things.
• 30:45
  Dr. Jill Carnahan, MD: What kinds of things do you really like as far as nutraceuticals for coronary artery disease?
• 30:51
  Dr. Abid Husain: Yeah, so nutraceuticals, I like to use bergamot.
• 30:56
  Dr. Abid Husain: That's one of my first starting agents.
• 31:00
  Dr. Abid Husain: And I'll use anywhere from 800 milligrams or higher.
• 31:04
  Dr. Abid Husain: Sometimes you have to double the dose that might be recommended to get to that range.
• 31:10
  Dr. Abid Husain: So bergamot is a, it's a citrus peel extract.
• 31:18
  Dr. Abid Husain: And so it's got a lot of polyphenols.
• 31:20
  Dr. Abid Husain: It's basically a polyphenol.
• 31:22
  Dr. Abid Husain: A lot of antioxidants, a lot of, you know, systemic benefits to it.
• 31:27
  Dr. Abid Husain: I start with that.
• 31:28
  Dr. Abid Husain: I will try sometimes adding something called citronol to it, which is another, it's another, you know, orange based extract from a different part of the orange and a different type of species.
• 31:40
  Dr. Abid Husain: They work well together because they're not the same pathways.
• 31:44
  Dr. Abid Husain: What's interesting about bergamot is that it works on a similar pathway as a statin does.
• 31:49
  Dr. Abid Husain: Hmg, coenzyme, a reductase pathway.
• 31:51
  Dr. Abid Husain: But because it's a polyphenol, it also has a whole host of anti inflammatory effects that it can provide.
• 31:59
  Dr. Abid Husain: And then citronol doesn't really work on that enzyme.
• 32:03
  Dr. Abid Husain: So it's a different pathway.
• 32:04
  Dr. Abid Husain: Citronol is a combination of nobelatin and tangeretin.
• 32:07
  Dr. Abid Husain: So you can tell by the name that they're all sort of citrus based.
• 32:11
  Dr. Abid Husain: But the combination of the two can bring down LDLs cholesterol and reduce inflammatory burden.
• 32:19
  Dr. Abid Husain: The other nutraceutical that I tend to use is aged garlic extract.
• 32:24
  Dr. Abid Husain: And so that really hits that oxidized LDL process.
• 32:28
  Dr. Abid Husain: It really lowers that as well.
• 32:31
  Dr. Abid Husain: I do not use red yeast rice because it's too unpredictable.
• 32:36
  Dr. Abid Husain: We don't know what the actual ingredients are.
• 32:39
  Dr. Abid Husain: And the actual ingredient was actually removed many, you know, like, yeah, three, four, a few decades ago.
• 32:45
  Dr. Abid Husain: So it's still a popular nutraceutical, but it really doesn't have a lot of efficacy anymore.
• 32:51
  Dr. Jill Carnahan, MD: Oh, wonderful.
• 32:52
  Dr. Jill Carnahan, MD: I love that list.
• 32:53
  Dr. Jill Carnahan, MD: I couldn't agree more.
• 32:54
  Dr. Jill Carnahan, MD: Hormones and peptides in our last maybe five minutes.
• 32:56
  Dr. Jill Carnahan, MD: That's a whole nother topic.
• 32:57
  Dr. Jill Carnahan, MD: It's been an hour, right?
• 32:58
  Dr. Jill Carnahan, MD: I'm like, okay, sorry.
• 32:59
  Dr. Jill Carnahan, MD: But give us a little overview.
• 33:01
  Dr. Jill Carnahan, MD: Men and women, obviously we have like andropause and menopause and what are some of the most powerful interventions for men and women with the hormone therapies?
• 33:10
  Dr. Abid Husain: Yeah, well it's powerful for both men and women to use testosterone and estradiol.
• 33:15
  Dr. Abid Husain: And I think that the weight of the two is different in this, in either sex.
• 33:21
  Dr. Abid Husain: So for women, estradiol is far more important than the testosterone.
• 33:25
  Dr. Abid Husain: And we have data that shows that estradiol is the primary hormone that helps their cardiovascular health, helps their vascular health, helps brain health, metabolic health.
• 33:38
  Dr. Abid Husain: It specifically helps HDL's and helps reverse cholesterol transportation.
• 33:43
  Dr. Abid Husain: So there's just, we can, we could go on for hours talking about how estradiol is important.
• 33:47
  Dr. Abid Husain: Women don't have as high of a testosterone peak and so they do need steady testosterone.
• 33:54
  Dr. Abid Husain: The data on how much testosterone helps the vascular system in women is not quite as clear, but we do know it helps and it also helps the metabolic health with the muscular system and glucose regulation.
• 34:08
  Dr. Abid Husain: So men on the other hand, they rely on both, but probably testosterone a little bit more.
• 34:15
  Dr. Abid Husain: So men, for testosterone, I replace that because it really amplifies nitric oxide, helps vascular health, reduces inflammation in the vascular system.
• 34:26
  Dr. Abid Husain: And it may because men get that higher peak.
• 34:29
  Dr. Abid Husain: And that higher peak is where we start to see a lot of those benefits happen with testosterone now it gets converted to estradiol.
• 34:37
  Dr. Abid Husain: And men need estradiol as well.
• 34:39
  Dr. Abid Husain: They need it for HDL function.
• 34:42
  Dr. Abid Husain: They need it to balance some of the peaks of testosterone.
• 34:45
  Dr. Abid Husain: And interestingly enough, estradiol is important for libido.
• 34:50
  Dr. Abid Husain: Testosterone is not the only thing.
• 34:52
  Dr. Abid Husain: So you can have a man that has great testosterone, but if their estradiol is low because they've been taking estrogen blockers, it can negatively impact their libido.
• 35:02
  Dr. Jill Carnahan, MD: Wow.
• 35:02
  Dr. Abid Husain: Yeah.
• 35:03
  Dr. Abid Husain: So.
• 35:03
  Dr. Abid Husain: So I make sure not to have any of my men on anastrozole or any of those estrogen blockers.
• 35:08
  Dr. Abid Husain: I want estradiol to be balanced.
• 35:10
  Dr. Abid Husain: And if it's high, as long as they're not having symptoms, that's great, because then I know their HDLs are being more.
• 35:16
  Dr. Abid Husain: More optimized, and then they're getting the benefit of testosterone to.
• 35:20
  Dr. Abid Husain: To help the vascular system and the endothelium.
• 35:23
  Dr. Jill Carnahan, MD: Wow.
• 35:24
  Dr. Jill Carnahan, MD: I love that perspective.
• 35:25
  Dr. Jill Carnahan, MD: I could not agree more.
• 35:26
  Dr. Jill Carnahan, MD: But there is very few regenerative medicine physicians or personalized performance doctors out there talking about that.
• 35:33
  Dr. Jill Carnahan, MD: And what I've seen is men with like, estrogen of 0, they have a lot of problems.
• 35:37
  Dr. Jill Carnahan, MD: Yeah, not a good thing.
• 35:39
  Dr. Abid Husain: Yeah, it's a easy way to get early disease, early atherosclerosis.
• 35:43
  Dr. Jill Carnahan, MD: Oh, my goodness, that's so powerful.
• 35:45
  Dr. Jill Carnahan, MD: Okay, last couple minutes.
• 35:46
  Dr. Jill Carnahan, MD: Peptides, once again, talk forever.
• 35:48
  Dr. Jill Carnahan, MD: And we both love this topic.
• 35:49
  Dr. Jill Carnahan, MD: But what are your top three favorite peptides and.
• 35:53
  Dr. Jill Carnahan, MD: And their use?
• 35:55
  Dr. Abid Husain: Yeah, well, the.
• 35:57
  Dr. Abid Husain: The most.
• 35:58
  Dr. Abid Husain: The three that I use the most often, I think are the most versatile, are really common ones.
• 36:02
  Dr. Abid Husain: It's BPC, Thymus, and Beta 4.
• 36:05
  Dr. Abid Husain: I use those in pairing in combination so much.
• 36:09
  Dr. Abid Husain: Whether it's recovering from an injury, whether it is optimizing vascular health, whether it's somebody that I think has some sort of.
• 36:18
  Dr. Abid Husain: They we need to stimulate, maybe some stem cells or some sort of regenerative capacity.
• 36:23
  Dr. Abid Husain: From a cardiovascular standpoint, you know, there's some great data about TB4 and also fibrosis, so I like it.
• 36:31
  Dr. Abid Husain: For hypertension, combining TB4 with some other antihypertensives can really amplify anti hypertensive effects and reduce fibrosis.
• 36:40
  Dr. Abid Husain: So the scarring that can happen in the vascular tissue.
• 36:44
  Dr. Abid Husain: And then the third one that I would add is Tessamorel and Ipamorel.
• 36:48
  Dr. Abid Husain: I like that combination because there's data to support that.
• 36:52
  Dr. Abid Husain: We reduce the thickness of the lining of the artery, help vascular health.
• 36:57
  Dr. Abid Husain: And then there's all the metabolic health that happens with weight loss.
• 37:01
  Dr. Abid Husain: Optimizing growth hormone.
• 37:03
  Dr. Abid Husain: And then, you know, growth hormone also optimizes mitochondrial function.
• 37:06
  Dr. Abid Husain: So there's just, you know, it's a really fantastic.
• 37:10
  Dr. Abid Husain: Just those three are really fantastic trio that tend to do a lot of help for a lot of people.
• 37:16
  Dr. Jill Carnahan, MD: Once again, I couldn't agree more.
• 37:18
  Dr. Jill Carnahan, MD: Dr. Hussain.
• 37:19
  Dr. Jill Carnahan, MD: This was a great, jam packed, powerful interview.
• 37:22
  Dr. Jill Carnahan, MD: One of my favorites.
• 37:23
  Dr. Jill Carnahan, MD: And it's always good to see you friend and colleague and see what you're doing in the world.
• 37:27
  Dr. Jill Carnahan, MD: If people want to find out more about you're now practicing in Boulder.
• 37:30
  Dr. Jill Carnahan, MD: Do you want to tell people more about your website where they can find you or if they want to see you or your clinic?
• 37:34
  Dr. Abid Husain: Yeah, absolutely.
• 37:35
  Dr. Abid Husain: I'm at Boulder Longevity Institute.
• 37:37
  Dr. Abid Husain: You can, the website's great.
• 37:40
  Dr. Abid Husain: You can just sign up and register on the website.
• 37:43
  Dr. Abid Husain: Somebody will give you a call and give you all the information about how to see me.
• 37:48
  Dr. Abid Husain: So I have a website there.
• 37:49
  Dr. Abid Husain: I also have a website where I've got a recent cardiology course that's been released.
• 37:56
  Dr. Abid Husain: So that's.
• 37:57
  Dr. Abid Husain: Yeah.
• 37:58
  Dr. Abid Husain: And that's open to all comers.
• 38:00
  Dr. Abid Husain: It's specifically designed for practitioners but if you're interested and want to learn, it's open to anybody.
• 38:05
  Dr. Abid Husain: And that's at Next Generation Medicine.
• 38:08
  Dr. Abid Husain: And then I'm on Instagram and I got a YouTube channel that I, you know, that I put information out there just like this whenever I can.
• 38:16
  Dr. Jill Carnahan, MD: Awesome.
• 38:16
  Dr. Jill Carnahan, MD: You are incredibly articulate on this and I love this interview.
• 38:20
  Dr. Jill Carnahan, MD: So guys, if you're riding your car, doing a run, hopefully something athletic out there and you aren't taking notes, don't worry, all of this will be in the show notes.
• 38:29
  Dr. Jill Carnahan, MD: Dr. Hussain, what a pleasure and an honor and thank you for coming on the show.
• 38:33
  Dr. Abid Husain: Thanks for having me, Joe.
• 38:34
  Dr. Jill Carnahan, MD: Hey guys, hope you enjoyed that interview with Dr. Abid Hussain who is a colleague and friend and just have the deepest admiration for him as a cardiologist and now into longevity and regenerative medicine.
• 38:44
  Dr. Jill Carnahan, MD: Hope you enjoyed that chock full interview of great information.
• 38:48
  Dr. Jill Carnahan, MD: If you like this episode, please do share it with someone you know that might benefit.
• 38:52
  Dr. Jill Carnahan, MD: Hit the subscribe button on YouTube.
• 38:54
  Dr. Jill Carnahan, MD: We are getting close to a million subscribers and I would love to ask you to help us reach that goal in the next few months.
• 39:00
  Dr. Jill Carnahan, MD: You can also give us a review if you're listening on itunes or Spotify.
• 39:05
  Dr. Jill Carnahan, MD: And as always, we have new episodes coming out every week.
• 39:07
  Dr. Jill Carnahan, MD: So I will see you again next week for a new episode of Resiliency Radio.
• 39:12
  Dr. Jill Carnahan, MD: Until then, make it a great day.