876-NeMO: Compendium for Neocortical Development Exploration

Paper Talk · Apr 30, 2026 · 20m

This study introduces NeMO Analytics, a web-based platform designed to consolidate and analyze vast amounts of transcriptomic data concerning the development of the mammalian neocortex. By integrating information from hundreds of public studies, the researchers created a curated environment that allows users to explore gene expression across multiple species, including mice, macaques, and humans. The authors utilized a mathematical method called joint matrix decomposition to identify shared molecular programs that drive the transition from neural progenitor cells to mature neurons. Their…