084-CellForge: Agentic Design of Virtual Cell Models
The paper introduces CellForge, an innovative agentic system designed for autonomously creating virtual cell models to predict cellular responses to various biological perturbations. This system employs a multi-agent framework, where specialized AI agents collaborate across three core modules: Task Analysis (characterizing datasets and retrieving literature), Method Design (developing optimized modeling strategies through expert discussion), and Experiment Execution (generating and validating executable code). CELLFORGE consistently outperforms existing methods in diverse perturbation…
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