Could Parkinson's start in the gut? | Kathleen Poston

From Our Neurons to Yours · Apr 16, 2026 · 41m

Traditionally, we think of Parkinson's as a movement disorder—defined by slowed movement, stiff muscles, and involuntary shaking. But it turns out there are other symptoms that appear years or even decades before movement problems bring patients to the clinic: sleep disturbances, chronic constipation, and loss of smell.

For today's guest, these early symptoms represent an incredible opportunity to understand where Parkinson's begins and to identify patients much earlier in the disease.

Kathleen Poston is a neurologist and division chief for movement disorders at Stanford Medicine. She's also…