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Dr. Sangeetha Reddy & Dr. Ahmed Elkhanany - First-Line ADCs IN Metastatic Triple-Negative Breast Cancer
What should replace chemotherapy in the first-line treatment of immunotherapy-ineligible metastatic triple-negative breast cancer(TNBC)?
Dr. Sangeetha Reddy and Dr. Ahmed Elkhanany discuss the evolving role of antibody-drug conjugates (ADCs) following the recent approval of datopotamab deruxtecan (Dato-DXd) and the growing evidence supporting ADCs over traditional chemotherapy in metastatic TNBC.
The conversation explores efficacy data, overall survival outcomes, toxicity management, patient selection, and the practical implications of incorporating multiple TROP2-directed ADCs into clinical…
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