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S7 Ep9: Test First, Treat Second: ASCO's Updated Approach to Driver Mutation–Negative NSCLC

In this minisode, we break down the latest update to ASCO's living guideline for stage IV non–small cell lung cancer (NSCLC) without driver mutations — and what it means for clinicians on the front lines of care.

We're drawing on a conversation with Dr. Joshua Reuss, thoracic medical oncologist at Georgetown University and co-chair of ASCO's Living Guidance Committee, who helped explain the key changes, the remaining uncertainties, and where the field is heading.

What changed — and why now? This was a scheduled comprehensive review, not triggered by a single trial or approval. The committee…

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