1606-Trinity Nanoplatform for Integrated Cancer Theranostics
The paper describes the creation of an integrated theranostic nanoplatform designed to advance precision cancer care by combining diagnosis and treatment into a single system. Researchers developed nanoparticles labeled with the radionuclide 68Ga and a near-infrared fluorophore, which allow for rapid PET/CT imaging and real-time fluorescence-guided surgery. Beyond mapping tumors, the platform utilizes AIE-active photosensitizers to deliver photodynamic and photothermal therapies, effectively killing residual cancer cells through localized heat and reactive oxygen species. Testing in mouse…
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