HER2-Positive Metastatic Breast Cancer — An Interview with Prof Dr Sibylle Loibl on First-Line and Maintenance Therapy (Companion Faculty Lecture)

Research To Practice | Oncology Videos · Jul 17, 2026 · 30m

Featuring a slide presentation and related discussion from Prof Dr Sibylle Loibl, including the following topics:

· Overview of the changing landscape of treatment for patients with HER2-positive metastatic breast cancer (mBC) (0:00)

· Results from the CLEOPATRA, PATINA and HER2CLIMB-05 trials of first-line treatment and maintenance approaches for HER2-positive mBC (5:26)

· Efficacy and safety findings from the Phase III DESTINY-Breast09 trial comparing trastuzumab deruxtecan with or without pertuzumab to taxane/trastuzumab/pertuzumab as first-line therapy for HER2-positive mBC (14:56)

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