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Advances in Guillain-Barré Syndrome: Diagnosis, Biomarkers, and Management
This comprehensive medical review examines recent developments in the diagnosis, pathophysiology, and management of Guillain-Barré syndrome (GBS), an autoimmune disorder causing acute paralysis. The authors highlight a transition toward a molecular understanding of the disease, emphasizing the role of antecedent infections like Campylobacter jejuni and the identification of specific anti-ganglioside antibodies. While the text reviews established prognostic models and emerging fluid biomarkers like neurofilament light chain, it acknowledges that GBS remains primarily a clinical diagnosis…
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