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Erbb4 Protein Linked to Alzheimer's Progression | South Korea News

Scientists in Korea have uncovered a key protein, Erbb4, that acts as a central trigger in early Alzheimer’s disease. When levels of this protein go haywire in excitatory brain cells, it causes overactivity, disrupts neuron connections, fuels inflammation, and accelerates amyloid plaque buildup—all hallmarks of the disease. In groundbreaking mouse studies, turning down Erbb4 reversed symptoms like memory loss and reduced plaques, while boosting it mimicked Alzheimer’s. Human data confirms higher Erbb4 correlates with worse disease progression. This discovery points to a promising new…

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