444-The Mouth Bacterium Fueling Colorectal Cancer
This comprehensive review identifies Fusobacterium nucleatum as a critical pathobiont that transitions from a common oral resident to a driver of systemic disease. The text explains how this bacterium uses specialized adhesins and metabolites to migrate and thrive in diverse environments, particularly the gastrointestinal tract. Research highlights a profound link between the microbe and colorectal cancer, where it promotes tumor growth, immune evasion, and resistance to chemotherapy. Beyond oncology, the sources associate the pathogen with inflammatory bowel disease, adverse pregnancy…
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