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Serum NFL as a biomarker for CIDP Diagnosis and Treatment
This scientific study investigated the use of serum neurofilament light chain (sNFL), particularly when adjusted for age and BMI as z-scores (zNFL), as a biomarker for chronic inflammatory demyelinating polyneuropathy (CIDP). Analyzing a large cohort of patients with immune-mediated neuropathies, the researchers found that elevated zNFL correlated with increased disease severity in patients with typical CIDP, especially in the early stages of the illness. A zNFL score above 2 in the early phase of typical CIDP was associated with more severe motor dysfunction and a lack of response to initial…
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