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1648-Nanoplatform for Tendinopathy Treatment

Researchers have developed a multifunctional nanoplatform, known as MSM-DTM, designed to comprehensively treat tendinopathy by targeting the disease's core pathological components. This technology combines hybrid membrane vesicles—fused from macrophage and sensory neuron membranes—with a decellularized tendon matrix scaffold to create a pro-regenerative environment. The platform functions as a molecular sponge, effectively absorbing harmful inflammatory cytokines and pain-triggering neuropeptides to alleviate chronic discomfort. By inhibiting the abnormal activation of the JAK-STAT signaling…

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