His Pacing vs Biventricular Pacing for Cardiac Resynchronization Therapy | JACC: Clinical Electrophysiology

JACC Specialty Journals · Apr 13, 2026 · 2m

In this episode, Dr. Kenneth Ellenbogen, Deputy Editor of JACC: Clinical Electrophysiology, discusses new long-term findings from the His-Alternative I trial, the first European randomized study comparing His-bundle pacing with conventional biventricular pacing for cardiac resynchronization therapy (CRT). He highlights five-year outcomes demonstrating that when His-bundle pacing is achieved with low implant thresholds, its long-term performance—including lead stability, generator replacements, and clinical response—closely mirrors that of biventricular CRT. Dr. Ellenbogen explores the…