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TIGRIS trial

In this episode, we discuss the recently published Tigris trial, which evaluated the role of Polymyxin B hemoadsorption in patients with septic shock. We explore the trial’s rationale, trace the evolution of evidence in this area, examine its analytical approach (Bayesian vs. frequentist), and unpack the results. We also discuss the study’s strengths and limitations, and highlight the key takeaways.

The skinny

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