Berberine, Bergamot, Red Yeast Rice, or Plant Sterols — What Actually Works?

Heart Health, Reimagined with Dr. Mona Shah, MD · Oct 8, 2026 · 18m · transcript

Can supplements really replace a statin? In this video I break down the four natural options I get asked about most for lowering LDL and ApoB - red yeast rice, berberine, bergamot, and plant sterols - what the evidence actually shows for each one, and who might genuinely be a good candidate for a natural-first approach versus who needs more than a supplement can offer.

I also cover why I stopped recommending niacin, whether you can safely combine these supplements, and the exact framework I use with my own patients to decide how much treatment someone actually needs.

I'm Dr. Mona Shah, a…