562-Meningeal Vessel Blockage Enhances Anti-GBM Immunity
Research presented in these documents identifies the dura mater as a vital hub for regulating anti-tumor immunity within the central nervous system. Scientists developed a surgical technique called meningeal blood vessel blockage (MBB) to selectively restrict blood flow to the dura without harming the brain's internal tissues. This procedure successfully suppressed glioblastoma (GBM) growth by altering the balance of border-associated macrophages (BAMs), favoring a specific resident population with superior antigen-presenting capabilities. High levels of these specialized macrophages…
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