Latest / Ridiculous History / A Ridiculous History of Brain Science, with Jorge Cham
Transcript
- 0:00Speaker 1: Ridiculous History is a production of iHeartRadio. Welcome back to
- 0:27Speaker 1: the show. Thank you, as always so much Ridiculous Historians
- 0:31Speaker 1: for joining us. Let's hear it for the man the
- 0:34Speaker 1: myth our super producer mister Max Williams Imax. All right, yeah,
- 0:40Speaker 1: we're getting some snapping fingers. This is part two of
- 0:44Speaker 1: a continuing exploration. The guy who just said Imax is
- 0:48Speaker 1: mister Noel Brown, none other than.
- 0:51Speaker 2: Oh thanks buddy, You're welcome, Buckeroo.
- 0:54Speaker 1: They called me Ben Bullen in this part of the world,
- 0:57Speaker 1: and Noel, if we could do a previous on Ridiculous History,
- 1:05Speaker 1: the smoke Monster was bullsh wasn't anything, well, it was
- 1:10Speaker 1: the thing. It was the man in Black, it was
- 1:12Speaker 1: you know, that's the show Lost, which dated references.
- 1:17Speaker 2: But that's what we're here for. No, it's true.
- 1:19Speaker 3: We did previously on Ridiculous History talk with the brilliant
- 1:24Speaker 3: and lovely doctor Jorge at Sham, who helped us navigate
- 1:28Speaker 3: the universe a little bit, from the Big Bang to
- 1:31Speaker 3: the singularities to AI and the way that artificial intelligence
- 1:37Speaker 3: may well be close to, if not already at a
- 1:40Speaker 3: place where it resembles the human brain.
- 1:44Speaker 1: Yes, that is true. And Noel, as you know, I'm
- 1:47Speaker 1: really proud of you and Maxim myself for being quite
- 1:52Speaker 1: transparent and forthright with the fact that we are ourselves
- 1:57Speaker 1: not experts.
- 1:58Speaker 2: Folks.
- 2:00Speaker 1: We know everybody enjoyed the first part of our conversations
- 2:04Speaker 1: with doctor or a Champ, and believe it or not,
- 2:08Speaker 1: we were able to get Orgey back for another episode
- 2:14Speaker 1: or Hey, welcome, thank you for joining us.
- 2:17Speaker 4: Hey, super fun to be here. Thanks for having me back.
- 2:20Speaker 3: Of course, of course you're helping us out as well.
- 2:24Speaker 3: We love a good two part, especially one that we
- 2:26Speaker 3: decide on in advance.
- 2:27Speaker 4: Yeah, and this will be the Empire Streks back of podcasts.
- 2:31Speaker 2: Oh, that's the film. It's a universe.
- 2:42Speaker 1: We're talking about the history of what we call the
- 2:45Speaker 1: Big Bang in our previous exploration, which led us to,
- 2:50Speaker 1: as you were saying, Noel, an exploration of so called
- 2:54Speaker 1: artificial intelligence, the nature of reality, the observable universe. And
- 2:59Speaker 1: we tease just a bit episode two. This is our
- 3:05Speaker 1: exploration of the ridiculous history of a thing that studies
- 3:12Speaker 1: itself the science of the human brain. So real quick
- 3:17Speaker 1: I could if we could open it up this way, Orgey,
- 3:22Speaker 1: just small talk, What is the human brain.
- 3:28Speaker 4: Was this little about sixty eight pound organ that you
- 3:31Speaker 4: have in your head. And it's just another organ in
- 3:34Speaker 4: your head.
- 3:34Speaker 1: You know.
- 3:34Speaker 4: It's a lump of fleshy stuff that basically makes who
- 3:39Speaker 4: you are happen, Like your conscious experience, all your memories,
- 3:44Speaker 4: how you feel, that's all happening in that little gelatinous
- 3:48Speaker 4: blob inside your skull.
- 3:50Speaker 3: I've always felt calling the brain an organ was selling
- 3:53Speaker 3: it short just a little bit. When I think of
- 3:55Speaker 3: an organ, I guess I think of just like guts.
- 3:57Speaker 3: You know, it's important. But the brain is a very
- 4:01Speaker 3: peculiar and powerful and incredible organ.
- 4:04Speaker 4: It is it is. People say it's the most complex
- 4:07Speaker 4: organization of matter that we know about in the whole universe.
- 4:11Speaker 2: And it's also the biggest erogenoist zone.
- 4:14Speaker 4: In the human we go. It's the biggest everything zone.
- 4:17Speaker 4: Basically hunger, heye, love, it's all happening in your head.
- 4:21Speaker 1: Now, this is fascinating. I love that phrase because we
- 4:25Speaker 1: also have to acknowledge an inherent dilemma. We're asking a
- 4:31Speaker 1: thing to research and explain itself, to measure itself. Could
- 4:37Speaker 1: you tell us a little bit about the philosophical quandaries
- 4:43Speaker 1: involved with that like because ordinarily, you know, if you
- 4:47Speaker 1: asked if you asked a duck its opinion about ducks,
- 4:53Speaker 1: you would get a weird you know, not completely objective.
- 4:58Speaker 4: Right, right, right, and everyone knows are just a bunch
- 5:00Speaker 4: of quacks. Now it's a super interesting philosophical conversation, right,
- 5:11Speaker 4: because right, there's eighty six billion neurons in your head,
- 5:15Speaker 4: and so the idea that eighty six billion neurons could
- 5:18Speaker 4: ever really really understand what's happening in eighty six billion neurons,
- 5:23Speaker 4: even if somebody else's eighty six billionaires, it's sort of impossible, right.
- 5:26Speaker 4: It's sort of like a car understanding a car, or
- 5:28Speaker 4: you know, a switch understanding a switch. So it's probably
- 5:32Speaker 4: not possible for the human brain to really understand everything
- 5:35Speaker 4: that's going on in your brain, like down to the tee.
- 5:38Speaker 4: But you know, we have science, and so we can
- 5:41Speaker 4: make kind of generalizations, we can make certain rules, we
- 5:44Speaker 4: can understand the general structure and organization of the brain,
- 5:48Speaker 4: but like totally understanding the brain and predicting what it's
- 5:52Speaker 4: going to do, it's probably impossible for our brains. But
- 5:54Speaker 4: you can imagine, like maybe aliens who have four hundred
- 5:58Speaker 4: billion neurons, you know them, we might be like, oh,
- 6:01Speaker 4: look at these cats, you know, running around, We can
- 6:03Speaker 4: totally understand what's going on in their heads.
- 6:06Speaker 1: So this leads us to the ridiculous history of neuroscience
- 6:11Speaker 1: or brain science. Could you tell us a little bit
- 6:14Speaker 1: about the first I guess there was a moment in
- 6:20Speaker 1: human civilization, or a series of moments more accurately, wherein
- 6:25Speaker 1: people realized this gelatinous blob in their head was doing something.
- 6:31Speaker 1: We're under the impression that for a lot of human history,
- 6:36Speaker 1: various cultures believed that the soul or the consciousness maybe
- 6:41Speaker 1: resided in other organs, like the heart or the I'll
- 6:46Speaker 1: say it, sorry, substitute teachers, genitalia.
- 6:52Speaker 4: Was there a lot of it? A lot of our
- 6:54Speaker 4: actions do come.
- 6:55Speaker 2: From it's like a second brain.
- 7:00Speaker 1: So what was there any sort of inflection point or
- 7:06Speaker 1: crossroads in history of humans where they started to look
- 7:11Speaker 1: at the brain as a seat of consciousness.
- 7:15Speaker 4: Yeah, yeah, now, yeah, it's a pretty interesting history because,
- 7:19Speaker 4: as you mentioned, probably for most of human history, we
- 7:22Speaker 4: had no idea what was going on inside of our bodies.
- 7:24Speaker 4: How though our bodies work, much less how our brains
- 7:27Speaker 4: worked or what it did Aristotle back in the ancient
- 7:31Speaker 4: Greek era. Uh, basically agree with what you just said,
- 7:35Speaker 4: which is he thought that everything that makes us who
- 7:38Speaker 4: we are is in our hearts, like in our chest.
- 7:41Speaker 4: And he thought that the brain was really just like
- 7:44Speaker 4: a radiator, like a brain just there to like cool people. Yeah,
- 7:49Speaker 4: jes United has all these like lumps and wriggles like
- 7:51Speaker 4: that would make sense, right kind of.
- 7:53Speaker 2: Yeah, sure, maybe dissipute the heat like coils like coils in.
- 7:57Speaker 4: Area, Yeah, yeah, like increasing the surface area.
- 8:00Speaker 2: Uh.
- 8:00Speaker 4: And if you think about it, it kind of makes sense, right,
- 8:02Speaker 4: Like if you are designing a human being, Like, why
- 8:05Speaker 4: would you put the most important part on this little
- 8:09Speaker 4: like appendage sitting at the top, you know, exposed to
- 8:13Speaker 4: Yeah it's exposed. Yeah yeah what did you put it?
- 8:16Speaker 4: Like in the chest right protected by ribs and organs
- 8:20Speaker 4: Like that would make a little bit more sense. But no,
- 8:22Speaker 4: it's like it's sticking up in our hands. It's a
- 8:25Speaker 4: little peninsula on the box. Yeah yeah, so easy to
- 8:29Speaker 4: knock or or chop off. So he didn't quite have
- 8:33Speaker 4: it right, But people think that maybe the Egyptians knew
- 8:37Speaker 4: a little bit more about the brain. So there's this
- 8:39Speaker 4: famous papyrus papyrus scroll, yeah, that they found made by
- 8:47Speaker 4: the ancient Egyptians where they kind of like documented medical cases.
- 8:52Speaker 4: It's called the Edwin Smith Papyrus.
- 8:56Speaker 2: Yes, like the thought yeah.
- 9:02Speaker 4: Oh that's another brain game right there. So we know,
- 9:07Speaker 4: like the Addigus catalog all these medical things like oh,
- 9:09Speaker 4: if you break an arm, this is what happens. If
- 9:11Speaker 4: you sever your spinacle, this is what happened. And there's
- 9:13Speaker 4: like an entry number twenty in this squirrel that says,
- 9:17Speaker 4: you know, if you get hit in the head card,
- 9:19Speaker 4: we know that sometimes you can lose the ability to talk.
- 9:24Speaker 4: So like in their heads they're thinking, oh, your brain
- 9:28Speaker 4: is good for things like talking. So that's kind of
- 9:31Speaker 4: like the earliest we think kind of a record of
- 9:36Speaker 4: people humans kind of understanding what the brain is doing.
- 9:40Speaker 2: Oh wow.
- 9:41Speaker 1: And this this also reminds us clearly of a similar
- 9:49Speaker 1: practice indicative of recognizing the importance of the brain as
- 9:53Speaker 1: an organ, which is the practice of trepan nation, right. Uh,
- 10:00Speaker 1: trepanation being.
- 10:03Speaker 2: The demons.
- 10:04Speaker 1: Yeah yeah, yeah, yeah, venting relieving pleasure, yeah, drilling a
- 10:10Speaker 1: physical hole somewhere in the cranium. I think for a
- 10:16Speaker 1: lot of us lay for the primary amazing thing about
- 10:21Speaker 1: the practice of trapanation is that people survived somehow.
- 10:27Speaker 4: Yeah right, Yeah, it's wild. Basically, there's not much activity
- 10:31Speaker 4: going on like understanding the brain up until about the
- 10:35Speaker 4: eighteen hundreds, and that's when people really started to record
- 10:39Speaker 4: things like hey, if you open up your skull and
- 10:41Speaker 4: you dig a hole through here, this can happen. Or
- 10:44Speaker 4: if you open up this part of the brain and
- 10:45Speaker 4: you kind of like mess around with it or apply
- 10:48Speaker 4: electricity like that, your arm will move and so yeah,
- 10:53Speaker 4: so that's one of the things that people did in
- 10:55Speaker 4: the eighteen hundreds, which which opened up your brain and
- 10:58Speaker 4: pok it. And it's sort of dubious to us.
- 11:01Speaker 2: Now that's not to say.
- 11:04Speaker 3: Syram that gave us that information, but which is often
- 11:07Speaker 3: the case with early discovery, it's like, yeah, you know,
- 11:10Speaker 3: you gotta break a few eggs to make a science online.
- 11:14Speaker 4: Be a little bit of a mad scientist. Yeah, but
- 11:16Speaker 4: it taught us a lot, Like it started to kind
- 11:18Speaker 4: of piece everything together. People started to figure out, oh,
- 11:22Speaker 4: like the brain has parts. You know, it's not just
- 11:24Speaker 4: like one giant computer chip. It's got like a little
- 11:28Speaker 4: processor for this over here and a little processor for
- 11:30Speaker 4: that out over there, and so that's kind of how
- 11:31Speaker 4: it started, really kind of ramping up the history of
- 11:35Speaker 4: brain science.
- 11:36Speaker 1: Now we're talking the eighteen hundreds at this point, which
- 11:39Speaker 1: means from what Noel and I understand, this means this happens,
- 11:45Speaker 1: this great scientific inquiry occurs in the same sort of
- 11:51Speaker 1: historical milieu as a lot of quack science. Right, I
- 11:56Speaker 1: guess we should talk about phrenology a little bit.
- 11:59Speaker 4: Yeah, yeah, yeah, Well it's it's sort of a it's
- 12:02Speaker 4: a bit of a sketchy thing to delineate between quack
- 12:05Speaker 4: science and really thought right, you know what I mean.
- 12:07Speaker 4: Like back then, it's like it's like accusing a cavement
- 12:10Speaker 4: of not being good scientists. You know, they just didn't know,
- 12:13Speaker 4: and so they were just trying all these different theories.
- 12:15Speaker 4: They had all these ideas. They were going on vibes
- 12:18Speaker 4: basically vibes, and yeah, it's a Phrenology was a huge
- 12:24Speaker 4: deal in the eighteen hundreds. People thought that, you know,
- 12:27Speaker 4: there was this idea that the brain is mapped, like
- 12:29Speaker 4: there's areas that do different things. But so people would
- 12:32Speaker 4: just guess, like, oh, the part of the back part of
- 12:33Speaker 4: your rank, that's where that's where your love is located
- 12:36Speaker 4: and the front part is where your egoism is located,
- 12:40Speaker 4: and so they just if you look it up phrenology,
- 12:42Speaker 4: there's all these like maps. I think most people have
- 12:45Speaker 4: probably have probably seen them, just like a human head
- 12:47Speaker 4: with like areas kind of like a like a meat
- 12:50Speaker 4: diagram and a cow for one little.
- 12:53Speaker 2: Regions where the tenderline is exactly.
- 12:55Speaker 4: Yeah, yeah, yeah.
- 12:57Speaker 1: And that was informed, unfortunately by a lot of confirmation bias,
- 13:04Speaker 1: we could argue from Western Europe at the time, wherein
- 13:09Speaker 1: people would say, oh, we've made this rough Butcher's diagram
- 13:14Speaker 1: or topography of a cranium, and based on this bump,
- 13:19Speaker 1: this guy is going to be good at what's a
- 13:23Speaker 1: silly thing to be good at?
- 13:25Speaker 2: In the unicycle.
- 13:26Speaker 1: This guy's great at unicycles. Yeah, look at the other bump,
- 13:31Speaker 1: you know, right there by the temple. This is our
- 13:34Speaker 1: unicyclist juggler phrenology.
- 13:38Speaker 2: Jorge.
- 13:39Speaker 1: Was it widely accepted in its day.
- 13:41Speaker 4: I think it was, you know, as accepted as like
- 13:45Speaker 4: you know, somebody selling tonics, you know, going from town
- 13:49Speaker 4: to town in the Old West selling tonics to rejuvenate
- 13:52Speaker 4: your vigor or something like that. You know, it's something
- 13:55Speaker 4: that people weren't quite sure it was true or not,
- 13:57Speaker 4: and some people claim that they were starting up it
- 14:00Speaker 4: and you know, people rolled the dice.
- 14:03Speaker 3: Not a far jump from things like the humors, you know,
- 14:06Speaker 3: the idea of leeching and blood letting in order to
- 14:09Speaker 3: balance out these supposed you know, materials within the body.
- 14:14Speaker 3: And then honestly, I'm not trying to poop anybody's beliefs here,
- 14:17Speaker 3: but not too too far off from things like chakras
- 14:20Speaker 3: and meridian lines in some you know, Eastern medicine that
- 14:24Speaker 3: some people think is quackery and some people swear by.
- 14:26Speaker 3: So I mean, it's just interesting the way some of
- 14:28Speaker 3: that stuff is still around and believed in or not
- 14:31Speaker 3: believed in depending.
- 14:32Speaker 4: No, no, that stuff is quackery.
- 14:34Speaker 2: No okay, Oh the.
- 14:37Speaker 1: Professor came out on that one.
- 14:40Speaker 4: No fense to the Crystal fans.
- 14:42Speaker 2: Yes, yes, yes, we just being diplomatic.
- 14:45Speaker 1: We are being diplomatic, and we we share the same pursuits,
- 14:49Speaker 1: which is always going to be hopefully the collective, objective
- 14:55Speaker 1: interrogation of the world around us and within us. One
- 15:06Speaker 1: thing we were talking about a little bit off air.
- 15:11Speaker 1: It pertained to some some just phenomenal and again, as
- 15:18Speaker 1: you said Jorge. Ethically, dubious learnings that came. You mentioned
- 15:24Speaker 1: the earlier realization from humanity that certain parts of the
- 15:30Speaker 1: brain function in certain ways right and excel in certain things.
- 15:35Speaker 1: And at the end of our first conversation we introduced
- 15:41Speaker 1: a patient who for a long time was simply known
- 15:44Speaker 1: as HM, and HM, as we find, is pivotal to neuroscience,
- 15:52Speaker 1: perhaps because of well, gosh, can we tell can we
- 15:57Speaker 1: tell the story? Yes, super fasting story. This was a
- 16:02Speaker 1: little bit later. This was in the nineteen thirties that
- 16:05Speaker 1: this man came about. His name was Henry Malaysan, but
- 16:09Speaker 1: for a long time people didn't know his name because
- 16:11Speaker 1: when you become a medical subject, they kind of make
- 16:14Speaker 1: you anonymous. So for a long time, for many years,
- 16:16Speaker 1: he was just known as patient AHM. And so this
- 16:20Speaker 1: was a guy who had a lot of seizures as
- 16:23Speaker 1: a kid. Some people think it maybe happened after he
- 16:26Speaker 1: had like a bike accident and then he knocked his head.
- 16:28Speaker 1: Some people think he was just kind of he just
- 16:30Speaker 1: had these seizures for no reason. So it's not quite
- 16:32Speaker 1: clear how or why he got these features, but they
- 16:34Speaker 1: were like super intense, like he couldn't really function it
- 16:38Speaker 1: would really kind of make him not able to have
- 16:42Speaker 1: a job or go to school or things like that.
- 16:44Speaker 4: And at the time, as you said, the doctors were like, oh,
- 16:47Speaker 4: I know how to cure it this. I'll just poke
- 16:49Speaker 4: a hole in your head and mess around with it.
- 16:51Speaker 4: And so a common procedure back then was basically a lobotomy,
- 16:57Speaker 4: Like they would just kind of stick this long needle
- 17:02Speaker 4: kind of through your eye socket, did you like move
- 17:04Speaker 4: your eye a little bit out of the way, and
- 17:06Speaker 4: then you stick it in there and then kind of
- 17:08Speaker 4: mess around. And what they did for him specifically was
- 17:12Speaker 4: they destroyed most of his hippocampus, so like deep inside
- 17:17Speaker 4: your brain you have this little these little lumps called
- 17:19Speaker 4: the hippocampus. And you know, his seizures were so severe
- 17:24Speaker 4: that this doctor called Williams Coville thought that he needed
- 17:29Speaker 4: to take out both his hippocampus, and so he did.
- 17:32Speaker 4: And the amazing thing is it sort of worked, like
- 17:35Speaker 4: his seizure stopped. But unfortunately it had a bad side effect,
- 17:40Speaker 4: which is that Henry Molaysan was not able to make
- 17:44Speaker 4: new memories. So like he remembered his whole life, his childhood,
- 17:49Speaker 4: you know, his early adulthood, right up until the day
- 17:52Speaker 4: he had his surgery. But after that he couldn't remember
- 17:56Speaker 4: more than thirty minutes at a time.
- 17:58Speaker 1: He couldn't encode information.
- 18:02Speaker 4: Right, Like if you met him and you said hey,
- 18:03Speaker 4: and he like, he could tell you where he grew up,
- 18:06Speaker 4: who his mother was, and everything, but thirty minutes later
- 18:09Speaker 4: he would totally forget he met you, Or thirty minutes later,
- 18:12Speaker 4: he couldn't tell you how he got to where he was,
- 18:15Speaker 4: what he had for breakfast, you know, any he couldn't
- 18:18Speaker 4: tell you anything beyond thirty minutes ago.
- 18:20Speaker 1: Okay, well, we've all met executive producers and before you see.
- 18:26Speaker 4: A botimized Oh.
- 18:29Speaker 1: So this this is a moment of tremendous significance to
- 18:37Speaker 1: the history of neuroscience when and first off, him's existence
- 18:43Speaker 1: at this point is cursed. You mentioned earlier that this
- 18:48Speaker 1: was this was a primary source for the film Momento.
- 18:55Speaker 2: Is that correct?
- 18:56Speaker 4: Yeah, the Christopher Nolan film The When He Got kind
- 18:59Speaker 4: Of I got famous for initially Memento. It was this
- 19:03Speaker 4: guy who basically lived this life, but in our modern
- 19:06Speaker 4: world right now and so he couldn't remember more than
- 19:09Speaker 4: thirty minutes ago, and so and so that movie's kind
- 19:12Speaker 4: of told backwards in time. It's like he's you're sort
- 19:15Speaker 4: of living the movie like he is living in It's like, oh,
- 19:17Speaker 4: I'm here, Why am I here? I don't know why
- 19:19Speaker 4: I'm here? And then you flash back to like thirty
- 19:21Speaker 4: minutes ago to figure out how he got there, and
- 19:24Speaker 4: then you keep flashing back thirty minutes at a time.
- 19:26Speaker 4: That's the movie. And this guy like actually lifted. He
- 19:31Speaker 4: just woke up every day and thirty minutes the world
- 19:34Speaker 4: was brand new to him.
- 19:35Speaker 2: That's a good yeah.
- 19:36Speaker 3: Yeah, And I don't know if that's like terrifying or
- 19:38Speaker 3: kind of awesome, but now I think it's terrifying.
- 19:40Speaker 2: I don't think it would a good way to experience
- 19:42Speaker 2: the world.
- 19:43Speaker 4: Well, it wouldn't make you useful for pretty much anything
- 19:46Speaker 4: except subject There's.
- 19:48Speaker 3: There's something to be said about, like, you know, if
- 19:50Speaker 3: we could just wipe our memories or do a little reset.
- 19:54Speaker 2: But no, I'm sorry not making life.
- 19:56Speaker 3: This is a very very serious condition, but one that
- 19:59Speaker 3: shut up lot of light on some things that didn't
- 20:02Speaker 3: require people to go necessarily digging around in people's brains, right.
- 20:06Speaker 4: Right, right, yeah. In particularly, she had a lot of
- 20:08Speaker 4: light on how memory works in our brain, so, like
- 20:11Speaker 4: before this patient, mostly people thought that memory was something
- 20:15Speaker 4: that was spread across your brain, Like people thought your
- 20:19Speaker 4: brain was used to giant kind of a computer ship
- 20:21Speaker 4: and you had just like you know, you store memories
- 20:23Speaker 4: in a little bit here, a little bit there, a
- 20:25Speaker 4: little bit everywhere. It's just kind of like evenly spread out.
- 20:29Speaker 4: But what was fascinating about patient HM is that he
- 20:32Speaker 4: could remember his childhood, his early adulthood. He couldn't make
- 20:35Speaker 4: me memories, but you could teach him motor skills like
- 20:39Speaker 4: he could. Yeah, Like you could teach him how to
- 20:42Speaker 4: play tennis, and the first day he would be terrible
- 20:46Speaker 4: at it, but if he kept practicing, he would get
- 20:48Speaker 4: better at it, but he wouldn't remember having practice.
- 20:52Speaker 2: Wow.
- 20:52Speaker 1: So every time this guy, for example, plays tennis, he's
- 20:57Speaker 1: just a little bit better, right, but he doesn't know why.
- 21:01Speaker 2: He's just really good at it.
- 21:04Speaker 4: Yeah, Like you know, by session thirty, I imagine, right,
- 21:08Speaker 4: this is hypothetically because I don't think they really has
- 21:11Speaker 4: them to play tennis, But like by session thirty, he'd
- 21:13Speaker 4: be like, you know, hitting aces and returning loves and
- 21:16Speaker 4: he'd be like, oh my god, I had no idea
- 21:18Speaker 4: I could play tennis. That was basically his experience.
- 21:21Speaker 1: I hope he has a I hope he has a
- 21:25Speaker 1: lived perception that he is a virtuoso. You know what
- 21:30Speaker 1: I mean, because it's always the first thirty minutes that
- 21:33Speaker 1: he's played tennis.
- 21:34Speaker 4: Yeah, right right, But then in the next session if
- 21:36Speaker 4: he doesn't play tennis, he has no idea he's good
- 21:38Speaker 4: to play tennis.
- 21:39Speaker 1: Al true periodic victory.
- 21:41Speaker 2: Yeah, real conundrum.
- 21:42Speaker 3: So what did this teach us though about the brain?
- 21:45Speaker 3: That there are certain things that could not be recalled,
- 21:49Speaker 3: but yet certain things had a bit more of a
- 21:52Speaker 3: sense memory perhaps.
- 21:54Speaker 4: Yeah. Mainly what it taught people is that there are
- 21:56Speaker 4: different kinds of memory. Like I think most people who
- 21:59Speaker 4: are listening to about short term memory long term memory.
- 22:02Speaker 4: So those are two separate things in your brain. But
- 22:05Speaker 4: for a long time, we didn't know that, and we
- 22:07Speaker 4: didn't know there was such a thing as motor memory.
- 22:09Speaker 4: Like when you like your signature, you can do you
- 22:12Speaker 4: write your signature without thinking about it. It's just in
- 22:14Speaker 4: your muscle memory. Or some people can play the piano
- 22:16Speaker 4: with is your muscle memory. So that's in a different
- 22:19Speaker 4: part of your brain than the long term. The short
- 22:21Speaker 4: term even your verbal and language all that is just
- 22:25Speaker 4: in separate areas. It's still in areas, but it's a
- 22:29Speaker 4: little bit more spread out of the brain. And so
- 22:30Speaker 4: that's kind of what it unlocked for scientists is like,
- 22:33Speaker 4: oh wait, memory is not just this like one hard drive.
- 22:36Speaker 4: It's like a whole bunch of little hard drive and
- 22:38Speaker 4: a whole bunch of different ways that memories gets stored.
- 22:42Speaker 1: So that teaches us as well about that reminds us
- 22:46Speaker 1: of things like what is it called broksophasia or something?
- 22:50Speaker 1: So patient HM was capable of retaining and speaking the
- 22:55Speaker 1: language she had learned in his childhood. What we're talking about,
- 23:00Speaker 1: we talk about brocos of phasia is of course the
- 23:02Speaker 1: breakdown of as you said, Jorge, a different version of
- 23:06Speaker 1: the hard drive, right, the one that controls linguistic aptitude.
- 23:11Speaker 1: Did he I don't know the answer. I'm asking honestly,
- 23:17Speaker 1: did sense memory impact anything?
- 23:20Speaker 2: Like?
- 23:21Speaker 1: Could he the same way he was hypothetically taught to
- 23:24Speaker 1: be good at tennis? Could he be taught to and
- 23:27Speaker 1: we're breaking tons of ethical experimentation laws on this, but
- 23:33Speaker 1: could you possibly teach this patient to be avoidant of
- 23:40Speaker 1: or attracted to, say, a certain stimuli like a smell
- 23:45Speaker 1: and then wait for that reset in the brain function.
- 23:50Speaker 1: You know, is this guy? Is it possible to make
- 23:53Speaker 1: a world where this guy is waking up experiencing lucidity
- 23:58Speaker 1: every thirty minutes and now he just hates the No,
- 24:02Speaker 1: what's a good smell to hate? Oh, my gosh, the
- 24:05Speaker 1: smell of coffee, like coffee, coffee, coffee is a great one.
- 24:09Speaker 1: Is it possible to uh, would it be possible to
- 24:13Speaker 1: teach sense memory in an olfactory way or what does
- 24:18Speaker 1: that take? Right?
- 24:20Speaker 4: I think the idea is that he couldn't make long
- 24:23Speaker 4: term memories, so and I'm not sure that like our
- 24:27Speaker 4: associations with certain smells, I'm not sure quite sure where
- 24:31Speaker 4: that is in the brain. So it might some of
- 24:33Speaker 4: it might be in our long term memory, in which
- 24:35Speaker 4: case he couldn't. You couldn't train that in him. But
- 24:38Speaker 4: some of it might be automatic, in which case you
- 24:42Speaker 4: probably could.
- 24:42Speaker 2: Yeah.
- 24:43Speaker 1: That is fascinating, and it occurs in step with we
- 24:50Speaker 1: wanted to ask you about this with another pivotal moment
- 24:54Speaker 1: in neuroscience understanding and and folks, by the way, I
- 24:58Speaker 1: feel like we've been very very clear about this. Do
- 25:02Speaker 1: not try this at home, no matter how mad you
- 25:06Speaker 1: are at your sibling. Do not try this at home.
- 25:10Speaker 2: Right.
- 25:11Speaker 1: There is another case that occurred in the eighteen hundreds,
- 25:17Speaker 1: so a little bit prior to HM, the infamous Phineas Gauge.
- 25:23Speaker 2: Yes, yeah, railroad tie.
- 25:25Speaker 1: Yeah yeah.
- 25:26Speaker 4: So Finished Gage was a railroad worker. He's just a
- 25:29Speaker 4: regular dude in eighteen mid eighteen hundreds up there in Vermont,
- 25:36Speaker 4: and you know, by all accounts, he was a nice guy,
- 25:39Speaker 4: you know, lived his life, worked hard. One day, he
- 25:42Speaker 4: was like installing these long metal rods on a rock
- 25:46Speaker 4: to make way for like a railroad. And what they
- 25:49Speaker 4: do is they pack some dynamite in there, they stick
- 25:53Speaker 4: the rod, and then they light the fuse and then
- 25:54Speaker 4: that blows up the rock. What could go wrong? Right,
- 26:00Speaker 4: thing exploded on him and this meter long iron rod
- 26:04Speaker 4: basically went through his head. So he kind of went
- 26:08Speaker 4: in through his left cheek, kind of up and above,
- 26:12Speaker 4: kind of behind his eyeballs, through the front part of
- 26:16Speaker 4: his brain, and then it came out the top. Gar
- 26:24Speaker 4: He did not. He survived, that is the fascinating thing.
- 26:28Speaker 4: And so he got better and everyone's like, oh, oh
- 26:31Speaker 4: my god, that's amazing. He's a miracle. I guess the
- 26:35Speaker 4: brain is not that important. For take away. Yeah, for
- 26:40Speaker 4: a long time, he was basically used as an example
- 26:43Speaker 4: of like, oh, the brain is like, you know, just
- 26:45Speaker 4: one big amorsive most mass, and if you lose a
- 26:48Speaker 4: little bit, it's like, you know, you lose a little bit,
- 26:50Speaker 4: but whatever, your brain has the risk of itself to
- 26:53Speaker 4: like make you who you are. And so he's revived.
- 26:56Speaker 4: People thought he was fine, but literally little people sort
- 26:59Speaker 4: of realized there was something a little off about him,
- 27:03Speaker 4: like he quite wasn't quite himself like he reportedly, he
- 27:07Speaker 4: just had like a he kind of basically became an
- 27:10Speaker 4: a hole.
- 27:10Speaker 2: I don't know if I can say that.
- 27:13Speaker 1: Yeah, he had a he had a market change in
- 27:16Speaker 1: his temperance, right he was he was now seen as yeah,
- 27:22Speaker 1: like you said, a whole and thank you for keeping
- 27:25Speaker 1: it a family show.
- 27:27Speaker 4: But he was not a nice guy. Not a nice guy.
- 27:29Speaker 2: Oh by all accounts.
- 27:30Speaker 3: Before that though, he was a perfectly nice fellow, a
- 27:33Speaker 3: hard worker, like you said, and in fun and fine
- 27:35Speaker 3: to be around, jovial. And then after this people started
- 27:38Speaker 3: noticing that something in his personality had shifted.
- 27:42Speaker 4: You know, Yeah, his personality had shifted from being like
- 27:45Speaker 4: a nice guy to like being very ill tempered, like
- 27:47Speaker 4: he just grumpy all the time. But and then beyond
- 27:50Speaker 4: his personality, he also kind of had a little bit
- 27:53Speaker 4: of ADHD now, like he could he find it hard
- 27:56Speaker 4: to focus, He couldn't really concentrate, and so he's just
- 27:58Speaker 4: he was just kind of like a frustrated person all
- 28:01Speaker 4: the time. And you know, people who knew me were like,
- 28:04Speaker 4: this is not the same person. And so only later
- 28:08Speaker 4: when the people realize, like, oh, this is perfectly explained
- 28:11Speaker 4: because the front part of your brain, that's kind of
- 28:14Speaker 4: where your personality is and where your ability to focus is.
- 28:19Speaker 4: So that was another big part of kind of like
- 28:21Speaker 4: mapping the brain and figuring out that there are parts
- 28:24Speaker 4: to it that do different things and which parts do
- 28:26Speaker 4: different things.
- 28:27Speaker 3: I gotta say, there's a really great episode of our
- 28:30Speaker 3: sister podcast, Stuff You Missed in History Class, all about
- 28:34Speaker 3: Phineas Gage back in the Archives. I remember back when
- 28:37Speaker 3: I produced that show, that was the first time I'd
- 28:39Speaker 3: heard of him, and I thought it was super fascinating.
- 28:41Speaker 3: So do check that one out for a deep dive
- 28:43Speaker 3: on this fascinating character.
- 28:45Speaker 1: Also fascinating to borrow that word there. It's also fascinating
- 28:51Speaker 1: that his treating physician was a guy named jam Horlow
- 28:59Speaker 1: and jam Harlow, like many Western physicians of his day,
- 29:05Speaker 1: held in abiding interest in phrenology. So maybe if you are,
- 29:12Speaker 1: if you are a boffin or a doctor of the day,
- 29:15Speaker 1: maybe it's not the fact that this meter long rod
- 29:19Speaker 1: went through the front part of this human brain, it's
- 29:22Speaker 1: that it altered the shape of the cranium. So now
- 29:25Speaker 1: he doesn't have good guy bumps.
- 29:29Speaker 4: Well, what's interesting is that, you know, this idea sounds crazy, right,
- 29:33Speaker 4: like you could judge how a brain works by how
- 29:36Speaker 4: well brain is good at something by its shape. But
- 29:39Speaker 4: that's actually something they found kind of in the nineties
- 29:42Speaker 4: early two thousands, was that they looked at brain scans
- 29:45Speaker 4: of taxi drivers in London.
- 29:48Speaker 2: The knowledge, yeah, the knowledge of this, the way it
- 29:52Speaker 2: sort of changed the pathways, right.
- 29:55Speaker 4: Yeah, yeah, So they studied the brains of taxi drivers
- 29:59Speaker 4: in life then, and they talk about the knowledge, right, like,
- 30:02Speaker 4: you know, if you're brand new at driving a taxi
- 30:04Speaker 4: in London, you're clueless. You have no idea where anything
- 30:06Speaker 4: is if you've ever been there, there's like alleys everywhere
- 30:09Speaker 4: with all these it's impossible to navigate. But once you've
- 30:12Speaker 4: done it for a while you know, the whole day
- 30:14Speaker 4: of the land, you can take anyone anywhere. They studied
- 30:17Speaker 4: the brains of these people, and they found that people
- 30:19Speaker 4: who've been doing it for a long time, that part
- 30:21Speaker 4: of your brain that stores like locations and spatial memory
- 30:27Speaker 4: that's actually bigger, like it grows.
- 30:30Speaker 2: The mind is shriveled. Y'all. I'm so bad at directions.
- 30:34Speaker 2: I have no sense of geography.
- 30:36Speaker 3: It's really bad because yeah, because maybe it was, it's
- 30:41Speaker 3: been bad even since before, you know what. It's just
- 30:44Speaker 3: funny though, I will say this, I have recently been
- 30:47Speaker 3: trying to actively not use maps, and I have found
- 30:52Speaker 3: that it improves my sense of direction overall.
- 30:56Speaker 2: So I think it can be almost relearned or you know, improved. DuPont.
- 31:00Speaker 5: Yeah.
- 31:01Speaker 2: Yeah.
- 31:01Speaker 4: My wife just talked to a coworker who said he's
- 31:05Speaker 4: taking his son out for walks just to teach him
- 31:08Speaker 4: how to go on walks.
- 31:09Speaker 2: Yeah. Yeah, he's and it's not always inherent, you know, Yeah.
- 31:15Speaker 4: Because he's going out to college and you know, kids
- 31:17Speaker 4: do they basically maybe don't have that ability to walk around.
- 31:22Speaker 1: Yeah. I haven't had to uh be lost in the woods,
- 31:25Speaker 1: right like our four bears. Uh Yeah, It's funny. It's
- 31:29Speaker 1: funny you say that because we we've talked in the
- 31:33Speaker 1: past about these arguments regarding you know, regarding the advent
- 31:40Speaker 1: of offloading uh, some sort of process right from the
- 31:44Speaker 1: human machine to an external machine. And I love that
- 31:49Speaker 1: you're bringing up the knowledge because that was a revolutionary
- 31:54Speaker 1: study in neuroscience. It reminds me as well of a
- 31:59Speaker 1: study I want to say it was in Why You
- 32:04Speaker 1: in two thousand and eight, admittedly small sample size, but
- 32:09Speaker 1: they studied people who meditate, Buddhist monks in particular, and
- 32:14Speaker 1: they found something similar similar to the similar to how
- 32:21Speaker 1: the use of the part of the brain that is
- 32:24Speaker 1: occupied with spatial positioning appropreception. You could argue, similar to
- 32:31Speaker 1: how their continued practice of knowing where they are and
- 32:36Speaker 1: where they're going literally became mind over matter and increased
- 32:42Speaker 1: the I believe the argument is not just the increase
- 32:46Speaker 1: in size, but the increase in density of synaptic connections.
- 32:52Speaker 1: The study in eight with Buddhist monks found, and I'm
- 32:59Speaker 1: going to sound so pops, I hear, and I apologize,
- 33:02Speaker 1: it found that the part of the brain position toward
- 33:08Speaker 1: or associated with things like empathy and compassion was actually
- 33:13Speaker 1: denser and larger and exhibited more activity in those Buddhist
- 33:19Speaker 1: monks versus a sample size of you know, jerks like.
- 33:25Speaker 4: Us, non Buddhist monks, not.
- 33:37Speaker 1: Enlightened, not yes, not enlightened, perfect diplomacy. So this brings
- 33:42Speaker 1: us to I think I think the general umbrella term
- 33:46Speaker 1: for this concept is neuroplasticity. Is that what we're kind
- 33:50Speaker 1: of talking about? What is neuroplasticity.
- 33:53Speaker 4: Yeah, it's kind of this idea that your brain is
- 33:56Speaker 4: not static, like at all, Like your brain is constantly
- 34:00Speaker 4: kind of rewiring itself, kind of constantly tuning itself. And
- 34:05Speaker 4: it's not like you're necessarily growing new neurons, but these
- 34:09Speaker 4: neurons are making new connections between themselves. And also kind
- 34:14Speaker 4: of more importantly is that these the connections that they have,
- 34:18Speaker 4: they're constantly kind of recalibrating themselves. And actually that's kind
- 34:22Speaker 4: of what's happening. That's how like ais learn. You know,
- 34:25Speaker 4: if you look at these neural net models, basically what
- 34:29Speaker 4: they're changing when they're learning stuff is the weighing of
- 34:37Speaker 4: the synaptic connections. So like how strong priority wise or
- 34:42Speaker 4: yeah kind of priority wise. Yeah, Like each neurons is
- 34:45Speaker 4: connected to like let's say a hundred other neurons, and
- 34:48Speaker 4: like it's getting all these inputs, so which ones do
- 34:51Speaker 4: you ignore? Which ones do you listen to? And so
- 34:54Speaker 4: that happens at what are called synapses, which is kind
- 34:57Speaker 4: of where like you know, the little branches of two
- 34:59Speaker 4: neurons kind of mean.
- 35:00Speaker 2: And firing, right, firing synapses.
- 35:04Speaker 4: Firing, yeah, firing synapses where that gets transmitted from one
- 35:07Speaker 4: to the other. So that's that's where that's happening.
- 35:10Speaker 3: Yeah, And when you look at a brain scan or
- 35:12Speaker 3: an MRI, if I'm not mistaken, you can literally see
- 35:16Speaker 3: this activity right lighting up in different regions of the brain.
- 35:20Speaker 4: Kind of these these are like almost like molecule size.
- 35:23Speaker 4: They're like super super tiny, so you can't see them
- 35:25Speaker 4: like an MRI, but you can see kind of like
- 35:27Speaker 4: when you're looking at MRI, what you're looking at is
- 35:29Speaker 4: like the oxygen consumption of your neurons. So you can
- 35:32Speaker 4: tell like, oh, these neurons are being active because they're God, drinking.
- 35:35Speaker 2: Up a lot makes a lot of sense. So it's
- 35:37Speaker 2: an indicator, got it. Yeah, Yeah, that's fascinating.
- 35:40Speaker 1: So now we have learned that in given that the
- 35:47Speaker 1: universe observable according to Big Bang theory is about fourteen
- 35:52Speaker 1: billion years old. Humans are real up and coming fad overall.
- 35:58Speaker 4: Right, we're the latest it beings. Yeah we are, We
- 36:03Speaker 4: sure are, and for long. That's how fads work.
- 36:08Speaker 1: And and we we also learned in that very brief
- 36:12Speaker 1: span of time that we call humanity. Uh, people went
- 36:17Speaker 1: from totally thinking the soul was in the most protected
- 36:22Speaker 1: part of the body, the torso right to figuring out, oh,
- 36:26Speaker 1: that fatty thing in your head does something. Right after
- 36:30Speaker 1: we figured out just how to stop eating each other's brains. Uh,
- 36:34Speaker 1: just gonna throw that in there, and and and then
- 36:38Speaker 1: from there we see this, this vast series of at
- 36:45Speaker 1: times problematic innovations, sometimes based in accident, sometimes based in
- 36:52Speaker 1: confirmation bias or as you said, quack science of phrenology
- 36:57Speaker 1: or hate. Where does the exploration of consciousness and neuroscience
- 37:03Speaker 1: go in the future, By the way, just going to
- 37:06Speaker 1: put this out there for posterity. Jorge, Noel Max and
- 37:10Speaker 1: I are recording this on Monday, June twenty third, twenty
- 37:14Speaker 1: twenty five, So no pressure, Orge. Next thousand years, where
- 37:18Speaker 1: are we at.
- 37:21Speaker 4: No set, assuming we survived the next I don't know months,
- 37:25Speaker 4: Oh my god, existence here you know. I think these
- 37:29Speaker 4: things are like Pandora's blogs. You know, once you open them,
- 37:32Speaker 4: you can't go back, you know. And so I think
- 37:36Speaker 4: we're going to be understanding the universe a lot more,
- 37:41Speaker 4: We're going to be understanding things at the quantum level
- 37:43Speaker 4: a lot more. And who knows what's going to happen
- 37:48Speaker 4: with AIS. You know, it's quite I think possible that
- 37:52Speaker 4: within I don't know, twenty years, there'll be a conscious
- 37:56Speaker 4: AI who is smarter than us.
- 37:59Speaker 3: I think can That is the term that gets thrown
- 38:01Speaker 3: around a lot, is singularity in terms of AI. But
- 38:03Speaker 3: then we also in talking about the Big Bang that's
- 38:05Speaker 3: referred to as a singularity event, and maybe the terms
- 38:08Speaker 3: are sort of used loosely, But can you kind of
- 38:11Speaker 3: talk about that term and how it applies to both
- 38:13Speaker 3: of those different things. Is it really just kind of
- 38:15Speaker 3: like an it moment where a big thing happens.
- 38:18Speaker 2: Yeah.
- 38:19Speaker 4: So consciousness is one of the most debated things in
- 38:23Speaker 4: like neuroscience psychology. Like if you ask any scientist like
- 38:26Speaker 4: what is even consciousness? You'll get one hundred different answers.
- 38:30Speaker 4: Some people think it's like totally kind of biologically based,
- 38:35Speaker 4: like it's you know, a dog can have some kind
- 38:38Speaker 4: of consciousness and can have a little bit of a consciousness,
- 38:41Speaker 4: you know, machine can have a consciousness the material materialist philosophy. Yeah, yeah, exactly.
- 38:49Speaker 4: And some people think there's something kind of special and
- 38:53Speaker 4: almost supernatural about it, you know, even scientists sometimes think
- 38:57Speaker 4: that when it happens, it's like this kind of indescribable
- 39:03Speaker 4: thing that happens.
- 39:04Speaker 1: Yeah, Promethean lighting in a bottle. Yeah, And this is
- 39:10Speaker 1: where we get to the vast precipice, some would say,
- 39:18Speaker 1: or the vast horizon, depends upon your interpretations of as
- 39:23Speaker 1: you said, Nol, singularity or transhumanism and future futurism. Nolan
- 39:30Speaker 1: and I were talking off air or at length about
- 39:34Speaker 1: the concept of AI, artificial intelligence large language models. We
- 39:41Speaker 1: touched on it naturally a little bit in part one,
- 39:44Speaker 1: but perhaps we close out chapter two of our conversation
- 39:49Speaker 1: on the history of brain science by exploring the nature
- 39:55Speaker 1: of AI just a bit further. Now you have you have,
- 40:00Speaker 1: through your work explore human human computer interaction in depth,
- 40:08Speaker 1: right and yeah, and so where do you see the
- 40:15Speaker 1: future of human interaction with AI going? You already said,
- 40:21Speaker 1: you know, there is a horizon where this kind of
- 40:24Speaker 1: thing exists. What will that tell us about the human brain? Oh,
- 40:28Speaker 1: my goodness, small dog. Well, it kind of depends on
- 40:34Speaker 1: where you land about how special the human brain is.
- 40:37Speaker 1: You know, like I personally am an engineer by training,
- 40:41Speaker 1: and to me, brains are really just like meat machines.
- 40:44Speaker 1: You know, It's like it's mechanical, there's chemicals, involves some
- 40:49Speaker 1: people think like quantum physics and quantum and certainly plays
- 40:53Speaker 1: a role in like those little tiny synapsis that we have,
- 40:56Speaker 1: in which case, you know, there is maybe some magic
- 40:59Speaker 1: to how the human rain works.
- 41:00Speaker 2: I think we're all made of star stuff.
- 41:04Speaker 1: Well, if the Big Bang is true, then technically that
- 41:07Speaker 1: that's also true, right.
- 41:08Speaker 3: Well yeah, we arose from something like that, right, and
- 41:11Speaker 3: we had to have.
- 41:12Speaker 4: Yeah yeah, well most of our the atoms and our
- 41:14Speaker 4: bodies were made inside of a star. Yeah, because the
- 41:18Speaker 4: universe at the beginning was just all hydrogen, and so
- 41:21Speaker 4: anything other than hydrogen was basically made by a star
- 41:25Speaker 4: and usually starts dying.
- 41:26Speaker 1: So yeah, this podcast brought to you by hydrogen. So
- 41:33Speaker 1: we're saying then that the nature of consciousness is still
- 41:39Speaker 1: something that the world's smartest people past, present, and possibly
- 41:45Speaker 1: future have debate, have debated, right, the materialist view of
- 41:51Speaker 1: this one thing in this one case, these physical processes,
- 41:57Speaker 1: these mechanics, and these chemical interactions, and then there's the
- 42:01Speaker 1: larger question is there something bigger? Right? Is an individual
- 42:07Speaker 1: consciousness only a node for a larger system which gets
- 42:12Speaker 1: little It's a lot of my old professors hate that idea.
- 42:19Speaker 4: Yeah, it's this idea like humans are the way that
- 42:22Speaker 4: the universe understands itself kind of. Is that what you're
- 42:25Speaker 4: talking about a little bit, Yeah.
- 42:27Speaker 1: Because you're talking about we're talking about now what we
- 42:30Speaker 1: would call Homo sapiens exceptionalism, right, yeah, right, the idea
- 42:37Speaker 1: that although one can observe perhaps emotions in a pet,
- 42:46Speaker 1: or what seems to be emotions in a pet, even
- 42:50Speaker 1: on the strength of various cognitive diagnostics, you could observe
- 42:55Speaker 1: maybe the way an octopus dreams, or the the functions
- 43:01Speaker 1: of certain higher order mammals.
- 43:03Speaker 3: To take what we're talking about metacognition here, right, like
- 43:06Speaker 3: the fact that humans are uniquely built to think about thinking,
- 43:10Speaker 3: to analyze themselves, sometimes into oblivion, which is why maybe
- 43:15Speaker 3: sometimes I'm jealous of the guy that can't remember anything
- 43:18Speaker 3: for more than thirty minutes, because it can be a
- 43:21Speaker 3: awaking nightmare at times what we do to ourselves in
- 43:25Speaker 3: terms of like thinking about thinking and all of the possibilities,
- 43:28Speaker 3: and it can be really exhausting, right.
- 43:31Speaker 4: Yeah, yeah, And they're fascinating cases in the history of
- 43:34Speaker 4: brain science to the kind of speak to consciousness. So
- 43:37Speaker 4: one fascinating case that is pretty recent are conjoined twins.
- 43:42Speaker 4: So there's a pair of famous twins called the Hogan twins,
- 43:47Speaker 4: and these are two girls who were born conjoined were
- 43:50Speaker 4: they basically share a brain, or they share parts of
- 43:53Speaker 4: the brain, and specifically they share like this part called
- 43:56Speaker 4: the thalamus, which is kind of like a kind of
- 43:58Speaker 4: a hub inside of your brain kind of relays information
- 44:01Speaker 4: and so it's too definitely to people, like you can
- 44:04Speaker 4: talk to one of them, you can talk to the
- 44:05Speaker 4: other of them. But they sort of share their consciousness
- 44:09Speaker 4: almost in a way like like one of them can
- 44:13Speaker 4: sense what when the other person. Sometimes one of them
- 44:21Speaker 4: can sort of sense what the other person is thinking,
- 44:24Speaker 4: and they can sort of each control different parts of
- 44:26Speaker 4: the other person's body kind of like one of them
- 44:29Speaker 4: controls the left leg of the other one, the other
- 44:32Speaker 4: one controls the right arm of the other one. I
- 44:35Speaker 4: forget the exact details, but it's kind of like, like
- 44:37Speaker 4: you said, kind of like we sometimes think being conscious
- 44:42Speaker 4: the only way to be conscious is to be conscious
- 44:44Speaker 4: like humans are right now, But there are other ways
- 44:46Speaker 4: that we can be conscious.
- 44:48Speaker 3: Well, I mean, even other non conjoined twin studies yield
- 44:50Speaker 3: some pretty interesting results, like in terms of potentially some
- 44:55Speaker 3: kind of link, you know, where there's at the very
- 44:58Speaker 3: least a what's the word I'm looking for, a kind
- 45:01Speaker 3: of intuition, you know, in terms of like that would
- 45:04Speaker 3: you know, surpass normal intuition maybe between regular siblings. I've
- 45:08Speaker 3: met known in my life multiple sets of identical twins,
- 45:12Speaker 3: and there's something to it.
- 45:13Speaker 2: It's very fascinating.
- 45:14Speaker 3: I would say that is a different kind of consciousness
- 45:16Speaker 3: in some ways where you are. Maybe it's a product
- 45:19Speaker 3: of sharing the same space so much and you know,
- 45:22Speaker 3: spending so much time around each other. But I have
- 45:24Speaker 3: seen something, some things that have a hard time explaining
- 45:27Speaker 3: in terms of the way twins can kind of know
- 45:30Speaker 3: what each other are thinking and feeling.
- 45:32Speaker 4: Yeah, I mean, there's definitely a role for intuition there,
- 45:35Speaker 4: and you know, it doesn't have to be physical consciousness,
- 45:37Speaker 4: Like you know, I kind of personally think that we
- 45:40Speaker 4: all kind of share as a human species some sort
- 45:42Speaker 4: of consciousness.
- 45:43Speaker 1: You know, through the collect it's unconscious, Yeah, like the
- 45:46Speaker 1: young and super consciousness, right right, Like that just.
- 45:51Speaker 2: Adds to that. You're right.
- 45:52Speaker 3: I'm sorry I didn't interrupt, but that's a really good point.
- 45:54Speaker 3: The Internet is, in and of itself, a super scaled
- 45:59Speaker 3: version of that just contributes to what we're talking about.
- 46:02Speaker 4: Yeah, it just really all depends on how you define
- 46:05Speaker 4: this word consciousness.
- 46:06Speaker 2: Mm.
- 46:07Speaker 4: Like if it means, like, you know, being able to
- 46:09Speaker 4: write poetry and understand Shakespeare, that's one you might not
- 46:13Speaker 4: get very far there. But you know, I've talked to
- 46:15Speaker 4: scientists basically, just define it as our sense are as
- 46:22Speaker 4: one of our senses that keeps track of our internal state.
- 46:28Speaker 4: So like you have a visual sense that tells you, oh,
- 46:30Speaker 4: I'm in the room, there's a door over there, that's
- 46:33Speaker 4: an apple over there. You have kind of an inner
- 46:35Speaker 4: looking sense that just tells you like, oh, I'm feeling
- 46:38Speaker 4: this way, I'm thinking about this, I'm having this memory
- 46:41Speaker 4: of the apple eight this morning. It's just kind of
- 46:44Speaker 4: like something that tells your body, Oh, this is what's
- 46:46Speaker 4: going on inside your brain.
- 46:48Speaker 3: Well, the key word there also is I you know,
- 46:51Speaker 3: and this idea of identity and this idea of consciousness
- 46:54Speaker 3: revolving around.
- 46:55Speaker 2: Who we are and when who we are.
- 46:57Speaker 3: Being ultimately a collection of experience is that are in
- 47:01Speaker 3: many ways influenced by the society we live in and
- 47:04Speaker 3: you know, and if you want to take it further
- 47:05Speaker 3: than them people trying to achieve enlightenment, the idea is
- 47:07Speaker 3: sort of disconnect from all of those aspects and like
- 47:10Speaker 3: truly experience the spiritual part of what it is to
- 47:14Speaker 3: have me have a soul or to like, you know,
- 47:15Speaker 3: what it means to be part of the universe, rather
- 47:18Speaker 3: than this identity, this construct that we sort of you know,
- 47:21Speaker 3: force upon ourselves or is forced upon us oftentimes.
- 47:25Speaker 2: It's fascinating. Obviously I'm super into this.
- 47:28Speaker 4: Well did this gets We just did an episode about
- 47:30Speaker 4: this on Signed Stuff, the podcast on and about near
- 47:35Speaker 4: death experiences.
- 47:37Speaker 2: Oh, we just.
- 47:38Speaker 3: Talked to an incredible podcast creator and friend of the show,
- 47:42Speaker 3: Dan Bush on stuff that I want you to know
- 47:43Speaker 3: about his incredible podcasts Alive Again. That is all about
- 47:47Speaker 3: interviews with folks who've experienced your experiences.
- 47:50Speaker 1: I'm going to connect you with those folks. You guys
- 47:53Speaker 1: should hang out can you tell us just a bit
- 47:56Speaker 1: of a tease as we wrap up what you found
- 48:00Speaker 1: in your explorations on ND or near death experiences in
- 48:05Speaker 1: science stuff.
- 48:06Speaker 4: Yeah, well, it kind of goes back to this idea
- 48:08Speaker 4: of what consciousness is and because you know, a big
- 48:11Speaker 4: part of near death experiences is this out of body experience.
- 48:14Speaker 4: People feel like they're outside their body, and what we
- 48:17Speaker 4: found was that it can it can all be explained
- 48:22Speaker 4: by science by how your brain works, and but whether
- 48:27Speaker 4: that's actually what's going on, like you know, scientists can't
- 48:30Speaker 4: answer that because you know, we can't test someone while
- 48:33Speaker 4: they're having it experience. But basically all of these phenomena
- 48:37Speaker 4: near thats you know, feeling outside of your body, having
- 48:40Speaker 4: weird visions, talking to people who are already dead, there
- 48:46Speaker 4: are brain processes that you can say, Okay, I think
- 48:49Speaker 4: that's what's going on there, and that we can replicate
- 48:51Speaker 4: that in the lab. If I give you, you know,
- 48:54Speaker 4: a hallucinogen, well in a control environment, you're also going
- 48:58Speaker 4: to have these experiences. If I take i'm achine that
- 49:01Speaker 4: disrupts this part of your brain, I can make you
- 49:03Speaker 4: feel like you're stepping outside your body.
- 49:05Speaker 1: Or experiencing divinity like the famous god helmet experiments, and
- 49:11Speaker 1: and also very well done doctor cham to note that
- 49:15Speaker 1: we cannot ethically pursue some direct experiments that would lead
- 49:22Speaker 1: to breakthroughs there because it would require doing kind of
- 49:29Speaker 1: evil things to innocent people, even if they signed up.
- 49:32Speaker 1: You know, we've all seen flatliners. Yeah, classic Julia Roberts movie. Yeah,
- 49:38Speaker 1: oh yeah, that was joy, that was yeah, young Sutherland,
- 49:43Speaker 1: Yeah yeah yeah. And uh, you know, I've got to
- 49:47Speaker 1: be honest. Uh, it's a super up to date pop
- 49:50Speaker 1: culture reference, I'm sure, but I remember seeing flatliners and
- 49:57Speaker 1: being convinced that this is why people join med school and.
- 50:03Speaker 2: So they can do the flat so they can do flatliners.
- 50:05Speaker 1: Yeah. Luckily, Luckily, my uncle, a very nice, very learned man,
- 50:12Speaker 1: assured a young Ben Bullen that it would still be
- 50:16Speaker 1: illegal to quote unquote flat line people to quote unquote
- 50:21Speaker 1: see what happens.
- 50:23Speaker 2: Well, And speaking of other cinematic masterpieces, we were talking
- 50:26Speaker 2: a little earlier about the idea of Vibes, and I
- 50:28Speaker 2: have to take this opportunity to recommend the movie Vibes.
- 50:31Speaker 2: Oh my god, it's one of your favorites, Ben. I
- 50:33Speaker 2: actually recommended it to a friend the other day.
- 50:36Speaker 3: Seminole Ghostbusters slash Indiana Jones mashup slash Ripoff that everyone
- 50:41Speaker 3: should see, starring Jeff Goldbloom and Cindy Love Hare, No
- 50:47Speaker 3: True No Vibes. Well, get you to a cinema or hey,
- 50:52Speaker 3: hopefully they're doing a revival screening of Vibes somewhere in
- 50:55Speaker 3: your neck of the woods.
- 50:56Speaker 4: I think I missed that seminal moment in neuroscience.
- 50:59Speaker 2: It's okay, Yeah, it explains a lot. It's a real breakthrough.
- 51:05Speaker 1: It's sort of like the Police Academy four of its time.
- 51:09Speaker 2: It's probably contemporary with Police Academy. It probably is. Actually
- 51:13Speaker 2: I've come out the same year with that.
- 51:15Speaker 1: Thank you so much, Orgee for spending time with us
- 51:19Speaker 1: and making this Orgey and Science Stuff Week. Where can
- 51:23Speaker 1: people learn more about your explorations.
- 51:28Speaker 4: Yeah, so right now my big project is sign Stuff.
- 51:31Speaker 4: It's a new iHeart podcast. You can find it anywhere
- 51:34Speaker 4: you get your podcasts. Search for sign Stuff one word
- 51:37Speaker 4: and look for the purple icon. That's us. And we
- 51:41Speaker 4: asked her awesome questions like do animals understand death? Or
- 51:46Speaker 4: do they like to get drunk? Or what's inside of
- 51:48Speaker 4: a black hole? Or oh, grow limb Yeah, that's the
- 51:54Speaker 4: one that was super fascinating recently. Why can't we regrow limbs?
- 51:57Speaker 4: There are animals who, like you, cut up their arm,
- 52:00Speaker 4: don't just grow a brand new one. Why can't we
- 52:02Speaker 4: do it? And we find out the answer is maybe
- 52:05Speaker 4: we can.
- 52:06Speaker 1: And while you are on the internet, please do check
- 52:11Speaker 1: out one of our favorite aspects of Doctor Chimp or Hey.
- 52:18Speaker 1: In addition to being one of, if not the smartest
- 52:23Speaker 1: people on the history of this show, definitely in this episode.
- 52:27Speaker 1: You are not just a mechanical engineer Stanford graduated. You
- 52:34Speaker 1: did not just attend Georgia Tech, one of the most
- 52:39Speaker 1: difficult schools of its caliber. You are also the creator
- 52:44Speaker 1: of a comic strip called PhD Comics. Could you tell
- 52:47Speaker 1: us a little bit about that?
- 52:49Speaker 4: Yeah, PhD Comics. You can find out a PhD Comics
- 52:52Speaker 4: dot com. It's a comic strip I started when I
- 52:54Speaker 4: was in grad school, and it's all about what it's
- 52:58Speaker 4: like to do science, what it's like to be an academic.
- 53:01Speaker 4: It's kind of people describe it as the Dilbert of academia.
- 53:06Speaker 2: I don't know this, guys. I'll have to check it
- 53:07Speaker 2: out next trip in my life.
- 53:10Speaker 4: Yeah. Yeah, and so I was super lucky to be
- 53:12Speaker 4: able to do that for many many years on the internet,
- 53:15Speaker 4: huge amount of support for people out there, and then
- 53:18Speaker 4: that translated to me doing movies and then a TV show.
- 53:21Speaker 4: Recently you can find that one on PPS Kids. It's
- 53:24Speaker 4: called Eleanor Wonders Why. And I've also gone in to
- 53:28Speaker 4: write and draw a lot of books. So my probably
- 53:31Speaker 4: my most famous one I've worked on is called We
- 53:34Speaker 4: Have No Idea, which is a guide to everything we
- 53:37Speaker 4: don't know about the universe. And now the most popular
- 53:41Speaker 4: one is something called Oliver's Great Big Universe, which is
- 53:44Speaker 4: for kids. If you have a kid who's really curious
- 53:47Speaker 4: and like science but also likes, you know, far jokes
- 53:50Speaker 4: and really fun, fun middle school middle grade stories, please
- 53:55Speaker 4: check it out.
- 53:56Speaker 3: A polymath and renaissance man, indeed, doctor Horte Sham, thanks
- 54:01Speaker 3: again for joining us on Ridiculous History.
- 54:03Speaker 5: For Hoorte Sham week, oh thank you, and well well
- 54:08Speaker 5: well bully for us, congratulations and tally ho Wecei Thury, Yes,
- 54:17Speaker 5: Noel we once again, my friend, uh.
- 54:20Speaker 1: We managed to speak with a world class expert uh
- 54:26Speaker 1: in science, and I think we post some interesting questions.
- 54:31Speaker 3: I think so, I think we held our own with
- 54:33Speaker 3: doctor cham Jorge to his friends. I'd like to think
- 54:37Speaker 3: that we walked away from these recordings as friends. He said,
- 54:39Speaker 3: like said, he wanted to come back on again, and
- 54:41Speaker 3: that we made him laugh and smile.
- 54:43Speaker 2: That made us feel really good. That's true.
- 54:45Speaker 5: Our neurons were firing, were they which whichever part is associated.
- 54:51Speaker 1: With learning and with us?
- 54:53Speaker 2: And joy?
- 54:54Speaker 1: And joy? That's the word we were looking for. Uh
- 54:58Speaker 1: we I don't know. No, this guy is so close
- 55:01Speaker 1: to getting a cool ridiculous history, street name, a nickname,
- 55:05Speaker 1: an operator name.
- 55:06Speaker 2: You know it's doctor horget riverside Champ. Oh, that's true,
- 55:10Speaker 2: he made his own.
- 55:11Speaker 5: There we go.
- 55:12Speaker 3: Now we can do better, we'll workshop that one, but
- 55:15Speaker 3: for now. Huge days to you, Ben. That was a
- 55:18Speaker 3: fun exploration of all things heady and universal.
- 55:22Speaker 1: Huge thanks to you know, huge thanks to our super producer,
- 55:25Speaker 1: mister Max Frictionless. Williams got a nice haircut there. Also,
- 55:31Speaker 1: big big thanks to aj Bahama's Jacob's Jonathan Strickland aka
- 55:37Speaker 1: the Twister. Okay, yep, big thanks to him.
- 55:42Speaker 2: Oh yeah, of course. Sure, the rude dudes over a
- 55:45Speaker 2: ridiculous crime.
- 55:46Speaker 3: We've got Chris Praciota's and Eve Jeff Coates here and
- 55:48Speaker 3: Spirit you know what, I think.
- 55:51Speaker 4: We'll see you next time, folks.
- 55:59Speaker 3: For more podcast from iHeartRadio, visit the iHeartRadio app, Apple Podcasts,
- 56:03Speaker 3: or wherever you listen to your favorite shows.