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FDA Approves First Mutation-Driven Breast Cancer Drug | Dothan News

FDA just approved a groundbreaking new treatment for advanced breast cancer — Etcamah (camizestrant) — designed for patients whose cancer has developed an ESR1 mutation while on other therapies. This marks the first time the FDA has approved a cancer drug based on detecting resistance mutations in blood tests before imaging shows disease progression. The approval comes with a companion blood test, Guardant360 CDx, to identify eligible patients. Early data shows patients on Etcamah plus a CDK4/6 inhibitor had slower cancer progression compared to those continuing prior treatments. Developed by…

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