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AHR Brake Discovered for Nerve Regrowth | Science News
Scientists have uncovered a molecular brake in nerve cells — a protein called AHR — that halts regrowth after injury. When active, AHR prioritizes survival over repair, but blocking it in mice triggered axon regrowth in both peripheral and spinal cord injuries, restoring movement and sensation. This trade-off reveals how AHR’s stress-survival role stifles healing. Since adult mammal nerves rarely regenerate, this discovery could revolutionize treatments — especially as existing AHR-inhibiting drugs may be repurposed for nerve repair, pending further safety and efficacy research. Listen in…
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