Latest / Success Story with Scott Clary / Lessons - How Your DNA Holds the Key to Preventing Disease | Kashif Khan - Genetic Health Expert

Transcript

Lessons - How Your DNA Holds the Key to Preventing Disease | Kashif Khan - Genetic Health Expert · Success Story with Scott Clary

• 0:00
  In this lessons episode, discover how your lifestyle, not just your genes, shapes your risk for
• 0:04
  diseases like Alzheimer's. Learn how brain inflammation is often the root cause, how small changes
• 0:09
  in diet, stress, and environment can prevent chronic illness, and how your body is built to live longer
• 0:15
  than you think if you care for it the right way.
• 0:17
  I mean, I've heard you speak about Alzheimer's and dementia quite a bit, and I'm predisposed to that. I think to some degree,
• 0:34
  because I think my grandpa got it, and I actually did a DNA test of some sort, I can't remember which
• 0:41
  one it was, but it was showing like that was like the one thing that I should look out for.
• 0:45
  And I've thought about like lifestyle changes and food and whatnot, but I've never really considered
• 0:53
  environment. And I've never even thought that there's supplementation that could completely,
• 0:58
  or with a high degree of success find a way to sort of push off or delay Alzheimer's dementia.
• 1:06
  So you're saying that like, I'm sure you know a lot about this. There are like supplement combinations
• 1:12
  if you are in the proper environment and your health and wellness is sort of on point that you can
• 1:17
  actually push yourself even if you're predisposed to it. Perfect example of what is believed as possible,
• 1:22
  even at the medical level, the doctor tells you how you have this genetic worker, it speaks to an
• 1:27
  elevated risk of dementia, watch out, right? And the anxiety of that alone will cause the dementia,
• 1:32
  because that's one of the causes is high cortisol, right? So we really need to use that more as a
• 1:36
  priority, as opposed to a prescription, what biology actually leads to this outcome? So we reverse
• 1:43
  engineering. So what do we see? For, by the way, Chris Hemsworth, Thor, right? We used to do during
• 1:51
  our research a lot of work on the Marvel movie sets. So the trainers or the stars would,
• 1:56
  we'd work with them to build these cocktails to keep people at their best so that you know those
• 1:59
  long shoot days, they had good recovery, good everything, good energy, good sleep. And so because of
• 2:04
  that, the one of the producer that made the show limitless, remember Chris put on the show, right?
• 2:08
  We were supposed to work on that show on the genetic episode and then COVID hit production got shut
• 2:13
  down. Chris is in Australia. I said, do you want, I'm going to just do it anyway. I'm going to
• 2:16
  pick up some cameras with my buddies and that's what he did. So in that episode where he did the
• 2:21
  genetic test, he was told you have the APO aging, right? The Alzheimer's. I know that was like a
• 2:27
  big story. It was a tabloid story. Yeah. Everybody has the gene. What version you have determines what
• 2:33
  clinicians will say is a very low risk, eight to 10 times risk or 17 to 25 times risk of getting
• 2:39
  dementia versus the average population. If you ask that doctor that told Chris that nice,
• 2:44
  literally sent an email to the producer saying, I just watched this episode. This is nonsense.
• 2:47
  There's so much more, right? Here's what I told them that yes, this gene is linked to people
• 2:53
  that have Alzheimer's because we only study things in a disease-centric setting. Farmer companies
• 2:58
  don't study healthy people to ask them why they didn't get sick. They study people with a disease
• 3:03
  and figure out what genes are tied to it because that helps them make pills, right? But that's too late.
• 3:08
  What does this gene do? This gene is responsible for lipid transport, so moving cholesterol in your body,
• 3:14
  literally moving it around. So everybody has this. Everybody has this gene, right? If you have
• 3:18
  inflammation in your brain, this gene is responsible to send cholesterol there to fight the inflammation.
• 3:24
  Clestrol is a very beneficial hormone that fixes things all of your body. It's also a root for
• 3:29
  your sex hormones like testosterone, et cetera. It's also good for your brain, right? If you have the
• 3:34
  bad transport tool, you don't do a good job of transport. And so when you have the inflammation,
• 3:39
  the cholesterol deployed, it's easier for some to get less behind, left behind, I should say,
• 3:43
  and start to build what we call an AMOLED plaque, this plaque in your brain. That plaque
• 3:48
  starts to choke at the brain cells, kill the brain cells, and eventually lead to cognitive decline.
• 3:53
  And the behavior that a doctor will call Alzheimer's. But if you actually reverse engineer it,
• 3:57
  step one, why did I have inflammation in my brain? If that didn't happen, I didn't need to worry
• 4:03
  about what version of this gene that I had, which only comes from this disease-centric thinking,
• 4:08
  which is where research money goes, right? So what causes the brain inflammation? Do you have
• 4:12
  leaky gut, like I did, which is why I had brain frog and depression? Talks and exiting your
• 4:18
  gut wall, crossing the blood brain barrier, causing brain inflammation. That's one big cause.
• 4:23
  Do you have high stress, constant high cortisol, which is another source of brain inflammation?
• 4:28
  You need to tone that down. Metabolically dysfunctional. What are you eating? And what are your
• 4:33
  unique genetics saying about your ability to process those things? Some people decide to become
• 4:37
  a vegan. Some people decide to go to a keto diet when their genes actually don't allow them to
• 4:42
  do that. And they're going to get sick from that thing, right? Fourth is environmental. This is
• 4:47
  probably the big, big underlying one that most people don't realize. There's a gentleman named Dr.
• 4:52
  Tom O'Brien, who's one of the sort of pioneers of the functional medicine movement. And he did
• 4:57
  some research in California and said that 66% of California's dementia is based on what
• 5:01
  thing people are breathing. One hour of LA traffic is an equivalent to a pack of cigarettes.
• 5:08
  In terms of the amount of inflammation it causes. When you do that day in and day out,
• 5:11
  the brain inflammation just increased. The last one in the big one.
• 5:16
  This is why 80% of dementia cases are in women is because your hormones that are meant to benefit
• 5:22
  you can cause inflammation if you're not doing the activity that your hormones are designed for.
• 5:28
  And some women make toxic estrogens that can reside in your brain cause inflammation.
• 5:32
  So all of these five things, so when I got your gene results, say we were working back then,
• 5:36
  when you got your thing, I was like, okay, park this. Don't worry. Let's look at these five things.
• 5:42
  If we plug the gaps and holes on these five things with either the right supplement or the
• 5:46
  removal of the wrong habit or cleaning up the environment, whatever your priority is, it's not happening.
• 5:51
  No in root brain information. You don't have brain information now, which is why you don't
• 5:54
  have dementia now. Once you get to a certain age, your mitochondria, the energy that's in the brain,
• 6:00
  starts to also reduce. So the ability to fight the inflammation changes. And that's why it's an
• 6:04
  old age disease. So if you start to look at all these little pieces of what's the biology actually
• 6:09
  driving the net outcome, you can work on each step and then it becomes a choice. You don't need to
• 6:13
  have this thing that you're told you have a risk for. So all all all these predispose like predispose
• 6:19
  to cancer, predispose to heart disease. There are all things that can be mitigated to some degree.
• 6:25
  So there is some truth to genetic conditions, right? That is less than 3% of healthcare.
• 6:32
  According to the CDC, 90% of the $4.3 trillion healthcare budget in the United States is spent on
• 6:38
  chronic disease management. Things that are caused that we do not need to have you're not born with
• 6:44
  it. It's not in you. You cause it. No fault of your own. You didn't know any better. What you ate,
• 6:49
  what you breed, the toxic people you're surrounded yourself by, whatever it was, caused the
• 6:53
  inflammation to cause a disease. So if we can eliminate that in the United States of the top 15
• 7:00
  reasons why people die, 14 are rooted in inflammation. So if you don't have inflammation,
• 7:08
  when whatever part of your body, which leads to whatever disease, those are all off the table.
• 7:13
  And that all of a sudden you go from a, like you said, this expectation that you get your first
• 7:18
  chronic disease at 55, which is the American average, second by 65, and you spend the last 15 years
• 7:24
  of your life in treatment. That is the norm. Versus a few simple tweaks and all of a sudden you jump
• 7:30
  from 78 average life expectancy to 90. Like I don't smoke. I eat clean. I exercise three times a
• 7:37
  week. And this literally by the way is a result of a Harvard study. They studied a bunch of nine
• 7:41
  year old plus people. And they said, here's the five things they didn't smoke. They exercise more
• 7:46
  than three days a week. They drank less than three drinks a week. They were not obese. And they
• 7:51
  had a healthy whole food diet. That was it. I got them from 70 to N. The 70 to 90 was 90 with good health.
• 7:58
  Not 78 in a hospital bit. So without even doing a DNA test, I mean, like if you just adopt these like
• 8:05
  five lifestyle changes, which just seemed to be smart comments and all things. So this is already
• 8:10
  going to fix the majority of the problems in your life and the majority of causes for information.
• 8:16
  It's that you remove the modern conveniences that are making us sick. I was going to say it seems
• 8:21
  like our whole life is actually so it's ironic because everything you just mentioned is so common
• 8:24
  sense and so easy. But our whole life and most people's lives are shitty food, stressful environment.
• 8:32
  And we just go through it every single day. I think and I think that intuitively we always think,
• 8:36
  oh, I'll get better. And I'll be less stressed and I'll work less and I'll eat better.
• 8:40
  I'll do it later. I'll put it off, right? Yeah. To prevent all simers in your 60s, you need to start
• 8:46
  working on your health on your 35. Right? Because the chronic disease is not a switch that gets
• 8:50
  turned on over time that your body is able to fight and is resilient at that age and can tone it
• 8:56
  down that all sudden the disease wins. And one last thought there is that the sort of kicker to all
• 9:02
  this is yes, adopt healthy habits. The last bit that people need to know is that some things that
• 9:08
  you think are healthy that is good for somebody else is actually bad for you. That's the X factor
• 9:13
  where you got that's the X to yeah. And that's the thing where that's how you get from 90 to 120.
• 9:18
  If you look at actually RNA to cells, aging is the degradation of DNA. So damaged oxidization
• 9:25
  environmental wear and tear. There's these caps on our DNA called telomeres that are like bumpers
• 9:29
  wear and tear. They're physically designed to last 120 years. So we know that our cells are
• 9:35
  designed to last 120 years. That's what we're supposed to get to measuring those can indicate your
• 9:40
  biological exactly. Okay. So that's why we use this for biological age measurement. We know
• 9:45
  they're supposed to last 120. So if we already know that we know 120 is what we're wired for.
• 9:50
  And it's supposed to be 120 and you see it. We're grilling ourselves. We are taking years away
• 9:55
  that we already have as a God-given gift. Thanks for tuning in. If you found this valuable,
• 9:59
  don't forget to hit that subscribe button so you never miss an episode. And if you want to dive
• 10:03
  deeper into this conversation, check out the links in the description to watch the full episode.
• 10:08
  See you in the next one.