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NEJM Oct 22 2026 Ianalumab for the Treatment of Patients with Sjögren’s Disease
Two clinical studies, NEPTUNUS-1 and NEPTUNUS-2, evaluated the effectiveness of the antibody ianalumab as a potential medical intervention for Sjögren's disease, a complicated autoimmune condition lacking specialized treatments. Researchers divided hundreds of participants into groups to compare monthly or quarterly subcutaneous injections of the medication against a placebo over the course of a year. The primary objective measured changes in disease activity scores at week 48 using standardized rheumatology indexes. Findings revealed that monthly dosesachieved a statistically significant…
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