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The Second European Carotid Surgery Trial (ECST-2)
This text summarizes interim results from the Second European Carotid Surgery Trial (ECST-2), a multicenter randomized trial comparing optimized medical therapy (OMT) alone versus OMT plus revascularization for patients with asymptomatic or low-to-intermediate risk symptomatic carotid stenosis of 50% or greater. The trial used the Carotid Artery Risk (CAR) score to identify patients predicted to have a 5-year stroke risk of less than 20%. The 2-year interim analysis, utilizing a hierarchical outcome and win ratio method, found no significant evidence that adding revascularization to OMT…
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