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Latest / WhiteBoard Medicine - Emergency And Critical Care

#254 Sickle Cell Crisis Explained | VOC, Acute Chest Syndrome & Emergencies Made Simple

In this episode, we break down sickle cell crisis and life-threatening complications, including vaso-occlusive crisis (VOC), acute chest syndrome (ACS), splenic sequestration, aplastic crisis, and infection. We walk through the underlying pathophysiology of sickle cell disease, why these emergencies occur, and how to recognize and manage them in the emergency department and ICU. This is a high-yield, practical framework to help you quickly distinguish common presentations from life-threatening complications. If you’re a medical student, resident, nurse, or practicing clinician, this episode…

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